Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Discovery of shared biological properties among DNA variants may help identify new therapeutic targets

The discovery of shared biological properties among independent variants of DNA sequences offers the opportunity to broaden understanding of the biological basis of disease and identify new therapeutic targets, according to a collaboration between the Perelman School of Medicine at the University of Pennsylvania, the University of Arizona Health Sciences, and Vanderbilt University. The group published their findings this month in npj Genomic Medicine.

29 Apr 2016

TSRI study reveals important traits in LCMV, Lassa virus

For the first time, scientists at The Scripps Research Institute (TSRI) have solved the structure of the biological machinery used by a common virus to recognize and attack human host cells.

27 Apr 2016

Study shows canine AD shares significant features of human version

Atopic dermatitis (AD), a chronic inflammatory skin condition and the most common form of eczema, is estimated to afflict as much as 10 percent of the U.S. population, and is much more common now than it was 50 years ago. Veterinary clinical estimates also show that approximately 10 percent of dogs have atopic dermatitis.

26 Apr 2016

RA patients more likely to experience hearing loss

RA is the commonest autoimmune arthritis affecting 1% of the general population. Despite its main articular manifestations, RA caninvolveextra-articular organs including the auditory system.

25 Apr 2016

Wellderly study finds link between cognitive decline genes and healthy aging

An eight-year-long accrual and analysis of the whole genome sequences of healthy elderly people, or "Wellderly," has revealed a higher-than-normal presence of genetic variants offering protection from cognitive decline, researchers from the Scripps Translational Science Institute (STSI) reported today in the journal Cell.

22 Apr 2016

Study indicates that resolvin D1 has anti-arthritic properties

Rheumatoid arthritis (RA) is a debilitating autoimmune disorder that is characterized by the accumulation of inflammatory cells within the fluid of the joints. Current therapeutic strategies mostly serve to ease pain and rarely are able to reverse damage or resolve inflammation.

22 Apr 2016

Non-invasive optogenetic therapy can help treat chronic pain

The potential of light as a non-invasive, highly-focused alternative to pain medication was made more apparent thanks to research conducted by scientists at the Montreal Neurological Institute and Hospital of McGill University and the McGill University Health Centre.

21 Apr 2016

Therapies based on alpha defensins could help treat rheumatoid arthritis

Arthritis and other inflammatory conditions could be helped by new insights into how the immune response is switched off.

19 Apr 2016

MGH-led study confirms safety of allergy immunotherapy

A team of Massachusetts General Hospital investigators has found no evidence of infections related to administration of allergy immunotherapy, the common practice of injecting minimal quantities of allergens beneath the skin to reduce the allergic response.

18 Apr 2016

Study supports screening for HLA-B*5801 gene variant in Asian, black patients with gout

A multi-institutional study led by a Massachusetts General Hospital investigator finds significant racial disparities in the risk that patients being treated for gout will develop a serious, sometimes life-threatening adverse reaction to the most commonly prescribed medication. The increased risk closely correlates with the frequency of a gene variant previously associated with that adverse reaction, supporting recommendations to screen for that variant in patients from those populations.

16 Apr 2016

Intestinal bacteria can be used to reduce cancer risk, reveals UCLA study

Researchers have shown that various types of intestinal bacteria might be factors in both causing and preventing obesity, and in other conditions and diseases. Now, a UCLA study suggests that it could also potentially be used to reduce the risk for some types of cancer.

16 Apr 2016

Taking antibiotics in early childhood can disrupt immune system function lifelong

Scientists want to know whether taking antibiotics early in life can disrupt your immune system function lifelong.

15 Apr 2016

M10 peptide could help protect systemic sclerosis patients against fibrotic damage

The results of preclinical studies by investigators at the Medical University of South Carolina (MUSC) reported in the April 2016 issue of Translational Research suggest that the M10 peptide could help protect against fibrotic damage in patients with systemic sclerosis, particularly in those who develop interstitial lung diseases (ILD), its deadliest complication.

