Chromosome News and Research

Latest Chromosome News and Research

Study is the first to identify involvement of chromosome 21 in developmental regression autism

A new Cincinnati Children's Hospital Medical Center study links regions of two chromosomes to susceptibility for a type of autism characterized by regression in development. Developmental regression can include the loss of previously acquired language, social skills or both.

8 Jun 2005

Computer simulation helps understand DNA transcription process

New York University chemists have employed a computer simulation whose results have enhanced scientific understanding of the DNA transcription process. The study, funded by the National Institutes of Health, appears in the June 7 issue of the Proceedings of the National Academy of Sciences.

5 Jun 2005

Scientists have uncovered the structure of a network of proteins that help regulate the life cycle of cells

Scientists at Memorial Sloan-Kettering Cancer Center (MSKCC) have uncovered the structure of a network of proteins that help regulate the life cycle of cells. Understanding the network's physical layout is an important step toward learning its precise function, and in finding ways to correct flaws in the system that could lead to cancer.

2 Jun 2005

The bacteria that cause food poisoning, bubonic plague, and whooping cough all deploy the same weapon to infect the body

A molecular "syringe" sticks out of the bacteria, pokes a hole in a nearby cell, and squirts in venomous proteins that hijack the cell's machinery.

2 Jun 2005

Bald men can blame mum!

Despite an enormous range of treatments, obscure lotions and tinctures there appears to be very few successful counter-measures for hair loss in men. Beginning with receding hairlines, every second man suffers from hair loss to some degree, and it has always been suspected that hereditary factors are important in causing hair loss.

22 May 2005

Disease progression model of pancreatic cancer developed

Building on previous work, researchers at the University of Pennsylvania School of Medicine have developed an animal model of pancreatic cancer that closely mimics disease progression in humans. From this, they hope to develop new treatments for this deadly disease.

20 May 2005

Lower doses of chemo just as effective in childhood cancers

In the latest research into treating a common childhood cancer, paediatric oncologist Allen Chauvenet, is optimistic that the long-term side effects that survivors experience as they grow into adulthood can be reduced.

17 May 2005

Deletion on chromosome 11q may guide decision to use chemotherapy for neuroblastoma

When genes are deleted on a particular section of chromosome 11, the result is an aggressive form of the childhood cancer neuroblastoma. A new study suggests that detecting this genetic deletion during the initial evaluation of children with neuroblastoma may indicate to physicians that they should recommend a more aggressive regimen of chemotherapy to fight the cancer.

16 May 2005

Laboratory model of immune system overcomes ethical constraints on studies of hematopoietic stem cells in humans

Scientists at St. Jude Children’s Research Hospital have joined with colleagues at several other institutions to develop a laboratory model of the human immune system. This model will allow scientists to study ways for improving the results of hematopoietic stem cell (HSC) transplantation without putting patients at risk.

10 May 2005

Scientists take aim at virulent bacteria by decoding machinery of key control enzyme

By deciphering the ingenious mechanism used by a particular enzyme to modify bacterial chromosome chemistry, scientists have come a step closer to designing a new kind of drug that could stop virulent bacterial infections in their tracks. Their research will be published in the May 6 issue of the journal Cell.

5 May 2005

Mosaic Analysis with Double Markers (MADM) - A powerful new tool to study diseases and genetics

A powerful laboratory technique used by fruit fly geneticists for more than a decade is now available to scientists studying genes and diseases in mice.

5 May 2005

Researchers make new advances in determining the structure of all possible DNA sequences

Oregon State University researchers have made significant new advances in determining the structure of all possible DNA sequences – a discovery that in one sense takes up where Watson and Crick left off, after outlining in 1953 the double-helical structure of this biological blueprint for life.

3 May 2005

Age-related macular degeneration is triggered, possibly by an infection

Age-related macular degeneration, the leading cause of blindness in the elderly, occurs when a common inherited gene variation is triggered, possibly by an infection, according to a new study led by researchers at Columbia University Medical Center and the University of Iowa, with an international research team.

