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Genta commences tesetaxel Phase 2b clinical trial as 1st-line chemotherapy for metastatic breast cancer

Genta Incorporated today announced that the Company has initiated a new Phase 2b clinical trial of tesetaxel as 1st-line chemotherapy for women with metastatic breast cancer. Tesetaxel is the leading oral taxane currently in clinical development. The new trial will be conducted at Memorial Sloan-Kettering Cancer Center, New York, NY and at the Accelerated Community Oncology Research Network (ACORN) based in Memphis, TN.

9 Nov 2010

Statins do not reduce risk for colorectal cancer in postmenopausal women

The use of statins among a group of postmenopausal women did not reduce the risk for colorectal cancer, according to the results of a prospective analysis of data from the large population-based Women's Health Initiative (WHI).

9 Nov 2010

Family history of HG increases risk of extreme morning sickness during pregnancy

Approximately 60,000 pregnant women are hospitalized each year due to hyperemesis gravidarum (HG), an extreme form of nausea and vomiting that endangers their lives and often forces them to reluctantly terminate their pregnancies.

9 Nov 2010

Sec. Clinton highlights importance of U.S.-Australia partnership to reduce violence against women worldwide

As part of her two-week Asia-Pacific tour, Secretary of State Hillary Rodham Clinton was in Australia on Saturday, where she called for increased cooperation between Australia and the U.S. to help drive down violence against women globally, Bloomberg reports.

9 Nov 2010

Denosumab superior to Zometa in preventing SREs in breast cancer patients with bone metastases: Study

Amgen today announced the publication of results from a pivotal Phase 3 study of 2,046 patients which compared denosumab with Zometa® (zoledronic acid) in delaying or preventing skeletal-related events (SREs) in breast cancer patients with bone metastases. An SRE consists of any of the following: a pathologic fracture, the need for radiation or surgery to ameliorate bone pathology secondary to tumor growth, or spinal cord compression.

8 Nov 2010

Obesity does not increase breast cancer risk in Mexican-American women: Research

Obesity was not associated with breast cancer risk in Mexican-American women, even when measured at numerous ages throughout a woman's lifetime, according to data presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held here Nov. 7-10, 2010.

8 Nov 2010

Potential biomarker for measuring progress in breast cancer chemoprevention trials

Researchers at Duke University Medical Center have identified a possible biomarker for measuring progress in breast cancer chemoprevention trials, according to data presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held here Nov. 7-10, 2010.

8 Nov 2010

Soy isoflavone intake decreases risk of invasive breast tumor

Increased phytoestrogens commonly found in dietary soy may modify the risk of some types of breast cancer, according to findings presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held Nov. 7-10, 2010.

8 Nov 2010

Parascript receives $244,479.25 federal grant under Affordable Care Act

Parascript, LLC, the image analysis and pattern recognition technology provider, today announced that it was awarded a cash grant of $244,479.25 under the U.S. Government's Affordable Care Act. Under this act, the therapeutic discovery project program targets projects that show significant potential to produce new therapies, address unmet medical needs, reduce the long-term growth of health care costs or advance the goal of curing cancer within the next 30 years.

8 Nov 2010

Maternal peanut consumption during pregnancy increases peanut allergy risk in children

Babies born to mothers who eat peanuts during pregnancy appear more prone to peanut allergy, according to research conducted by scientists at Johns Hopkins Children's Center and elsewhere and published online in the Journal of Allergy and Clinical Immunology. The research team was led by Scott Sicherer, M.D., of the Mount Sinai School of Medicine in New York.

8 Nov 2010

FDA announces reclassification for Full Field Digital Mammography Systems

The U.S. Food and Drug Administration today announced that it is easing the pathway to market for mammography systems that produce computerized X-ray images of the entire breast.

8 Nov 2010

AAGL recommends vaginal or laparoscopic hysterectomies

Approximately 600,000 hysterectomies are performed in the United States annually to treat benign disorders of the pelvis. More than two-thirds are performed through an abdominal incision. In an evidence-based position statement published online today in The Journal of Minimally Invasive Gynecology, the AAGL, a medical specialty society of over 5,000 gynecologic surgeons, advocates the practice of performing these procedures vaginally or laparoscopically in a minimally invasive manner, thus reducing morbidity and facilitating a faster recovery period.

