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Sirolimus effective in treating children with Pretzel syndrome, new study reports

With a better understanding of underlying mechanisms that cause a rare neurodevelopmental disorder in the Old Order Mennonite population, referred to as Pretzel syndrome, a new study reports that five children were successfully treated with a drug that modifies the disease process, minimizing seizures and improving receptive language.

25 Apr 2013

University of Guelph researchers develop carbohydrate-based vaccine against gut bug

A first-ever vaccine created by University of Guelph researchers for gut bacteria common in autistic children may also help control some autism symptoms.

25 Apr 2013

Promising development for women with triple-negative breast cancer

Tamoxifen is a time-honored breast cancer drug used to treat millions of women with early-stage and less-aggressive disease, and now a University of Rochester Medical Center team has shown how to exploit tamoxifen's secondary activities so that it might work on more aggressive breast cancer.

24 Apr 2013

South Africa aims to close drug patent loophole that allows for 'ever-greening'

"South Africa plans to overhaul its intellectual property laws to improve access to cheaper medicines by making it harder for pharmaceutical firms to register and roll-over patents for drugs, a senior official said on Monday," Reuters reports.

24 Apr 2013

Political, public health leaders convene in Gulf for Global Vaccine Summit

"Political and public health leaders meeting in the Gulf this week will back a $5.5 billion plan to eradicate polio within five years, despite repeated setbacks including a recent spate of assassinations of health workers giving vaccines," the Financial Times reports.

24 Apr 2013

Opinion pieces address polio eradication goal to be discussed at Global Vaccine Summit

Public and private sector representatives will meet this week in Abu Dhabi at the Global Vaccine Summit, hosted by His Highness General Sheikh Mohamed bin Zayed bin Sultan Al Nahyan, Crown Prince of Abu Dhabi, in partnership with U.N. Secretary-General Ban Ki-moon and Bill Gates, co-chair of the Bill & Melinda Gates Foundation.

24 Apr 2013

Research project to identify mechanisms underlying effects of cancer drug interferon-α

The immune system plays a decisive role in the fight against tumor cells. However, when tumor cells themselves prevent activation of the immune system, the immune system fails to destroy cancer cells.

24 Apr 2013

Blog posts address goal of universal immunization

World Immunization Week (April 21-28) aims to raise awareness that immunizations avert two to three million deaths annually, but an estimated 22 million infants are not fully immunized with routine vaccines.

24 Apr 2013

Bill Gates reflects on Global Vaccine Summit in foundation blog

"This week I'm going to Abu Dhabi to attend the Global Vaccine Summit to celebrate the tremendous progress the world has made in ending polio and immunizing children," Bill Gates, co-chair of the Bill & Melinda Gates Foundation, writes in the foundation's "Impatient Optimists" blog.

24 Apr 2013

Metals in medicines webinar to be presented by SPECTRO

Arsenic has many facets. Arsenic compounds are not only deadly poisons to which many crowned heads fell victim in previous eras, but in small doses arsenic was also given to horses because it promotes appetite and the growth of hair. In this way, horse traders could revitalize old nags and sell them for more money.

24 Apr 2013

FDA grants orphan-drug designation to XEN402 for treatment of pain associated with EM

Teva Pharmaceutical Industries Ltd. and Xenon Pharmaceuticals Inc. announced today that the US Food and Drug Administration has granted orphan-drug designation to the investigational drug XEN402 being developed for the treatment of pain associated with erythromelalgia.

24 Apr 2013

Sucampo's supplemental new drug application for AMITIZA gets FDA approval

Sucampo Pharmaceuticals, Inc. and Takeda Pharmaceuticals U.S.A., Inc. announced today that the United States Food and Drug Administration has approved Sucampo's supplemental new drug application for AMITIZA (lubiprostone) (24 mcg twice daily) as the first and only oral medication for the treatment of opioid-induced constipation in adult patients with chronic, non-cancer pain.

