Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Study suggests possible role for caffeine in AD treatment

The proposed link between caffeine and reductions in the beta amyloid plaque accumulation characteristic of Alzheimer's disease (AD) suggest a possible role for caffeine in AD treatment. The latest evidence linking beta amyloid protein to Alzheimer's disease and exploring the relationship between caffeine and beta amyloid are featured in a review article in Journal of Caffeine Research: The International Multidisciplinary Journal of Caffeine Science, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

31 Mar 2015

Complete review of amyloid-beta protein behind Alzheimer's disease

"It will still take many years to understand the mechanisms leading to the formation of the characteristic plaques seen in brains affected by Alzheimer's disease", explains Alessandro Laio, SISSA professor. "We know they are mostly a build-up of amyloid-beta peptide, the protein that research is currently focusing on". And, as of today, all those involved in biomolecular research on Alzheimer's will have access to a new and important instrument: an extensive and complete review of all scientific knowledge about this "killer protein" has in fact just been published in the journal Chemical Reviews.

31 Mar 2015

New Johns Hopkins mobile app educates care providers on improving sleep, overall health of patients

Experts from the Johns Hopkins Center for Sleep hope to help patients get a better night’s sleep by providing health care staff members with a basic educational tool on their smartphones.

31 Mar 2015

Study finds link between brain alterations and functional decline in women at risk for Alzheimer's disease

In their latest brain imaging study on women at risk for Alzheimer's disease, York University researchers have found deterioration in the pathways that serve to communicate signals between different brain regions needed for performing everyday activities such as driving a car or using a computer.

31 Mar 2015

Patient with severe Alzheimer's shows promising benefits during treatment with Bryostatin drug

Researchers at the Blanchette Rockefeller Neurosciences Institute and the Marshall University Joan C. Edwards School of Medicine announced their findings from a new study entitled, "PSEN1 Variant in a Family with Atypical AD." An Alzheimer patient with very severe disease, genetically confirmed to have a known variant of PSEN1, showed promising benefits during treatment with the drug Bryostatin 1.

30 Mar 2015

Big data helps discover gephyrin protein's connection in human history

Big data: It's a term we read and hear about often, but is hard to grasp. Computer scientists at Washington University in St. Louis' School of Engineering & Applied Science tackled some big data about an important protein and discovered its connection in human history as well as clues about its role in complex neurological diseases.

30 Mar 2015

Researchers present new studies on cognition and reasoning at CNS conference in San Francisco

Even rats can imagine: A new study finds that rats have the ability to link cause and effect such that they can expect, or imagine, something happening even if it isn't.

30 Mar 2015

Discovery opens new drug development avenues for treating multiple diseases

Researchers at the University of California, San Diego School of Medicine have discovered a control switch for the unfolded protein response (UPR), a cellular stress relief mechanism drawing major scientific interest because of its role in cancer, diabetes, inflammatory disorders and several neural degenerative disorders, including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS), otherwise known as Lou Gehrig's disease.

30 Mar 2015

Study: Blood test may help diagnose Fragile X syndrome related disorders in women

A blood test may shed new light on Fragile X syndrome related disorders in women, according to a new study published in the March 25, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology. Fragile X is the most common inherited form of intellectual disability and the most frequent genetic cause of autism.

30 Mar 2015

UW Medicine receives $6 million from Ellison Foundation to revolutionize care for people with Alzheimer's

Alzheimer's disease, a severe and progressive degenerative condition that leads to dementia, affects millions of people in the U.S. At present, there is no cure. Unless new treatments emerge, the Centers for Disease Control estimates that approximately 13.8 million people in the U.S. will live with Alzheimer's-related dementia by 2050.

29 Mar 2015

Public volunteers to highlight their role in improving care for patients at Sheffield Consumers in Research event

RESEARCH-active members of the public are to showcase how their vital work helps shape clinical research projects and improves care for patients at a free drop-in event in Sheffield City Centre on Wednesday 22 April.

