Cancer News and Research

Latest Cancer News and Research

FDA grants Biovest's BiovaxID vaccine Orphan Drug Designation for mantle cell lymphoma

Biovest International, Inc. today announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation to BiovaxID®, Biovest's personalized cancer vaccine, for a second lymphoma indication: mantle cell lymphoma. Mantle cell lymphoma is an aggressive and lethal B-cell blood cancer for which there is no current consensus standard-of-care.

26 Jul 2010

AVEO's initiation of AV-299 Phase 2 trial for lung cancer triggers $750,000 milestone payment to XOMA

XOMA Ltd., a leader in the discovery and development of therapeutic antibodies, announced receipt of a $750,000 milestone payment under its collaboration with AVEO Pharmaceuticals, Inc.. The milestone payment resulted from AVEO's recent initiation of a Phase 2 clinical trial to evaluate its AV-299 antibody for the treatment of non-small cell lung cancer. AV-299 is a humanized antibody to hepatocyte growth factor (HGF).

26 Jul 2010

Onyx reports positive results from carfilzomib Phase 2b 003-A1 study in multiple myeloma

Onyx Pharmaceuticals, Inc. today announced positive top-line results from the Phase 2b 003-A1 study of single-agent carfilzomib, a selective, next generation proteasome inhibitor, in patients with relapsed and refractory multiple myeloma.

26 Jul 2010

Vical's prophylactic Vaxfectin-formulated pDNA vaccine effective against HSV-2 in animal model

Vical Incorporated today announced that its prophylactic Vaxfectin®-formulated plasmid DNA (pDNA) vaccine against herpes simplex virus type 2 (HSV-2) protected mice against lethal challenge, provided sterilizing immunity and inhibited viral counts at both the primary and latent infection sites. The Vaxfectin® adjuvant substantially improved vaccine effectiveness. A related vaccine significantly reduced the recurrence of HSV-2 lesions in a therapeutic model using guinea pigs with latent infection.

26 Jul 2010

Aptium Oncology to provide administrative services at new Beth Israel Comprehensive Cancer Center

Offering greater access to cancer care services for Manhattan West Side residents in New York, Beth Israel Medical Center has opened the Beth Israel Comprehensive Cancer Center - West Side Campus in the facility formerly known as St. Vincent's Comprehensive Cancer Center (SVCCC). The facility, which originally opened in 1996, was one of a few Saint Vincent's outpatient services units untouched and left open when the iconic hospital closed its doors on April 30, 2010. An official ribbon-cutting ceremony launched the center on Wednesday, July 14, 2010.

26 Jul 2010

Kindergarten puppet show reduces anxiety of kids with cancer

THE PUPPET SHOW IS PART OF THE BACK-TO-SCHOOL PROGRAM AT DANA-FARBER CANCER INSTITUTE IN BOSTON. IT'S DESIGNED TO REDUCE THE ANXIETY OF CHILDREN LIVING WITH CANCER. LISA SCHERBER (SHER-BURR) HEAD'S UP THE PROGRAM.

26 Jul 2010

Axela acquires Xceed Molecular

Axela Inc., an innovator in systems that multiplex protein biomarker testing in clinical research and diagnostics, has acquired Xceed Molecular, developer of the award-winning Ziplex® System for gene-expression analysis, the Breast Cancer Prognostic Assay, and Colon Cancer Xpress chip. The new Axela will be introduced at the 2010 American Association of Clinical Chemistry (AACC) annual meeting and Clinical Lab Expo, which takes place July 25 – 29 at the Anaheim Convention Center in California.

26 Jul 2010

IDC secures $32 million in Series B financing

Immune Design Corp. (IDC), a privately held biotechnology company focused on developing novel vaccines and immunotherapies for infectious disease and cancer, announced today that it has secured $32 million in Series B financing. The round was led by ProQuest Investments and was joined by current investors: The Column Group, Versant Ventures, and Alta Partners. The Series B financing brings the total amount of equity capital raised by IDC to $50 million since its inception in 2008.

26 Jul 2010

Study compares current state of healthcare system in UK and proposed system in US

A comparison of the current state of the healthcare system in the UK and the new system proposed under legislation pushed through by Barack Obama's government, shows some surprising results. The review is published in the Journal of the Royal Society of Medicine (JRSM).

26 Jul 2010

Council seeks to limit medical resident working hours for improved patient care

As the Accreditation Council for Graduate Medical Education seeks to improve patient care by further limiting the hours worked by medical residents, the Journal of Surgical Research will published a new study online on Monday reporting that outcomes in two common surgeries - appendectomy and laparoscopic cholecystectomy - were similar among residents who had worked less than 16 hours and those who had worked more than 16 hours.

26 Jul 2010

School program to help children continue normal educational activities during treatment

Treatment for cancer and other catastrophic disease can last months or years and often makes it impossible for young patients to keep up with their local school curriculum. Teachers in the St. Jude School Program Presented by Target help patients continue their normal educational activities while away from their local schools. They are also part of the health care team that provides opportunities to continue normal educational activities through homebound or hospital-bound educational services. In addition, the team provides school re-entry services to ease the transition back to the community school.

