Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

GSA, NAM select 16 reporters for MetLife Foundation Journalists in Aging Fellows Program

The Gerontological Society of America (GSA) and New America Media (NAM) have selected 16 reporters for the MetLife Foundation Journalists in Aging Fellows Program, now in its second year.

30 Sep 2011

AstraZeneca settles SEROQUEL XR patent infringement litigation

AstraZeneca today announced it has entered into a settlement agreement in its U.S. SEROQUEL XR patent infringement litigation against Handa Pharmaceuticals, LLC regarding Handa's proposed generic version of AstraZeneca's SEROQUEL XR extended-release tablets.

30 Sep 2011

Intensive blood glucose control therapy provides no added benefit against cognitive decline in older diabetics

Intensive control of blood sugar levels beyond standard targets provides no additional protection against cognitive decline in older people with diabetes than standard treatment, according to a national study coordinated by researchers at Wake Forest Baptist Medical Center.

29 Sep 2011

Researchers discover kibra protein controls sculpting of brain circuitry

Researchers working with adult mice have discovered that learning and memory were profoundly affected when they altered the amounts of a certain protein in specific parts of the mammals' brains.

29 Sep 2011

New report finds little evidence to support off-label use of atypical antipsychotics

There is little evidence to support the use of atypical antipsychotic drugs for some treatments other than their officially approved purposes, even though many clinicians continue to commonly prescribe these drugs for so-called "off label" uses, according to a new report from the U.S. Department of Health and Human Services' (HHS) Agency for Healthcare Research and Quality.

29 Sep 2011

Prehypertension may increase risk of stroke

Even people with blood pressure that is slightly above normal may be at an increased risk of stroke, according to a review of studies published in the September 28, 2011, online issue of Neurology, the medical journal of the American Academy of Neurology.

29 Sep 2011

Older women destined to develop AD have high blood levels of pregnancy protein

In an advance toward a much-needed early diagnostic test for Alzheimer's disease (AD), scientists have discovered that older women destined to develop AD have high blood levels of a protein linked to pregnancy years before showing symptoms.

29 Sep 2011

Congress must not make cuts to crucial government-funded aging research

America's experts on aging are headed for meetings with their senators and representatives to underscore the needs of the country's senior population, spurred by the first-ever Take Action Week organized by The Gerontological Society of America - the nation's largest interdisciplinary organization devoted to the field of aging.

28 Sep 2011

Adamas begins ADS-5102 Phase 2/3 clinical trial in Parkinson's disease

Adamas Pharmaceuticals, Inc., a privately held company, announced today that it has initiated a Phase 2/3 clinical trial of its proprietary investigational drug ADS-5102 (amantadine HCl extended release) for the treatment of levodopa induced dyskinesia (LID) in patients with Parkinson's disease.

28 Sep 2011

Benefits and harms vary among atypical antipsychotics for off-label use

A review of previous studies suggests that even though atypical antipsychotic medications are commonly used for off-label conditions such as behavioral symptoms of dementia, anxiety, and obsessive-compulsive disorder, these medications are effective for only a few off-label conditions, and that the benefits and harms of these medications for these uses vary, according to an article in the September 28 issue of JAMA.

28 Sep 2011

Low vitamin B12 raises risk of dementia in the elderly: Study

According to a latest study the elderly with low levels of vitamin B12 in their blood may be more likely to develop problems with their thinking skills and have more brain shrinkage. The study points to a link between low B12 and early cognitive decline, a condition that often leads to dementia. Previous research has found that those people with high levels of vitamin B12 in their blood have lower levels of an amino acid called homocysteine, which some studies have linked to an increased risk of Alzheimer's disease, memory loss, and stroke.

27 Sep 2011

NYU Langone to lead NVVLS on long-term effects of PTSD

NYU Langone Medical Center announced that Charles R. Marmar, MD, the Lucius N. Littauer Professor of Psychiatry and chair of the Department of Psychiatry, was selected to lead the clinical evaluation component of a national survey — the National Vietnam Veterans Longitudinal Study (NVVLS) — on the long-term effects of combat-related post-traumatic stress disorder (PTSD) and other related health conditions on Vietnam veterans.

