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Scientists produce monoclonal antibody in tobacco plants that neutralizes rabies viruses

Smoking tobacco might be bad for your health, but a genetically altered version of the plant might provide a relatively inexpensive cure for the deadly rabies virus. In a new research report appearing in The FASEB Journal, scientists produced a monoclonal antibody in transgenic tobacco plants that was shown to neutralize the rabies virus.

2 Feb 2013

Modafinil may help some people to reduce drinking by improving their impulse control

Poor impulse control contributes to one's inability to control the consumption of rewarding substances, like food, alcohol, and other drugs. This can lead to the development of addiction. FDA-approved medications for alcoholism, like naltrexone (Revia) and disulfiram (Antabuse), are thought to reduce alcohol consumption by curbing cravings and creating unpleasant reactions to alcohol, effects which reduce the desire to drink alcohol.

2 Feb 2013

New drug to prevent early stages of Alzheimer's could enter clinical trials soon

A new drug to prevent the early stages of Alzheimer's disease could enter clinical trials in a few years' time according to scientists.

2 Feb 2013

Quantum dots can rapidly deliver calcitriol to targeted tumor sites for treatment of IBC

The shortened daylight of a Maine winter may make for long, dark nights - but it has shone a light on a novel experimental approach to fighting inflammatory breast cancer (IBC), an especially deadly form of breast cancer.

2 Feb 2013

Low testosterone levels occur more often among men on long-acting opioids

Low testosterone levels occur five times more often among men who take long-acting instead of short-acting opioids for chronic pain, according to a new Kaiser Permanente study published in The Clinical Journal of Pain.

2 Feb 2013

FDA announces federal judge approval of Ben Venue consent decree

The U.S. Food and Drug Administration announced today that a federal judge has approved a consent decree of permanent injunction against Ben Venue Laboratories, Inc., and three of its corporate officers for failing to comply with current good manufacturing practice requirements as required by federal law.

2 Feb 2013

Inadequate health literacy among Latinos linked with poor understanding of antibiotic use

In the first study of its kind, researchers at the Columbia University School of Nursing have established that poor health literacy among Latino parents is associated with a poor understanding of the proper use antibiotics, particularly for upper respiratory infections (URIs), which can lead to an increase in antimicrobial resistance.

2 Feb 2013

DHEA-S may prevent neurocognitive impairment that affects AIDS patients

A team of scientists from Canada, Thailand and Morocco have found that DHEA-S may prevent neurocognitive impairment that affects a significant percentage of AIDS patients. In a report appearing in the February 2013 issue of The FASEB Journal, they describe how a network of steroid molecules found in the brain, termed "neurosteroids," is disrupted during HIV infection leading to brain damage.

2 Feb 2013

University of Kentucky professor to continue research into ruthenium-based cancer drugs

University of Kentucky assistant professor of chemistry Edith "Phoebe" Glazer has received an American Cancer Society Research Scholar Grant for $715,000 over four years to continue her research into ruthenium-based cancer drugs. These compounds are less toxic to healthy cells than a similar and widely used inorganic drug.

1 Feb 2013

Hyperion Therapeutics receives FDA approval for Ravicti to treat urea cycle disorders

The U.S. Food and Drug Administration today approved Ravicti (glycerol phenylbutyrate) for the chronic management of some urea cycle disorders (UCDs) in patients ages 2 years and older.

1 Feb 2013

Pharmacuetical companies eye orphan drugs as new revenue source

Drug companies are fond of saying that every patient counts, but in the world of orphan diseases, entire business plans are built around the idea. ... Development of these drugs is increasingly attractive to pharmaceutical companies, which are searching for new sources of revenue as sales of more traditional, mass-market drugs have been lost to generic competition.

1 Feb 2013

Book reviews psilocybin's potential in alleviating psychological distress in cancer patients

Improvements in the diagnosis and treatment of cancers in recent years have led to a marked increase in patients' physical survival rates. While doctors can treat the physical disease, what is not well understood is how best to address the psychological needs of patients with cancer.

1 Feb 2013

Seattle Genetics receives Health Canada approval for ADCETRIS to treat sALCL, Hodgkin lymphoma

Seattle Genetics, Inc. today announced that Health Canada has issued a Notice of Compliance with conditions (NOC/c), authorizing marketing of ADCETRIS for two lymphoma indications.