27 Mar 2015

Transition announces positive results from ELND005 AME and renal clearance studies

Transition Therapeutics Inc. today announced results from two phase 1 clinical studies of neuropsychiatric drug candidate ELND005. These studies, an absorption-metabolism-excretion ("AME") study and a renal clearance study, are specialized clinical pharmacology trials that are required by the United States Food and Drug Administration for the approval of most drugs in development.

26 Mar 2015

Immunotherapy reverses memory problems in animal model of Alzheimer's disease

A new study from the University of Texas Medical Branch at Galveston has revealed that a single dose of an immunotherapy reverses memory problems in an animal model of Alzheimer's disease. The article appears in the March 25 issue of the Journal of Neuroscience.

26 Mar 2015

UCLA-led team validates first standardized protocol for tracking early signs of Alzheimer's disease

After six years of painstaking research, a UCLA-led team has validated the first standardized protocol for measuring one of the earliest signs of Alzheimer's disease -- the atrophy of the part of the brain known as the hippocampus.

26 Mar 2015

Serious head injuries may contribute to faster brain ageing, new study reveals

People who have suffered serious head injuries show changes in brain structure resembling those seen in older people, according to a new study.

25 Mar 2015

Having strong purpose in life may give you better brain health

Having a strong sense that your life has meaning and direction may make you less likely to develop areas of brain damage caused by blockages in blood flow as you age. This research is reported in the American Heart Association's journal Stroke.

25 Mar 2015

New research finds link between milk consumption and high levels of glutathione in the brain

New research conducted at the University of Kansas Medical Center has found a correlation between milk consumption and the levels of a naturally-occurring antioxidant called glutathione in the brain in older, healthy adults.

25 Mar 2015

Study: Progression of dysfunctional tau protein drives cognitive decline in Alzheimer's disease

By examining more than 3,600 postmortem brains, researchers at Mayo Clinic's campuses in Jacksonville, Florida, and Rochester, Minnesota, have found that the progression of dysfunctional tau protein drives the cognitive decline and memory loss seen in Alzheimer's disease.

24 Mar 2015

New report highlights the need for disclosing Alzheimer's diagnosis to patients

The Alzheimer's Association's 2015 Alzheimer's Disease Facts and Figures report, released today, found that only 45 percent of people with Alzheimer's disease or their caregivers say they were told the diagnosis by their doctor.

24 Mar 2015

Discontinuation of statin therapy may benefit patients with terminal illness

Discontinuing statin use in patients with late-stage cancer and other terminal illnesses may help improve patients' quality of life without causing other adverse health effects, according to a new study by led by researchers at the University of Colorado Anschutz Medical Campus and Duke University and funded by the National Institute of Nursing Research (NINR).

24 Mar 2015

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Study suggests possible role for caffeine in AD treatment

Complete review of amyloid-beta protein behind Alzheimer's disease

New Johns Hopkins mobile app educates care providers on improving sleep, overall health of patients

Study finds link between brain alterations and functional decline in women at risk for Alzheimer's disease

Patient with severe Alzheimer's shows promising benefits during treatment with Bryostatin drug

Big data helps discover gephyrin protein's connection in human history

Researchers present new studies on cognition and reasoning at CNS conference in San Francisco

Discovery opens new drug development avenues for treating multiple diseases

Study: Blood test may help diagnose Fragile X syndrome related disorders in women

UW Medicine receives $6 million from Ellison Foundation to revolutionize care for people with Alzheimer's

Public volunteers to highlight their role in improving care for patients at Sheffield Consumers in Research event

Transition announces positive results from ELND005 AME and renal clearance studies

Immunotherapy reverses memory problems in animal model of Alzheimer's disease

UCLA-led team validates first standardized protocol for tracking early signs of Alzheimer's disease

Serious head injuries may contribute to faster brain ageing, new study reveals

Having strong purpose in life may give you better brain health

New research finds link between milk consumption and high levels of glutathione in the brain

Study: Progression of dysfunctional tau protein drives cognitive decline in Alzheimer's disease

New report highlights the need for disclosing Alzheimer's diagnosis to patients

Discontinuation of statin therapy may benefit patients with terminal illness

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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