8 Nov 2010

People with SLE more likely to develop hematologic malignancies

People with systemic lupus erythematosus are 1.15 times as likely to develop cancer as the general population and more than 2.5 times as likely to develop hematologic malignancies, such as lymphoma and leukemia, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Atlanta.

8 Nov 2010

Amgen wins Scrip Best New Drug award for Prolia

Amgen is pleased to announce that it has won the Best New Drug award for Prolia™ (denosumab), a novel treatment approved in the United States (U.S.) for women with postmenopausal osteoporosis at high risk for fracture, at the 2010 Scrip Awards ceremony Nov. 4 in London. Named one of TIME's Top 10 Medical Breakthroughs of 2009, Prolia is the first treatment specifically designed to target osteoclasts, the cells that break down bone.

8 Nov 2010

Prolonged separation from mother increases risk of breast cancer in young mice

Young mice that experienced the psychosocial stress of prolonged separation from their mothers had a higher incidence and faster onset of breast tumors compared with young mice who did not experience this stressful life event. Specifically, neonatal mice separated from their mothers for a prolonged period of time developed mammary tumors twice as fast as mice that experienced short or no maternal separation.

8 Nov 2010

Novel serum test may help diagnose early pregnancy location and outcome

Researchers may have identified a promising novel diagnostic biomarker for ectopic pregnancy, according to a study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). In the western world, deaths from ectopic pregnancy are not common but in the developing world one in ten women who are admitted with an ectopic pregnancy die.

4 Nov 2010

Gender-related disparity in outcomes of lower extremities peripheral arterial disease continues: Study

Researchers from the Mount Sinai School of Medicine report that despite overall improvement, there is still gender-related disparity in outcomes of lower extremities peripheral arterial disease (PAD). Details of their study appear in the November issue of the Journal of Vascular Surgery®, published by the Society for Vascular Surgery®.

4 Nov 2010

Exposure to several AEDs in the womb negatively affect child's neurodevelopment

A large population-based study revealed that multiple antiepileptic drugs (AEDs) used by pregnant women to control seizures may cause poor school performance in their teenagers. The research team from Karolinska University Hospital and the University of Lund in Sweden confirmed that exposure to AEDs in utero may have a negative effect on neurodevelopment.

4 Nov 2010

During stop in Papua New Guinea, Secretary Clinton promotes women's rights

As part of Secretary of State Hillary Rodham Clinton's two-week Asia-Pacific tour, Clinton stopped in Papua New Guinea (PNG) on Wednesday to "promote human rights and women's empowerment in a South Pacific nation suffering from an epidemic of rape and police brutality," the Associated Press reports.

4 Nov 2010

One-third of breast cancer survivors rate breast-conserving treatments as fair

A third of breast cancer survivors who received the breast-conserving treatments lumpectomy and radiation rate the appearance of their post-treatment breast as only "fair" or "poor" in comparison to their untreated breast, according to a new University of Pennsylvania School of Medicine study that will be presented today at the 52nd Annual Meeting of the American Society for Radiation Oncology (ASTRO) in San Diego.

3 Nov 2010

Women's Health News

Genta commences tesetaxel Phase 2b clinical trial as 1st-line chemotherapy for metastatic breast cancer

Statins do not reduce risk for colorectal cancer in postmenopausal women

Family history of HG increases risk of extreme morning sickness during pregnancy

Sec. Clinton highlights importance of U.S.-Australia partnership to reduce violence against women worldwide

Denosumab superior to Zometa in preventing SREs in breast cancer patients with bone metastases: Study

Obesity does not increase breast cancer risk in Mexican-American women: Research

Potential biomarker for measuring progress in breast cancer chemoprevention trials

Soy isoflavone intake decreases risk of invasive breast tumor

Parascript receives $244,479.25 federal grant under Affordable Care Act

Maternal peanut consumption during pregnancy increases peanut allergy risk in children

FDA announces reclassification for Full Field Digital Mammography Systems

AAGL recommends vaginal or laparoscopic hysterectomies

People with SLE more likely to develop hematologic malignancies

Amgen wins Scrip Best New Drug award for Prolia

Prolonged separation from mother increases risk of breast cancer in young mice

Novel serum test may help diagnose early pregnancy location and outcome

Gender-related disparity in outcomes of lower extremities peripheral arterial disease continues: Study

Exposure to several AEDs in the womb negatively affect child's neurodevelopment

During stop in Papua New Guinea, Secretary Clinton promotes women's rights

One-third of breast cancer survivors rate breast-conserving treatments as fair

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Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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