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UPV/EHU team uses lipid nanoparticles to develop new formulations for drug delivery

At the Faculty of Pharmacy of the Basque Public University (UPV/EHU) the Pharmacokinetics, Nanotechnology and Gene Therapy research team is using nanotechnology to develop new formulations that can be applied to drugs and gene therapy.

1 Mar 2013

Steroids may reduce length of hospital stay in patients with pneumonia

Patients with pneumonia may spend fewer days in the hospital if they are given steroids along with antibiotics and supportive care. That's the finding of a Mayo Clinic analysis of eight randomized-controlled clinical trials involving more than 1,100 patients.

1 Mar 2013

Combined spinal-epidural technique offers faster and better-quality analgesia during early labor

During the first stage of labor, a combined spinal-epidural (CSE) technique offers faster and better-quality analgesia (pain relief) compared to traditional epidural analgesia, according to a report in the March issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

28 Feb 2013

Annual deaths related to heroin and morphine continue to drop in the UK

Annual deaths related to heroin and morphine are continuing to drop significantly, falling from 41 per cent of total drug-related deaths in the UK in 2010 to 32 per cent in 2011. Meanwhile, deaths from 'legal highs' - some of which have now been banned - remained steady following a large increase in the previous year.

28 Feb 2013

Blocking aPKC activity can stop growth of transplanted skin tumors resistant to vismodegib

Hailed as a major step forward in the effort to develop targeted cancer therapies, a recently approved drug for the most common type of skin cancer has been a mixed blessing for patients. Although the initial response is usually dramatic, the tumors often recur as the cancer becomes resistant to treatment.

28 Feb 2013

Engineering chemotherapy drugs' shape increases their ability to target and inhibit cancer cells

Bioengineering researchers at University of California, Santa Barbara have found that changing the shape of chemotherapy drug nanoparticles from spherical to rod-shaped made them up to 10,000 times more effective at specifically targeting and delivering anti-cancer drugs to breast cancer cells.

28 Feb 2013

State roundup: Health care industry calls drug testing bill in N.H. 'vague'

Representatives from the health care industry said Tuesday they have a vested interest in stopping employees from stealing controlled substances but a bill being considered by New Hampshire lawmakers to drug test their workers is too vague. The proposal is part of the legislative response to a recent scandal at Exeter Hospital, where an employee allegedly stole drugs and replaced them with Hepatitis C infected syringes later used on patients.

28 Feb 2013

UNAIDS, UNDP release issue brief on TRIPS transition period extensions for LDCs

"The Joint United Nations Programme on HIV/AIDS (UNAIDS) and the United Nations Development Programme (UNDP) today launched a new issue brief", titled "TRIPS transition period extensions for least-developed countries [LDCs]," a UNAIDS press release reports.

28 Feb 2013

Medical Adhesives for Reusable or Disposable Medical Devices

An interview with Robert Michaels, discussing the major challenges faced by engineers designing medical devices and the development of new medical adhesives.

From Master Bond Inc. 28 Feb 2013

Mutant HSP70i protein may offer potent treatment opportunities for vitiligo

Loyola University Chicago Stritch School of Medicine researchers have developed a genetically modified protein that dramatically reverses the skin disorder vitiligo in mice, and has similar effects on immune responses in human skin tissue samples.

28 Feb 2013

Reintroducing normal microbial diversity can eliminate VRE from intestinal tracts

Too much antibiotic can decimate the normal intestinal microbiota, which may never recover its former diversity. That, in turn, renders the GI tract vulnerable to being colonized by pathogens. Now researchers from Memorial Sloan-Kettering Cancer Center, New York, NY, and Centro Superior de Investigaci-n en Salud P-blica, Valencia, Spain, show that reintroducing normal microbial diversity largely eliminated vancomycin-resistant enterococci (VRE) from the intestinal tracts of mice..

28 Feb 2013

Efforts to copy biotech drugs face delays, obstacles

Much anticipated knockoff versions of costly biotech medicines are facing delays and obstacles that could cost patients and health systems billions in missed savings.

