Chromosome News and Research

Latest Chromosome News and Research

Low levels of dietary folate linked to sperm abnormalities

Healthy men who report lower levels of the nutrient folate in their diets have higher rates of chromosomal abnormalities in their sperm, according to a new study by researchers at the University of California, Berkeley, and the Lawrence Berkeley National Laboratory.

20 Mar 2008

New study confirms that PROGENSA PCA3 can improve accuracy of prostate cancer diagnosis

New clinical data from a study of 570 men published in the peer-reviewed Journal of Urology support the use of PROGENSA PCA3 as a tool for diagnosing prostate cancer. The study confirms that PROGENSA PCA3, the world's first gene-based urine test to help detect prostate cancer, can provide clinicians with valuable information that helps guide diagnosis.

20 Mar 2008

Levels of folate in men's diets is linked to chromosomal abnormalities in their sperm

Researchers have found an association between a vitamin found in leafy green vegetables, fruit and pulses [1] and levels of chromosomal abnormalities in men's sperm.

20 Mar 2008

Disruption of the Contactin 4 gene on chromosome 3 may be linked to autism spectrum disorder

Eli Hatchwell, M.D., Ph.D., Associate Professor of Pathology at Stony Brook University Medical Center, and colleagues have found that a disruption of the Contactin 4 gene on chromosome 3 may be linked to autism spectrum disorder (ASD).

20 Mar 2008

On the trail of rogue genetically modified pathogens

Bacteria can be used to engineer genetic modifications, thereby providing scientists with a tool to combat many challenges in areas from food production to drug discovery.

18 Mar 2008

Potential new neuronal tumor suppressor

In a G&D paper published online ahead of its April 1 print publication date, Dr. William Kaelin (Dana Farber Cancer Institute) and colleagues identify a potential new neuronal tumor suppressor.

18 Mar 2008

Penn researchers identify first sex chromosome gene involved in meiosis and male infertility

A team of scientists led by University of Pennsylvania veterinary researchers have identified a gene, TEX11, located on the X chromosome, which when disrupted in mice renders the males sterile and reduces female fecundity.

17 Mar 2008

Genomic tool helps select best eggs for IVF

A research team supervised by Universite Laval scientist Marc-Andre Sirard has identified genetic markers that allow the selection of eggs with the best chance of leading to successful pregnancy after in vitro fertilization (IVF).

13 Mar 2008

Nuclear protein SATB1 triggers aggressive breast cancer

SATB1 is a nuclear protein well known for its crucial role in regulating gene expression during the differentiation and activation of T cells, making it a key player in the immune system.

13 Mar 2008

New genetic finding on Rett syndrome

The first comprehensive analysis of the clinical effects of genetic mutations involved in Rett syndrome will enable affected families to receive a more accurate indication of their child's prognosis.

12 Mar 2008

Scientists characterizes novel regulator of chromosome function

The Stowers Institute's Workman Lab has shed new light on a novel histone acetyltransferase protein complex called ATAC.

11 Mar 2008

Colorectal cancer gene found

Case Western Reserve University School of Medicine researchers published a study in the March 7th issue of The American Journal of Human Genetics identifying the hereditary components of colorectal cancer (CRC.)

10 Mar 2008

Prader-Willi syndrome - new genetic clues

A new mouse model for a genetic cause of obesity has been developed by scientists at the Stanford University School of Medicine and Lucile Packard Children's Hospital.

6 Mar 2008

New genetic marker of risk for breast cancer discovered

An international group of investigators led by scientists at Memorial Sloan-Kettering Cancer Center (MSKCC) and the National Cancer Institute has identified a new genetic marker of risk for breast cancer.

4 Mar 2008

Genetic variations increase risk of anxiety disorders

Massachusetts General Hospital (MGH) researchers - in collaboration with scientists at the University of California at San Diego and Yale University - have discovered perhaps the strongest evidence yet linking variation in a particular gene with anxiety-related traits.

4 Mar 2008

Protein protects lung cancer cells from efforts to fix or kill them

A protein that helps lung cancer cells thrive appears to do so by blocking healthy cells' ability to fix themselves when radiation or chemicals such as nicotine damage their DNA, according to a University of Florida study to be published Friday (Feb. 29) in the journal Molecular Cell.

28 Feb 2008

Enzyme Cdk1 may lead to new cancer therapies

With a four-year, $707,000 grant from the American Cancer Society, Yanchang Wang, assistant professor of biomedical sciences in the Florida State University College of Medicine, hopes to learn how a particular enzyme could possibly help put the brakes on the runaway cell division process that occurs in many forms of cancer.

27 Feb 2008

Genetic mutation linked to peripheral artery disease

The finding, appearing online in the journal Circulation, is the first to document a genetic mutation linked to PAD. Although the work was done in mice, researchers say it is likely to give them new insight into how PAD develops and progresses in humans.

26 Feb 2008

Curcumin reduces heart enlargement and may prevent heart failure

Eating curcumin, a natural ingredient in the spice turmeric, may dramatically reduce the chance of developing heart failure, researchers at the Peter Munk Cardiac Centre of the Toronto General Hospital have discovered.

22 Feb 2008

Smoking's effects on genes may play a role in lung cancer development and survival

Smoking plays a role in lung cancer development, and now scientists have shown that smoking also affects the way genes are expressed, leading to alterations in cell division and regulation of immune response.

21 Feb 2008