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Study: Regional anesthesia associated with with fewer postoperative complications in orthopedic surgery patients

A study published in the May issue of Anesthesiology discovered that spinal or epidural anesthesia, types of regional anesthesia that numb patients from the abdomen to the toes, were associated with fewer postoperative complications and death than general anesthesia in patients undergoing primary hip or knee replacement.

25 Apr 2013

New antimicrobial agents do not rely on traditional antibiotics

In an advance toward coping with bacteria that shrug off existing antibiotics and sterilization methods, scientists are reporting development of a new family of selective antimicrobial agents that do not rely on traditional antibiotics.

25 Apr 2013

Cardiac risk patients treated with beta-blockers have lower rates of mortality

Patients at elevated cardiac risk who were treated with beta-blockers on the day of or following noncardiac, nonvascular surgery had significantly lower rates of 30-day mortality and cardiac illness, according to a study in the April 24 issue of JAMA.

25 Apr 2013

ORAEs increase costs of care, hospital stays and risks of readmission and mortality, research finds

Pacira Pharmaceuticals, Inc. today announced the publication of findings from a retrospective analysis of more than 37,000 patients who underwent common inpatient surgeries at a large, 26-hospital healthcare system and received opioids for postsurgical pain management.

25 Apr 2013

Study: Melatonin delays symptom onset, reduces mortality in mouse model of ALS

Melatonin injections delayed symptom onset and reduced mortality in a mouse model of the neurodegenerative condition amyotrophic lateral sclerosis, or Lou Gehrig's disease, according to a new study by researchers at the University of Pittsburgh School of Medicine.

25 Apr 2013

Donations made, agreements signed to fight polio in advance of Global Vaccine Summit

Hundreds of international health experts and leaders from the public and private sectors are gathered in Abu Dhabi Wednesday for the beginning of the first Global Vaccine Summit, which "is expected to place special emphasis on polio eradication," Gulf News reports (Zaman, 4/23).

25 Apr 2013

MCCIR scientists use video imaging to investigate effectiveness of rituximab in killing cancerous B cells

Scientists from the Manchester Collaborative Centre for Inflammation Research have discovered why a particular cancer drug is so effective at killing cells.

From The University of Manchester 25 Apr 2013

U.S. files suit against Novartis in alleged kickback scheme

The suit accuses the drugmaker of giving pharmacies discounts and rebates to promote the use of the drug Myfortic.

25 Apr 2013

Omega-3 polyunsaturated fatty acids associated with lower risk of heart failure mortality in adults

Omega-3 polyunsaturated fatty acids, namely DHA and EPA found in fatty fish, are associated with lower risk of heart failure mortality in adults with chronic heart failure or who have experienced a heart attack.

25 Apr 2013

FDA announces public-private partnership to identify counterfeit anti-malarial medicines with CD-3

The U.S. Food and Drug Administration today announced a public-private partnership to help identify counterfeit or substandard anti-malarial medicines, including falsified products, with the deployment of the FDA-developed Counterfeit Detection Device, called CD-3.

25 Apr 2013

WHO highlights threat of antimalarial drug resistance in Greater Mekong subregion

On World Malaria Day, 25 April, WHO recognizes significant accomplishments in preventing and controlling malaria, including in high-burden countries in sub-Saharan Africa, but highlights the threat of antimalarial drug resistance in south-east Asia's Greater Mekong subregion, where an emergency response is now being launched.

25 Apr 2013

Janssen submits Marketing Authorization Application to EMA for simeprevir approval

Medivir AB today announces that Janssen-Cilag International NV today has submitted a Marketing Authorization Application to the European Medicines Agency seeking approval for simeprevir (TMC435).

25 Apr 2013

FDA designates Merck's lambrolizumab as Breakthrough Therapy for advanced melanoma

Merck (NYSE: MRK), known as MSD outside the United States and Canada, announced today that the U.S. Food and Drug Administration has designated lambrolizumab (MK-3475) as a Breakthrough Therapy for the treatment of patients with advanced melanoma.

