Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Study identifies monoacylglycerol lipase as new therapeutic target to treat Alzheimer's

Research led by Chu Chen, PhD, Associate Professor of Neuroscience at LSU Health Sciences Center New Orleans, has identified an enzyme called Monoacylglycerol lipase (MAGL) as a new therapeutic target to treat or prevent Alzheimer's disease.

2 Nov 2012

Blocking hyaluronidase activity can help repair brain damage associated with MS

Researchers at Oregon Health & Science University have discovered that blocking a certain enzyme in the brain can help repair the brain damage associated with multiple sclerosis and a range of other neurological disorders.

1 Nov 2012

Additional data from EnVivo’s EVP-6124 Phase 2b trial on AD presented at CTAD meeting

EnVivo Pharmaceuticals, a company dedicated to developing a broad range of novel central nervous system (CNS) therapies, today presented pharmacokinetic and pharmacodynamic data along with the previously reported statistically significant clinical results from its Phase 2b clinical trial of EVP-6124, a novel alpha-7 agonist, in patients with Alzheimer's disease.

1 Nov 2012

Integra Holdings, a biopharmaceutical holding company, announced by Yissum

Yissum Research and Development Company of the Hebrew University of Jerusalem, the technology transfer company of the Hebrew University, announced today the inception of its subsidiary, Integra Holdings, a holding company focusing on biopharmaceutical companies based on inventions of researchers from the Hebrew University.

31 Oct 2012

FDA accepts Sunovion’s two LATUDA sNDAs for review

Sunovion Pharmaceuticals Inc. today announced that the U.S. Food and Drug Administration (FDA) has accepted for review two supplemental New Drug Applications (sNDAs) for the use of LATUDA as 1) monotherapy and 2) adjunctive therapy to lithium or valproate, both to treat adult patients with depressive episodes associated with bipolar I disorder (bipolar depression).

31 Oct 2012

Intravenous catheter replacement: an interview with Claire Rickard

Peripheral intravenous catheters (“IV drips”) are small plastic tubes inserted into veins, most frequently in the hand or arm.

30 Oct 2012

Children with migraine more likely to have below average school performance

Children with migraine are more likely to have below average school performance than kids who do not have headaches, according to new research published in the October 30, 2012, print issue of Neurology-, the medical journal of the American Academy of Neurology.

30 Oct 2012

TTP488 slows cognitive decline in patients with mild to moderate Alzheimer's

A novel, orally administered drug candidate, TTP488, has demonstrated clinical evidence of slowing of cognitive decline over 18 months of therapy in patients with mild to moderate Alzheimer's disease.

30 Oct 2012

Notable Medicare lawsuit settlement could aid patients needing skilled nursing care, other types of therapy

News outlets explain how a recent Medicare settlement could have an important impact on people who need physical, occupational and other therapies for certain disabilities and chronic conditions.

30 Oct 2012

Stay active to keep a healthy mind in very old age

Poor physical performance, especially a slow walking speed, is significantly associated with dementia in individuals aged over 90 years, show study results.

29 Oct 2012

First Edition: October 29, 2012

Today's headlines include reports about how the presidential election's outcome could impact the insurance industry as well as the fate of people who are sick or uninsured.

29 Oct 2012

Scientists identify grid cells in the brains of rhesus monkeys

Primates' brains see the world through triangular grids, according to a new study published online Sunday in the journal Nature.

29 Oct 2012

Researchers discover that bean commonly used in Chinese cuisine protects against sepsis

Researchers at The Feinstein Institute for Medical Research have discovered that a bean commonly used in Chinese cuisine protects against the life-threatening condition sepsis.

29 Oct 2012

Study demonstrates role of IRX4204 in alleviating cognitive decline in animal models of AD

New research presented in October at the 6th Neurodegenerative Conditions Research and Development Conference in San Francisco demonstrates the role of the investigational compound IRX4204 in alleviating cognitive decline in animal models of Alzheimer's disease (AD).

29 Oct 2012

Mouse model may provide clues on mechanism that links diabetes and aging to Alzheimer's

Growing evidence suggests that there may be a link between diabetes and Alzheimer's disease, but the physiological mechanisms by which diabetes impacts brain function and cognition are not fully understood. In a new study published in Aging Cell, researchers at the Salk Institute for Biological Studies show, for the first time, that diabetes enhances the development of aging features that may underlie early pathological events in Alzheimer's.

29 Oct 2012

Study describes how Dbr1 gene halts toxic buildup of TDP-43-a protein

Scientists at the Gladstone Institutes and the Stanford University School of Medicine have discovered how modifying a gene halts the toxic buildup of a protein found in nerve cells. These findings point to a potential new tactic for treating a variety of neurodegenerative conditions, including amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease)-a fatal disease for which there is no cure.

29 Oct 2012

ApoE4 gene becomes less important to quality of life once people hit their 90s

A gene linked to the risk of developing Alzheimer's, heart disease and diabetes becomes less important to quality of life once people hit their 90s, a Mayo Clinic study shows. At that point, good friends and a positive attitude have a bigger impact, the researchers say.

26 Oct 2012

Feinstein Institute to study overall impact of WTC disaster on responders

The Feinstein Institute for Medical Research has been awarded a $1 million grant from the World Trade Center Health Program, which is administered by the National Institute for Occupational Safety and Health, part of the US Centers for Disease Control and Prevention, the National Institute for Occupational Safety and Health and Safety to comprehensively study the overall physical, mental and socioeconomic impact of the World Trade Center (WTC) disaster on responders, as well as identify the linkage between socioeconomic status and health among all occupations of WTC responders.

26 Oct 2012

Three new gene variants associated with BMI levels in adults

A large international study has identified three new gene variants associated with body mass index (BMI) levels in adults. The scientific consortium, numbering approximately 200 researchers, performed a meta-analysis of 46 studies, covering gene data from nearly 109,000 adults, spanning four ethnic groups.

26 Oct 2012

Anterior insular cortex associated with human empathy

An international team led by researchers at Mount Sinai School of Medicine in New York has for the first time shown that one area of the brain, called the anterior insular cortex, is the activity center of human empathy, whereas other areas of the brain are not. The study is published in the September 2012 issue of the journal Brain.

25 Oct 2012

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Study identifies monoacylglycerol lipase as new therapeutic target to treat Alzheimer's

Blocking hyaluronidase activity can help repair brain damage associated with MS

Additional data from EnVivo’s EVP-6124 Phase 2b trial on AD presented at CTAD meeting

Integra Holdings, a biopharmaceutical holding company, announced by Yissum

FDA accepts Sunovion’s two LATUDA sNDAs for review

Intravenous catheter replacement: an interview with Claire Rickard

Children with migraine more likely to have below average school performance

TTP488 slows cognitive decline in patients with mild to moderate Alzheimer's

Notable Medicare lawsuit settlement could aid patients needing skilled nursing care, other types of therapy

Stay active to keep a healthy mind in very old age

First Edition: October 29, 2012

Scientists identify grid cells in the brains of rhesus monkeys

Researchers discover that bean commonly used in Chinese cuisine protects against sepsis

Study demonstrates role of IRX4204 in alleviating cognitive decline in animal models of AD

Mouse model may provide clues on mechanism that links diabetes and aging to Alzheimer's

Study describes how Dbr1 gene halts toxic buildup of TDP-43-a protein

ApoE4 gene becomes less important to quality of life once people hit their 90s

Feinstein Institute to study overall impact of WTC disaster on responders

Three new gene variants associated with BMI levels in adults

Anterior insular cortex associated with human empathy

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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