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First Edition: March 25, 2013

Today's headlines include reports about the continuing outlook for progress on the federal budget as well as a variety of stories related to the health law's implementation.

25 Mar 2013

Actavis settles patent litigation with AstraZeneca over generic version of Crestor

Actavis, Inc., a leading specialty pharmaceutical company, today announced that is has reached a settlement agreement with AstraZeneca resolving outstanding patent litigation related to Actavis' generic version of rosuvastatin calcium 5, 10, 20 and 40 mg tablets, the generic version of Crestor tablets, as well as Actavis' rosuvastatin zinc alternate salt product.

25 Mar 2013

Study shows why certain drugs that interact with serotonin receptors have harmful effects

A team including scientists from The Scripps Research Institute (TSRI), the University of North Carolina at Chapel Hill and the Chinese Academy of Sciences has determined and analyzed the high-resolution atomic structures of two kinds of human serotonin receptor.

25 Mar 2013

Anti-inflammatory drug naproxen may exhibit antiviral activity against influenza A virus

The over-the-counter anti-inflammatory drug naproxen may also exhibit antiviral activity against influenza A virus, according to a team of French scientists. The finding, the result of a structure-based investigation, is published online ahead of print in the journal Antimicrobial Agents and Chemotherapy.

25 Mar 2013

Parkinson's Disease drug can help reverse age-related impairments in decision making: Study

A drug widely used to treat Parkinson's Disease can help to reverse age-related impairments in decision making in some older people, a study from researchers at the Wellcome Trust Centre for Neuroimaging has shown.

25 Mar 2013

Botulism Antitoxin Heptavalent gets FDA approval for patients showing signs of botulism

The U.S. Food and Drug Administration announced today that it has approved Botulism Antitoxin Heptavalent (A, B, C, D, E, F, G)-(Equine) to treat patients showing signs of botulism following documented or suspected exposure to botulinum neurotoxin.

25 Mar 2013

Epizyme receives patent for drug candidate for genetically defined type of non-Hodgkin lymphomas

Epizyme, Inc., a clinical stage biopharmaceutical company creating innovative personalized therapeutics for patients with genetically defined cancers, announced today that it has received a Notice of Issuance from the U.S. Patent and Trademark Office for its patent application entitled "ARYL-OR HETEROARYL-SUBSTITUTED BENZENE COMPOUNDS", U.S. Patent No.: 8,410,088.

24 Mar 2013

TOBI Podhaler receives FDA approval for cystic fibrosis patients with Pseudomonas aeruginosa

The U.S. Food and Drug Administration today approved TOBI Podhaler (tobramycin inhalation powder) for the management of cystic fibrosis patients with Pseudomonas aeruginosa, a bacterium that causes lung infections.

24 Mar 2013

Effectiveness of candidate malaria vaccine decreases over time, study shows

"The effectiveness of an experimental malaria vaccine developed by GlaxoSmithKline wanes over time, with the shot protecting only 16.8 percent of children over four years, according to trial data," Reuters reports.

22 Mar 2013

Researchers develop new approach for HIV vaccine development

Decades of research and three large-scale clinical trials have so far failed to yield an effective HIV vaccine, in large part because the virus evolves so rapidly that it can evade any vaccine-induced immune response.

22 Mar 2013

New hope for treating, preventing malaria

Scientists at Oregon Health & Science University and the Portland VA Medical Center have developed a drug that may represent one of the world's best hopes for treating and preventing malaria - a disease that kills more than one million people each year.

22 Mar 2013

Findings provide structural basis for development of drugs to fight enterovirus 71 infection

New research findings may help scientists design drugs to treat a virus infection that causes potentially fatal brain swelling and paralysis in children.

22 Mar 2013

Common test may overestimate exposure to mercury vapor from dental amalgams

A common test used to determine mercury exposure from dental amalgam fillings may significantly overestimate the amount of the toxic metal released from fillings, according to University of Michigan researchers.

21 Mar 2013

First Edition: March 21, 2013

Today's headlines include various reports about what the public knows -- and doesn't know -- about the health law.

21 Mar 2013

Alarming report on persistent side effects of antidepressant drugs published online

An alarming report from patient online websites on persistent side effects of antidepressant drugs has been published in one of the last issue of Psychotherapy and Psychosomatics by investigators from the University of Bologna and North America.

21 Mar 2013

Supreme Court considering generic drugmaker safety liability

The Supreme Court is weighing if generic drugmakers can be sued over the safety of their drugs or if federal regulators' safety approval is enough to block all such legal challenges.

21 Mar 2013

Dotarem gets FDA approval for use in patients undergoing CNS MRI

The U.S. Food and Drug Administration today approved Dotarem (gadoterate meglumine) for use in magnetic resonance imaging of the brain, spine and associated tissues of patients ages 2 years and older.

21 Mar 2013

New class of anti-malarial compounds discovered

A group of researchers from 16 institutions around the world has identified a new class of anti-malarial compounds that target multiple stages of the malaria parasite's life cycle.

21 Mar 2013

Researchers develop promising drug candidate to treat psoriasis

Ben-Gurion University of the Negev researchers, in collaboration with Teva Pharmaceutical Industries Ltd., have developed a promising drug candidate to treat psoriasis.

21 Mar 2013

Estrogen provides long-term relief for post-menopausal women suffering from joint pain

Post-menopausal women, who often suffer from joint pain, could find some long-term relief by taking estrogen-only medication, according to a new study based on the Women's Health Initiative (WHI) that was released online today by the journal, Menopause.

21 Mar 2013

Pharmaceutical News

First Edition: March 25, 2013

Actavis settles patent litigation with AstraZeneca over generic version of Crestor

Study shows why certain drugs that interact with serotonin receptors have harmful effects

Anti-inflammatory drug naproxen may exhibit antiviral activity against influenza A virus

Parkinson's Disease drug can help reverse age-related impairments in decision making: Study

Botulism Antitoxin Heptavalent gets FDA approval for patients showing signs of botulism

Epizyme receives patent for drug candidate for genetically defined type of non-Hodgkin lymphomas

TOBI Podhaler receives FDA approval for cystic fibrosis patients with Pseudomonas aeruginosa

Effectiveness of candidate malaria vaccine decreases over time, study shows

Researchers develop new approach for HIV vaccine development

New hope for treating, preventing malaria

Findings provide structural basis for development of drugs to fight enterovirus 71 infection

Common test may overestimate exposure to mercury vapor from dental amalgams

First Edition: March 21, 2013

Alarming report on persistent side effects of antidepressant drugs published online

Supreme Court considering generic drugmaker safety liability

Dotarem gets FDA approval for use in patients undergoing CNS MRI

New class of anti-malarial compounds discovered

Researchers develop promising drug candidate to treat psoriasis

Estrogen provides long-term relief for post-menopausal women suffering from joint pain

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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