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Bivalent mRNA vaccine induces powerful antibody response to SARS-CoV-2 Omicron subvariants

Researchers discuss the development and efficacy of a bivalent mRNA vaccine against emerging variants such as BA.2.12.1, BA.4, or BA.5.

25 Jul 2022

Researchers investigate a drug used for neuromuscular weakness as potential treatment for botulism

Wake Forest Institute for Regenerative Medicine (WFIRM) researchers are investigating a drug used to treat neuromuscular weakness as a potential treatment for botulism, a rare but serious disease.

25 Jul 2022

KHN’s ‘What the Health?’: Drug price bill is a go in the Senate

President Joe Biden is the latest top Washington official to test positive for covid-19, following Vice President Kamala Harris, Speaker of the House Nancy Pelosi, and Senate Majority Leader Chuck Schumer. But work continues, particularly on a Senate bill that could, for the first time, allow Medicare to negotiate prescription drug prices and cap seniors' out-of-pocket medication costs.

21 Jul 2022

AbbVie Submits Marketing Authorization Application to EMA for Atogepant for the Preventive Treatment of Migraine

AbbVie today announced it has submitted a marketing authorization application (MAA) to the European Medicines Agency (EMA) for atogepant for the prophylaxis of migraine in adult patients who have at least four migraine days per month.

From AbbVie 21 Jul 2022

High-level resistance of SARS-CoV-2 BA.4 against neutralizing antibodies

Researchers evaluates the sensitivity of BA.4 in both vaccinated and unvaccinated individuals infected with the SARS-CoV-2 variants.

20 Jul 2022

COVID vaccines induce memory B and T cells in primary antibody deficient patients

The SARS-CoV-2-specific B- and T-cell response post-COVID-19 primary and booster vaccination in primary antibody deficient patients.

20 Jul 2022

Fourth dose of Pfizer mRNA COVID vaccine protective against variants and symptomatic infection

Researchers evaluate the efficacy of three- and four-dose regimens of a mRNA-based COVID-19 vaccine in reducing the risk of symptomatic infection.

20 Jul 2022

Potential mRNA vaccines for influenza

Scientists discuss the benefits of shifting the global influenza vaccination system to a mRNA-based platform,

19 Jul 2022

High-dose Vitamin B6 tablets could reduce feelings of anxiety and depression

Taking high-dose Vitamin B6 tablets has been shown to reduce feelings of anxiety and depression by new research.

19 Jul 2022

Novel nanoligomer approach to treat severe COVID-19

Researchers discuss the biodistribution and safety of a novel nanoligomer SBCoV207, which was used to targeted miR-2392 in a murine model.

17 Jul 2022

The potential of circular RNA COVID-19 vaccines

A new MedComm study describes the potential use of circular ribonucleic acid COVID-19 vaccines.

17 Jul 2022

Study: Prescribing rate of non-opioid pain medications increased after 2016 CDC guideline

After the Centers for Disease Control and Prevention released a guideline for prescribing opioids to patients experiencing chronic pain in 2016, the prescribing rate of non-opioid pain medication increased each year above and beyond what would be expected based on the preexisting trends, a new study finds.

15 Jul 2022

As Big Pharma loses interest in new antibiotics, infections are only growing stronger

Forget covid-19, monkeypox, and other viruses for the moment and consider another threat troubling infectious disease specialists: common urinary tract infections, or UTIs, that lead to emergency room visits and even hospitalizations because of the failure of oral antibiotics.

15 Jul 2022

Sore throat lozenges and sprays provide only a small reduction in throat pain

It's hard to get through a winter without suffering sore throat, but luckily they normally get better within a few days.

15 Jul 2022

Prescribing lower quantities of opioids may effectively control postoperative pain after knee surgery

Prescribing smaller quantities of opioid medication appears to be as effective in controlling postoperative pain after knee surgery as higher quantities and may help to limit the number of opioids prescribed and possible diversion of unused prescription opioid medication, according to research presented today at the American Orthopaedic Society of Sports Medicine 2022 Annual Meeting

15 Jul 2022

Long-established drug for angina pectoris shows anti-inflammatory effect, reduces atherosclerotic plaques

A drug used in the clinical treatment of angina symptoms also has an anti-inflammatory effect and reduces atherosclerotic plaques in blood vessels - thereby reducing the risk of heart attack or stroke.

14 Jul 2022

Availability of lower-priced epinephrine auto-injectors did not solve the affordability problem for all patients with severe allergies

People with severe allergies now have more choices for which epinephrine auto-injector to carry in case they suffer a life-threatening attack, and most pay less for it than they did when the EpiPen was the primary option, a new study shows.

12 Jul 2022

Commonly prescribed class of migraine drugs may be effective in treating obesity

Triptans, a commonly prescribed class of migraine drugs, may also be useful in treating obesity, a new study by scientists at UT Southwestern suggests.

11 Jul 2022

Nanoparticle vaccine could protect against animal viruses including future SARS-CoV-2 variants

A recent study published in the Science journal depicted that mosaic receptor-binding domain (RBD) nanoparticles immunize from diverse sarbecovirus challenges, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), among animal models.

8 Jul 2022

Discovery of multiple new SARS-CoV-2 MPro inhibitors

In a recent study posted to the bioRxiv* preprint server, researchers performed an extensive library docking for new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro) covalent and non-covalent inhibitors.

8 Jul 2022

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Pharmaceutical News

Bivalent mRNA vaccine induces powerful antibody response to SARS-CoV-2 Omicron subvariants

Researchers investigate a drug used for neuromuscular weakness as potential treatment for botulism

KHN’s ‘What the Health?’: Drug price bill is a go in the Senate

AbbVie Submits Marketing Authorization Application to EMA for Atogepant for the Preventive Treatment of Migraine

High-level resistance of SARS-CoV-2 BA.4 against neutralizing antibodies

COVID vaccines induce memory B and T cells in primary antibody deficient patients

Fourth dose of Pfizer mRNA COVID vaccine protective against variants and symptomatic infection

Potential mRNA vaccines for influenza

High-dose Vitamin B6 tablets could reduce feelings of anxiety and depression

Novel nanoligomer approach to treat severe COVID-19

The potential of circular RNA COVID-19 vaccines

Study: Prescribing rate of non-opioid pain medications increased after 2016 CDC guideline

As Big Pharma loses interest in new antibiotics, infections are only growing stronger

Sore throat lozenges and sprays provide only a small reduction in throat pain

Prescribing lower quantities of opioids may effectively control postoperative pain after knee surgery

Long-established drug for angina pectoris shows anti-inflammatory effect, reduces atherosclerotic plaques

Availability of lower-priced epinephrine auto-injectors did not solve the affordability problem for all patients with severe allergies

Commonly prescribed class of migraine drugs may be effective in treating obesity

Nanoparticle vaccine could protect against animal viruses including future SARS-CoV-2 variants

Discovery of multiple new SARS-CoV-2 MPro inhibitors

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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