Bipolar Disorder

Bipolar disorder, also known as manic-depressive illness, is a brain disorder that causes unusual shifts in mood, energy, activity levels, and the ability to carry out day-to-day tasks. Symptoms of bipolar disorder are severe.

The Genetics of Mental Disorder

No psychiatric or mental disorder has a fully genetic basis or heritability, and many environmental factors may influence the likelihood of a particular disorder.

Bipolar Disorder Diagnosis

Bipolar Disorder Interventions

What is Schizoaffective Disorder?

Bipolar Disorder and Parkinson’s

Bipolar Disorder Treatment

Bipolar Disorder

Intermittent Explosive Disorder Causes

Generalized Anxiety Disorder Comorbidities

Bipolar Disorder Counseling

What is Olanzapine?

Bipolar Disorder Symptoms

Latest Bipolar Disorder News and Research

USC researchers map genetic architecture of the human corpus callosum

For the first time, a research team led by the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC has mapped the genetic architecture of a crucial part of the human brain known as the corpus callosum-the thick band of nerve fibers that connects the brain's left and right hemispheres.

4 Nov 2025

International experts urge the reclassification of postpartum psychosis to improve treatment

An international panel of leading women's mental health experts – including UVA Health's Jennifer Payne, MD – is calling to reclassify postpartum psychosis as its own category of mental illness to improve the care new mothers receive.

3 Nov 2025

New $4.4 million grant funds first study of prefrontal cortical stimulation in severe bipolar disorder

A University of Minnesota Medical School research team, led by Ziad Nahas, MD, has been awarded a $4.4 million grant for a first-in-the-world study of prefrontal cortical stimulation in severe bipolar disorder.

31 Oct 2025

Low-cost biosensor identifies altered protein levels associated with psychiatric disorders

Brazilian researchers have developed a low-cost, portable biosensor that can quickly identify a protein whose altered levels are associated with psychiatric disorders, such as depression, schizophrenia, and bipolar disorder.

30 Oct 2025

Mount Sinai receives $4.5 million grant to investigate neural mechanisms underlying bipolar disorder

The Icahn School of Medicine at Mount Sinai is pleased to announce it has received a three-year, $4.5 million grant from BD2: Breakthrough Discoveries for thriving with Bipolar Disorder to investigate the neural mechanisms underlying bipolar disorder and pioneer novel neuromodulation-based treatment strategies.

28 Oct 2025

BD² expands global effort to examine the key mechanisms of bipolar disorder

Today, BD², or Breakthrough Discoveries for thriving with Bipolar Disorder, announced its third round of Discovery Research grants, totaling nearly $18 million – expanding a comprehensive global effort to examine the key mechanisms of bipolar disorder.

28 Oct 2025

Scientists uncover excessive maturation and aging in the hippocampus

In a groundbreaking study, researchers at Fujita Health University and the Tokyo Metropolitan Institute of Medical Science have uncovered a previously overlooked form of brain abnormality linked to anxiety: excessive maturation and aging in the hippocampus, a state they term "hyper-maturity."

27 Oct 2025

Ribosomal RNA found to share unique motifs with nervous system genes

Ribosomal RNA (rRNA) is a type of molecule and a key building block of the ribosome, the cell's protein-making machinery. rRNA accounts for much of the RNA in a cell, and it's crucial for life.

14 Oct 2025

Voter health trends reveal strong backing for Reform UK

Poorer health is linked to a higher proportion of votes for the populist right wing political party, Reform UK, indicates an analysis of the 2024 general election voting patterns in England, published online in the open access journal BMJ Open Respiratory Research.

14 Oct 2025

New insights can reshape psychiatric practice across continents

In a compelling Genomic Press Interview published today in Genomic Psychiatry, Dr. Bruce M. Cohen discusses results and insights that are reshaping international approaches to understanding and treating neuropsychiatric disorders.

14 Oct 2025

Genetic study reveals links between cannabis use and mental health

University of California San Diego of Medicine researchers, in collaboration with the genetic testing company 23andMe, have identified regions of the human genome associated with cannabis use, uncovering new relationships with psychiatric, cognitive and physical health.

13 Oct 2025

Dermatological symptoms could signal higher risk in psychiatric patients

Scientists have discovered that mental health patients who have skin conditions may be more at risk of worse outcomes, including suicidality and depression.

13 Oct 2025

Study links skin conditions to worse outcomes in mental health patients

Scientists have discovered that mental health patients who have skin conditions may be more at risk of worse outcomes, including suicidality and depression.

9 Oct 2025

Nasal spray of gold nanoparticles delivers lithium directly to the brain

In the form of a 'nasal spray', tiny gold particles act as carriers, delivering a treatment directly to the brain: developed by scientists at the Università Cattolica Rome campus/Fondazione Policlinico Universitario A. Gemelli IRCCS, a new nanotechnological device for the treatment and prevention of neuropsychiatric and neurodegenerative diseases.

8 Oct 2025

Harnessing AI tools for better treatment of serious mental illnesses

Serious mental illnesses (SMI) take a tremendous toll on individuals, their friends and family, and society as a whole.

6 Oct 2025

$3.7 million grant supports research on perimenopause and its potential impacts on mental health

For decades, women's midlife experiences have been largely overlooked by medical research. Despite previous assumptions about midlife mental health risks, relatively little research has systematically investigated the connections between hormonal fluctuations and psychological symptoms.

6 Oct 2025

Red meat in healthy diet linked to better brain nutrients and gut diversity

A study of 3,600+ participants reveals red meat in high-HEI diets enhances brain-supporting nutrients without disrupting gut health or mental well-being.

2 Oct 2025

New study reveals molecular basis of Long COVID brain fog

Even though many years have passed since the start of the COVID-19 pandemic, the effects of infection with SARS-CoV-2 are not completely understood.

30 Sep 2025

Lab-grown mini brains reveal neural misfires linked to schizophrenia and bipolar disorder

Pea-sized brains grown in a lab have for the first time revealed the unique way neurons might misfire due to schizophrenia and bipolar disorder, psychiatric ailments that affect millions of people worldwide but are difficult to diagnose because of the lack of understanding of their molecular basis.

22 Sep 2025