Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Functional genomics provide improved drug discovery

Functional genomics and proteomics have been quite successful in identifying functions of potential therapeutic targets such as encoded proteins.

20 Apr 2004

Myriad Genetics advances drug for chemotherapy-induced nausea

Myriad Genetics, Inc. today released new data on MPC-4505, its Neurokinin-1 (NK1) receptor antagonist, a drug candidate for chemotherapy-induced nausea and vomiting (emesis). MPC-4505 is a potent, orally bioavailable, CNS-penetrating, highly selective NK1 antagonist.

20 Apr 2004

Jefferson scientists learn how HIV causes dementia

Ever since the AIDS epidemic began more than two decades ago, scientists have been trying to understand why as many as one-quarter of those infected with HIV develop dementia.

19 Apr 2004

Curry offers possible protection against Alzheimer’s disease

A new study has found that curry, a common and popular cooking additive, could be an effective enhancer of an enzyme that protects the brain against oxidative conditions.

19 Apr 2004

Omega-3 fatty acids found in seafood improve brain function

Citing new evidence that the omega-3 fatty acids found in seafood improve brain function in middle aged people and actually lower the risk of mental impairment as people age, the U.S. Tuna Foundation (USTF) today reminded the public that canned tuna is not only good for your heart but is a tasty and affordable "brain food" for people of all ages.

17 Apr 2004

Alzheimer Association responds to April 16 Wall Street Journal article

Dear Editor: Scientists World-Wide Battle a Narrow View of Alzheimer’s Cause, incorrectly implies Alzheimer science is headed down a blind alley. The real issue is inadequate funding.

16 Apr 2004

Delirium in ICU patients a predictor of mortality

Between 60 percent to 80 percent of these patients develop a brain dysfunction known as delirium, which according to a group of physicians at Vanderbilt Medical Center is an independent predictor of mortality.

16 Apr 2004

Possible new treatment strategy for Alzheimer's disease

A new study in mice identifies one of the missing steps in how Alzheimer's develops and suggests a possible new treatment strategy, according to researchers at Columbia University Medical Center and Weill Cornell Medical College and their colleagues.

16 Apr 2004

Scientists discover gene for Parkinson's disease

UCL scientists have discovered a new gene implicated in the early development of Parkinson's disease. In a study of families with early onset disease, Professor Nick Wood and colleagues at University College London's Institute of Neurology identified a novel gene which produces a malfunctioning protein that could pave the way for new treatments for Parkinson sufferers.

16 Apr 2004

Liptor helps Alzheimer’s disease

In a small clinical trial enrolling 63 individuals with Alzheimer’s disease, half of those who received atorvastatin (Lipitor) stabilized or improved after one year of treatment, the trial’s principal investigator D. Larry Sparks, Ph.D., reported today at a professional meeting on Alzheimer therapy.

15 Apr 2004

Women get better picture on hormone replacement therapy

Detailed results of the "estrogen-alone" study within the Women's Health Initiative (WHI), which was terminated in early March 2004, are providing some of the first answers to questions about the efficacy of estrogen alone to prevent chronic disease in healthy, postmenopausal women who have had a hysterectomy.

14 Apr 2004

Cinnamon's role as an insulin substitute in type II diabetes

Cinnamon may be more than a spice – it may have a medical application in preventing and combating diabetes. Cinnamon may help by playing the role of an insulin substitute in type II diabetes, according to cellular and molecular studies at the University of California, Santa Barbara, Iowa State University and the U.S. Department of Agriculture.

14 Apr 2004

Alzheimer fact sheet released

Dementia is a syndrome consisting of a number of symptoms that include loss of memory, judgment and reasoning, and changes in mood, behaviour and communication abilities. Alzheimer Disease, the most common form of dementia, accounts for 64 per cent of all dementias in Canada.

14 Apr 2004

Estrogen-alone hormone therapy had no effect on coronary heart disease risk

A large, multi-center heart disease prevention study, part of the Women's Health Initiative (WHI), found that estrogen-alone hormone therapy had no effect on coronary heart disease risk but increased the risk of stroke for postmenopausal women.

13 Apr 2004

Vitamin C can reduce levels of C-reactive protein, a marker of inflammation and chronic disease

Vitamin C supplements can reduce levels of C-reactive protein, a marker of inflammation and chronic disease risk in humans, according to a new study led by researchers at the University of California, Berkeley.

12 Apr 2004

A protein involved in the release of neurotransmitters in the brain is essential to learning and memory

A study published today in Neuron offers the first evidence that lack of this protein - known as RIM1 alpha - causes profound deficits in the learning process. The discovery is a major step in understanding the molecular events that underlie learning and memory - complex processes that can be impaired in human neuropsychiatric disorders such as Alzheimer's disease, mental retardation and schizophrenia.

7 Apr 2004

Alzheimer's live about half as long as those of similar age without dementia

Age, seriousness of impairment, and the severity of other medical conditions are important indicators of how long an individual might survive after an Alzheimer's disease diagnosis, Eric B. Larson, M.D., M.P.H. and colleagues report in the April 6 Annals of Internal Medicine. Study authors include Linda Teri, Ph.D., recipient of an Alzheimer's Association $1 million Pioneer research grant.

6 Apr 2004

Study Identifies Predictors of Alzheimer's Disease Longevity

It's among the first questions asked after someone is diagnosed with Alzheimer's disease: "What can we expect?" It's a tough question that has been difficult to answer. But a new study suggests that assessing several key clinical aspects of the disease soon after diagnosis could help families and physicians better predict long-term survival in individuals with AD.

6 Apr 2004

Common cholinesterase inhibitor eases behavioral symptoms like agitation, depression, and psychosis in patients

The so-called "memory drugs" used to treat Alzheimer's disease and other causes of dementia also ease or prevent a barrage of troublesome behaviors that affect the majority of patients, ultimately lightening the burden on caregivers, researchers have found. They report their results in the March issue of the American Journal of Psychiatry.

5 Apr 2004

Alzheimer’s Association asks for $40 million in additional funding

The Alzheimer’s Association today called on the House of Representatives to provide $40 million in additional funding this year to the National Institutes of Health NIH) to support large-scale clinical trials for treatments that would slow or delay the progression of Alzheimer’s disease.

30 Mar 2004