Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Researchers find new drug target for mitochondrial dysfunction

Mitochondria, long known as "cellular power plants" for their generation of the key energy source adenosine triphosphate (ATP), are essential for proper cellular functions. Mitochondrial defects are often observed in a variety of diseases, including cancer, Alzheimer's disease, and Parkinson's disease, and are the hallmarks of a number of genetic mitochondrial disorders whose manifestations range from muscle weakness to organ failure. Despite a fairly strong understanding of the pathology of such genetic mitochondrial disorders, efforts to treat them have been largely ineffective.

28 Mar 2014

Researchers review influence of lipid rafts on progression of Alzheimer's disease

Research over decades has implicated aberrant autophagy and lysosomal function as reliable markers and therapeutic targets for neurodegenerative diseases.

27 Mar 2014

Alterations in eye movements when reading linked to early indication of Alzheimer's disease

Researchers have suggested that alterations in eye movements when reading could be linked to impairments in working memory and an early indication of Alzheimer's disease according to a new study published in the Journal of Clinical and Experimental Neuropsychology.

27 Mar 2014

Study seeks to adapt multi-family group treatment approach for people with spinal cord injury

Every year, more than 12,000 Americans-mostly young men-suffer spinal cord injuries in car crashes, falls, sports and acts of violence. Those dealing with this life-changing condition may soon have a better way to cope, thanks to a new collaborative research project by Washington State University Spokane and St. Luke's Rehabilitation Institute.

27 Mar 2014

Research points strong reason to develop new class of antidepressant drug

Scientists have shown for the first time that a chemical in the brain called galanin is involved in the risk of developing depression.

From The University of Manchester 27 Mar 2014

A fast, non-invasive method to genotype late-onset Alzheimer's disease

The apolipoprotein E gene ε4 allele is considered a negative factor for neural regeneration in late-onset Alzheimer's disease cases.

27 Mar 2014

Study: Dab2 can exhibit neuroprotective effects in Alzheimer's by regulating TGF-β1/SMAD signaling

Transforming growth factor-beta (TGF-β) type II receptor (TβRII) levels are extremely low in the brain tissue of patients with Alzheimer's disease.

27 Mar 2014

Cogstate's cognition test to play key role in A4 trial for Alzheimer’s disease

Cognition testing technology developed by Cogstate will be used to track the neurological health of elderly people involved in the multinational Phase III clinical trial of a promising new Alzheimer’s disease (AD) drug.

26 Mar 2014

Adult day care services may protect family caregivers against harmful effects of stress

Family caregivers show an increase in the beneficial stress hormone DHEA-S on days when they use an adult day care service for their relatives with dementia, according to researchers at Penn State and the University of Texas at Austin.

26 Mar 2014

Diabetes drug reduces amyloid-beta peptides, improves memory in experimental AD models

Researchers from Boston University School of Medicine have found that the diabetic drug, pramlintide, reduces amyloid-beta peptides, a major component of Alzheimer's disease (AD) in the brain and improves learning and memory in two experimental AD models.

25 Mar 2014

Viewpoints: Predictions of rising premiums in 2015; anniversary of health law

No one challenges reality like Kathleen Sebelius, who assured the world on Sept. 30, 2013 that the Affordable Care Act website would be open for business the next day. "We're very excited about tomorrow," Sebelius said. "Shutdown or no shutdown, we're ready to go."

24 Mar 2014

New treatment could halt progression of dementia

Researchers at the University of Texas Medical Branch at Galveston have discovered a way to potentially halt the progression of dementia caused by accumulation of a protein known as tau.

21 Mar 2014

People who develop diabetes in middle age are more likely to have brain cell loss in old age

People who develop diabetes and high blood pressure in middle age are more likely to have brain cell loss and other damage to the brain, as well as problems with memory and thinking skills, than people who never have diabetes or high blood pressure or who develop it in old age, according to a new study published in the March 19, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology.

