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Treating bacteria with silver compounds boosts efficacy of old antibiotics

Slipping bacteria some silver could give old antibiotics new life, scientists at the Wyss Institute for Biologically Inspired Engineering at Harvard University reported June 19 in Science Translational Medicine.

20 Jun 2013

Diapocynin antioxidant protects neurobehavioral function in mice with Parkinson's disease

Diapocynin, a synthetic molecule derived from a naturally occurring compound (apocynin), has been found to protect neurobehavioral function in mice with Parkinson's Disease symptoms by preventing deficits in motor coordination.

20 Jun 2013

Use of longer-acting anesthetic shows no difference in duration of hospitalization

The use of a less-expensive, longer-acting anesthetic (isoflurane) resulted in no difference in duration of hospitalization compared to the use of a more expensive, shorter-acting anesthetic (desflurane or sevoflurane), according to a study from the July issue of Anesthesiology.

20 Jun 2013

TSRI scientists receive NIH grant to create new drug for chronic lymphocytic leukemia

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded more than $1.4 million from the National Cancer Institute of the National Institutes of Health to create a potential new drug to attack the malignant cells that cause chronic lymphocytic leukemia (CLL), which is the most common leukemia in the Western world.

20 Jun 2013

High strength satin drugs do not increase risk of kidney injury among heart attack survivors

A higher strength of cholesterol-lowering drugs, or statins, did not increase the risk of kidney injury among heart attack survivors, according to preliminary research presented at the American Heart Association's Emerging Science Series Webinar.

20 Jun 2013

Viewpoints: Urgency has slipped away for 'grand bargain'; The need to scrutinize drug competition; Restore funding to 'Meals on Wheels'

It may seem paradoxical that Congress was willing to tackle a grand bargain when the deficit problem looked big and insoluble - but quickly lost interest as soon as the problem became more manageable. … But the reason isn't really mysterious. A grand bargain would have required both sides to swallow unpalatable compromises. It would have required Democrats to agree to cuts in future spending on Medicare and Social Security. Likewise, it would have required Republicans to accept increases in tax revenue (Doyle McManus, 6/19).

20 Jun 2013

FDA accepts DURECT's New Drug Application for POSIDUR

DURECT Corporation today announced that the New Drug Application for the investigational product POSIDUR (SABER-Bupivacaine) has been accepted by the U.S. Food and Drug Administration indicating that the application is sufficiently complete to permit a substantive review.

20 Jun 2013

Report: Improper prescription drug use drives up cost of care

Doctors and hospitals could save the U.S. $213 billion annually if they used prescription drugs more wisely, according to IMS health.

20 Jun 2013

New study shows that dietary fructose causes liver damage even without weight gain

The role of dietary fructose in the development of obesity and fatty liver diseases remains controversial, with previous studies indicating that the problems resulted from fructose and a diet too high in calories.

20 Jun 2013

Ibrutinib shows remarkable promise for treatment of mantle cell lymphoma

In a major international study led by researchers at The University of Texas MD Anderson Cancer Center, the targeted therapy ibrutinib continues to show remarkable promise for the treatment of relapsed or refractory mantle cell lymphoma (MCL).

20 Jun 2013

Loyola researcher to study role of Vitamin D in women with diabetes and depression

A Loyola University Chicago Niehoff School of Nursing researcher has received a four-year, $1.49 million grant to study whether Vitamin D can improve mood in women with diabetes who are depressed.

20 Jun 2013

Insulin degludec has reduced risk of recurrent hypoglycemia than insulin glargine

Insulin degludec (Tresiba), a new ultra-long-acting insulin, has a similar or reduced risk of recurrent hypoglycemia—low blood sugar—compared with the commercially available insulin glargine, a new meta-analysis study finds.