26 Jul 2010

Asuragen reports collaborative study results of advanced PCR-based molecular profiling of FMR1 gene

Asuragen, Inc. announced today the results from two collaborative studies, one with the University of California Davis M.I.N.D. Institute and another with Rush University Medical Center, that demonstrate comprehensive molecular profiling of the Fragile X Mental Retardation (FMR1) gene using advanced PCR-based methods.

26 Jul 2010

No such thing as “safe” cigarettes

In a new development a 12-member US panel is debating over the issue of menthol cigarettes being more addictive. If the results go against the cigarettes Australia too will have to ban the sale of such cigarettes. This would mean a significant loss to Alpine cigarettes and imported brands such as Kool, Virginia Slims and Salem.

26 Jul 2010

Obesity linked to rising womb cancer in women: Report

According to a new report from the Charity Cancer Research (CCR) in Britain, the number of women with womb cancer or uterine cancer is on the rise and obesity may be a clue to such rise.

26 Jul 2010

Glioblastomas patients with affected stem cell niche experience progression-free survival

Patients with deadly glioblastomas who received high doses of radiation that hit a portion of the brain that harbors neural stem cells had double the progression-free survival time as patients who had lower doses or no radiation targeting the area, a study from the Radiation Oncology Department at UCLA's Jonsson Comprehensive Cancer Center has found.

26 Jul 2010

North Shore-LIJ Health System seeks oropharynx patients for phase I clinical trial

The North Shore-LIJ Health System Department of Radiation Medicine announced today it is seeking patients with cancer of the oropharynx (back of the mouth) to participate in a Phase I clinical trial.Subjects must be newly diagnosed and not have undergone any previous treatment. Further, their cancer must be unassociated with the human papilloma virus (HPV-negative), or, if it is HPV-positive, they must be current or former pack-a-day smokers for at least 10 years.

26 Jul 2010

Scientists develop nanoprobe to detect blood vessel growth in tumors

Formation of new blood vessels, also known as angiogenesis, is crucial for sustained tumor growth and cancer metastasis. Recently, clinically available therapies to suppress the growth of these vessels have been available to improve patient survival in some cancer types. Accurate detection and quantification of blood vessel growth using nonsurgical methods would greatly complement current therapies and allow physicians to quickly assess treatment regimens and adjust them as necessary. In the work published in the August issue of Experimental Biology and Medicine, Kessinger and coworkers have incorporated nanotechnology, material science, and the clinical imaging modality MRI, to create a nanosized probe capable of noninvasively visualizing and quantifying the blood vessel growth in tumors in a preclinical model.

26 Jul 2010

Neu5Gc in drugs provokes strong immune response

Researchers at the University of California, San Diego School of Medicine have discovered that a kind of sugar molecule common to chimpanzees, gorillas and other mammals but not found in humans provokes a strong immune response in some people, likely worsening conditions in which chronic inflammation is a major issue.

26 Jul 2010

British adults support removal of tobacco displays in shops, ban on cigarette vending machines: Survey

Three quarters of British adults support the removal of shop displays of tobacco (73 per cent) and a complete ban on cigarette vending machines (77 per cent) according to a new survey commissioned by Cancer Research UK this weekend.

26 Jul 2010

Research roundup: Hospital emergency room HIV screenings; Medical device reviews; Health law impact on docs and hospitals

Physician Satisfaction With Chronic Care Processes: A Cluster-Randomized Trial Of Guided Care - The authors randomly assigned teams of physicians and their chronically ill older patients into groups that either provided Guided Care - an educated registered nurse works with a primary care practice team to enhance quality of care - or usual care. One year later, they measured "physicians' satisfaction with chronic care processes, time spent on chronic care, knowledge of their chronically ill older patients, and care coordination provided by physicians and office staff."

26 Jul 2010

Cancer News and Research

Latest Cancer News and Research

FDA grants Biovest's BiovaxID vaccine Orphan Drug Designation for mantle cell lymphoma

AVEO's initiation of AV-299 Phase 2 trial for lung cancer triggers $750,000 milestone payment to XOMA

Onyx reports positive results from carfilzomib Phase 2b 003-A1 study in multiple myeloma

Vical's prophylactic Vaxfectin-formulated pDNA vaccine effective against HSV-2 in animal model

Aptium Oncology to provide administrative services at new Beth Israel Comprehensive Cancer Center

Kindergarten puppet show reduces anxiety of kids with cancer

Axela acquires Xceed Molecular

IDC secures $32 million in Series B financing

Study compares current state of healthcare system in UK and proposed system in US

Council seeks to limit medical resident working hours for improved patient care

School program to help children continue normal educational activities during treatment

Asuragen reports collaborative study results of advanced PCR-based molecular profiling of FMR1 gene

No such thing as “safe” cigarettes

Obesity linked to rising womb cancer in women: Report

Glioblastomas patients with affected stem cell niche experience progression-free survival

North Shore-LIJ Health System seeks oropharynx patients for phase I clinical trial

Scientists develop nanoprobe to detect blood vessel growth in tumors

Neu5Gc in drugs provokes strong immune response

British adults support removal of tobacco displays in shops, ban on cigarette vending machines: Survey

Research roundup: Hospital emergency room HIV screenings; Medical device reviews; Health law impact on docs and hospitals

Industry Focus: Cell & Gene Therapy eBook

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Scaling organ‑chip technology for human‑relevant drug discovery

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Cancer News and Research

Latest Cancer News and Research

Industry Focus: Cell & Gene Therapy eBook

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

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