Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Researchers identify four new genetic regions associated with Behcet's disease

Researchers have identified four new regions on the human genome associated with Behcet's disease, a painful and potentially dangerous condition found predominantly in people with ancestors along the Silk Road.

7 Jan 2013

Biogen Idec files rFIXFc BLA with FDA for treatment of hemophilia B

Today Biogen Idec announced the company recently submitted a Biologics License Application (BLA) to the U.S. Food and Drug Administration (FDA) for the marketing approval of recombinant factor IX Fc fusion protein (rFIXFc) for the treatment of hemophilia B.

7 Jan 2013

EPIRUS’ BOW-015 achieves bioequivalence to Remicade in a single dose comparator trial

EPIRUS Biopharmaceuticals, Inc., formerly known as fourteen22 Inc, announced that its lead asset, BOW-015, achieved bioequivalence to Remicade in a single dose comparator trial.

3 Jan 2013

Crofelemer receives FDA approval for treatment of HIV associated diarrhea

Glenmark Pharmaceuticals Limited announced today that the US Food and Drug Administration has provided Marketing approval to its partner in US, Salix Pharmaceuticals Limited, for Crofelemer 125 mg delayed-release tablets for the symptomatic relief of non-infectious diarrhea in patients with human immunodeficiency virus (HIV)/ acquired immune deficiency syndrome (AIDS) on anti-retroviral therapy (ART).

2 Jan 2013

Small numbers of ANA- and RP-negative patients with systemic sclerosis

There exists a very small subgroup of patients with systemic sclerosis who lack circulating antinuclear antibodies and who do not have Raynaud's phenomenon, research shows.

31 Dec 2012

Weight gain after adolescence has repercussions for hypertension

Individuals who gain weight in adulthood as well as those who are overweight in adolescence and adulthood are at increased risk for hypertension, research suggests.

31 Dec 2012

Early problems in processing knowledge-based information linked to Alzheimer's disease

People who study or treat Alzheimer's disease and its earliest clinical stage, mild cognitive impairment (MCI), have focused attention on the obvious short-term memory problems. But a new study suggests that people on the road to Alzheimer's may actually have problems early on in processing semantic or knowledge-based information, which could have much broader implications for how patients function in their lives.

29 Dec 2012

Developer of Boron Neuron Capture Therapy bestowed National Medal of Science honor

President Barack Obama named University of Missouri researcher M. Frederick Hawthorne as recipient of the National Medal of Science, the highest honor bestowed by the country to scientists. Hawthorne is the director of the International Institute of Nano and Molecular Medicine at the University of Missouri, as well as Curators' Distinguished Professor of Chemistry and Radiology.

29 Dec 2012

Scientists identify molecular mechanism central to development of osteoarthritis pain

Researchers at Rush University Medical Center, in collaboration with researchers at Northwestern University, have identified a molecular mechanism central to the development of osteoarthritis (OA) pain, a finding that could have major implications for future treatment of this often-debilitating condition.

28 Dec 2012

Implementation of appropriateness criteria required for elective procedures

Many of the most common inpatient surgeries in the United States are performed electively. These surgeries are expected to significantly increase with the enactment of the Affordable Care Act.

27 Dec 2012

Cellular metabolism of immune cells protect against viral infections and tumours

New research demonstrates that the cellular metabolism of certain immune cells is closely linked to their function, which includes protecting against viral infections and the development of tumours.

25 Dec 2012

TNF inhibitor efficacy may depend on brain activity

How well a patient responds to tumor necrosis factor inhibitor therapy may depend on brain activity reflecting the individual’s perception of their rheumatoid arthritis, scientists believe.

24 Dec 2012

Viewpoints: Playing chicken on entitlements; 'Getting serious' about mental illness; Hospital labs devastated by Sandy

This is no time for a Grand Bargain, because the Republican Party, as now constituted, is just not an entity with which the president can make a serious deal. If we're going to get a grip on our nation's problems - of which the budget deficit is a minor part - the power of the G.O.P.'s extremists, and their willingness to hold the economy hostage if they don't get their way, needs to be broken. And somehow I don't think that's going to happen in the next few days (Paul Krugman, 12/20).

