Cancer News and Research

Latest Cancer News and Research

Avila's PI3Kα inhibitor preclinical study data presented at AACR meeting

Avila Therapeutics, Inc., a biotechnology company developing novel targeted covalent drugs, today presented results of preclinical studies on its novel Phosphoinositide 3-kinase alpha inhibitor at the American Association for Cancer Research 102nd Annual Meeting in Orlando, Florida.

6 Apr 2011

Henry Ford performs partial nephrectomy with new, robotically controlled ultrasound probe

Henry Ford Hospital was the first hospital world-wide to use a new, robotically controlled ultrasound probe to help remove a cancerous tumor from a kidney.

6 Apr 2011

Expression of key tumor suppressor protein induces premature aging

Cancer risk increases with age, and scientists have long perceived a possible evolutionary tradeoff between longer lifespan and greater risk of cancer. Now, researchers at Fox Chase Cancer Center find direct evidence for that tradeoff in new data showing that expression of a key tumor suppressor protein induces premature aging in mice.

6 Apr 2011

Higher prescribed doses associated with increased risk of opioid overdose death

In an analysis of opioid prescription patterns and deaths, receiving higher prescribed doses is associated with an increased risk of opioid overdose death, but receiving both as-needed and regularly scheduled doses is not associated with overdose risk, according to a study in the April 6 issue of JAMA.

6 Apr 2011

NuGEN, Roche develop unique genomic sample preparation solutions

454 Life Sciences, a Roche Company, and NuGEN Technologies, announced today the development of a unique sample preparation method and high-throughput sequencing solution for small and degraded RNA samples.

6 Apr 2011

Extreme weight gain in breast cancer survivors associated with poorer outcomes

Breast cancer survivors who experience extreme weight gain have an increased risk of death after breast cancer diagnosis. Moderate weight gain did not affect breast cancer outcomes.

6 Apr 2011

New insight into embryonic tissue separation

As our bodies form, cells within the embryo divide and separate. Certain cells come together to form the outer layer, or ectoderm, of the early embryo, and give rise to tissue such as the skin and nervous system.

6 Apr 2011

Pervasis' PVS-30200 study data in prostate cancer presented at AACR meeting

Pervasis Therapeutics, Inc. today announced preclinical data showing positive effects of PVS-30200, the company's investigational cell therapy for the treatment of solid tumors, on controlling tumor growth and inhibiting metastases in an animal model of prostate cancer.

6 Apr 2011

Scientists develop new method to identify factors that suppress cancer gene expression

Tumor suppressor genes normally control the growth of cells, but cancer can spring up when these genes are silenced by certain chemical reactions that modify chromosomes.

6 Apr 2011

Lack or loss of SIRT3 protein induces proliferation of breast cancer cells

Research published in the Cancer Cell journal in March was a significant step in knowing the causes of cancer better, especially breast cancer, revealing that the lack or loss of a protein in the cells known as SIRT3, induces the proliferation of this disease and thereby, this protein can be an may be a therapeutic target in the development of effective therapies for cancer. The research was led by Dra. Marcia Haigis of the Harvard Medical School, with the participation of Dr. Arkaitz Carracedo, from the Proteomics Laboratory at CIC bioGUNE.

6 Apr 2011

Adipocytes associated with breast cancer could amplify 'aggressive' effect of tumors in obese patients

Apart from its direct effect on health (such as cardiovascular diseases and diabetes), obesity is increasingly suspected of playing a role in the prognosis of breast cancer and, in particular, its propensity to spread. However, no direct cause and effect relationship had been demonstrated until now. This breakthrough has finally been made through the collaborative work of two teams of researchers from Inserm, CNRS and the Université Paul Sabatier.

6 Apr 2011

Editorial cautions against estrogen-only hormone therapy after hysterectomy

An editorial in the April 6 issue of the Journal of the American Medical Association cautions against estrogen-only hormone therapy in women who have had a hysterectomy because of longstanding evidence that it raises the risk of breast cancer.

6 Apr 2011

Scientists uncover SREBP-2 role in autophagy and cholesterol generation

Not all cholesterol is bad. Every cell requires it for growth - they either have to get cholesterol somewhere or they die. In a new study published April 6 in the journal Cell Metabolism, researchers from Sanford-Burnham Medical Research Institute and their collaborators found that a protein sensor known to balance cholesterol sources can also access a previously underappreciated cellular fat storage depot.

6 Apr 2011

FDA approves NeuroVasx cPAX Aneurysm Treatment System

NeuroVasx announced today that the FDA has approved the cPAX Aneurysm Treatment System as a Humanitarian Use Device for the treatment of large, giant and wide-neck cerebral aneurysms, which are typically the most difficult to treat. The HDE allows for the treatment of up to 4,000 patients per year in the U.S.

6 Apr 2011

More than 900 young Britons diagnosed with the deadliest form of skin cancer each year

Each day more than two people under 35 in Britain are diagnosed with malignant melanoma - the deadliest form of skin cancer - according to new figures from Cancer Research UK.

6 Apr 2011

Caliper's CDAS unit enters cancer research collaboration with Denver-based CHI

Caliper Life Sciences, Inc., a leading provider of tools and services for drug discovery and life-sciences research, today announced that its Caliper Discovery Alliances and Services unit has formed a research collaboration with Denver-based Catholic Health Initiatives, one of the nation's largest health systems.

6 Apr 2011

Genzyme, Isis present mipomersen phase 3 study data in severe heFH at ACC meeting

Genzyme Corp., a subsidiary of sanofi-aventis Group, and Isis Pharmaceuticals Inc. announced today that data from two phase 3 studies of mipomersen in patients who had high cholesterol levels while on lipid-lowering therapy were presented at the American College of Cardiology's 60th Annual Scientific Session.

6 Apr 2011

Estrogen only hormone replacement not so risky after 50’s: Study

According to a new study hormone therapy may not be as risky for elder women as earlier thought. This comes from the Women's Health Initiative, a federally funded trial that tracked thousands of women taking hormones or placebo pills for years. The WHI looked at women who have had hysterectomies or have had their uterus removed and thus can take estrogen unaccompanied by another hormone, progestin. It found that a heightened risk of stroke from taking estrogen faded with time, while a reduced risk of breast cancer held steady.

5 Apr 2011

Patients prescribed high doses of pain medications at higher risk of overdose: Study

According to a study published in the April 6 issue of the Journal of the American Medical Association JAMA, receiving higher prescribed doses of opioid prescriptions is associated with an increased risk of opioid overdose death, but receiving both as-needed and regularly scheduled doses is not associated with overdose risk.

5 Apr 2011

Zebrafish research suggests new drug targets and markers to help treat melanoma

Thanks to the zebrafish, there is new hope for people with melanoma, an aggressive skin cancer that is responsible for approximately 8,700 deaths each year in the United States.

5 Apr 2011