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Finerenone: A promising therapeutic option for cardiovascular diseases

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Mineralocorticoid receptor antagonists (MRA) have significant therapeutic effects on heart failure, hypertension, chronic kidney disease and primary aldosteronism.

11 Oct 2023

A novel drug reduces the monthly frequency of seizure in adults with focal epilepsy

The effect of a novel Kv7.2/Kv7.3 potassium channel opener XEN1101 in reducing monthly seizure frequency in adults.

11 Oct 2023

Intermittent use of benzodiazepines linked with fewer side effects

More than 60 years after being introduced, doctors have uncovered the first reliable evidence to confirm the belief that taking benzodiazepines such as Valium and Ativan intermittently rather than continuously is associated with fewer side effects and reduced falls, hospitalizations and deaths.

9 Oct 2023

Research explains the reason behind delay in therapeutic action of antidepressants

SSRI antidepressants normally take a few weeks before any showing mental health benefits, but how come it takes so long? Now a study from a group of clinicians and scientists provides the first human evidence that this is due to physical changes in the brain leading to greater brain plasticity developing over the first few weeks of SSRI intake.

9 Oct 2023

Psychedelics may increase neuroplasticity by promoting the remodeling of synaptic connections

Intrusive thoughts, involuntary repetition of undesirable gestures and behaviors combined with high anxiety... Obsessive-compulsive disorder (OCD), a disabling condition, affects around 2% of the population, regardless of age.

9 Oct 2023

Next-gen intranasal vaccine takes on measles, mumps, and multiple COVID-19 variants in one shot

Researchers developed an intranasal trivalent measles-mumps-SARS-CoV-2 vaccine that provides robust protection against multiple coronavirus variants. Leveraging the established measles-mumps-rubella platform, this vaccine demonstrates broad and adaptable immune responses, especially against Delta and Omicron variants.

8 Oct 2023

Novavax vaccine shows resilient defense against symptomatic COVID-19 despite Omicron challenge

Recent study assesses NVX-CoV2373 vaccine's effectiveness against Omicron variant. Findings show decreased efficacy over four months, but stable protection against symptomatic COVID-19.

8 Oct 2023

The potential benefits of ribavirin and pleconaril treatment on type 1 diabetes

Researchers investigate whether ribavirin and pleconaril could stimulate endogenous insulin production among individuals with incident type 1 diabetes.

8 Oct 2023

Nirmatrelvir and ritonavir combo cuts COVID-19 risks for high-vulnerability groups

Nirmatrelvir and ritonavir treatment significantly reduces the risk of hospitalization and death from COVID-19 in high-risk individuals, according to a recent JAMA Network Open study. However, the treatment's efficacy varied based on the degree of vulnerability, emphasizing tailored approaches for different risk groups.

8 Oct 2023

Protein recombinant vaccine NVX-CoV2373 confers protection during Omicron dominant period in Italy

The NVX-CoV2373 COVID-19 vaccine offers significant protection against symptomatic infections, but its effectiveness against SARS-CoV-2 declines within four months, according to a study in JAMA Network Open using Italian data. However, its protection against symptomatic COVID-19 seems to remain stable during this period.

8 Oct 2023

Trump misplaced blame when he said drug shortages were Biden’s fault

"Under 'Crooked Joe' Biden, there has been a catastrophic increase in shortages of essential medicines."

6 Oct 2023

Why are most Americans skipping the COVID-19 booster?

A study in the journal Vaccine reveals that misinformation and concerns about side effects are leading reasons why over 80% of eligible Americans have skipped the SARS-CoV-2 vaccine booster. The research underscores the need for more public education about the vaccine's benefits in combating severe COVID-19 infections.

5 Oct 2023

How is TikTok's #Ozempic trend impacting diabetes patients?

A recent study analyzed TikTok videos with the hashtag "Ozempic," highlighting the platform's influence on promoting the weight loss drug. The surge in popularity resulted in medication shortages for diabetes patients, emphasizing the need for careful monitoring and collaboration among health professionals and social media platforms.

5 Oct 2023

GLP-1 weight loss drugs linked to heightened GI risks, says new study

Study from JAMA reveals that users of GLP-1 agonists, recent drugs for weight management, show a heightened risk of gastrointestinal complications like intestinal obstruction, gastroparesis, and pancreatitis. Though these effects are rare, those considering these drugs for weight loss should weigh the benefits against potential risks, especially if not using them for diabetes.

5 Oct 2023

GLP-1 agonists linked to higher risk for gastrointestinal complications

They're being hailed as an effective way to lose weight, but diabetes drugs like Ozempic may come with a heightened risk of severe gastrointestinal problems.

5 Oct 2023

Can falsified or substandard antimicrobials increase antimicrobial resistance?

The association between substandard or falsified (SF) antibiotics and antimicrobial resistance (AMR).

5 Oct 2023

Esketamine nasal spray superior in achieving remission in patients with treatment-resistant depression

Both severe depression and treatment-resistant depression are common. Up to one third of patients do not respond to conventional therapy with antidepressants such as selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs).

5 Oct 2023

New drug tirzepatide equally effective in early-onset and later-onset type 2 diabetes

Tirzepatide is as effective at treating early-onset type 2 diabetes (T2D), a more aggressive form of the condition that normally responds less well to treatment, as it is at treating T2D diagnosed later in life, new research being presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Hamburg, Germany (2-6 Oct) has found.

4 Oct 2023

Prioritising Lung Health: How FeNO can help to tackle Lung Conditions, the UK's 3rd Largest Threat

A new report from PwC commissioned by Asthma+Lung UK has highlighted the alarming crisis surrounding Lung Health in the UK.

From NObreath 4 Oct 2023

Octopus-inspired suction patch revolutionizes drug delivery, promising an injection-free future

Scientists develop an octopus sucker-inspired buccal mucosa suction patch, enhancing systemic absorption of macromolecular drugs. This innovative, non-invasive delivery platform, validated on porcine and human subjects, presents a potential alternative to intravenous injections for better drug bioavailability and patient compliance.

4 Oct 2023

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Pharmaceutical News

Finerenone: A promising therapeutic option for cardiovascular diseases

A novel drug reduces the monthly frequency of seizure in adults with focal epilepsy

Intermittent use of benzodiazepines linked with fewer side effects

Research explains the reason behind delay in therapeutic action of antidepressants

Psychedelics may increase neuroplasticity by promoting the remodeling of synaptic connections

Next-gen intranasal vaccine takes on measles, mumps, and multiple COVID-19 variants in one shot

Novavax vaccine shows resilient defense against symptomatic COVID-19 despite Omicron challenge

The potential benefits of ribavirin and pleconaril treatment on type 1 diabetes

Nirmatrelvir and ritonavir combo cuts COVID-19 risks for high-vulnerability groups

Protein recombinant vaccine NVX-CoV2373 confers protection during Omicron dominant period in Italy

Trump misplaced blame when he said drug shortages were Biden’s fault

Why are most Americans skipping the COVID-19 booster?

How is TikTok's #Ozempic trend impacting diabetes patients?

GLP-1 weight loss drugs linked to heightened GI risks, says new study

GLP-1 agonists linked to higher risk for gastrointestinal complications

Can falsified or substandard antimicrobials increase antimicrobial resistance?

Esketamine nasal spray superior in achieving remission in patients with treatment-resistant depression

New drug tirzepatide equally effective in early-onset and later-onset type 2 diabetes

Prioritising Lung Health: How FeNO can help to tackle Lung Conditions, the UK's 3rd Largest Threat

Octopus-inspired suction patch revolutionizes drug delivery, promising an injection-free future

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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