Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

TSG might be novel compound for treatment of Alzheimer's and dementia with Lewy body

Administration of the active compound tetrahydroxystilbene glucoside (TSG) derived from the Chinese herbal medicine Polygonum multiflorum Thunb, reversed both overexpression of α-synuclein, a small protein found in the brain, and its accumulation using a mouse model of Alzheimer's disease.

16 Feb 2013

Tau release from healthy neurons can be regulated by neuronal activity

Researchers from King's College London have discovered that neuronal activity can stimulate tau release from healthy neurons in the absence of cell death.

16 Feb 2013

First Edition: February 15, 2013

Today's headlines include news about how the health law's insurance exchanges are taking shape.

15 Feb 2013

Protein-restricted diet supplemented with IGF-I may protect from Alzheimer's

Mice with many of the pathologies of Alzheimer's Disease showed fewer signs of the disease when given a protein-restricted diet supplemented with specific amino acids every other week for four months.

15 Feb 2013

Targacept reports net loss of $15.9 million for fourth quarter 2012

Targacept, Inc., a clinical-stage biopharmaceutical company developing novel NNR Therapeutics, today reported its financial results for the fourth quarter and year ended December 31, 2012.

14 Feb 2013

Study demonstrates how CN2097 works to restore neural functions impaired by Angelman syndrome

In a new study in mice, a scientific collaboration centered at Brown University lays out in unprecedented detail a neurological signaling breakdown in Angelman syndrome, a disorder that affects thousands of children each year, characterized by developmental delay, seizures, and other problems.

14 Feb 2013

Antibody therapeutics targeting GPCRs to be developed by alliance between MorphoSys and Heptares

MorphoSys AG (FSE: MOR; Prime Standard Segment, TecDAX) and UK-based Heptares Therapeutics, the leading GPCR drug discovery and development company, have signed an agreement to discover novel antibody therapeutics targeting G protein-coupled receptors (GPCRs), which are membrane proteins involved in a broad range of biological processes and diseases.

13 Feb 2013

Study finds abnormal production of C9RANT in patients with ALS, frontotemporal dementia

Researchers at Mayo Clinic have discovered an abnormal protein that accumulates in the brains of many patients affected with two common neurodegenerative disorders — amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig's disease, and frontotemporal dementia.

13 Feb 2013

Boston College biologist receives $2.7M NIH grant to continue HIV and AIDS research

Boston College biologist Ken Williams, whose research focuses on the role of immunological cells in a range of illnesses that strike people living with HIV and AIDS, has been awarded a five-year, $2.7 million grant from the NIH's National Institute of Neurological Disorders and Stroke.

12 Feb 2013

Brookdale fourth quarter total revenue increases 4.1% to $699.7 million

Brookdale Senior Living Inc. today reported financial and operating results for the fourth quarter and full year 2012.

11 Feb 2013

Scientists identify enigmatic aggregates linked to neurodegenerative diseases

The proteins that have now been identified shouldn't actually exist. Nevertheless, they build the core of cellular aggregates whose identity has been enigmatic until now. These aggregates are typically associated with hereditary neurodegenerative diseases including variants of frontotemporal dementia (FTD), also known as frontotemporal lobar degeneration (FTLD), and amyotrophic lateral sclerosis (ALS). They are likely to be damaging and might be a target for therapy.

11 Feb 2013

Four-month instructional dance program can improve health of Latino seniors

Vigorous activity can improve the physical and mental health of older adults, but for many, particularly Latinos, exercise is not a regular part of their lives, according to a University of Illinois at Chicago researcher.

11 Feb 2013

Experts discuss hottest topics in Alzheimer's brain imaging at 7th HAI conference

At the 7th Human Amyloid Imaging conference held last month in Miami, Florida, 250 experts discussed the hottest topics in Alzheimer's disease brain imaging.

11 Feb 2013

FDA issues draft guidance on developing new treatments for Alzheimer's

Today, the U.S. Food and Drug Administration issued a proposal designed to assist companies developing new treatments for patients in the early stages of Alzheimer's disease, before the onset of noticeable (overt) dementia.

11 Feb 2013

Report: The number of Americans with Alzheimer's disease will almost triple by 2050

The government-funded report projects the Alzheimer's cases will rise from 5 million to about 13.8 million, thereby straining the nation's health care system.

10 Feb 2013

Roundup: Assisted suicide legalization urged; Abortion bill tensions in Wash., Ore.; Budget squeezes in Ga., Conn.

A push for the legalization of physician-assisted suicide is under way in a half-dozen states where proponents say they see strong support for allowing doctors to prescribe mentally competent, dying individuals with the medications needed to end their own lives. ... Groups such as Compassion & Choices, a national end-of-life advocacy organization, have been working to advance the cause.

10 Feb 2013

Drugs that target retromer pathway could help prevent or treat Parkinson's

Columbia University Medical Center (CUMC) researchers have identified a protein trafficking defect within brain cells that may underlie common non-familial forms of Parkinson's disease.

9 Feb 2013

Academic medical centers play an integral role in developing new treatments and cures

As an internationally recognized researcher into aging and dementia, Suzanne Craft is keenly aware of the importance of volunteers in clinical studies.

9 Feb 2013

Alzheimer's appears to be on the rise

The number of people with Alzheimer's disease is expected to triple in the next 40 years, according to a new study by researchers from Rush University Medical Center published in the February 6, 2013, online issue of Neurology, the medical journal of the American Academy of Neurology.

9 Feb 2013

Nerve stimulator may be new option for migraine sufferers

Wearing a nerve stimulator for 20 minutes a day may be a new option for migraine sufferers, according to new research published in the February 6, 2013, online issue of Neurology, the medical journal of the American Academy of Neurology.

9 Feb 2013

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

TSG might be novel compound for treatment of Alzheimer's and dementia with Lewy body

Tau release from healthy neurons can be regulated by neuronal activity

First Edition: February 15, 2013

Protein-restricted diet supplemented with IGF-I may protect from Alzheimer's

Targacept reports net loss of $15.9 million for fourth quarter 2012

Study demonstrates how CN2097 works to restore neural functions impaired by Angelman syndrome

Antibody therapeutics targeting GPCRs to be developed by alliance between MorphoSys and Heptares

Study finds abnormal production of C9RANT in patients with ALS, frontotemporal dementia

Boston College biologist receives $2.7M NIH grant to continue HIV and AIDS research

Brookdale fourth quarter total revenue increases 4.1% to $699.7 million

Scientists identify enigmatic aggregates linked to neurodegenerative diseases

Four-month instructional dance program can improve health of Latino seniors

Experts discuss hottest topics in Alzheimer's brain imaging at 7th HAI conference

FDA issues draft guidance on developing new treatments for Alzheimer's

Report: The number of Americans with Alzheimer's disease will almost triple by 2050

Roundup: Assisted suicide legalization urged; Abortion bill tensions in Wash., Ore.; Budget squeezes in Ga., Conn.

Drugs that target retromer pathway could help prevent or treat Parkinson's

Academic medical centers play an integral role in developing new treatments and cures

Alzheimer's appears to be on the rise

Nerve stimulator may be new option for migraine sufferers

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

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