Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Researcher finds possible way to unravel misfolded proteins by reprogramming yeast protein

At the heart of brain diseases such as amyotrophic lateral sclerosis, Alzheimer's disease, and Parkinson's disease is protein misfolding, in which distorted proteins are unable to perform their normal functions. At present, there is no known way to reverse protein misfolding.

17 Jan 2014

Research uncovers new mechanism in brain cells that may help keep deadly neurological diseases in check

New research from David Westaway, PhD, of the University of Alberta and Jiri Safar, MD, Case Western Reserve University School of Medicine has uncovered a quality control mechanism in brain cells that may help keep deadly neurological diseases in check for months or years.

17 Jan 2014

Higher vitamin D levels linked with better cognition and less depression in PD patients

A new study exploring vitamin D levels in patients with Parkinson's disease (PD) opens up the possibility of a new avenue of early intervention that may delay or prevent the onset of cognitive impairment and depression. The findings are published in the Journal of Parkinson's Disease.

16 Jan 2014

Study explores the role of DNA in predisposing individuals to diseases

A group of international researchers, led by a research fellow in the Harvard Medical School-affiliated Institute for Aging Research at Hebrew SeniorLife, published a paper today in Cell describing a study aimed at better understanding how inherited genetic differences, or variants, predispose certain individuals to develop diseases such as type 2 diabetes.

16 Jan 2014

Research findings may offer new way to treat prion diseases

New research from David Westaway, PhD, of the University of Alberta and Jiri Safar, PhD, Case Western Reserve University School of Medicine has uncovered a quality control mechanism in brain cells that may help keep deadly neurological diseases in check for months or years.

16 Jan 2014

Heavy drinking associated with faster decline in cognitive function in middle-aged men

Middle-aged men who drink more than 36 grams of alcohol, or two and a half US drinks per day, may speed their memory loss by up to six years later on, according to a study published in the January 15, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology.

16 Jan 2014

Cognigram can detect early signs of MCI and Alzheimer’s disease

For patients over the age of 50, a routine physical exam at the doctor’s office typically covers a wide spectrum of medical biomarkers with one glaring exception, cognitive health. Unless there have been unusual mental changes or challenges in their daily life, tests of a patient’s attention, memory or brain processing speed is usually not part of a check-up.

15 Jan 2014

Presence of gene variant in people with MCI associated with accelerated rates of brain atrophy

The presence of a gene variant in people with mild cognitive impairment is associated with accelerated rates of brain atrophy, according to a new study published online in the journal Radiology.

15 Jan 2014

Ultrasound can modulate brain activity to heighten sensory perception in humans

Whales, bats, and even praying mantises use ultrasound as a sensory guidance system - and now a new study has found that ultrasound can modulate brain activity to heighten sensory perception in humans.

13 Jan 2014

At-home paper test can help spot early symptoms of cognitive issues

The Self-Administered Gerocognitive Examination (SAGE test), which takes less than 15 minutes to complete, is a reliable tool for evaluating cognitive abilities. Findings by researchers at The Ohio State University Wexner Medical Center confirming the feasibility and efficiency of the tool for community screening large numbers of people are published in the January issue of The Journal of Neuropsychiatry and Clinical Neurosciences.

13 Jan 2014

Researchers discover two genetic mutations associated with Familial Alzheimer's Disease

New research, led by Rensselaer Polytechnic Institute researcher Chunyu Wang, has solved one mystery in the development of Familial Alzheimer's Disease (FAD), a genetic variant of the disease that affects a small fraction of the Alzheimer's population. In a paper published online January 6 in the journal Nature Communications, Wang and his team follow the trail of two genetic mutations - V44M and V44A - known to cause FAD, and show how the mutations lead to biochemical changes long linked to the disease.

13 Jan 2014

New technology efficiently transfers investigational antibodies from blood via blood-brain barrier

Today the scientific journal Neuron published results on the Roche-designed Brain Shuttle technology that efficiently transfers investigational antibodies from the blood through the blood-brain barrier (BBB) into the brain in preclinical models.

