Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

EULAR launches ENTRI initiative to boost rheumatic disease research across Europe

The European Alliance of Associations for Rheumatology (EULAR) is proud to announce the launch of the EULAR Network of TRIal Centres (ENTRI) initiative.

14 Jun 2024

Blood interferon signature reveals key differences in pediatric-onset Sjögren's disease

Due to differences in clinical presentation and limited knowledge, diagnosing Sjögren's disease in children can be challenging.

14 Jun 2024

New insights into predictors of organ damage in childhood-onset SLE

Childhood-onset systemic lupus erythematosus (cSLE) is a chronic, severe autoimmune disorder that carries a risk of early organ damage.

14 Jun 2024

Tackling challenges in childhood arthritis transition to adult care

Rheumatological diseases can affect people during childhood, the most common being juvenile idiopathic arthritis (JIA).

14 Jun 2024

Exploring the comorbidities associated with osteoarthritis

Osteoarthritis is the most common arthritis worldwide, and has an increasing global burden of disability and healthcare utilization.

14 Jun 2024

Mutated TREX1 gene linked to catastrophic DNA damage and deadly rare disease

TREX1 is a gene that is supposed to direct the maintenance of the entire body's DNA, but new research shows that when people are born with mutated TREX1, it causes catastrophic damage to the DNA over time, resulting in a deadly rare disease called retinal vasculopathy with cerebral leukoencephalopathy (RVCL).

13 Jun 2024

New insights into physical activity adoption for rheumatic patients

An HPR abstract sessions at the 2024 EULAR congress looked specifically at harnessing the benefits of exercise in rheumatic and musculoskeletal diseases (RMD) – and the challenges to their practical implementation.

13 Jun 2024

Dose reduction of glucocorticoids in systemic lupus erythematosus

Glucocorticoids are a mainstay of treatment for systemic lupus erythematosus (SLE). But due to long-term adverse effects, dose reduction is becoming a crucial part of treat-to-target management goals.

13 Jun 2024

New insights into blood precursors of pathogenic macrophages in RA

The exact origin and precursor differentiation route of tissue macrophages remains controversial. At the 2024 congress of EULAR - The European Alliance of Associations for Rheumatology - new work sheds light on blood precursors of pathogenic tissue macrophages.

13 Jun 2024

Study demonstrates efficacy of treat-to-target in early axial spondyloarthritis

Early therapeutic interventions in inflammatory rheumatic diseases have proven successful in inducing drug-free remission, and EULAR - The European Alliance of Associations for Rheumatology - recommends early intervention in arthritis, since conventional synthetic disease-modifying antirheumatic drugs (csDMARD) have been shown to slow disease progression in both rheumatoid and psoriatic arthritis.

13 Jun 2024

New research sheds light on IL-23's role in chronic inflammatory bowel diseases

Scientists at Weill Cornell Medicine discovered a previously unknown link between two key pathways that regulate the immune system in mammals-;a finding that impacts our understanding of chronic inflammatory bowel diseases (IBD).

12 Jun 2024

Multi-center study validates systemic score in identifying high-risk patients with Still's disease

A multi-centre, observational, prospective study was designed to evaluate the clinical usefulness of the systemic score in predicting life-threatening evolution – defined as the development of macrophage activation syndrome (MAS) and/or mortality.

12 Jun 2024

Study reveals unconscious fear of exercise in knee osteoarthritis patients

Knee osteoarthritis (OA) is a common cause of pain and joint stiffness. And while physical activity is known to ease symptoms, only one in 10 people regularly exercise.

11 Jun 2024

EULAR develops new classification criteria for hand osteoarthritis

At present, classifying hand osteoarthritis (OA) is based on clinical findings, and available tools are not able to distinguish between certain phenotypes.

7 Jun 2024

STew: A new method for unveiling the spatial fingerprint of diseases

In disease research, it's important to know gene expression and where in a tissue the expression is happening, but marrying the two sets of information can be challenging.

4 Jun 2024

Researchers show the interplay of socioeconomic status and genetics on disease risk

Differences in socioeconomic status (SES) are known to be linked to differences in the risk of developing disease.

3 Jun 2024

Experimental treatment for metastatic pancreatic cancer shows promise in phase 2 clinical trial

Clinicians at Georgetown University's Lombardi Comprehensive Cancer Center reported promising preliminary findings based on outcomes in the first six patients with metastatic pancreatic cancer enrolled in a phase 2 clinical trial of the experimental drug BXCL701 in combination with the immunotherapy drug pembrolizumab (Keytruda).

3 Jun 2024

Synthetic cartilage plugs may help heal osteochondral defects and avoid total knee replacements

Osteochondral defects (OCDs) can cause damage to cartilage and underlying bone, leading to chronic pain and loss of joint function.

31 May 2024

Wake Forest researchers to study bone health post-bariatric surgery with $1.5 million NIH grant

Researchers at Wake Forest University of School of Medicine have received a five-year, $1.5 million grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the National Institutes of Health, to study bone microarchitecture in patients following bariatric surgery.

30 May 2024

Targeting Ctdnep1: A potential therapeutic approach to combat bone loss

Osteoporosis, a condition characterized by porous and fragile bones, poses a significant threat to skeletal health.

30 May 2024

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

EULAR launches ENTRI initiative to boost rheumatic disease research across Europe

Blood interferon signature reveals key differences in pediatric-onset Sjögren's disease

New insights into predictors of organ damage in childhood-onset SLE

Tackling challenges in childhood arthritis transition to adult care

Exploring the comorbidities associated with osteoarthritis

Mutated TREX1 gene linked to catastrophic DNA damage and deadly rare disease

New insights into physical activity adoption for rheumatic patients

Dose reduction of glucocorticoids in systemic lupus erythematosus

New insights into blood precursors of pathogenic macrophages in RA

Study demonstrates efficacy of treat-to-target in early axial spondyloarthritis

New research sheds light on IL-23's role in chronic inflammatory bowel diseases

Multi-center study validates systemic score in identifying high-risk patients with Still's disease

Study reveals unconscious fear of exercise in knee osteoarthritis patients

EULAR develops new classification criteria for hand osteoarthritis

STew: A new method for unveiling the spatial fingerprint of diseases

Researchers show the interplay of socioeconomic status and genetics on disease risk

Experimental treatment for metastatic pancreatic cancer shows promise in phase 2 clinical trial

Synthetic cartilage plugs may help heal osteochondral defects and avoid total knee replacements

Wake Forest researchers to study bone health post-bariatric surgery with $1.5 million NIH grant

Targeting Ctdnep1: A potential therapeutic approach to combat bone loss

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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