20 Mar 2014

Scientists to study memory and learning in patients with Parkinson disease

Kessler Foundation scientists collaborated with colleagues in Spain to study memory and learning in patients with Parkinson Disease (PD). They found that the Parkinson group's ability to learn new information was significantly poorer when compared with the control group.

20 Mar 2014

PredictND project aims at validating new procedures for early diagnosis of memory disorders

The PredictND project, started by European research organisations, aims at developing and validating new procedures for the earlier diagnosis of memory disorders and for detecting individuals at high risk of developing memory disorders. Millions of Europeans who are at risk for experiencing any kind of memory loss would benefit from such a solution.

19 Mar 2014

COPD in older adults linked with increased risk for mild cognitive impairment

A diagnosis of chronic obstructive pulmonary disease (COPD) in older adults was associated with increased risk for mild cognitive impairment (MCI), especially MCI of skills other than memory, and the greatest risk was among patients who had COPD for more than five years.

19 Mar 2014

Computer analysis of various subtypes of asthma could eventually lead to improved therapy, says study

So many variables can contribute to shortness of breath that no person can keep them all straight. But a computer program, capable of tracking more than 100 clinical variables for almost 400 people, has shown it can identify various subtypes of asthma, which perhaps could lead to targeted, more effective treatments.

19 Mar 2014

Neuralstem announces results from Phase I trial using NSI-566 spinal cord stem cells in treatment of ALS

Neuralstem, Inc. (NYSE MKT: CUR) announced that the final results from the Phase I safety trial using NSI-566 spinal cord stem cells in the treatment of amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease) were published in the peer-reviewed journal, "Annals of Neurology".

18 Mar 2014

Scientists develop new mechanism that helps decode amyloid plaque formation in brains of Alzheimer's patients

University of Michigan researchers have learned how to fix a cellular structure called the Golgi that mysteriously becomes fragmented in all Alzheimer's patients and appears to be a major cause of the disease.

18 Mar 2014

Eye abnormalities may help reveal features of early-stage Alzheimer's disease, says study

Investigators at the Cedars-Sinai Regenerative Medicine Institute have discovered eye abnormalities that may help reveal features of early-stage Alzheimer's disease. Using a novel laboratory rat model of Alzheimer's disease and high-resolution imaging techniques, researchers correlated variations of the eye structure, to identify initial indicators of the disease.

18 Mar 2014

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Researchers find new drug target for mitochondrial dysfunction

Researchers review influence of lipid rafts on progression of Alzheimer's disease

Alterations in eye movements when reading linked to early indication of Alzheimer's disease

Study seeks to adapt multi-family group treatment approach for people with spinal cord injury

Research points strong reason to develop new class of antidepressant drug

A fast, non-invasive method to genotype late-onset Alzheimer's disease

Study: Dab2 can exhibit neuroprotective effects in Alzheimer's by regulating TGF-β1/SMAD signaling

Cogstate's cognition test to play key role in A4 trial for Alzheimer’s disease

Adult day care services may protect family caregivers against harmful effects of stress

Diabetes drug reduces amyloid-beta peptides, improves memory in experimental AD models

Viewpoints: Predictions of rising premiums in 2015; anniversary of health law

New treatment could halt progression of dementia

People who develop diabetes in middle age are more likely to have brain cell loss in old age

Scientists to study memory and learning in patients with Parkinson disease

PredictND project aims at validating new procedures for early diagnosis of memory disorders

COPD in older adults linked with increased risk for mild cognitive impairment

Computer analysis of various subtypes of asthma could eventually lead to improved therapy, says study

Neuralstem announces results from Phase I trial using NSI-566 spinal cord stem cells in treatment of ALS

Scientists develop new mechanism that helps decode amyloid plaque formation in brains of Alzheimer's patients

Eye abnormalities may help reveal features of early-stage Alzheimer's disease, says study

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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