24 Apr 2013

BD receives FDA approval for second prefilled injectable drug

BD Rx Inc., a wholly-owned subsidiary of leading global medical technology company BD, announced today that the U.S. Food and Drug Administration has approved the second drug to be offered in the recently launched BD Simplist line of ready-to-administer prefilled generic injectables.

From BD (Becton, Dickinson and Company) 24 Apr 2013

Maternal use of valproate during pregnancy increases risk of autism in offspring

Maternal use of valproate (a drug used for the treatment of epilepsy and other neuropsychological disorders) during pregnancy was associated with a significantly increased risk of autism in offspring, according to a study in the April 24 issue of JAMA.

24 Apr 2013

Researchers uncover potential new way to fight obesity-related illness

A potential new way to fight obesity-related illness has been uncovered, thanks to serendipitous research led by investigators at the Case Western Reserve University School of Medicine.

24 Apr 2013

Psychedelics continue to be widely used in US, researchers say

In their article "Over 30 million psychedelic users in the United States", Teri S Krebs and P-l--rjan Johansen from the Department of Neuroscience at Norwegian University of Science and Technology, use data from a randomly-selected sample of over 57,000 individuals surveyed for the 2010 National Survey on Drug Use and Health, to estimate lifetime prevalence of psychedelic use.

24 Apr 2013

Therapy originally conceived for cancer could hold promise for weight loss, say researchers

Researchers have long known that cancerous tumors grow collections of abnormal blood cells, the fuel that feeds this disease and keeps it growing. Now, new evidence in an animal model suggests that blood vessels in the fat tissue of obese individuals could provide the same purpose-and could provide the key to a new way for people to lose weight.

24 Apr 2013

Study suggests lung cancer patients with HER2 mutations may benefit from anti-HER2 drugs

New results from a retrospective study conducted in Europe suggest that anti-HER2 treatments, like the widely used breast cancer agent trastuzumab (Herceptin), have anti-cancer effects in a small subset of patients with advanced non-small cell lung cancer (NSCLC) harboring specific HER2 protein mutations.

23 Apr 2013

Study suggests specific form of vitamin E supplement improves function of blood vessels

Taking a specific form of a vitamin E supplement can accelerate the health benefits that occur when people quit smoking, new research suggests.

23 Apr 2013

1 in 4 teens misused or abused a prescription drug at least once in their lifetime

New, nationally projectable survey results released today by The Partnership at Drugfree.org and MetLife Foundation confirmed that one in four teens has misused or abused a prescription (Rx) drug at least once in their lifetime - a 33 percent increase over the past five years.

23 Apr 2013

Pharmaceutical News

Sirolimus effective in treating children with Pretzel syndrome, new study reports

University of Guelph researchers develop carbohydrate-based vaccine against gut bug

Promising development for women with triple-negative breast cancer

South Africa aims to close drug patent loophole that allows for 'ever-greening'

Political, public health leaders convene in Gulf for Global Vaccine Summit

Opinion pieces address polio eradication goal to be discussed at Global Vaccine Summit

Research project to identify mechanisms underlying effects of cancer drug interferon-α

Blog posts address goal of universal immunization

Bill Gates reflects on Global Vaccine Summit in foundation blog

Metals in medicines webinar to be presented by SPECTRO

FDA grants orphan-drug designation to XEN402 for treatment of pain associated with EM

Sucampo's supplemental new drug application for AMITIZA gets FDA approval

BD receives FDA approval for second prefilled injectable drug

Maternal use of valproate during pregnancy increases risk of autism in offspring

Researchers uncover potential new way to fight obesity-related illness

Psychedelics continue to be widely used in US, researchers say

Therapy originally conceived for cancer could hold promise for weight loss, say researchers

Study suggests lung cancer patients with HER2 mutations may benefit from anti-HER2 drugs

Study suggests specific form of vitamin E supplement improves function of blood vessels

1 in 4 teens misused or abused a prescription drug at least once in their lifetime

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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