Cancer News and Research

Latest Cancer News and Research

Innovative treatment may help prevent brain swelling, death in stroke patients

New research has provided more evidence that an innovative treatment strategy may help prevent brain swelling and death in stroke patients. J. Marc Simard, professor of neurosurgery at the University of Maryland School of Medicine, along with colleagues at Yale University and Massachusetts General Hospital, found that Cirara, an investigational drug, powerfully reduced brain swelling and death in patients who had suffered a type of large stroke called malignant infarction, which normally carries a high mortality rate.

19 Mar 2016

Novel plasmid-based microRNA inhibitor system effectively prevents microRNA activity in cells

Today at the 45th Annual Meeting & Exhibition of the American Association for Dental Research, researcher Brad Amendt, University of Iowa, Iowa City, USA, will present a study titled "New Biotechnology to Inhibit MicroRNA Activity and Novel Applications for Craniofacial and Dental Research."

19 Mar 2016

Manipulation of NAD could lead to potential therapy for acute kidney injury

Approximately one out of five hospitalized adults and one out of three hospitalized children worldwide experience acute kidney injury, the sudden loss of kidney function. Many different factors, including surgery, chemotherapy or shock, can lead to acute kidney injury, but exactly why the kidneys are so vulnerable to these and other stressors has not been well understood.

19 Mar 2016

Neutralizing acidic tumor environment increases efficacy of immune-targeting cancer therapies

Cancer cells have the ability to grow in an acidic tumor environment that is detrimental to other cells, including immune cells. In a Cancer Research cover article published this week, Moffitt Cancer Center reported that neutralizing the acidic tumor environment increases the efficacy of several immune-targeting cancer therapies.

19 Mar 2016

Value of PD-L1 testing in NSCLC debated

Two viewpoint articles published in JAMA Oncology provide opposing opinions on the benefit of testing for programmed death-ligand 1 expression in patients with non-small-cell lung cancer treated with checkpoint inhibitors.

18 Mar 2016

Newly developed computer models can simulate stem cell transplant recovery

Scientists at Virginia Commonwealth University have developed computer models that can simulate the recovery of the immune system in patients undergoing stem cell transplants.

18 Mar 2016

UT Southwestern researchers identify new role for protein linked to neurological disorders and cancers

Researchers at UT Southwestern Medical Center have identified a second role for a class of RNA-binding proteins, revealing new insights about neurological diseases and conditions associated with this protein such as autism, epilepsy, and certain types of cancer.

18 Mar 2016

Training foreign medical graduates in surgical oncology may help alleviate local burden of cancer

Many low- and middle-income countries do not have a defined medical specialty in surgical oncology and lack an educational infrastructure to respond to the local burden of cancer, but a Memorial Sloan Kettering Cancer Center fellowship is succeeding in addressing this problem by training foreign medical graduates (FMG) in surgical oncology.

18 Mar 2016

UC San Diego researchers use CRISPR-Cas9 system to target RNA in living cells for first time ever

The genetic code stored in DNA determines everything from the color of our eyes to our susceptibility to disease. This has motivated scientists to sequence the human genome and develop ways to alter the genetic code, but many diseases are linked to a different fundamental molecule: RNA.

18 Mar 2016

Genomic profiling could help provide targeted therapies for difficult to treat cancer tumors

Research from Rutgers Cancer Institute of New Jersey examining difficult to treat cancer tumors through genomic profiling shows that tumors with alterations in a signaling pathway responsible for cell regulation may respond to targeted therapy regardless of where the tumor originated in the body.

18 Mar 2016

Clinical study finds no added benefit of using four TB drugs to save people with advanced HIV/AIDS

In a report on the so-called REMEMBER (Reducing Early Mortality and Early Morbidity by Empiric Tuberculosis Treatment) study -- a 10-nation, randomized clinical trial of adult outpatients -- investigators concluded that there was no added benefit of using four drugs for TB over just using one drug, isoniazid, to save lives in people with advanced HIV/AIDS.

18 Mar 2016

Study sheds light on role of RNA editing in cancer

A new study provides insight on the potential role played by RNA (ribonucleic acid) editing in cancer. The findings, which appear online in the journal Scientific Reports, may further our understanding of an emerging mechanism implicated in tumor initiation and progression, and may thus lead to the development of better treatment options in the future.

18 Mar 2016

UW-Madison neuroscientist discover genetic machinery that causes maturation in young nerve cells

In one of the first studies to 'read' the genetic activity inside individual brain cells, University of Wisconsin-Madison neuroscientist Xinyu Zhao has identified the genetic machinery that causes maturation in a young nerve cell. The cells under study came from the hippocampus, a memory-related structure that is the only place in a mammal's brain where new neurons can form throughout life.

18 Mar 2016

Neo-Bioscore staging system adds HER2 status for precise prognostic stratification of breast cancer subtypes

A new breast cancer staging system developed by researchers at The University of Texas MD Anderson Cancer Center finds that incorporating tumor biology is a critical prognostic indicator for women who undergo neoadjuvant, or pre-surgical, therapy for breast cancer.

18 Mar 2016

Inhibiting cholesterol esterification can potentiate antitumor activity of killer T cells

As key players in the immune system, T cells provide tumor surveillance and have direct antitumor effects. However, tumors can escape T-cell attack through various mechanisms in the tumor microenvironment. Reactivating the antitumor effects of T cells has shown great clinical benefits in treating various cancers.

18 Mar 2016

Cancer News and Research

Latest Cancer News and Research

Innovative treatment may help prevent brain swelling, death in stroke patients

Novel plasmid-based microRNA inhibitor system effectively prevents microRNA activity in cells

Manipulation of NAD could lead to potential therapy for acute kidney injury

Neutralizing acidic tumor environment increases efficacy of immune-targeting cancer therapies

Value of PD-L1 testing in NSCLC debated

Newly developed computer models can simulate stem cell transplant recovery

UT Southwestern researchers identify new role for protein linked to neurological disorders and cancers

Training foreign medical graduates in surgical oncology may help alleviate local burden of cancer

UC San Diego researchers use CRISPR-Cas9 system to target RNA in living cells for first time ever

Genomic profiling could help provide targeted therapies for difficult to treat cancer tumors

Clinical study finds no added benefit of using four TB drugs to save people with advanced HIV/AIDS

Study sheds light on role of RNA editing in cancer

UW-Madison neuroscientist discover genetic machinery that causes maturation in young nerve cells

Neo-Bioscore staging system adds HER2 status for precise prognostic stratification of breast cancer subtypes

Inhibiting cholesterol esterification can potentiate antitumor activity of killer T cells

Secondary non-Hodgkin's lymphoma a concern for CML patients using TKIs

Vascular events in CML may not be linked to TKI therapy

New subtype of bladder cancer shares molecular signatures with breast cancer

Molecular basis for tongue cancer progression: an interview with Dr Simona Principe

New study reveals why certain cancer drugs not always effective in halting tumor growth

Cancer Research - Second Edition eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

Cancer News and Research

Latest Cancer News and Research

Cancer Research - Second Edition eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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