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FDA approves blood-based cobas EGFR Mutation Test v2 for NSCLC patients

The U.S. Food and Drug Administration today approved the cobas EGFR Mutation Test v2, a blood-based companion diagnostic for the cancer drug Tarceva (erlotinib). This is the first FDA-approved, blood-based genetic test that can detect epidermal growth factor receptor (EGFR) gene mutations in non-small cell lung cancer patients.

2 Jun 2016

New drugs show promise as first antidote for radiation exposure

University of Virginia School of Medicine researchers have identified promising drugs that could lead to the first antidote for radiation exposure that might result from a dirty bomb terror attack or a nuclear accident such as Chernobyl.

2 Jun 2016

Duke scientists discover new small-molecule drugs to treat chronic pain

A research team at Duke University has discovered a potential new class of small-molecule drugs that simultaneously block two sought-after targets in the treatment of pain.

1 Jun 2016

Denosumab drug that inhibits RANKL gene can prevent genetic breast cancer

An international team led by researchers at the Austrian Institute of Molecular Biotechnology in Vienna and the University of Maryland School of Medicine in Baltimore discovered that genetically determined breast cancer can be largely prevented by blocking a bone gene. An already approved drug could be quickly available and would then be the first breast cancer prevention drug.

1 Jun 2016

Understanding how opiates affect brain pathways to drive addiction cycle

New research by Steven Laviolette's research team at Western University is contributing to a better understanding of the ways opiate-class drugs modify brain circuits to drive the addiction cycle.

1 Jun 2016

Ocaliva drug gets FDA approval for primary biliary cholangitis treatment

On Friday, May 27, the U.S. Food and Drug Administration granted accelerated approval for Ocaliva (obeticholic acid) for the treatment of primary biliary cholangitis (PBC) in combination with ursodeoxycholic acid (UDCA) in adults with an inadequate response to UDCA, or as a single therapy in adults unable to tolerate UDCA.

1 Jun 2016

TSRI scientists develop first drug candidate that neutralizes disease-causing RNA repeats

In an important new study with implications for the treatment of dozens of incurable diseases, scientists from the Florida campus of The Scripps Research Institute have for the first time created a drug candidate that attacks and neutralizes the RNA structure that causes an incurable progressive, inherited disease involving a gradual loss of control over body movement.

1 Jun 2016

BetterYou wins top prize at Veggie Awards for TotalNutrition Superfood powder

A unique blend of organically harvested superfoods created by health pioneers BetterYou, has scooped the top prize in the Best Supplement category at the Veggie Awards, a true mark of quality in the meat-free industry.

From BetterYou Ltd 1 Jun 2016

AbbVie, Sanofi and Novo Nordisk listed among top 10 companies in 2016 UK Pharma RepTrak rankings

AbbVie, Sanofi and Novo Nordisk top the RepTrak® ranking of the most reputable pharmaceutical companies in the UK, Reputation Institute announced today, based on more than 1,600 ratings collected in the first quarter of 2016 from members of the UK general public.

1 Jun 2016

Study identifies persistent opioid use in some patients after knee or hip replacement

Many patients undergoing hip or knee replacement are still taking prescription opioid pain medications up to six months after surgery, reports a study in PAIN, the official publication of the International Association for the Study of Pain.

1 Jun 2016

Additional drug treatment options to prevent migraine may offer hope to sufferers

Preventing or shortening the duration of migraine attacks - established drug treatment options and those that could shape future therapies were discussed at the Congress of European Academy of Neurology in Copenhagen.

1 Jun 2016

Gonorrhoea infections increase across Europe

Since 2008, the overall rate of reported gonorrhoea infections has more than doubled across Europe, going up from 8 per 100 000 population to 20 cases per 100 000 persons in 2014.

1 Jun 2016

Folic acid intake during pregnancy could protect children from possible side-effect of antiepileptic drugs

If pregnant women take antiepileptic drugs, the child can develop autistic traits. The administration of folic acid preparations appears to be a suitable means of preventing this serious side-effect. This finding is suggested by a Norwegian study presented at the Congress of the European Academy of Neurology in Copenhagen.

