Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

New FDA advisory on Chantix (varenicline)

The U.S. Food and Drug Administration (FDA) has issued a Public Health Advisory to alert health care providers, patients, and caregivers to new safety warnings concerning Chantix (varenicline), a prescription medication used to help patients stop smoking.

5 Feb 2008

Depression and rheumatoid arthritis

Patients with rheumatoid arthritis (RA), the most common chronic inflammatory arthritis, are twice as likely as other individuals to experience depression.

5 Feb 2008

Survey of rheumatic diseases in China

We like to complain about our aches and pains, but rheumatism is not only the preserve of western society.

5 Feb 2008

Protein, macrophage migration inhibitory factor predicts heart attack response and cardiac damage

A protein has been found that influences the response of the heart to a lack of oxygen and blood flow, such as occurs during a heart attack, a team of Yale School of Medicine researchers report in Nature.

4 Feb 2008

Celebrex may disrupt heart rhythm

Celebrex, a popular arthritis drug that blocks pain by inhibiting an enzyme known as COX-2, has been shown in laboratory studies to induce arrhythmia, or irregular beating of the heart, via a novel pathway unrelated to its COX-2 inhibition.

25 Jan 2008

Arthritic knees remain painful after arthroscopic surgery

Trimming damaged tissue through arthroscopic surgery does not relieve pain and swelling in arthritic knees any better than simply flushing loose debris from the joint, according to a new review of evidence.

25 Jan 2008

Stanford study finds transplant patient thrives 2 years after stopping immunosuppressive drugs

Luck smiled on Larry Kowalski when his brother agreed to donate a kidney Kowalski needed to live.

24 Jan 2008

Genmab reaches milestones in Ofatumumab collaboration

The second milestone payment of the collaboration of DKK 87.2 million was triggered by treatment of the first patient in the Phase II study of ofatumumab in Diffuse Large B-Cell Lymphoma (DLBCL), which occurred in 2007.

22 Jan 2008

Genetics behind the disease systemic lupus erythematosus almost completed

A new study has mapped the risk factors behind the autoimmune disease SLE in the entire human genome.

22 Jan 2008

Discovery of multiple genes linked to systemic lupus erythematosus

A landmark genetic study has identified multiple genes linked to systemic lupus erythematosus (SLE), or lupus, a debilitating autoimmune disease that affects an estimated 1.4 million Americans.

21 Jan 2008

Common variations in human DNA signal lupus risk

Scientists have pinpointed a set of common variations in human DNA that signal a higher risk for lupus in women who carry them.

21 Jan 2008

How anti-TNF compounds work

Powerful drugs used to treat patients with rheumatoid arthritis have a profound, previously unrecognized effect on the immune system, breaking up molecular "training camps" for rogue cells that play an increasingly recognized role in autoimmune diseases like rheumatoid arthritis and lupus.

21 Jan 2008

Untreated blood disorder leads to liver cancer and arthritis

Australian researchers have discovered that more than one quarter of men with hemochromatosis develop liver cancer, arthritis and other complications.

20 Jan 2008

Arthritis drug Etanercept clears up symptoms of psoriasis

New research from the United States has found that a drug commonly used to treat arthritis significantly reduces the symptoms of psoriasis in children.

20 Jan 2008

Current state of the art in glycoscience

Sugars were once credited with magical healing powers but are now seen like salt as an evil necessary in small doses but the cause of numerous diseases such as diabetes if taken in excess.

18 Jan 2008

Gold nanoparticles shine brightly in tumors

Solid gold nanoparticles have long been used to treat rheumatoid arthritis and more recently have shown promise in treating various types of cancer.

16 Jan 2008

Bisphosphonates - osteoporosis drugs triple risk of bone necrosis

A University of British Columbia and Vancouver Coastal Health Research Institute study has found that a popular class of osteoporosis drugs nearly triples the risk of developing bone necrosis, a condition that can lead to disfigurement and incapacitating pain.

16 Jan 2008

How asthma and allergy symptoms are triggered

In demonstrating that a group of calcium ion channels play a crucial role in triggering inflammatory responses, researchers at Beth Israel Deaconess Medical Center (BIDMC) have not only solved a longstanding molecular mystery regarding the onset of asthma and allergy symptoms, but have also provided a fundamental discovery regarding the functioning of mast cells.

15 Jan 2008

Researchers find new way to block destructive rush of immune cells

Researchers have found a way to selectively block the ability of white blood cells to "crawl" toward the sites of injury and infection when such mobility drives disease, according to a study published today in The Journal of Experimental Medicine.

15 Jan 2008

Researchers associate six new genetic variants with heart disease risk factor

Using new techniques for rapidly scanning the human genome, researchers have associated levels of cholesterol and triglycerides, two fats in the blood, to 18 genetic variants, six of which represent new DNA regions never before associated with the traits.

15 Jan 2008