19 Jun 2013

Scientists discover new drug that cripples TB bug by dissolving its protective fatty coating

Most humans would like to shed their fatty exteriors, but tuberculosis (TB)-causing bacteria rely on theirs for survival. Scientists at the University of Medicine and Dentistry of New Jersey (UMDNJ)-New Jersey Medical School have now discovered a drug that cripples the TB bug by dissolving its protective fatty coating, a finding that could eventually be used to improve TB treatment in humans. The study has been posted online by Nature Chemical Biology.

19 Jun 2013

Rice scientists apply drug-design lessons to production of industrial minerals

Taking a page from computer-aided drug designers, Rice University researchers have developed a computational method that chemists can use to tailor the properties of zeolites, one of the world's most-used industrial minerals.

19 Jun 2013

High Court: Feds can sue pharmaceutical companies over deals to delay generic drug sales

The Supreme Court ruled Monday that the Federal Trade Commission can challenge name brand drug makers for potential antitrust violations.

19 Jun 2013

Spinal infection at contaminated drug injection site detected using contrast-enhanced MRI screening

Magnetic resonance imaging (MRI) at the site of injection of a contaminated lot of a steroid drug to treat symptoms such as back pain resulted in earlier identification of patients with probable or confirmed fungal spinal or paraspinal infection, allowing early initiation of medical and surgical treatment, according to a study in the June 19 issue of JAMA.

19 Jun 2013

OHSU analysis finds previous studies have overstated effectiveness of bone growth product used in spinal surgeries

An analysis by the Evidence-based Practice Center at Oregon Health & Science University has found that previously published clinical trial studies about a controversial bone growth product used in spinal surgeries overstated the product's effectiveness.

19 Jun 2013

NIH awards $12.7M to research groups to explore new treatments for patients in eight disease areas

The National Institutes of Health has awarded $12.7 million to match nine academic research groups with a selection of pharmaceutical industry compounds to explore new treatments for patients in eight disease areas, including Alzheimer's disease, Duchenne muscular dystrophy and schizophrenia.

19 Jun 2013

MMR booster does not result in worse JIA disease activity in children

Among children with juvenile idiopathic arthritis who had undergone primary immunization, the use of a measles-mumps-rubella booster compared with no booster did not result in worse JIA disease activity, according to a study in the June 19 issue of JAMA.

19 Jun 2013

Research shows that iodized salt used in bread not enough for pregnant women

Research from the University of Adelaide shows that iodized salt used in bread is not enough to provide healthy levels of iodine for pregnant women and their unborn children.

19 Jun 2013

Pharmaceutical News

Treating bacteria with silver compounds boosts efficacy of old antibiotics

Diapocynin antioxidant protects neurobehavioral function in mice with Parkinson's disease

Use of longer-acting anesthetic shows no difference in duration of hospitalization

TSRI scientists receive NIH grant to create new drug for chronic lymphocytic leukemia

High strength satin drugs do not increase risk of kidney injury among heart attack survivors

Viewpoints: Urgency has slipped away for 'grand bargain'; The need to scrutinize drug competition; Restore funding to 'Meals on Wheels'

FDA accepts DURECT's New Drug Application for POSIDUR

Report: Improper prescription drug use drives up cost of care

New study shows that dietary fructose causes liver damage even without weight gain

Ibrutinib shows remarkable promise for treatment of mantle cell lymphoma

Loyola researcher to study role of Vitamin D in women with diabetes and depression

Insulin degludec has reduced risk of recurrent hypoglycemia than insulin glargine

Scientists discover new drug that cripples TB bug by dissolving its protective fatty coating

Rice scientists apply drug-design lessons to production of industrial minerals

High Court: Feds can sue pharmaceutical companies over deals to delay generic drug sales

Spinal infection at contaminated drug injection site detected using contrast-enhanced MRI screening

OHSU analysis finds previous studies have overstated effectiveness of bone growth product used in spinal surgeries

NIH awards $12.7M to research groups to explore new treatments for patients in eight disease areas

MMR booster does not result in worse JIA disease activity in children

Research shows that iodized salt used in bread not enough for pregnant women

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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