10 Jan 2014

Biogen Idec, Sangamo BioSciences partner to develop therapeutics for hemoglobinopathies

Biogen Idec and Sangamo BioSciences, Inc. announced today an exclusive worldwide collaboration and license agreement focused on the development of therapeutics for hemoglobinopathies, inherited conditions that result from the abnormal structure or underproduction of hemoglobin.

9 Jan 2014

NYSCF and ISMMS scientists successfully generate stem cell model of familial Alzheimer's disease

Scientists at The New York Stem Cell Foundation Research Institute in collaboration with scientists at the Icahn School of Medicine at Mount Sinai successfully generated a stem cell model of familial Alzheimer's disease.

8 Jan 2014

Epilepsy drug taken during pregnancy not linked with development problems for preschoolers

A new study finds that the epilepsy drug levetiracetam appears not to be associated with thinking, movement and language problems for preschool children born to mothers who took the drug during pregnancy, although the drug valproate was associated with some difficulties in preschoolers.

8 Jan 2014

Slower decline for patients with PARKIN-associated PD

Cognitive and motor decline may be slower in patients with early-onset Parkinson’s disease if they have PARKIN mutations, suggests an analysis of the Consortium on Risk for Early-Onset PD study.

8 Jan 2014

Dementia detracts from PD patients’ life expectancy

Patients with Parkinson’s disease have an increased risk for mortality, especially if they have dementia, a meta-analysis confirms.

8 Jan 2014

Study links racism-related factors and biological aging among African American men

A new study reveals that racism may impact aging at the cellular level. Researchers found signs of accelerated aging in African American men, ages reporting high levels of racial discrimination and who had internalized anti-Black attitudes.

8 Jan 2014

Scientists believe that new links between brain cells help encode new memories and skills

In adults, some brain regions retain a "childlike" ability to establish new connections, potentially contributing to our ability to learn new skills and form new memories as we age, according to new research from Washington University School of Medicine in St. Louis and the Allen Institute for Brain Science in Seattle.

8 Jan 2014

Study shows ability to make living human cells from biobanked brain tissue of Alzheimer's patients

Scientists at The New York Stem Cell Foundation (NYSCF) Research Institute, working in collaboration with scientists from Columbia University Medical Center (CUMC), for the first time generated induced pluripotent stem (iPS) cells lines from non-cryoprotected brain tissue of patients with Alzheimer's disease.

7 Jan 2014

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Researcher finds possible way to unravel misfolded proteins by reprogramming yeast protein

Research uncovers new mechanism in brain cells that may help keep deadly neurological diseases in check

Higher vitamin D levels linked with better cognition and less depression in PD patients

Study explores the role of DNA in predisposing individuals to diseases

Research findings may offer new way to treat prion diseases

Heavy drinking associated with faster decline in cognitive function in middle-aged men

Cognigram can detect early signs of MCI and Alzheimer’s disease

Presence of gene variant in people with MCI associated with accelerated rates of brain atrophy

Ultrasound can modulate brain activity to heighten sensory perception in humans

At-home paper test can help spot early symptoms of cognitive issues

Researchers discover two genetic mutations associated with Familial Alzheimer's Disease

New technology efficiently transfers investigational antibodies from blood via blood-brain barrier

Biogen Idec, Sangamo BioSciences partner to develop therapeutics for hemoglobinopathies

NYSCF and ISMMS scientists successfully generate stem cell model of familial Alzheimer's disease

Epilepsy drug taken during pregnancy not linked with development problems for preschoolers

Slower decline for patients with PARKIN-associated PD

Dementia detracts from PD patients’ life expectancy

Study links racism-related factors and biological aging among African American men

Scientists believe that new links between brain cells help encode new memories and skills

Study shows ability to make living human cells from biobanked brain tissue of Alzheimer's patients

Innovation in neuroscience drug discovery - eBook eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Innovation in neuroscience drug discovery - eBook eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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