Cardiovascular Disease

Cardiovascular disease involves the heart and vessels and is the number one killer in the U.S. accounting for nearly 30-percent of all deaths. Cardiovascular disease has a number of forms but the most common are myocardial infarction and angina pectoris which affect the heart itself.

What is Cardiovascular Disease?

Diseases of disorders of this system are termed cardiovascular diseases. Cardiovascular diseases kill an estimated 17 million people worldwide each year. Majority of these are due to heart attacks and strokes.

What is Microvascular Endothelial Dysfunction?

Cardiovascular Drugs

Cardiovascular Disease Research

Causes and Symptoms of Hypoplastic Left Heart Syndrome

Cardiovascular Benefits of Blueberries

Non-Communicable Diseases

Lowering Risk for Cardiovascular Disease

Cardiovascular Disease Diagnosis

Latest Cardiovascular Disease News and Research

Financial strain and food insecurity drive accelerated cardiac aging

A novel analysis investigating the contribution of social determinants of health (SDoH) to cardiac aging has found that financial strain and food insecurity are the strongest drivers of accelerated biological aging and increased mortality risk.

18 Dec 2025

Extra sleep after the autumn clock change linked to reduced demand for NHS health services

The week after the autumn clock change is associated with a reduction in demand for NHS services for sleep disorders, cardiovascular disease, anxiety, depression, and psychiatric conditions in England, finds a study in the Christmas issue of The BMJ.

18 Dec 2025

Couples-based programs boost heart-healthy behaviors

Research highlights the need for couple-based interventions in heart disease to focus on emotional support and relationship quality for better health outcomes.

18 Dec 2025

Strong heart health lowers long-term death risk in cancer survivors

Higher Life’s Simple 7 cardiovascular health scores were associated with lower long-term all-cause and cancer mortality in cancer survivors from a large Italian cohort. Inflammation, resting heart rate, and vitamin D statistically explained a substantial share of these associations, supporting shared cardiometabolic pathways across cancer and cardiovascular disease.

17 Dec 2025

Intermittent fasting edges daily calorie cuts for blood pressure and long-term cardiovascular risk estimates

In a real-world registry study of adults with overweight or obesity, 5:2 intermittent fasting and daily calorie restriction both improved blood pressure over 12 weeks. Intermittent fasting produced modestly greater reductions in systolic and pulse pressure and a larger drop in BMI-based 30-year cardiovascular risk scores, without superior lipid or glycaemic effects.

17 Dec 2025

Stress may help explain why patients with depression are at higher risk of cardiovascular disease

Patients with depression are at higher risk of cardiovascular disease, and a new study suggests that stress may help explain why.

17 Dec 2025

Baloxavir reduces flu-related hospitalizations more than oseltamivir

A study reveals baloxavir outperforms oseltamivir in reducing hospitalization rates for influenza, highlighting its clinical advantages in outpatient settings.

17 Dec 2025

Researchers identify partner protein that supports appetite regulating-protein

A protein essential to the human body for managing energy and regulating appetite relies on a partner protein, according to new research, and the findings could help researchers better understand genetic obesity.

16 Dec 2025

Relationship quality impacts heart health, study shows

With heart disease as the leading cause of death worldwide, there is growing recognition that recovery is not only physical but also emotional and social. A new study shows that strong and supportive relationships can indeed improve heart health for individuals with cardiovascular disease.

16 Dec 2025

New data supports link between gum disease and heart disease

There is increasing evidence that gum disease is associated with increased risk of cardiovascular events, including heart attack, stroke, atrial fibrillation, heart failure and cardiometabolic health conditions. Effective prevention and treatment of gum disease, also called periodontal disease, could potentially decrease the burden of cardiovascular disease, according to a new scientific statement published today in the American Heart Association's flagship journal Circulation.

16 Dec 2025

Mediterranean diet and healthy habits improve cancer survival rates

Being more physically active, following a balanced diet, not smoking, and keeping body weight and blood pressure under control: the same habits that protect the heart also prove decisive after a cancer diagnosis.

16 Dec 2025

Single-pill combination medications may simplify treatment for adults with high blood pressure

Taking one pill that combines two or more blood pressure medications may help adults with high blood pressure (also known as hypertension) lower their blood pressure level faster and more effectively than taking multiple medications separately, and it may also reduce the risk of heart attack and stroke, according to a new scientific statement published today in the American Heart Association's journal Hypertension.

15 Dec 2025

E-cigarette use is linked to higher heart attack risk, especially in former smokers

This systematic review and meta-analysis examined whether electronic cigarette use is associated with myocardial infarction and stroke, synthesizing evidence from 12 observational studies. The analysis found higher odds of myocardial infarction among e-cigarette users, particularly former smokers, while no significant associations were observed among exclusive never-smokers.

14 Dec 2025

Swapping high-carb snacks for tree nuts cuts food cravings in young adults at metabolic risk

Daily replacement of typical high-carbohydrate snacks with mixed tree nuts for 16 weeks reduced cravings for sweets and fast foods in young adults with early metabolic syndrome risk. This dietary swap improved overall diet quality, measured by the Healthy Eating Index, without increasing body weight or altering short-term glycaemic markers.

14 Dec 2025

Lowering blood sugar reduces heart risk in prediabetes

Lowering blood sugar levels halves the likelihood of serious heart problems in people with prediabetes.

12 Dec 2025

Indiana University physician joins FDA panel on male hormone therapy

Helen Bernie, DO, MPH, assistant professor of urology at Indiana University School of Medicine, will participate in an expert panel on testosterone replacement therapy and men's health to be held Wednesday, Dec. 10, by the U.S. Food and Drug Administration. Bernie's role on the panel is that of a clinical expert on men's reproductive health, which is the focus of both her practice and academic research.

12 Dec 2025

Glycation stress drives aortic stiffening through oxidative stress and senescence

A new research paper was published in Volume 17, Issue 11 of Aging-US on November 14, 2025, titled "Methylglyoxal-induced glycation stress promotes aortic stiffening: putative mechanistic roles of oxidative stress and cellular senescence."

12 Dec 2025

Increased epicardial fat volume linked to greater myocardial injury after infarction

Increased volume of epicardial adipose tissue, detected by cardiovascular imaging, was found to be associated with greater myocardial injury after a myocardial infarction.

12 Dec 2025

How specific foods reshape oxidative stress responses during and after high-intensity training

Carbohydrate-rich foods blunt acute oxidative stress during fasted high-intensity exercise, while polyphenol-rich foods accelerate early recovery by reducing post-exercise ROS. Findings highlight how nutrient timing shapes redox responses in sedentary young women undergoing resistance-circuit HIIT.

11 Dec 2025

What happens to your body when you eat takeaway food too often?

This study of 8,556 US adults shows that frequent takeaway food consumption is associated with a higher energy-adjusted Dietary Inflammatory Index and adverse cardiometabolic markers. The findings suggest that reducing takeaway intake and lowering dietary inflammatory potential may improve long-term cardiometabolic health.

11 Dec 2025