27 Sep 2011

Prenatal exercise improves brain plasticity and prevents Alzheimer's in offspring

If you are pregnant, here's another reason to work out: you will reduce the chances of your new baby developing neurodegenerative diseases, such as Alzheimer's, later in life.

27 Sep 2011

Vitamin B12 deficiency linked to cognitive problems or loss in brain volume among older people

Older people with low levels of vitamin B12 in their blood may be more likely to lose brain cells and develop problems with their thinking skills, according to a study published in the September 27, 2011, print issue of Neurology, the medical journal of the American Academy of Neurology.

27 Sep 2011

NINDS award to fund studies of Arizonans with Parkinson's disease

The National Institute of Neurological Disorders and Stroke (NINDS) announced this week an $8 million, five-year grant to support a "National Brain and Tissue Resource for Parkinson's Disease and Related Disorders", awarded to Banner Sun Health Research Institute (BSHRI) and Mayo Clinic Arizona.

26 Sep 2011

Researchers identify micro-RNA that regulates learning processes, Alzheimer's

Proteins are the molecular machines of the cell. They transport materials, cleave products or transmit signals - and for a long time, they have been a main focus of attention in molecular biology research. In the last two decades, however, another class of critically important molecules has emerged: small RNA molecules, including micro-RNAs. It is now well established that micro-RNAs play a key role in the regulation of cell function."A micro-RNA regulates the production of an estimated 300-400 proteins.

26 Sep 2011

Two TGen students receive SRP grants for antibiotic resistance and Alzheimer's research

Two Arizona university graduate students working at the Translational Genomics Research Institute (TGen) have each received $50,000 grants from the Salt River Project.

23 Sep 2011

CoPlex, Hawthorn sign license agreement for hawAD14 Alzheimer's drug

CoPlex Therapeutics has signed an exclusive global license agreement with Hawthorn Pharmaceuticals to develop and commercialize hawAD14, a preclinical oral small molecule candidate for the treatment of Alzheimer's and other neurodegenerative diseases.

23 Sep 2011

Cyclin E plays a crucial role in the formation of nerve connections

Scientists at Dana-Farber Cancer Institute and Harvard Medical School have found that a common cancer protein leads a second, totally different life in normal adult brain cells: It helps regulates memory formation and may be implicated in Alzheimer's disease.

23 Sep 2011

Dementia patients have poor outcomes in hospital

If you have dementia and need to be admitted to hospital to be treated for other illnesses or injuries, your prospects for recovery are substantially worse than for other patients, research has found.

22 Sep 2011

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

GSA, NAM select 16 reporters for MetLife Foundation Journalists in Aging Fellows Program

AstraZeneca settles SEROQUEL XR patent infringement litigation

Intensive blood glucose control therapy provides no added benefit against cognitive decline in older diabetics

Researchers discover kibra protein controls sculpting of brain circuitry

New report finds little evidence to support off-label use of atypical antipsychotics

Prehypertension may increase risk of stroke

Older women destined to develop AD have high blood levels of pregnancy protein

Congress must not make cuts to crucial government-funded aging research

Adamas begins ADS-5102 Phase 2/3 clinical trial in Parkinson's disease

Benefits and harms vary among atypical antipsychotics for off-label use

Low vitamin B12 raises risk of dementia in the elderly: Study

NYU Langone to lead NVVLS on long-term effects of PTSD

Prenatal exercise improves brain plasticity and prevents Alzheimer's in offspring

Vitamin B12 deficiency linked to cognitive problems or loss in brain volume among older people

NINDS award to fund studies of Arizonans with Parkinson's disease

Researchers identify micro-RNA that regulates learning processes, Alzheimer's

Two TGen students receive SRP grants for antibiotic resistance and Alzheimer's research

CoPlex, Hawthorn sign license agreement for hawAD14 Alzheimer's drug

Cyclin E plays a crucial role in the formation of nerve connections

Dementia patients have poor outcomes in hospital

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Reducing polypharmacy through innovative drug formulation technologies

How innovation in dried blood spot testing is transforming neurological disease monitoring

Unlocking live single-cell functional insights

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Reducing polypharmacy through innovative drug formulation technologies

How innovation in dried blood spot testing is transforming neurological disease monitoring

Unlocking live single-cell functional insights

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