1 May 2005

Pollutants appear to have an affect on sex chromosome

A team of researchers from Lund University in Sweden have found that exposure to a class of environmental pollutants can change the ratio of sperm carrying male and female chromosomes.

1 May 2005

Family history DNA sleuths run risk of uncovering infertility

A simple DNA test that is available commercially to help people establish their ancestry could in fact disclose male infertility claims a new study from the University of Leicester.

28 Apr 2005

Abnormal cell division explained

Why do some cancer cells divide not into two, as cells are supposed to do in mitosis, but into three-four new cells that look thoroughly abnormal? This question was raised as early as the 1890s by the German tumor researcher David Hansemann, who could observe the strange mitosis even using the microscopes of his day. Now another David, Lund University researcher David Gisselsson, has found an answer.

28 Apr 2005

Increasing benefit seen in novel drug AMN107, that treats Gleevec resistance

An investigational drug is producing powerful responses in patients resistant to Gleevec, the targeted therapy that helps most people diagnosed with chronic myeloid leukemia (CML), an international research team headed by investigators at The University of Texas M. D. Anderson Cancer Center is reporting.

23 Apr 2005

Enzyme that helps trigger the development of leukemia

Scientists at the University of North Carolina at Chapel Hill have identified an enzyme that helps trigger the development of leukemia, a cancer of blood cells.

21 Apr 2005

New gene linked to familial cancer

Scientists have identified a new gene that appears to be linked to a small but significant percentage of familial cancer cases – as well as seemingly randomly occurring malignancies.

20 Apr 2005

Ancient protein could be critical to stopping the uncontrolled division of tumor cells that cause cancer

Molecular Biology and Microbiology professor Mark Muller has found that the protein, called MKRN1, promotes the destruction of an enzyme called telomerase that enables rapid duplication of cells. While researchers have known for years that healthy cells repress telomerase, they haven't understood why.

19 Apr 2005

Chromosome News and Research

Latest Chromosome News and Research

Study is the first to identify involvement of chromosome 21 in developmental regression autism

Computer simulation helps understand DNA transcription process

Scientists have uncovered the structure of a network of proteins that help regulate the life cycle of cells

The bacteria that cause food poisoning, bubonic plague, and whooping cough all deploy the same weapon to infect the body

Bald men can blame mum!

Disease progression model of pancreatic cancer developed

Lower doses of chemo just as effective in childhood cancers

Deletion on chromosome 11q may guide decision to use chemotherapy for neuroblastoma

Laboratory model of immune system overcomes ethical constraints on studies of hematopoietic stem cells in humans

Scientists take aim at virulent bacteria by decoding machinery of key control enzyme

Mosaic Analysis with Double Markers (MADM) - A powerful new tool to study diseases and genetics

Researchers make new advances in determining the structure of all possible DNA sequences

Age-related macular degeneration is triggered, possibly by an infection

Pollutants appear to have an affect on sex chromosome

Family history DNA sleuths run risk of uncovering infertility

Abnormal cell division explained

Increasing benefit seen in novel drug AMN107, that treats Gleevec resistance

Enzyme that helps trigger the development of leukemia

New gene linked to familial cancer

Ancient protein could be critical to stopping the uncontrolled division of tumor cells that cause cancer

One Health, One Mission: The World Organisation for Animal Health on the AMR Frontline

Uniting Against Resistance: The World Health Organization for World Antimicrobial Awareness Week 2023

Tackling Antimicrobial Resistance: A Conversation with Dr. Beverley Isherwood

Chromosome News and Research

Latest Chromosome News and Research

One Health, One Mission: The World Organisation for Animal Health on the AMR Frontline

Uniting Against Resistance: The World Health Organization for World Antimicrobial Awareness Week 2023

Tackling Antimicrobial Resistance: A Conversation with Dr. Beverley Isherwood

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