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New anti-tumor compounds show promise for hard-to-treat cancers

New anti-tumor compounds produced by Dr. Aleem Gangjee, Distinguished Professor of Medicinal Pharmacy at Duquesne University's Mylan School of Pharmacy, show such promise for fighting hard-to-treat tumors that the National Institutes of Health (NIH) has placed them on its fast track for development.

6 Jan 2012

Tetragenetics reports results from G-SOME H5N1 vaccine preclinical study

Tetragenetics Inc., a biotechnology company focused on the development of recombinant vaccines, today reported preclinical study results showing that an investigational nanoparticle-based influenza vaccine protects against a highly pathogenic H5N1 avian influenza strain.

6 Jan 2012

Researchers identify potential target for schistosomiasis vaccine

In the complicated life cycle of ancient flatworms that cause schistosomiasis, Case Western Reserve University researchers have identified a gene activator crucial to development of the parasites within humans - a potential target for a vaccine.

6 Jan 2012

Combination of cancer drugs shows promise against Pompe disease

Kids with Pompe disease fail because of a missing enzyme, GAA, that leads to dangerous sugar build-up, which affects muscles and movement. An enzyme replacement treatment pioneered at Duke University has saved many lives, but some children with Pompe disease produce an immune reaction that blocks the benefits of the life-saving enzyme treatment.

6 Jan 2012

Ipsen, Oncodesign partner to discover and develop LRRK2 kinase inhibitors against PD

Oncodesign, a Drug Discovery company and Oncology pharmacology service provider, and Ipsen, a global specialty-driven pharmaceutical company, announced today that the two companies have entered into a research collaboration to discover and develop innovative LRRK2 kinase inhibitors as potential therapeutic agents against Parkinson's Disease and for potential additional uses in other therapeutic areas.

5 Jan 2012

USP seeks feedback on recommendations for pharmaceutical supply chain integrity

As the pharmaceutical industry continues to globalize, the challenges of securing complex supply chains and protecting patients from counterfeit medicines, as well as the consequences of lapses in security or proper handling, have mounted.

5 Jan 2012

Vitamin D may stop conferring cardiovascular benefits: Study

New research by Johns Hopkins scientists suggests that vitamin D, long known to be important for bone health and in recent years also for heart protection, may stop conferring cardiovascular benefits and could actually cause harm as levels in the blood rise above the low end of what is considered normal.

5 Jan 2012

Novel vaccine combinations can protect against infection by SIV

Results from a recent study show that novel vaccine combinations can provide partial protection against infection by Simian Immunodeficiency Virus (SIV) in rhesus monkeys.

5 Jan 2012

IARS celebrates 90 years of support of anesthesia-related research

The International Anesthesia Research Society (IARS), the oldest professional society for anesthesiologists, originally founded as the National Anesthesia Research Society, celebrates 90 years of support of medical research in 2012.

5 Jan 2012

Study: Drug research often suppressed

Drug research, even from clinical trials sponsored by the federal government, routinely is suppressed, harming patients and increasing health care costs, according to new data highlighting an ethical controversy that continues to plague the field of medicine.

5 Jan 2012

Doctors may need to adjust seizure drug doses for people with HIV/AIDS: New AAN guideline

A new guideline issued by the American Academy of Neurology recommends doctors use caution when choosing seizure drugs for people with HIV/AIDS to avoid potential drug interactions.

5 Jan 2012

Re-introduction of rotavirus vaccine does not increase intussusception rates in the U.S.

The rotovirus vaccine was pulled from the marketplace in 1999 after being associated with painful gastrointestinal complications, however, the updated rotavirus vaccines do not appear to increase the occurrence of these potentially fatal side effects, according to a new study by child health experts at C.S. Mott Children's Hospital.

5 Jan 2012

Licorice root may play a role in treating and preventing gum disease, tooth decay

Scientists are reporting identification of two substances in licorice - used extensively in Chinese traditional medicine - that kill the major bacteria responsible for tooth decay and gum disease, the leading causes of tooth loss in children and adults.

5 Jan 2012

FDA issues order prohibiting certain uses of cephalosporins in food-producing animals

The U.S. Food and Drug Administration today issued an order that prohibits certain uses of the cephalosporin class of antimicrobial drugs in cattle, swine, chickens and turkeys effective April 5, 2012.

5 Jan 2012

Antiestrogen supplements may reduce risk of melanoma in women with breast cancer

Women with breast cancer who take antiestrogen supplements may be decreasing their risk for melanoma, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research.

5 Jan 2012

First study to elucidate how statins reduce activation of abnormal blood clotting

People with high cholesterol are at risk of heart attack and stroke because atherosclerotic plaques within their arteries can rupture triggering the formation of a blood clot called an occlusive thrombus that cuts off the blood supply to their heart or brain.

5 Jan 2012

Study reveals factors associated with prevention, control of HIV infection

New vaccine research in monkeys suggests that scientists are homing in on the critical ingredients of a protective HIV vaccine and identifies new HIV vaccine candidates to test in human clinical trials.

5 Jan 2012

NGP receives investment from Abbott to develop NGP 555 for AD

NeuroGenetic Pharmaceuticals, Inc. (NGP), a privately held biopharmaceutical company focused on Alzheimer's disease (AD) therapeutics, has received an investment from Abbott Biotech Ventures.

5 Jan 2012

Arcion receives U.S. patent allowance for ARC-2022 to treat PHN

Arcion Therapeutics, a clinical stage biotechnology company developing topical therapies for chronic pain, today announced that it received notice of allowance for a US Patent for its high strength gel formulation of topical lidocaine, ARC-2022.

5 Jan 2012

Actavis commences distribution of Methylphenidate Hydrochloride Extended-Release Capsules

Actavis Group, an international generic pharmaceuticals company, today announced that it recently received approval from the US Food & Drug Administration to market Methylphenidate Hydrochloride Extended-Release Capsules (LA) CII, USP, 20mg, 30mg, and 40mg. Actavis has first-to-file exclusivity on the 20mg, 30mg, and 40mg strengths.

4 Jan 2012

Pharmaceutical News

New anti-tumor compounds show promise for hard-to-treat cancers

Tetragenetics reports results from G-SOME H5N1 vaccine preclinical study

Researchers identify potential target for schistosomiasis vaccine

Combination of cancer drugs shows promise against Pompe disease

Ipsen, Oncodesign partner to discover and develop LRRK2 kinase inhibitors against PD

USP seeks feedback on recommendations for pharmaceutical supply chain integrity

Vitamin D may stop conferring cardiovascular benefits: Study

Novel vaccine combinations can protect against infection by SIV

IARS celebrates 90 years of support of anesthesia-related research

Study: Drug research often suppressed

Doctors may need to adjust seizure drug doses for people with HIV/AIDS: New AAN guideline

Re-introduction of rotavirus vaccine does not increase intussusception rates in the U.S.

Licorice root may play a role in treating and preventing gum disease, tooth decay

FDA issues order prohibiting certain uses of cephalosporins in food-producing animals

Antiestrogen supplements may reduce risk of melanoma in women with breast cancer

First study to elucidate how statins reduce activation of abnormal blood clotting

Study reveals factors associated with prevention, control of HIV infection

NGP receives investment from Abbott to develop NGP 555 for AD

Arcion receives U.S. patent allowance for ARC-2022 to treat PHN

Actavis commences distribution of Methylphenidate Hydrochloride Extended-Release Capsules

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

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