1 Jun 2016

Vital compound in common anti-inflammatory drugs can combat cancer, inflammation

Scientists from the Gladstone Institutes have identified a new pathway by which salicylic acid--a key compound in the nonsteroidal anti-inflammatory drugs aspirin and diflunisal--stops inflammation and cancer.

1 Jun 2016

Majority youths with autism or intellectual disability receive antipsychotics, study finds

About one in ten youths treated with an antipsychotic are diagnosed with autism spectrum disorder or intellectual disability. Conversely, one in six youths diagnosed with autism spectrum disorder has been prescribed antipsychotics.

31 May 2016

Study finds decrease in Google searches for chickenpox after vaccination implementation

Countries that implement government-mandated vaccinations for chickenpox see a sharp drop in the number of Google searches for the common childhood disease afterward, demonstrating that immunization significantly reduces seasonal outbreaks.

31 May 2016

Brief opioid exposure can cause increase in chronic pain

The dark side of painkillers - their dramatic increase in use and ability to trigger abuse, addiction and thousands of fatal overdoses annually in the United States is in the news virtually every day.

31 May 2016

Patients undergoing breast cancer surgery with non-opiate anaesthesia may need less painkillers

New research presented at Euroanaesthesia 2016 shows that patients undergoing breast cancer surgery need less painkilling medication post-surgery if they have anaesthesia that is free of opioid drugs.

31 May 2016

Improving regulatory environment and raising the role of self-care could relieve pressure on worldwide healthcare systems

A white paper, written by the Economist Intelligence Unit (EIU) and released today reports that greater regulatory harmonisation and access to non-prescription medicines as a whole could improve the ability of patients to care for themselves and reduce needless costs to society, health systems, individuals and companies. Consumer Health: time for a regulatory re-think?, which is based on in-depth interviews with international experts from industry bodies, regulators, academia and patient groups, concludes that self-care and the topic of consumer health regulation is not receiving sufficient attention.

30 May 2016

SIPPET study may have implications for treatment of patients with severe hemophilia A

SIPPET, a study which involved 42 centers in 14 countries in Europe, North and South America, Africa and Asia was designed to definitively settle the long-debated question whether factor VIII concentrates from different sources (plasma-derived containing VWF or recombinant technology) differ in risk of inhibitor development in previously untreated children (PUPs) with severe hemophilia A.

28 May 2016

Pharmaceutical News

FDA approves blood-based cobas EGFR Mutation Test v2 for NSCLC patients

New drugs show promise as first antidote for radiation exposure

Duke scientists discover new small-molecule drugs to treat chronic pain

Denosumab drug that inhibits RANKL gene can prevent genetic breast cancer

Understanding how opiates affect brain pathways to drive addiction cycle

Ocaliva drug gets FDA approval for primary biliary cholangitis treatment

TSRI scientists develop first drug candidate that neutralizes disease-causing RNA repeats

BetterYou wins top prize at Veggie Awards for TotalNutrition Superfood powder

AbbVie, Sanofi and Novo Nordisk listed among top 10 companies in 2016 UK Pharma RepTrak rankings

Study identifies persistent opioid use in some patients after knee or hip replacement

Additional drug treatment options to prevent migraine may offer hope to sufferers

Gonorrhoea infections increase across Europe

Folic acid intake during pregnancy could protect children from possible side-effect of antiepileptic drugs

Vital compound in common anti-inflammatory drugs can combat cancer, inflammation

Majority youths with autism or intellectual disability receive antipsychotics, study finds

Study finds decrease in Google searches for chickenpox after vaccination implementation

Brief opioid exposure can cause increase in chronic pain

Patients undergoing breast cancer surgery with non-opiate anaesthesia may need less painkillers

Improving regulatory environment and raising the role of self-care could relieve pressure on worldwide healthcare systems

SIPPET study may have implications for treatment of patients with severe hemophilia A

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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