Pharmaceutical News

RSS

BIDMC researcher says improvement in survival rates best 'since introduction of aspirin'

An oral anti-clotting drug, when added to standard medical treatment for acute coronary syndrome, lowered the risk of death, heart attack or stroke an average of 16 percent, according to research presented at the American Heart Association's Scientific Sessions.

14 Nov 2011

Dyax and Defiante decide to withdraw KALBITOR MAA filed with EMA

Dyax Corp. announced today an update on KALBITOR's international regulatory status.

14 Nov 2011

Scientists discover molecular basis for tamoxifen resistance and potential way to defeat it

In the last three decades, thousands of women with breast cancer have taken the drug tamoxifen, only to discover that the therapy doesn't work, either because their tumors do not respond to the treatment at all, or because they develop resistance to it over time. Now researchers at the University of California, San Francisco (UCSF) have discovered the molecular basis for tamoxifen resistance and found a potential way to defeat it.

14 Nov 2011

Scientists create new phenotypic cancer drug screening platform

Researchers have created a new phenotypic screening platform that better predicts success of drugs developed to prevent blood vessel tumor growth when moving out of the lab and onto actual tumors.

14 Nov 2011

Next-generation drugs may prevent skin lesions in BRAF mutation-positive melanoma

Findings from preclinical studies in a skin cancer model showed that next-generation BRAF inhibitors used alone, or first-generation BRAF inhibitors used in combination with an epidermal growth factor receptor inhibitor, may have the potential to prevent drug-induced skin lesions in BRAF mutation-positive patients treated for melanoma.

14 Nov 2011

ZIOPHARM announces darinaparsin preclinical data on prostate cancer

ZIOPHARM Oncology, Inc., a drug development company employing small molecule and synthetic biology approaches to cancer therapy, announced today that results from preclinical studies of darinaparsin (Zinapar or ZIO-101), a novel organic arsenic, in prostate cancer were presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, taking place November 12-16 in San Francisco.

14 Nov 2011

Combination of REGN910 and aflibercept inhibits tumor angiogenesis in animal models

Combining the investigational agents REGN910 and aflibercept yielded statistically significant improvements in antitumor effects in animal models compared with either agent alone, according to results presented at the AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics, held Nov. 12-16, 2011.

14 Nov 2011

Researchers show how ER-positive breast cancer tumors become resistant to tamoxifen

Researchers have shown how estrogen receptor-positive breast cancer tumors become resistant to tamoxifen, the only approved hormonal therapy for premenopausal patients with this type of breast cancer.

14 Nov 2011

Low levels of vitamin C associated with worse outcomes for heart failure patients

Low levels of vitamin C were associated with higher levels of high sensitivity C-Reactive protein (hsCRP) and shorter intervals without major cardiac issues or death for heart failure patients, in research presented at the American Heart Association's Scientific Sessions 2011.

14 Nov 2011

Older patients less likely to receive pain medication in hospital EDs

A new study finds that people 75 years old or older are less likely to receive any pain medication in hospital emergency departments than middle aged people - those between 35 and 54 years old.

13 Nov 2011

IVI receives WHO prequalification for new oral cholera vaccine

Shanchol-, a new oral cholera vaccine developed through the International Vaccine Institute (IVI), an international organization established by the United Nations and based in Seoul, recently received prequalification from the World Health Organization.

13 Nov 2011

Opioid-dependent patients have worse outcomes before knee replacement surgery

Patients who are dependent on opioids (narcotic pain relievers) for pain management before knee replacement surgery have much more difficulty recovering, a study recently published in the Journal of Bone and Joint Surgery (JBJS) has found.

13 Nov 2011

Brazilian Ministry of Health, Bristol-Myers Squibb sign technology transfer agreement for Reyataz

Bristol-Myers Squibb Company today announced a technology transfer agreement with the Brazilian Ministry of Health to expand access to Reyataz (atazanavir sulfate) in Brazil.

13 Nov 2011

NICE refuses AstraZeneca breast cancer drug on NHS

Britain’s National Institute for Health and Clinical Excellence (NICE) has refused another breast cancer drug from routine NHS use. This was not met with enthusiasm by the cancer charities which said that drugs of this type are “particularly valuable”.

13 Nov 2011

Inflammatory arthritis or autoimmune disease ruled out as cause for joint pain associated with AIs

Researchers exploring why some women who take a common breast cancer drug develop serious joint pain have eliminated two possible causes: inflammatory arthritis and autoimmune disease.

11 Nov 2011

Actavis begins shipping Morphine Sulfate Extended-Release Capsules

Actavis, an international generic pharmaceutical company, today announced that it has begun shipping Morphine Sulfate Extended-Release Capsules, USP CII, an authorized generic of KADIAN.

11 Nov 2011

Vaccination dramatically reduces incidence of Hib disease in young children

Vaccination against Haemophilus influenzae type b, or Hib, once the most common cause of bacterial meningitis in children, has dramatically reduced the incidence of Hib disease in young children over the past 20 years, according to a study published in Clinical Infectious Diseases and available online.

11 Nov 2011

Worm model to evaluate drugs for Parkinson's disease

Researchers at The University of Texas at Austin have devised a simple test, using dopamine-deficient worms, for identifying drugs that may help people with Parkinson's disease.

11 Nov 2011

New process allows for more rapid and cheaper separation of enantiomers

Enantiomers are pairs of molecules built in a mirror-inverted manner. They differ from each other like a left and a right glove. This property of the molecules that is referred to as chirality is of particular relevance to biosciences and pharmaceutics. "While many, especially smaller, molecules like carbon dioxide or methane are not chiral, many biologically relevant molecules, such as tartaric acid have this property," explains Professor Christof W-ll, Head of the KIT Institute of Functional Interfaces.

11 Nov 2011

Pharmaceutical industry should invest more in NTDs

In this Forbes opinion piece, contributor Sarika Bansal examines "what needs to happen for the pharmaceutical industry, academic researchers, and other key players to begin investing more seriously in" neglected tropical diseases.

11 Nov 2011

Pharmaceutical News

BIDMC researcher says improvement in survival rates best 'since introduction of aspirin'

Dyax and Defiante decide to withdraw KALBITOR MAA filed with EMA

Scientists discover molecular basis for tamoxifen resistance and potential way to defeat it

Scientists create new phenotypic cancer drug screening platform

Next-generation drugs may prevent skin lesions in BRAF mutation-positive melanoma

ZIOPHARM announces darinaparsin preclinical data on prostate cancer

Combination of REGN910 and aflibercept inhibits tumor angiogenesis in animal models

Researchers show how ER-positive breast cancer tumors become resistant to tamoxifen

Low levels of vitamin C associated with worse outcomes for heart failure patients

Older patients less likely to receive pain medication in hospital EDs

IVI receives WHO prequalification for new oral cholera vaccine

Opioid-dependent patients have worse outcomes before knee replacement surgery

Brazilian Ministry of Health, Bristol-Myers Squibb sign technology transfer agreement for Reyataz

NICE refuses AstraZeneca breast cancer drug on NHS

Inflammatory arthritis or autoimmune disease ruled out as cause for joint pain associated with AIs

Actavis begins shipping Morphine Sulfate Extended-Release Capsules

Vaccination dramatically reduces incidence of Hib disease in young children

Worm model to evaluate drugs for Parkinson's disease

New process allows for more rapid and cheaper separation of enantiomers

Pharmaceutical industry should invest more in NTDs

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

Latest News