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Smart drugs have lasting side-effects on young people's brain

Over a million American students misuse prescription drugs or take illegal stimulants to increase their attention span, memory, and capacity to stay awake. Such "smart drugs" become more and more popular due to peer pressure, stricter academic requirements, and the tight job market. But young people who misuse them risk long-term impairments to brain function, warn Kimberly Urban at the University of Delaware and Wen-Jun Gao at Drexel University College of Medicine, USA, in a NIH-funded review published in the open-access journal Frontiers in Systems Neuroscience.

14 May 2014

USC/NYU researchers develop small molecule that interferes with cancer progression with minimal side effects

A team of researchers from USC and NYU has developed and patented a small molecule that interferes with cancer progression with minimal side effects.

14 May 2014

Several medications can help people with alcohol use disorders quit drinking

Several medications can help people with alcohol use disorders maintain abstinence or reduce drinking, according to research from the University of North Carolina at Chapel Hill.

14 May 2014

Scientists find new drug that improves effectiveness of radiotherapy in stopping tumor growth

Scientists from The University of Manchester - part of the Manchester Cancer Research Centre - have demonstrated the potential of a drug to improve the effectiveness of radiotherapy in stopping tumour growth.

13 May 2014

Parent disapproval linked to lower rate of drug misuse among teens

Parents' attitudes toward substance use may help to explain observed racial/ethnic variations in prescription drug misuse among teens, reports a study in the May Journal of Developmental & Behavioral Pediatrics, the official journal of the Society for Developmental and Behavioral Pediatrics.

13 May 2014

Study on aspirin may offer hope to develop drugs that promote healing of chronic wounds in humans

In addition to its known capacity to promote bleeding events, aspirin also inhibits wound healing. New research published in The Journal of Experimental Medicine now describes how aspirin acts on key skin cells called keratinocytes, delaying skin repair at wound sites.

13 May 2014

Researchers identify several target molecules suitable for development of new allergy drugs

Researchers have identified several target molecules which are suitable for the development of new allergy drugs. The Journal of Allergy and Clinical Immunology, the most prestigious journal in the field of allergology, has recently published an extensive review article on the prospects of drug therapy for allergy.

13 May 2014

New breakthrough offers easier way of detecting pathogenic bacteria outside clinical setting

The breakthrough, published in the journal Nature Materials, could offer an easier way of detecting pathogenic bacteria outside of a clinical setting and could be particularly important for the developing world, where access to more sophisticated laboratory techniques is often limited.

13 May 2014

Research may offer unique pathway for targeting new therapeutics for addiction treatment

A research team from the Friedman Brain Institute of the Icahn School of Medicine at Mount Sinai has published evidence that shows that subtle changes of inhibitory signaling in the reward pathway can change how animals respond to drugs such as cocaine.

13 May 2014

Perrigo receives final approval from FDA for azelastine hydrochloride nasal spray ANDA

Perrigo Company plc announced that it has received final approval from the U.S. Food and Drug Administration on its Abbreviated New Drug Application (ANDA) for azelastine hydrochloride nasal spray (0.15%).

12 May 2014

Abeona Therapeutics obtains FDA Orphan Drug Designations for Sanfilippo Syndrome therapies

Abeona Therapeutics, a start-up company created around intellectual property licensed from Nationwide Children's Hospital to develop treatments for Sanfilippo Syndrome Types A and B, has been granted Orphan Drug Designations for its lead investigational therapies by the U.S. Food and Drug Administration Office of Orphan Products Development.

12 May 2014

Aratana initiates pivotal field effectiveness study for AT-001

Aratana Therapeutics, Inc., a pet therapeutics company focused on the licensing, development and commercialization of innovative biopharmaceutical products for cats, dogs and other companion animals, today announced the initiation of the pivotal field effectiveness study for AT-001 (grapiprant), the company's innovative drug for treating pain in dogs with osteoarthritis.