1 Feb 2013

Perrigo introduces generic Olux-E Foam, 0.05%

Perrigo Company today announced that it has launched clobetasol emulsion propionate foam, 0.05%, the generic equivalent of Olux -E Foam, 0.05%.

1 Feb 2013

Study supports hypothesis that disulfiram reduces drug consumption by blocking DβH

Disulfiram was the first medication approved for the treatment of alcoholism over 50 years ago. It works, at least in part, by preventing the metabolism of an alcohol by-product, acetaldehyde. High levels of acetaldehyde in the body quickly cause unpleasant symptoms, including nausea, vomiting, headache, and accelerated heart rate. Thus, disulfiram provides a very strong incentive to avoid drinking.

1 Feb 2013

FDA approves Biotest's BIVIGAM to treat Primary Humoral Immunodeficiency

Biotest Pharmaceuticals Corporation (BPC), a wholly owned U.S. subsidiary of Biotest AG, recently announced the U.S. Food and Drug Administration's (FDA) approval of BIVIGAM, its new intravenous immune globulin, for the treatment of patients with Primary Humoral Immunodeficiency (PI).

31 Jan 2013

Resonance Health receives FDA marketing authorization for FerriScan R2-MRI device

The U.S. Food and Drug Administration recently announced the authorization of FerriScan R2-MRI to be marketed as an imaging companion diagnostic device for the safe and effective use of Exjade in patients with non-transfusion-dependent thalassemia.

31 Jan 2013

Delaware District Court rules in favor of Pfizer in RAPAMUNE patent case

Pfizer Inc. said today that the United States District Court for the District of Delaware ruled that Pfizer's patent covering a method for using sirolimus, the active ingredient in RAPAMUNE®, for the inhibition of organ transplant rejection is valid and infringed.

31 Jan 2013

Northeast Ohio Medical University, CEL-SCI produce new investigational breast cancer vaccine

CEL-SCI Corporation announced that its longstanding collaboration with Northeast Ohio Medical University has produced a new investigational breast cancer vaccine which prevents and treats a HER-2/neu expressing breast cancer tumor in a mouse model of the disease.

31 Jan 2013

GSU associate professor receives federal grant to bolster flu vaccine research

Sang-Moo Kang, associate professor at Georgia State University's Center for Inflammation, Immunity and Infection, has received a federal five-year, $3.4 million grant to bolster research that will lead to better flu vaccines and vaccines against respiratory syncytial virus (RSV), a disease for which there is no immunization.

31 Jan 2013

Pharmaceutical News

Scientists produce monoclonal antibody in tobacco plants that neutralizes rabies viruses

Modafinil may help some people to reduce drinking by improving their impulse control

New drug to prevent early stages of Alzheimer's could enter clinical trials soon

Quantum dots can rapidly deliver calcitriol to targeted tumor sites for treatment of IBC

Low testosterone levels occur more often among men on long-acting opioids

FDA announces federal judge approval of Ben Venue consent decree

Inadequate health literacy among Latinos linked with poor understanding of antibiotic use

DHEA-S may prevent neurocognitive impairment that affects AIDS patients

University of Kentucky professor to continue research into ruthenium-based cancer drugs

Hyperion Therapeutics receives FDA approval for Ravicti to treat urea cycle disorders

Pharmacuetical companies eye orphan drugs as new revenue source

Book reviews psilocybin's potential in alleviating psychological distress in cancer patients

Seattle Genetics receives Health Canada approval for ADCETRIS to treat sALCL, Hodgkin lymphoma

Perrigo introduces generic Olux-E Foam, 0.05%

Study supports hypothesis that disulfiram reduces drug consumption by blocking DβH

FDA approves Biotest's BIVIGAM to treat Primary Humoral Immunodeficiency

Resonance Health receives FDA marketing authorization for FerriScan R2-MRI device

Delaware District Court rules in favor of Pfizer in RAPAMUNE patent case

Northeast Ohio Medical University, CEL-SCI produce new investigational breast cancer vaccine

GSU associate professor receives federal grant to bolster flu vaccine research

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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