15 Apr 2016

Tips to help treat corns and calluses

Ever wonder what causes corns and calluses? According to dermatologists from the American Academy of Dermatology, these hard, thickened areas of skin form as a result of friction or pressure on the skin. In fact, they say, corns and calluses develop naturally to help protect the skin underneath them.

13 Apr 2016

Carbohydrate-binding protein controls inflammation in osteoarthritis patients

More and more people, particularly older people, are suffering from osteoarthritis due to wear and tear on their joints. This primarily affects the knee and hip joints but also the spine. In earlier studies, scientists at MedUni Vienna Department of Orthopaedics showed that raised levels of certain proteins, so-called galectins, and their docking sites are found in patients with osteoarthritis.

7 Apr 2016

Researchers develop mouse model for testing vaccines, therapeutics to battle Zika virus

A research team at Washington University School of Medicine in St. Louis has established a mouse model for testing of vaccines and therapeutics to battle Zika virus.

6 Apr 2016

Young arthritis patients have concerns about consequences arising from treatment

A new study funded by Arthritis Research UK indicates that teens and young adults with inflammatory arthritis see treatment as presenting both an opportunity and a threat to their desire to lead a 'normal' life. They describe a wide range of consequences—physical, emotional, social, and vocational—arising from their treatment.

6 Apr 2016

Inflectra (infliximab-dyyb) approved for multiple indications

The U.S. Food and Drug Administration today approved Inflectra (infliximab-dyyb) for multiple indications. Inflectra is administered by intravenous infusion. This is the second biosimilar approved by the FDA.

6 Apr 2016

$Ethnicity, socioeconomic status and place of residence influence risk of experiencing a fracture$

Ethnicity, socioeconomic status and place of residence influence risk of experiencing a fracture

Ethnicity, socioeconomic status and place of residence in the UK all influence the risk of breaking a bone, a new Southampton study has shown.

5 Apr 2016

Rheumatoid arthritis patients who stop smoking reduce their risk of earlier death

University of Manchester-led research has found new evidence to suggest that, not only is smoking associated with earlier deaths in those with rheumatoid arthritis, but also those who stop smoking dramatically reduce their risk of earlier death, as published in Arthritis Care and Research journal.

31 Mar 2016

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Discovery of shared biological properties among DNA variants may help identify new therapeutic targets

TSRI study reveals important traits in LCMV, Lassa virus

Study shows canine AD shares significant features of human version

RA patients more likely to experience hearing loss

Wellderly study finds link between cognitive decline genes and healthy aging

Study indicates that resolvin D1 has anti-arthritic properties

Non-invasive optogenetic therapy can help treat chronic pain

Therapies based on alpha defensins could help treat rheumatoid arthritis

MGH-led study confirms safety of allergy immunotherapy

Study supports screening for HLA-B*5801 gene variant in Asian, black patients with gout

Intestinal bacteria can be used to reduce cancer risk, reveals UCLA study

Taking antibiotics in early childhood can disrupt immune system function lifelong

M10 peptide could help protect systemic sclerosis patients against fibrotic damage

Tips to help treat corns and calluses

Carbohydrate-binding protein controls inflammation in osteoarthritis patients

Researchers develop mouse model for testing vaccines, therapeutics to battle Zika virus

Young arthritis patients have concerns about consequences arising from treatment

Inflectra (infliximab-dyyb) approved for multiple indications

Ethnicity, socioeconomic status and place of residence influence risk of experiencing a fracture

Rheumatoid arthritis patients who stop smoking reduce their risk of earlier death

How innovation in dried blood spot testing is transforming neurological disease monitoring

Unlocking live single-cell functional insights

How microRNA is transforming science: From discovery to diagnostics

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

How innovation in dried blood spot testing is transforming neurological disease monitoring

Unlocking live single-cell functional insights

How microRNA is transforming science: From discovery to diagnostics

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