Cancer News and Research

Latest Cancer News and Research

GenomeDx announces publication of positive validation study for Decipher Prostate Cancer Classifier

GenomeDx Biosciences today announced the publication of a positive validation study for the Decipher® Prostate Cancer Classifier, a genomic test for prostate cancer. The study, published in the Journal of Clinical Oncology, showed that patients with low genomic risk (as determined by Decipher) may be optimally managed with observation after radical prostatectomy (prostate surgery), while those with high genomic risk (as determined by Decipher) may be better managed earlier with adjuvant radiotherapy.

10 Feb 2015

HPV vaccination does not affect sexual behaviours

Research has shown that human papillomavirus (HPV) vaccination is not associated with increases in sexually transmitted infections (STIs).

10 Feb 2015

University of Tokyo researchers reveal how TLR9 binds to pathogen DNA

University of Tokyo researchers have elucidated how Toll-like receptor 9 (TLR9) binds to pathogen DNA, activating the innate immune system. This discovery is vital for the design of new antiviral, antibacterial, allergy and other drugs targeting TLR9.

10 Feb 2015

HPV vaccine does not increase rates of STIs in adolescent females

Receiving the human papillomavirus vaccine does not increase rates of sexually transmitted infections (STIs) in adolescent females. The vaccine, which can prevent cervical cancer in women, has had a low uptake, partly because of concerns about how it will affect adolescent sexual activity.

10 Feb 2015

Researchers identify axitinib as promising candidate to treat drug-resistant leukaemia

A study led by researchers at the Institute for Molecular Medicine Finland FIMM and Faculty of Medicine, University of Helsinki and the Helsinki University Central Hospital Comprehensive Cancer Center, in close collaboration with researchers at Pfizer, has identified a previously unrecognized action of Pfizer's axitinib as a potent inhibitor of the dominant mutation that confers drug resistance to all well tolerated treatments in patients with certain types of leukemia.

10 Feb 2015

Study describes novel screening system that has potential to uncover effective ovarian cancer drugs

University of Chicago Medicine researchers have built a model system that uses multiple cell types from patients to rapidly test compounds that could block the early steps in ovarian cancer metastasis. Their three-dimensional cell-culture system, adapted for high-throughput screening, has enabled them to identify small molecules that can inhibit adhesion and invasion, preventing ovarian cancers from spreading to nearby tissues.

10 Feb 2015

Drug similar to Gleevec may help tame some brain cancers

The drug Gleevec (imatinib mesylate) is well known not only for its effectiveness against chronic myeloid leukemia (CML) and acute lymphoblastic leukemia, but also for the story behinds its development. The drug was specifically designed to target an abnormal molecule--a fusion of two normal cell proteins--that fueled a tumor's growth.

10 Feb 2015

Quest Diagnostics, Myriad Genetics reach agreement to end BRCA gene-patent litigation

Quest Diagnostics, the world's leading provider of diagnostic information services, today announced that it and Myriad Genetics Inc. have reached an agreement that ends their BRCA gene-patent litigation.

From Quest Diagnostics 10 Feb 2015

Roche announces acquisition of Signature Diagnostics

Roche announced today the acquisition of Signature Diagnostics AG, a privately held company based in Potsdam, Germany. Signature is a translational oncology and genomics company that develops large blood plasma and tissue biobanks in multiple cancers, including colorectal and lung, which are constructed from multicenter prospective clinical studies.

From Roche Sequencing and Life Science 10 Feb 2015

Scientists find that collagen 'cross-links' can determine tumor's ability to grow and spread

When skyscrapers go up, contractors rely on an infrastructure of steel beams and braces. Some cancers grow the same way, using a biological matrix from which the tumor can thrive and spread.

10 Feb 2015

New model proposed for predicting outcomes more accurately in HPV-related throat cancer patients

Researchers at the Princess Margaret Cancer Centre are proposing a new model to enable doctors to predict outcomes more accurately for patients with throat cancers specifically caused by Human Papillomavirus (HPV).

10 Feb 2015

Griffith research unlocks more about cancer

A research collaboration between Griffith and the Malaghan Institute in Wellington, New Zealand has made the discovery that mitochondria are capable of passing through the healthy membrane of a host cell into defective tumour cells, possibly kicking off the rapid proliferation of tumour cells which is the hallmark of cancer.