12 May 2014

Spring Bank announces 3 presentations on SB 9200 at 27th ICAR

Spring Bank Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company committed to discovering and developing novel drugs to treat a number of medical conditions, with a primary focus in antivirals, today announced three presentations on SB 9200, its lead drug candidate for the treatment of Hepatitis B (HBV) and Hepatitis C (HCV) infections, at the 27th International Conference on Antiviral Research (ICAR) being held May 12-16, 2014 at the Raleigh Convention Center in Raleigh, NC.

12 May 2014

Coronary artery calcium score may help guide aspirin therapy, finds new research

For over 30 years, aspirin has been known to prevent heart attacks and strokes, but who exactly should take a daily aspirin remains unclear. New research published today in Circulation: Cardiovascular Quality and Outcomes shows that your coronary artery calcium (CAC) score, a measurement of plaque in the arteries that feed the heart, may help determine whether or not you are a good candidate for aspirin.

12 May 2014

Experimental antibody temporarily halts progression of neuroblastoma in children

Tumors shrank or disappeared and disease progression was temporarily halted in 15 children with advanced neuroblastoma enrolled in a safety study of an experimental antibody produced at St. Jude Children's Research Hospital.

9 May 2014

Grace introduces ProVance Pre-packed Protein A Columns for mAb purification

W. R. Grace & Co. has introduced ProVance Pre-packed Protein A Columns, for purification of biologic drugs, specifically monoclonal antibodies (mAbs). Monoclonal antibodies represent the single largest biologics therapeutic category in the clinical development pipeline.

9 May 2014

AbbVie seeks marketing approval from EMA for all-oral, interferon-free therapy to treat HCV infection

AbbVie submitted marketing authorization applications (MAAs) to the European Medicines Agency seeking approval for the company’s investigational, all-oral, interferon-free regimen for the treatment of adult patients with chronic genotype 1 (GT1) hepatitis C virus (HCV) infection.

9 May 2014

Study: Anti-inflammatory compound interleukin-10 plays crucial role in regenerative, scarless healing

The powerful anti-inflammatory compound interleukin-10 (IL-10) plays a crucial role in regenerative, scarless healing of fetal skin.

9 May 2014

Single-cell genomics study confirms that immune cells produce steroids

Researchers at the European Bioinformatics Institute (EMBL-EBI) and the Wellcome Trust Sanger Institute have discovered that some immune cells turn themselves off by producing a steroid.

9 May 2014

Study: Pravastatin slows down growth of kidney cysts in children, young adults with ADPKD

Results from a study by University of Colorado School of Medicine researchers show that pravastatin, a medicine widely used for treatment of high cholesterol, also slows down the growth of kidney cysts in children and young adults with autosomal dominant polycystic kidney disease (ADPKD).

9 May 2014

Pharmaceutical News

Smart drugs have lasting side-effects on young people's brain

USC/NYU researchers develop small molecule that interferes with cancer progression with minimal side effects

Several medications can help people with alcohol use disorders quit drinking

Scientists find new drug that improves effectiveness of radiotherapy in stopping tumor growth

Parent disapproval linked to lower rate of drug misuse among teens

Study on aspirin may offer hope to develop drugs that promote healing of chronic wounds in humans

Researchers identify several target molecules suitable for development of new allergy drugs

New breakthrough offers easier way of detecting pathogenic bacteria outside clinical setting

Research may offer unique pathway for targeting new therapeutics for addiction treatment

Perrigo receives final approval from FDA for azelastine hydrochloride nasal spray ANDA

Abeona Therapeutics obtains FDA Orphan Drug Designations for Sanfilippo Syndrome therapies

Aratana initiates pivotal field effectiveness study for AT-001

Spring Bank announces 3 presentations on SB 9200 at 27th ICAR

Coronary artery calcium score may help guide aspirin therapy, finds new research

Experimental antibody temporarily halts progression of neuroblastoma in children

Grace introduces ProVance Pre-packed Protein A Columns for mAb purification

AbbVie seeks marketing approval from EMA for all-oral, interferon-free therapy to treat HCV infection

Study: Anti-inflammatory compound interleukin-10 plays crucial role in regenerative, scarless healing

Single-cell genomics study confirms that immune cells produce steroids

Study: Pravastatin slows down growth of kidney cysts in children, young adults with ADPKD

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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