Chemotherapy News and Research

Latest Chemotherapy News and Research

Drug AMD-3100 may help cancer patients who need stem cell transplants

A new drug may help cancer patients mobilize the cells necessary to restore their blood-forming system after high-dose chemotherapy, according to results from a clinical trial at the Kimmel Cancer Center at Thomas Jefferson University Hospital in Philadelphia and at other centers across the nation.

19 Sep 2005

Does surgery induce angiogenesis in dormant breast cancer?

Analysis of breast-cancer relapse patterns from two independent databases provides indirect evidence for the theory that surgery to remove the primary tumor may initiate formation of a new blood supply (angiogenesis) in formerly dormant metastases, accounting for a pattern of early relapse in younger women.

12 Sep 2005

Combining radiation, chemotherapy and liver transplantation increases survival in bile duct cancer patients

A new treatment for patients with a type of bile duct cancer promises a greater chance at survival by combining radiation, chemotherapy and liver transplantation, Mayo Clinic physicians report in the September issue of the Annals of Surgery.

12 Sep 2005

Giving patients both chemotherapy and radiation in the beginning of treatment may help cancer patients live longer

While researchers have learned in the last decade that combining chemotherapy with radiation is better than radiation alone for treating non-small cell lung cancer patients with locally advanced disease - cancer confined to the lungs - finding the right combination of drugs - and the best timing of treatment - has been tricky.

6 Sep 2005

New findings suggest balancing Chk1 activity will produce less toxic cancer drugs

A study published by The Burnham Institute in the September edition of Molecular Cell reports that a cell-cycle checkpoint protein, known to be activated by an important class of anticancer drugs, may play crucial roles in both the hampering of therapeutic actions and aiding cancer cells to "recover" and start dividing again after treatment with these drugs.

5 Sep 2005

Rev/Dex combo looks like a breakthrough treatment for multiple myeloma

Mayo Clinic Cancer Center investigators report that combination therapy with lenalidomide (Revlimid) and dexamethasone (combination is called Rev/Dex) looks like a breakthrough treatment for multiple myeloma. Results of a Phase II clinical trial were published online Aug. 23 in Blood.

1 Sep 2005

Complex chemotherapy cocktails offers pluses, minuses in advanced endometrial cancer

Complex chemotherapy cocktails offer about one extra month of life to patients with end-stage endometrial cancer but also can result in severe, possibly fatal, side effects, according to the first systematic review of studies addressing the topic.

1 Sep 2005

Compound called GRN163L blocks lung cancer

Researchers at UT Southwestern Medical Center have found a compound that shows promise as a way to block the spread, or metastasis, of lung cancer.

1 Sep 2005

Carbohydrate known as OGT2378 inhibits tumor growth

A non-toxic chemical compound that prevents cancer cells from producing a critical membrane component has been shown to suppress tumor growth and tumor size in mice without unwanted side effects, according to researchers at the Children’s National Medical Center in Washington, D.C.

30 Aug 2005

Toxicity from chemotherapy in lung cancer patients could help predict treatment efficacy

Chemotherapy is standard treatment for patients with advanced non-small cell lung cancer, although benefits are modest and toxicity substantial. Massimo Di Maio and colleagues hypothesised that neutropenia, a haematological toxicity, could be a predictor of drug activity and treatment efficacy.

30 Aug 2005

Dental problems caused by radiation, chemotherapy should be treated before a child undergoes immunosuppression as part of bone marrow transplantation therapy

Many children who undergo bone marrow transplantation (BMT) as part of cancer treatment already have dental abnormalities that leave them vulnerable to potentially life-threatening bacterial infections, according to investigators at St. Jude Children's Research Hospital. A report on this study appears in the prepublication online edition of Bone Marrow Transplantation.

29 Aug 2005

High-dose anticancer chemotherapy and total body irradiation during childhood can damage developing teeth

Research published by the University of Helsinki, Finland, indicates that cytostatic and radiation therapies administered before stem cell transplantation often damage children's permanent teeth.

29 Aug 2005

Discovery may significantly advance the treatment of cancers and infectious diseases

Current treatments frequently achieve only limited results with these types of diseases, which affect hundreds of thousands of Canadians.