21 Dec 2012

Biotest receives FDA approval for BIVIGAM to treat primary humoral immunodeficiency

Biotest AG announced today that Biotest Pharmaceuticals Corporation received approval for BIVIGAM for the treatment of patients with Primary Humoral Immunodeficiency (PI) from the U.S. Food and Drug Administration (FDA).

20 Dec 2012

Proteins detected in urine may enable diagnosis of Kawasaki disease

A set of proteins detected in urine by researchers at Boston Children's Hospital may prove to be the first biomarkers for Kawasaki disease, an uncommon but increasingly prevalent disease which causes inflammation of blood vessels that can lead to enlarged coronary arteries and even heart attacks in some children.

20 Dec 2012

Men with fibromyalgia symptoms less likely to receive diagnostic tests

Fibromyalgia is a complex illness to diagnose and to treat. There is not yet a diagnostic test to establish that someone has it, there is no cure and many fibromyalgia symptoms -- pain, fatigue, problems sleeping and memory and mood issues -- can overlap with or get mistaken for other conditions. A new Mayo Clinic study suggests that many people who have fibromyalgia, especially men, are going undiagnosed.

20 Dec 2012

Positive top-line results from Idera’s IMO-3100 Phase 2a trial on plaque psoriasis

Idera Pharmaceuticals today announced that 48% of patients with moderate-to-severe plaque psoriasis (12 of 25) treated with IMO-3100, a selective antagonist of Toll-like Receptors (TLRs) 7 and 9, demonstrated improvements in Psoriasis Area Severity Index (PASI) scores of 35% to 90% from baseline at the completion of a randomized, double-blind, placebo-controlled Phase 2a clinical trial of two dose levels of IMO-3100 administered for four weeks, with a four-week follow-up period.

20 Dec 2012

Enlarged lymph nodes may warn of cancer

Enlarged lymph nodes are a marker for both occult cancer and a long-term risk for malignancy, confirms research published in the British Journal of Haematology.

19 Dec 2012

Amgen expected to enter a guilty plea to unspecified charges

The biotech giant is expected to plead guilty in a New York federal court criminal case. Some reports suggest the charges relate to "misbranding" -- which refers to the promotion of drugs for uses that have not gained the Food and Drug Administration's approval.

19 Dec 2012

Australian scientists receive grants for research on cancer, malaria and rheumatoid arthritis

Scientists at the Walter and Eliza Hall Institute in Melbourne, Australia, have received more than $16 million in Australian Government funding to pursue research into cancer, malaria, rheumatoid arthritis and the immune system, it was announced today.

19 Dec 2012

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Researchers identify four new genetic regions associated with Behcet's disease

Biogen Idec files rFIXFc BLA with FDA for treatment of hemophilia B

EPIRUS’ BOW-015 achieves bioequivalence to Remicade in a single dose comparator trial

Crofelemer receives FDA approval for treatment of HIV associated diarrhea

Small numbers of ANA- and RP-negative patients with systemic sclerosis

Weight gain after adolescence has repercussions for hypertension

Early problems in processing knowledge-based information linked to Alzheimer's disease

Developer of Boron Neuron Capture Therapy bestowed National Medal of Science honor

Scientists identify molecular mechanism central to development of osteoarthritis pain

Implementation of appropriateness criteria required for elective procedures

Cellular metabolism of immune cells protect against viral infections and tumours

TNF inhibitor efficacy may depend on brain activity

Viewpoints: Playing chicken on entitlements; 'Getting serious' about mental illness; Hospital labs devastated by Sandy

Biotest receives FDA approval for BIVIGAM to treat primary humoral immunodeficiency

Proteins detected in urine may enable diagnosis of Kawasaki disease

Men with fibromyalgia symptoms less likely to receive diagnostic tests

Positive top-line results from Idera’s IMO-3100 Phase 2a trial on plaque psoriasis

Enlarged lymph nodes may warn of cancer

Amgen expected to enter a guilty plea to unspecified charges

Australian scientists receive grants for research on cancer, malaria and rheumatoid arthritis

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Reducing polypharmacy through innovative drug formulation technologies

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Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

How innovation in dried blood spot testing is transforming neurological disease monitoring

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