Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Nigral neuronal loss and α-synuclein pathology scrutinised in PD

The severity of neurodegeneration and local burden of α-synuclein are closely coupled during disease progression in Parkinson’s disease, a post-mortem study has found.

11 Aug 2014

In vivo dopaminergic imaging strongly correlates with brain pathology

Striatal dopamine transporter binding, assessed using single-photon emission computed tomography, is strongly correlated with substantia nigra cell counts assessed at postmortem, say the authors of a study.

11 Aug 2014

Inovio Pharmaceuticals reports increased revenue in second quarter 2014

Inovio Pharmaceuticals, Inc. today reported financial results for the quarter ended June 30, 2014. Total revenue was $3.8 million and $6.2 million for the three and six months ended June 30, 2014, compared to $786,000 and $2.2 million for the same periods in 2013.

11 Aug 2014

Scientists identify mechanism by which inherited neurological disease causes muscle weakness in men

Researchers at University of California, San Diego School of Medicine have identified the mechanism by which a rare, inherited neurodegenerative disease causes often crippling muscle weakness in men, in addition to reduced fertility.

11 Aug 2014

People who develop depression, MCI after age 65 are more vulnerable for accelerated brain aging

People who develop depression and mild cognitive impairment (MCI) after age 65 are more likely to have biological and brain imaging markers that reflect a greater vulnerability for accelerated brain aging, according to a study conducted by researchers at the University of Pittsburgh School of Medicine. The findings were published online in Molecular Psychiatry.

8 Aug 2014

Infectious prion protein is marker for variant Creutzfeldt-Jakob disease

The misfolded and infectious prion protein that is a marker for variant Creutzfeldt-Jakob disease - linked to the consumption of infected cattle meat - has been detected in the urine of patients with the disease by researchers at The University of Texas Health Science Center at Houston (UTHealth) Medical School.

8 Aug 2014

People diagnosed with MCI are more likely to increase risk of developing dementia

In a long-term, large-scale population-based study of individuals aged 55 years or older in the general population researchers found that those diagnosed with mild cognitive impairment (MCI) had a four-fold increased risk of developing dementia or Alzheimer's disease (AD) compared to cognitively healthy individuals.

7 Aug 2014

Low levels of vitamin D may double dementia, Alzheimer's risks

In the largest study of its kind, researchers suggests that in older people, not getting enough vitamin D may double the risk of developing dementia and Alzheimer's disease. The study is published in the August 6, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology.

7 Aug 2014

State highlights: New York hospital mergers surging; Calif. court says home health workers can't sue for damages, injuries associated with caring for Alzheimer's patients

A selection of health policy stories from New York, California, Ohio, Wisconsin and Massachusetts. Hospital takeovers are surging in the New York region, raising concerns that health costs could climb and care could change.

6 Aug 2014

7.0T NMR spectroscopy detects lesions in hippocampal neurons of Alzheimer's disease

Magnetic resonance spectroscopy can quantitatively analyze in vivo abnormalities of biochemical metabolism within brain tissue in a noninvasive and non-radioactive manner.

6 Aug 2014

Whey protein drink can control erratic glucose levels associated with type 2 diabetes

Blood sugar surges - after-meal glucose "spikes" - can be life threatening for the 29 million Americans with diabetes. Diabetic blood sugar spikes have been linked to cardiovascular disease, cancer, Alzheimer's disease, kidney failure, and retinal damage.

5 Aug 2014

New project aims to develop unique database on frailty and dementia

What is the relationship between frailty and dementia? Many studies acknowledge that frailty and dementia often coexist, but little research has been done on why that is the case.

5 Aug 2014

Researchers study effect of alcohol on neural activity using fruit flies

Seeking eventual solutions to problems ranging from alcoholism, cancer and Alzheimer's to finding better ways to clean contact lenses and use Lego models to build bridges, University of Houston (UH) students devoted the summer to some serious scholarship.

5 Aug 2014

Eating baked or broiled fish once a week is good for the brain

Eating baked or broiled fish once a week is good for the brain, regardless of how much omega-3 fatty acid it contains, according to researchers at the University of Pittsburgh School of Medicine.

5 Aug 2014

Study shows new potential mechanism to better understand AD in African Americans

Researchers from Boston University School of Medicine report that two rare variants in the AKAP9 gene significantly increase the risk of Alzheimer's disease (AD) in African-Americans.

4 Aug 2014

Neuralstem doses final patient with NSI-566 stem cells in Phase II trial

Neuralstem, Inc. announced that the final patient was treated in its Phase II trial using NSI-566 spinal cord-derived neural stem cells in the treatment of amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease).

4 Aug 2014

Researchers at NIH-FEI Living Lab for Structural Biology achieve breakthrough biological results

FEI is pleased to announce that researchers at the NIH-FEI Living Lab for Structural Biology have achieved breakthrough biological results, using FEI’s Titan Krios™ transmission electron microscope (TEM), to elucidate the structural mechanism by which glutamate receptors participate in the transmission of signals between neurons in the brain. Their work is described in Nature, “Structural Mechanism of Glutamate Receptor Activation and Desensitization,” by Meyerson, et al., (DOI: 10.1038/nature13603), http://www.nature.com/nature/journal/vaop/ncurrent/full/nature13603.html .

From Thermo Fisher Scientific – Electron Microscopy Solutions 4 Aug 2014

Review of recent advances in stem cell biology

Advances in stem cell research will provide enormous opportunities for both biological and future clinical applications.

4 Aug 2014

Researchers create most detailed molecular map for region associated with blinding diseases

Understanding eye diseases is tricky enough. Knowing what causes them at the molecular level is even more confounding.

3 Aug 2014

Viewpoints: GOP lawsuit against Obama on health law is not a 'stunt'; 'wisdom' lacking in the House; the danger of cyberattacks on hospitals

"So sue me" is President Obama's message to Congress. And on Wednesday the House of Representatives took up his taunt, authorizing a lawsuit to challenge the president's failure to faithfully execute provisions of the Affordable Care Act as passed by Congress. The House lawsuit is no "stunt," as Mr. Obama has characterized it.

1 Aug 2014

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Nigral neuronal loss and α-synuclein pathology scrutinised in PD

In vivo dopaminergic imaging strongly correlates with brain pathology

Inovio Pharmaceuticals reports increased revenue in second quarter 2014

Scientists identify mechanism by which inherited neurological disease causes muscle weakness in men

People who develop depression, MCI after age 65 are more vulnerable for accelerated brain aging

Infectious prion protein is marker for variant Creutzfeldt-Jakob disease

People diagnosed with MCI are more likely to increase risk of developing dementia

Low levels of vitamin D may double dementia, Alzheimer's risks

State highlights: New York hospital mergers surging; Calif. court says home health workers can't sue for damages, injuries associated with caring for Alzheimer's patients

7.0T NMR spectroscopy detects lesions in hippocampal neurons of Alzheimer's disease

Whey protein drink can control erratic glucose levels associated with type 2 diabetes

New project aims to develop unique database on frailty and dementia

Researchers study effect of alcohol on neural activity using fruit flies

Eating baked or broiled fish once a week is good for the brain

Study shows new potential mechanism to better understand AD in African Americans

Neuralstem doses final patient with NSI-566 stem cells in Phase II trial

Researchers at NIH-FEI Living Lab for Structural Biology achieve breakthrough biological results

Review of recent advances in stem cell biology

Researchers create most detailed molecular map for region associated with blinding diseases

Viewpoints: GOP lawsuit against Obama on health law is not a 'stunt'; 'wisdom' lacking in the House; the danger of cyberattacks on hospitals

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

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