28 Feb 2013

Excess of vitamin D during pregnancy can increase risk of food allergy in children

Pregnant women should avoid taking vitamin D supplements. Substitution appears to raise the risk of children developing a food allergy after birth.

28 Feb 2013

Study designs and tests 60 compounds for their ability to kill human cancer cells

Inspired by a chemical that fungi secrete to defend their territory, MIT chemists have synthesized and tested several dozen compounds that may hold promise as potential cancer drugs.

28 Feb 2013

Novel immunotherapy could potentially work like a vaccine against metastatic cancers

Preclinical, laboratory studies suggest a novel immunotherapy could potentially work like a vaccine against metastatic cancers, according to scientists at Virginia Commonwealth University Massey Cancer Center.

28 Feb 2013

MenB bacterium uses Adhesin Complex Protein to stick to human cells

Scientists at the University of Southampton have taken a significant and important step in keeping people safe from the most common form of meningitis in the UK.

28 Feb 2013

Anesthetics during breast cancer surgery may affect development of chronic pain

In women with breast cancer, the choice of anesthetic used for mastectomy may affect the risk of developing long-term pain after surgery, according to a study in the March issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

28 Feb 2013

National Birth Defects Prevention Network honors BU researcher with Godfrey P. Oakley, Jr., Award

Allen A. Mitchell, MD, a professor of public health (epidemiology) and professor of pediatrics at the Boston University Schools of Public Health and Medicine, recently received the Godfrey P. Oakley, Jr., Award at the annual meeting of the National Birth Defects Prevention Network. Mitchell, who is also the director of Boston University's Slone Epidemiology Center (SEC), was recognized for his significant lifetime contributions to the field of birth defects.

28 Feb 2013

Herceptin may have greater role in treating HER2-negative breast cancer

New research from the University of Michigan Comprehensive Cancer Center finds that the protein HER2 plays a role even in breast cancers that would traditionally be categorized as HER2-negative - and that the drug Herceptin, which targets HER2, may have an even greater role for treating breast cancer and preventing its spread.

28 Feb 2013

Resolve Therapeutics, Takeda partner to develop compounds for treatment of lupus

Takeda Pharmaceutical Company Limited and Resolve Therapeutics, LLC today jointly announced that they have entered into a partnership to develop compounds for the treatment of lupus (also known as Systemic Lupus Erythematosus, or SLE) and other autoimmune diseases.

27 Feb 2013

Pharmaceutical News

UPV/EHU team uses lipid nanoparticles to develop new formulations for drug delivery

Steroids may reduce length of hospital stay in patients with pneumonia

Combined spinal-epidural technique offers faster and better-quality analgesia during early labor

Annual deaths related to heroin and morphine continue to drop in the UK

Blocking aPKC activity can stop growth of transplanted skin tumors resistant to vismodegib

Engineering chemotherapy drugs' shape increases their ability to target and inhibit cancer cells

State roundup: Health care industry calls drug testing bill in N.H. 'vague'

UNAIDS, UNDP release issue brief on TRIPS transition period extensions for LDCs

Medical Adhesives for Reusable or Disposable Medical Devices

Mutant HSP70i protein may offer potent treatment opportunities for vitiligo

Reintroducing normal microbial diversity can eliminate VRE from intestinal tracts

Efforts to copy biotech drugs face delays, obstacles

Excess of vitamin D during pregnancy can increase risk of food allergy in children

Study designs and tests 60 compounds for their ability to kill human cancer cells

Novel immunotherapy could potentially work like a vaccine against metastatic cancers

MenB bacterium uses Adhesin Complex Protein to stick to human cells

Anesthetics during breast cancer surgery may affect development of chronic pain

National Birth Defects Prevention Network honors BU researcher with Godfrey P. Oakley, Jr., Award

Herceptin may have greater role in treating HER2-negative breast cancer

Resolve Therapeutics, Takeda partner to develop compounds for treatment of lupus

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

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