29 Aug 2005

First clinical trial of a biologic nanoparticle designed to give back to cancer patients the tumor-busting gene they have lost

The phase I clinical study will enroll 20 patients with advanced solid cancers (including most common tumor types), and is the culmination of more than a decade of work by a team of researchers led by Professor Esther H. Chang, Ph.D. at the Lombardi Comprehensive Cancer Center.

25 Aug 2005

Sentinel node biopsy, when performed before chemotherapy to shrink the tumor, is very reliable

New breast cancer research shows for the first time that even women with large breast tumors can benefit from a less invasive biopsy method that has been reserved until now for women with small breast cancers.

23 Aug 2005

Young breast cancer sufferers need more fertility advice before treatment

According to new research led by the University of New South Wales (UNSW), Australia, 25% of young breast cancer sufferers say that there was no discussion of fertility issues at the time of diagnosis, despite the possibility of infertility after treatment.

22 Aug 2005

Experimental vaccine can prime the immune system to help fight an aggressive form of lymphoma

Researchers at The University of Texas M. D. Anderson Cancer Center and the National Cancer Institute have found that an experimental vaccine can prime the immune system to help fight an aggressive form of lymphoma, even though prior therapy had eliminated virtually all of the B cells thought necessary to mount such a defense.

22 Aug 2005

Nearly one-third of former brain tumor patients require special education services

Children who survive brain cancer struggle for years with the malevolent echo of the disease and its treatment, according to a new study from the Stanford University School of Medicine and Lucile Packard Children's Hospital.

22 Aug 2005

Medulloblastoma irradiation may impair reading skills in young children

Irradiation therapy for the brain cancer medulloblastoma is more likely to impair IQ and reading skills of younger children than older children even if the dose of radiation is reduced, according to the results of the largest study of its kind, conducted by investigators at St. Jude Children's Research Hospital, Texas Children's Cancer Center (Houston) and Royal Children's Hospital (Melbourne, Australia).

22 Aug 2005

Interferon selectively kills colon cancer cells when combined with irinotecan chemotherapy agent

Johns Hopkins Kimmel Cancer Center scientists have found that interferon, used for 30 years to treat blood cancers, multiple sclerosis and hepatitis, selectively kills colon cancer cells when combined with another standard chemotherapy agent.

16 Aug 2005

Chemotherapy News and Research

Latest Chemotherapy News and Research

Drug AMD-3100 may help cancer patients who need stem cell transplants

Does surgery induce angiogenesis in dormant breast cancer?

Combining radiation, chemotherapy and liver transplantation increases survival in bile duct cancer patients

Giving patients both chemotherapy and radiation in the beginning of treatment may help cancer patients live longer

New findings suggest balancing Chk1 activity will produce less toxic cancer drugs

Rev/Dex combo looks like a breakthrough treatment for multiple myeloma

Complex chemotherapy cocktails offers pluses, minuses in advanced endometrial cancer

Compound called GRN163L blocks lung cancer

Carbohydrate known as OGT2378 inhibits tumor growth

Toxicity from chemotherapy in lung cancer patients could help predict treatment efficacy

Dental problems caused by radiation, chemotherapy should be treated before a child undergoes immunosuppression as part of bone marrow transplantation therapy

High-dose anticancer chemotherapy and total body irradiation during childhood can damage developing teeth

Discovery may significantly advance the treatment of cancers and infectious diseases

First clinical trial of a biologic nanoparticle designed to give back to cancer patients the tumor-busting gene they have lost

Sentinel node biopsy, when performed before chemotherapy to shrink the tumor, is very reliable

Young breast cancer sufferers need more fertility advice before treatment

Experimental vaccine can prime the immune system to help fight an aggressive form of lymphoma

Nearly one-third of former brain tumor patients require special education services

Medulloblastoma irradiation may impair reading skills in young children

Interferon selectively kills colon cancer cells when combined with irinotecan chemotherapy agent

Cancer Research eBook

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Chemotherapy News and Research

Latest Chemotherapy News and Research

Cancer Research eBook

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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