10 Feb 2015

Radiation therapy more effective at preventing recurrence of ductal carcinoma in situ

In a surprising finding, a collaborative national clinical trials group (RTOG) including Dartmouth-Hitchcock's Alan Hartford, MD, PhD, discovered that radiation therapy in addition to chemotherapy was even more effective at preventing recurrence of ductal carcinoma in situ (DCIS) than previously thought.

10 Feb 2015

Drugs designed to target NHE9 protein could help fight glioblastoma

Applying lessons learned from autism to brain cancer, researchers at The Johns Hopkins University have discovered why elevated levels of the protein NHE9 add to the lethality of the most common and aggressive form of brain cancer, glioblastoma. Their discovery suggests that drugs designed to target NHE9 could help to successfully fight the deadly disease.

10 Feb 2015

Discovery leads to new understanding of cancer metastasis

In a breakthrough in the understanding of how cancer spreads, researchers at the University of Virginia School of Medicine have identified a substance secreted by lung cancer cells that enables them to metastasize, beginning their deadly march to other sites in the body.

10 Feb 2015

Researchers discover inherited genetic variations associated with treatment-related hearing loss

St. Jude Children's Research Hospital investigators have discovered inherited genetic variations that are associated with rapid hearing loss in young cancer patients treated with the drug cisplatin. The research appears in the current online issue of the scientific journal Nature Genetics.

10 Feb 2015

Study links previously unknown genetic anomalies to breast cancer in African American family members

The "Jewels in our Genes" study, led by University at Buffalo researcher Heather Ochs-Balcom, has uncovered previously unknown segments of DNA shared by African American family members who have breast cancer. "The discovery of these regions supports our hypothesis that there are still undiscovered breast cancer genes that may be unique to African Americans," says Ochs-Balcom, PhD, a genetic epidemiologist in the UB Department of Epidemiology and Environmental Health.

10 Feb 2015

People living beside the sea have higher vitamin D levels

People living close to the coast in England have higher vitamin D levels than inland dwellers, according to a new study published in the journal Environment International.

10 Feb 2015

Cancer researchers find important clues to why tumor cells become 'good' or 'bad'

For the first time, Keck Medicine of the University of Southern California cancer researchers have traced the origins of colorectal cancer cells, finding important clues to why tumor cells become "good" or "bad," with the potential of stopping them before they start.

10 Feb 2015

Scientists potentially discover new therapeutic targets to halt progression of tumor cells

Chronic inflammation is directly associated with several types of cancer, yet the reasons as to why this happens at a cellular level remain unclear. Now, an international team of scientists led by researchers at The Wistar Institute has identified a multistep process showing not only how these cancers develop but also potentially discovering new therapeutic targets that could halt the formation and progression of tumor cells.

10 Feb 2015

Cancer News and Research

Latest Cancer News and Research

GenomeDx announces publication of positive validation study for Decipher Prostate Cancer Classifier

HPV vaccination does not affect sexual behaviours

University of Tokyo researchers reveal how TLR9 binds to pathogen DNA

HPV vaccine does not increase rates of STIs in adolescent females

Researchers identify axitinib as promising candidate to treat drug-resistant leukaemia

Study describes novel screening system that has potential to uncover effective ovarian cancer drugs

Drug similar to Gleevec may help tame some brain cancers

Quest Diagnostics, Myriad Genetics reach agreement to end BRCA gene-patent litigation

Roche announces acquisition of Signature Diagnostics

Scientists find that collagen 'cross-links' can determine tumor's ability to grow and spread

New model proposed for predicting outcomes more accurately in HPV-related throat cancer patients

Griffith research unlocks more about cancer

Radiation therapy more effective at preventing recurrence of ductal carcinoma in situ

Drugs designed to target NHE9 protein could help fight glioblastoma

Discovery leads to new understanding of cancer metastasis

Researchers discover inherited genetic variations associated with treatment-related hearing loss

Study links previously unknown genetic anomalies to breast cancer in African American family members

People living beside the sea have higher vitamin D levels

Cancer researchers find important clues to why tumor cells become 'good' or 'bad'

Scientists potentially discover new therapeutic targets to halt progression of tumor cells

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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Cancer News and Research

Latest Cancer News and Research

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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