Bipolar Disorder

Bipolar disorder, also known as manic-depressive illness, is a brain disorder that causes unusual shifts in mood, energy, activity levels, and the ability to carry out day-to-day tasks. Symptoms of bipolar disorder are severe.

The Genetics of Mental Disorder

No psychiatric or mental disorder has a fully genetic basis or heritability, and many environmental factors may influence the likelihood of a particular disorder.

Intermittent Explosive Disorder Causes

Bipolar Disorder Treatment

Bipolar Disorder

What is Schizoaffective Disorder?

Bipolar Disorder and Parkinson’s

Bipolar Disorder Counseling

What is Olanzapine?

Bipolar Disorder Interventions

Bipolar Disorder Diagnosis

Generalized Anxiety Disorder Comorbidities

Bipolar Disorder Symptoms

Latest Bipolar Disorder News and Research

Study finds sex differences in schizophrenia and bipolar disorder

Schizophrenia and bipolar disorder are serious mental illnesses that affect both males and females, but research in Acta Psychiatrica Scandinavica indicates that sex may influence the characteristics and course of these conditions.

3 Sep 2025

Researchers reveal how diseases interact at the genetic level

2 Sep 2025

Cardiovascular outcomes worsen in patients with mental health conditions

Every 34 seconds, someone in the United States dies from heart disease. As nearly half of the country suffers from some form of cardiovascular disease (CVD), another 1 in 4 adults experience a mental health disorder in their lifetime, signaling an inevitable overlap.

28 Aug 2025

Gut bacteria and insomnia influence each other in small but significant ways, study shows

Scientists used Mendelian randomisation to explore the two-way relationship between gut microbiota and insomnia, analyzing GWAS data from over 386,000 individuals and two major microbiome cohorts. The study found only limited taxa surviving strict correction, suggesting small but causal links that highlight the gut–brain axis in sleep health.

21 Aug 2025

Young adults with bipolar disorder show signs of early heart dysfunction

Cardiovascular disease is the leading cause of premature deaths in patients with bipolar disorder worldwide.

19 Aug 2025

Patients recall inadequate disclosure of electroconvulsive therapy risks

The medical pros of electroconvulsive therapy (ECT) are being exaggerated while the risks are being downplayed, suggest the findings of a survey on the type of information patients and their relatives/friends recall having been given before the procedure, and published online in the Journal of Medical Ethics.

17 Aug 2025

Scientists reveal how rare gene mutations drive schizophrenia risk

Researchers analyzed the largest exome-sequencing dataset to date and identified new rare coding variants and genes linked to schizophrenia risk. The study highlights converging genetic pathways, implicating chromatin organization and GABAergic signaling in schizophrenia neurobiology.

4 Aug 2025

Uncovering origins of autism, depression, Parkinson's in fetal brain

The origin of some neuropsychiatric diseases, such as autism, bipolar disorder, or depression, and certain neurodegenerative diseases, Alzheimer's and Parkinson's, can be found in very early stages of brain formation in the fetus. That is, earlier than previously recognized, according to a study by the Hospital del Mar Research Institute and Yale University, published in Nature Communications.

26 Jul 2025

Automated cage monitoring system reveals behavioral changes in schizophrenia mouse model

Schizophrenia is a serious mental health condition that affects thoughts, moods, perceptions, and behaviors.

24 Jul 2025

Study validates stem cell models for neurological diseases

In a comprehensive Genomic Press perspective (peer-reviewed review) article, an international team of neuroscientists has outlined crucial validity standards that could transform how researchers use stem cell technology to study devastating brain disorders.

15 Jul 2025

Maltreatment in early childhood tied to lasting behavioral challenges

Childhood maltreatment leaves deep and lasting marks that have far-reaching consequences, extending beyond immediate trauma and affecting survivors in ways that are often invisible and misunderstood.

11 Jul 2025

Transforming OCD treatment through research and innovation

Obsessive-compulsive disorder (OCD) impacts approximately 2% of the global population, often preventing individuals from living life to their full potential.

2 Jul 2025

Many ADHD trials in adults lack proper diagnostic standards

Millions of adults around the world are diagnosed with ADHD every year, and there is a great need for research in the field.

1 Jul 2025

New study reveals how diverse brain cells unite to guide decisions

Every decision begins invisibly. Long before someone acts, the brain is already hard at work gathering evidence, weighing options, and gradually committing to a choice.

27 Jun 2025

TET1 identified as key regulator in cancer and chronic disease

Recent findings shed new light on the critical role of TET1, a pivotal player in epigenetic regulation, in the development and progression of various clinical diseases.

25 Jun 2025

Study finds nearly double risk of depression and anxiety in autoimmune patients

Living with an autoimmune disease is linked to a near doubling in the risk of persistent mental health issues, such as depression, generalised anxiety, and bipolar disorder, with these risks higher in women than in men, finds a large population-based UK study, published in the open access journal BMJ Mental Health.

25 Jun 2025

Genetic markers show promise in predicting mood disorder treatment outcomes

In a comprehensive Genomic Press Thought Leaders Invited Review, researchers have synthesized findings from dozens of studies examining how genetic markers for mood disorders influence treatment outcomes and clinical features across major psychiatric conditions.

24 Jun 2025

Rising temperatures linked to more severe sleep apnea worldwide

Sleep apnea will become more common and more severe due to global warming, leading to increased health and economic burdens across the globe, warn Flinders University sleep experts.

16 Jun 2025

Bitter 'supertaster gene' tied to bipolar disorder and poor kidney function

People who carry a bitter 'supertaster gene' have been linked to various health conditions including bipolar disorder and poor kidney function, University of Queensland researchers have found.

12 Jun 2025

Physical comorbidities from mental illness drive up hospital strain in Europe

A recent study led by Judit Simon from the Department of Health Economics, Center for Public Health, at the Medical University of Vienna shows for the first time comprehensively the extent to which people with mental disorders suffer from physical illnesses - and the resulting hospital costs.

11 Jun 2025