Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

YAP and TAZ proteins guide bone development in the womb

A pair of proteins, YAP and TAZ, has been identified as conductors of bone development in the womb and could provide insight into genetic diseases such as osteogenesis imperfecta, known commonly as "brittle bone disease."

4 Jan 2024

IDO2 deficiency in mice leads to behavioral abnormalities resembling autism spectrum disorder

Over the past decades, scientists have made substantial progress unveiling the underlying mechanisms behind many psychiatric disorders.

4 Jan 2024

Yale scientists identify drug target that may alleviate joint degeneration in osteoarthritis

Yale researchers have identified a drug target that may alleviate joint degeneration associated with osteoarthritis, a debilitating condition that afflicts as many as 30 million people in the United States alone, which they report on Jan. 3 in the journal Nature.

3 Jan 2024

Researchers identify microbial enzyme responsible for making urine yellow

Researchers at the University of Maryland and National Institutes of Health have identified the microbial enzyme responsible for giving urine its yellow hue, according to a new study published in the journal Nature Microbiology on January 3, 2024.

3 Jan 2024

Calcium channel blockers reverse muscle weakness in animal model of myotonic dystrophy type 1

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these symptoms in animal models of the disease.

2 Jan 2024

New non-steroidal anti-inflammatory can inhibit the cytokine storm and preserve innate immunity

Very early in the COVID-19 pandemic clinical trials in patients hospitalized with COVID-19 confirmed that corticosteroids like dexamethasone reduced mortality, but they were harmful when applied at the first COVID-19 symptoms, due to the weakening of innate antiviral immunity, leading to delayed viral clearance and adverse outcomes in severe viral pneumonias.

28 Dec 2023

Unraveling nuanced roles of JAK inhibitors in inflammation

Researchers at the Icahn School of Medicine at Mount Sinai have gained a deeper understanding of the nuanced roles of JAK inhibitors, or modulators, in inflammation across various cell types and tissues.

21 Dec 2023

A new test could save arthritis patients time, money, and pain. But will it be used?

Erinn Maury knew Remicade wasn't the right drug for Patti Schulte, a rheumatoid arthritis patient the physician saw at her Millersville, Maryland, practice. Schulte's swollen, painful joints hadn't responded to Enbrel or Humira, two drugs in the same class.

20 Dec 2023

Hip-focused physical therapy provides faster low back pain relief in older adults

When the University of Delaware's Gregory Hicks started his research career two decades ago, he was one of only a few people in the United States studying chronic low back pain in people over 60 years old.

19 Dec 2023

Childhood trauma linked to chronic pain in adulthood

Physical, sexual, or emotional abuse, or neglect, either alone or combined with other types of childhood trauma, increases the risk of chronic pain and related disability in adulthood, according to new research.

19 Dec 2023

Experts call for valuing patient "lived experiences" in diagnostic decisions

Experts today call for more value to be given to patients' 'lived experiences' as a study of over 1,000 patients and clinicians found multiple examples of patient reports being under-valued.

18 Dec 2023

Science’s Breakthrough of the Year: GLP-1 agonists can blunt obesity-associated health problems

Science has named the development of glucagon like peptide-1 (GLP-1) agonists and this year's discovery that these drugs can blunt obesity-associated health problems as its 2023 Breakthrough of The Year.

15 Dec 2023

Researchers identify the culprit responsible for harmful inflammation in certain muscular disorders

Inflammation is an important part of the body's defenses, eliminating threats and repairing damage. When the immune system is overactivated, though, it can turn from friend to foe.

14 Dec 2023

Watch: She had a home and a good-paying job. Then illness and debt upended it all.

Sharon Woodward used to travel the country as a medical technician. She made good money and prided herself on her skills.

11 Dec 2023

EULAR publishes updated recommendations for SLE management

SLE is a heterogeneous disease, which can cause many different manifestations and symptoms, and traditionally did not have many treatment options.

8 Dec 2023

New guidelines offer hope for fatigue management in people with inflammatory RMD

Fatigue is common in people with inflammatory rheumatic and musculoskeletal diseases(RMD). The causes of fatigue are not well understood, and it is likely that they vary between people and over time.

8 Dec 2023

Ashwagandha extracts show promise in reducing stress hormones, study suggests

A systematic review reveals that Withania somnifera (Ashwagandha) extracts can effectively reduce cortisol levels in the short term, offering a natural alternative for stress management, though long-term effects remain unexplored.

6 Dec 2023

Individuals with acne face stigmatizing attitudes from the general public, study finds

A new study highlights how stigmatizing attitudes about individuals with acne may influence social and professional perceptions.

6 Dec 2023

Anti-obesity medications may offer survival benefits for osteoarthritis patients

New research published in Arthritis & Rheumatology suggests that for people overweight or with obesity who also have knee or hip osteoarthritis, a slow-to-moderate-;but not fast-;rate of weight loss caused by anti-obesity medications may lower their risk of premature death.

6 Dec 2023

Exploring the genetic links: Alcohol, smoking, coffee intake, and arthritis risk

The genetic relationship between alcohol consumption, smoking, coffee intake, and the risk of arthritis.

6 Dec 2023

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

YAP and TAZ proteins guide bone development in the womb

IDO2 deficiency in mice leads to behavioral abnormalities resembling autism spectrum disorder

Yale scientists identify drug target that may alleviate joint degeneration in osteoarthritis

Researchers identify microbial enzyme responsible for making urine yellow

Calcium channel blockers reverse muscle weakness in animal model of myotonic dystrophy type 1

New non-steroidal anti-inflammatory can inhibit the cytokine storm and preserve innate immunity

Unraveling nuanced roles of JAK inhibitors in inflammation

A new test could save arthritis patients time, money, and pain. But will it be used?

Hip-focused physical therapy provides faster low back pain relief in older adults

Childhood trauma linked to chronic pain in adulthood

Experts call for valuing patient "lived experiences" in diagnostic decisions

Science’s Breakthrough of the Year: GLP-1 agonists can blunt obesity-associated health problems

Researchers identify the culprit responsible for harmful inflammation in certain muscular disorders

Watch: She had a home and a good-paying job. Then illness and debt upended it all.

EULAR publishes updated recommendations for SLE management

New guidelines offer hope for fatigue management in people with inflammatory RMD

Ashwagandha extracts show promise in reducing stress hormones, study suggests

Individuals with acne face stigmatizing attitudes from the general public, study finds

Anti-obesity medications may offer survival benefits for osteoarthritis patients

Exploring the genetic links: Alcohol, smoking, coffee intake, and arthritis risk

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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