25 Apr 2013

Sirolimus effective in treating children with Pretzel syndrome, new study reports

With a better understanding of underlying mechanisms that cause a rare neurodevelopmental disorder in the Old Order Mennonite population, referred to as Pretzel syndrome, a new study reports that five children were successfully treated with a drug that modifies the disease process, minimizing seizures and improving receptive language.

25 Apr 2013

University of Guelph researchers develop carbohydrate-based vaccine against gut bug

A first-ever vaccine created by University of Guelph researchers for gut bacteria common in autistic children may also help control some autism symptoms.

25 Apr 2013

Promising development for women with triple-negative breast cancer

Tamoxifen is a time-honored breast cancer drug used to treat millions of women with early-stage and less-aggressive disease, and now a University of Rochester Medical Center team has shown how to exploit tamoxifen's secondary activities so that it might work on more aggressive breast cancer.

24 Apr 2013

South Africa aims to close drug patent loophole that allows for 'ever-greening'

"South Africa plans to overhaul its intellectual property laws to improve access to cheaper medicines by making it harder for pharmaceutical firms to register and roll-over patents for drugs, a senior official said on Monday," Reuters reports.

24 Apr 2013

Political, public health leaders convene in Gulf for Global Vaccine Summit

"Political and public health leaders meeting in the Gulf this week will back a $5.5 billion plan to eradicate polio within five years, despite repeated setbacks including a recent spate of assassinations of health workers giving vaccines," the Financial Times reports.

24 Apr 2013

Opinion pieces address polio eradication goal to be discussed at Global Vaccine Summit

Public and private sector representatives will meet this week in Abu Dhabi at the Global Vaccine Summit, hosted by His Highness General Sheikh Mohamed bin Zayed bin Sultan Al Nahyan, Crown Prince of Abu Dhabi, in partnership with U.N. Secretary-General Ban Ki-moon and Bill Gates, co-chair of the Bill & Melinda Gates Foundation.

24 Apr 2013

Research project to identify mechanisms underlying effects of cancer drug interferon-α

The immune system plays a decisive role in the fight against tumor cells. However, when tumor cells themselves prevent activation of the immune system, the immune system fails to destroy cancer cells.

24 Apr 2013

Pharmaceutical News

Study: Regional anesthesia associated with with fewer postoperative complications in orthopedic surgery patients

New antimicrobial agents do not rely on traditional antibiotics

Cardiac risk patients treated with beta-blockers have lower rates of mortality

ORAEs increase costs of care, hospital stays and risks of readmission and mortality, research finds

Study: Melatonin delays symptom onset, reduces mortality in mouse model of ALS

Donations made, agreements signed to fight polio in advance of Global Vaccine Summit

MCCIR scientists use video imaging to investigate effectiveness of rituximab in killing cancerous B cells

U.S. files suit against Novartis in alleged kickback scheme

Omega-3 polyunsaturated fatty acids associated with lower risk of heart failure mortality in adults

FDA announces public-private partnership to identify counterfeit anti-malarial medicines with CD-3

WHO highlights threat of antimalarial drug resistance in Greater Mekong subregion

Janssen submits Marketing Authorization Application to EMA for simeprevir approval

FDA designates Merck's lambrolizumab as Breakthrough Therapy for advanced melanoma

Sirolimus effective in treating children with Pretzel syndrome, new study reports

University of Guelph researchers develop carbohydrate-based vaccine against gut bug

Promising development for women with triple-negative breast cancer

South Africa aims to close drug patent loophole that allows for 'ever-greening'

Political, public health leaders convene in Gulf for Global Vaccine Summit

Opinion pieces address polio eradication goal to be discussed at Global Vaccine Summit

Research project to identify mechanisms underlying effects of cancer drug interferon-α

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

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