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Prospective biobank studies with genetic data can help improve drug development, reduce costs

With drug development costs topping $1.2bn (£850 million) to get a single treatment to the point it can be sold and used in the clinic, could genetic analysis save hundreds of millions of dollars?

15 Jun 2016

Already-approved drugs can fight apoptosis evasion in cancer

Cancer cells don't die when they're supposed to. Animal and human bodies follow an orderly process of birthing new cells and killing old ones. But cancer cells escape programmed cell death, called apoptosis, and multiply uncontrollably.

15 Jun 2016

Study ignores possibility that drugs, chemicals affect sexes differently

Many of the medicines we take were only ever tested on men during clinical studies. This poses a distinct danger that females are receiving suboptimal care—and that treatments specifically benefiting women are going undiscovered.

15 Jun 2016

Maternal SRI treatment may cause microscopic changes in fetal brain structure

A new Finnish study shows that fetal exposure to commonly used SRI drugs may affect brain activity in newborns. The researchers suggest that the effects of drugs on fetal brain function should be assessed more carefully.

15 Jun 2016

Cranberries can reduce symptomatic UTIs and avoid chronic suppressive antibiotics

Today leading experts on infectious disease and urinary tract infections (UTIs) will gather in London to discuss the alarming state of antibiotic resistance, and present findings from a landmark study that conclusively shows that cranberries can be a nutritional approach to reducing symptomatic UTIs, and as a result, may be a useful strategy to decrease worldwide use of antibiotics.

15 Jun 2016

Immunotherapy drugs given after chemotherapy may benefit ovarian cancer patients

Women with advanced ovarian cancer may benefit more from immunotherapy drug treatments if they are given straight after chemotherapy, according to a new study published in Clinical Cancer Research today.

15 Jun 2016

Blood pressure medications can lower stroke, heart attack risk in patients with end-stage renal disease

Two classes of blood pressure medications, angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs), are associated with a 16% lower risk of strokes, heart attacks and death in patients with end-stage renal disease who are undergoing peritoneal dialysis, a new study in the journal, Nephrology Dialysis Transplantation, reports.

15 Jun 2016

Emergence of multidrug-resistant salmonella strains increases burden of neglected diseases in Africa

"The affected countries will have a major problem if we do not manage to control salmonella bloodstream infections with new antibiotics such as ciprofloxacin," cautions Prof Jürgen May.

15 Jun 2016

New and inexpensive technique could help meet global demands for malaria drug

A new and inexpensive technique for mass-producing the main ingredient in the most effective treatment for malaria, artemisinin, could help meet global demands for the drug, according to a study to be published in the journal eLife.

15 Jun 2016

Study characterizes benefits of over-the-counter sleep aid

New research shows that an over-the-counter sleep aid helps people suffering from occasional sleep difficulties fall asleep in less than 20 minutes, on average, and improves their reported quality of sleep.

15 Jun 2016

Creating essential medicines list can help protect against drug shortages

Queen's University researcher Jacalyn Duffin and colleagues are recommending that Canada create a list of essential medicines to help protect against drug shortages.

15 Jun 2016

NCMC develops national roadmap for large-scale manufacturing of cell-based therapeutics

An industry-driven consortium has developed a national roadmap designed to chart the path to large-scale manufacturing of cell-based therapeutics for use in a broad range of illnesses including cancer, neuro-degenerative diseases, blood and vision disorders and organ regeneration and repair.

15 Jun 2016

Opioid use common among Medicare beneficiaries after hospital discharge

Nearly 15 percent of opioid-naïve patients hospitalized under Medicare are discharged with a new prescription for opioids, according to a study published today in JAMA Internal Medicine.

15 Jun 2016

New survey reveals more than half of patients prescribed opioids have leftover pills

In the midst of an epidemic of prescription painkiller addiction and overdose deaths, a new Johns Hopkins Bloomberg School of Public Health survey suggests that more than half of patients prescribed opioids have leftover pills -- and many save them to use later.

14 Jun 2016

Pharmaceutical News

Prospective biobank studies with genetic data can help improve drug development, reduce costs

Already-approved drugs can fight apoptosis evasion in cancer

Study ignores possibility that drugs, chemicals affect sexes differently

Maternal SRI treatment may cause microscopic changes in fetal brain structure

Cranberries can reduce symptomatic UTIs and avoid chronic suppressive antibiotics

Immunotherapy drugs given after chemotherapy may benefit ovarian cancer patients

Blood pressure medications can lower stroke, heart attack risk in patients with end-stage renal disease

Emergence of multidrug-resistant salmonella strains increases burden of neglected diseases in Africa

New and inexpensive technique could help meet global demands for malaria drug

Study characterizes benefits of over-the-counter sleep aid

Creating essential medicines list can help protect against drug shortages

NCMC develops national roadmap for large-scale manufacturing of cell-based therapeutics

Opioid use common among Medicare beneficiaries after hospital discharge

New survey reveals more than half of patients prescribed opioids have leftover pills

NLCs packed with melatonin could increase effectiveness of tamoxifen drug

Darapladib drug can protect against vision loss in diabetic patients

Databases of proteins' 3-D shapes help identify more than 850 DNA mutations linked to cancer

Topical delivery of AVR drug combination can provide complete protection against HIV

Researchers aim to protect kidneys while improving cisplatin's efficacy against cancer

New experimental antibiotic can help combat MRSA infections

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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