Chromosome News and Research

Latest Chromosome News and Research

Teva's SYNRIBO for injection receives FDA approval for home administration

Teva Pharmaceutical Industries Ltd. (NYSE:TEVA) today announced that the U.S. Food and Drug Administration (FDA) has approved SYNRIBO® (omacetaxine mepesuccinate) for injection, for subcutaneous use, to include home administration, and also approved a related Medication Guide and Instructions for Use.

6 May 2014

Puzzle in breast cancer solved

In a new study published in Cell Reports, scientists at the Fred Hutchinson Cancer Research Center demonstrate that mice lacking one copy of a gene called CTCF have abnormal DNA methylation and are markedly predisposed to cancer.

5 May 2014

Researchers detect correlation between loss of Y chromosome and risk of cancer mortality

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29 Apr 2014

BRCA gene loss may accelerate cancer-promoting chromosome rearrangements

Inherited mutations in the BRCA1 or BRCA2 tumor suppressor genes are by far the most frequent contributors to hereditary cancer risk in the human population, often causing breast or ovarian cancer in young women of child-bearing age.

29 Apr 2014

Physical activity reduces hippocampal atrophy in elders at genetic risk for Alzheimer's disease

A study of older adults at increased risk for Alzheimer's disease shows that moderate physical activity may protect brain health and stave off shrinkage of the hippocampus- the brain region responsible for memory and spatial orientation that is attacked first in Alzheimer's disease.

25 Apr 2014

91% of Americans know genetic information has important utility in managing health

23andMe, the leading personal genetics company, is celebrating National DNA Day by taking an in-depth look at what Americans know about their DNA and how genetics play a role in our everyday lives. The survey found that 91 percent of Americans know that their genetic information has important utility in managing their health.

23 Apr 2014

Study: Added benefit of turoctocog alfa is not proven

Turoctocog alfa (trade name: NovoEight) has been approved since November 2013 for the prevention and treatment of bleeding in patients with haemophilia A.

23 Apr 2014

SIRT1 protein necessary for telomere elongation and genome integrity during cell reprogramming

Cell reprogramming converts specialised cells such as nerve cells or skin cells towards an embryonic stem cell state. This reversal in the evolutionary development of cells also requires a reversal in the biology of telomeres, the structures that protect the ends of chromosomes; whilst under normal conditions telomeres shorten over time, during cell reprogramming they follow the opposite strategy and increase in length.

22 Apr 2014

RMANJ releases new fertility checklist for early diagnosis and treatment options

With over seven million men and women in the United States impacted by infertility, information about early diagnosis and various infertility treatment options like in vitro fertilization (IVF), preimplantation genetic diagnosis (PGD), and comprehensive chromosome screening (CCS) can offer help to many patients looking to overcome infertility.

22 Apr 2014

Researchers reveal connection between Down syndrome and acute lymphoblastic leukemia

Although doctors have long known that people with Down syndrome have a heightened risk of developing acute lymphoblastic leukemia (ALL) during childhood, they haven't been able to explain why. Now, a team of Dana-Farber Cancer Institute investigators has uncovered a connection between the two conditions.

21 Apr 2014

Study sheds light on how extra chromosome 21 upsets equilibrium of entire genome in Down syndrome

Occurring in about one per eight hundred births, Down syndrome - or trisomy 21 - is the most frequent genetic cause of intellectual disability. It results from a chromosomal abnormality where cells of affected individuals contain a third copy of chromosome 21 (1% of the human genome).

18 Apr 2014

Research sheds new light on the development of HPV-associated cancer

It's long been known that certain strains of human papillomavirus (HPV) cause cancer. Now, researchers at The Ohio State University have determined a new way that HPV might spark cancer development - by disrupting the human DNA sequence with repeating loops when the virus is inserted into host-cell DNA as it replicates.

17 Apr 2014

Findings offer new paths towards improved fertility treatments and development of new contraceptives

Researchers at the Wellcome Trust Sanger Institute have discovered interacting proteins on the surface of the sperm and the egg essential to begin mammalian life. These proteins, which allow the sperm and egg to recognize one another, offer new paths towards improved fertility treatments and the development of new contraceptives.

17 Apr 2014

Genetic evidence confirms role of group of virus-fighting genes in cancer development

Researchers have found a major piece of genetic evidence that confirms the role of a group of virus-fighting genes in cancer development.

15 Apr 2014

Two candidate mTOR therapy biomarkers identified in RCC

Two genes, TSC1 and MTOR, warrant further investigation as biomarkers for treatment benefit with rapalogs in patients with renal cell carcinoma, indicate study results published in Clinical Cancer Research.

14 Apr 2014

Tumor-suppressing protein acts as dimmer switch to dial down gene expression

A tumor-suppressing protein acts as a dimmer switch to dial down gene expression. It does this by reading a chemical message attached to another protein that's tightly intertwined with DNA, a team led by scientists at The University of Texas MD Anderson Cancer Center reported at the AACR Annual Meeting 2014.

11 Apr 2014

Comprehensive genomic analysis of low-grade brain tumors sorts into three categories

Comprehensive genomic analysis of low-grade brain tumors sorts them into three categories, one of which has the molecular hallmarks and shortened survival of glioblastoma multiforme, the most lethal of brain tumors, researchers reported at the American Association for Cancer Research Annual Meeting 2014.

10 Apr 2014

Stressful upbringings can leave imprints on genes of African American children

Stressful upbringings can leave imprints on the genes of children as young as age 9, according to a study led by Princeton University and Pennsylvania State University researchers. Such chronic stress during youth leads to physiological weathering similar to aging.

10 Apr 2014

Research opens new possibilities for blocking runaway cell division in cancer

The structure of a key part of the machinery that allows cells to divide has been identified by researchers at the University of California, Davis -- opening new possibilities for throwing a wrench in the machine and blocking runaway cell division in cancer.

9 Apr 2014

Scientists uncover surprising link between brain development and gene tied to breast cancer

Scientists at the Salk Institute have uncovered details into a surprising-and crucial-link between brain development and a gene whose mutation is tied to breast and ovarian cancer.

9 Apr 2014

Chromosome News and Research

Latest Chromosome News and Research

Teva's SYNRIBO for injection receives FDA approval for home administration

Puzzle in breast cancer solved

Researchers detect correlation between loss of Y chromosome and risk of cancer mortality

BRCA gene loss may accelerate cancer-promoting chromosome rearrangements

Physical activity reduces hippocampal atrophy in elders at genetic risk for Alzheimer's disease

91% of Americans know genetic information has important utility in managing health

Study: Added benefit of turoctocog alfa is not proven

SIRT1 protein necessary for telomere elongation and genome integrity during cell reprogramming

RMANJ releases new fertility checklist for early diagnosis and treatment options

Researchers reveal connection between Down syndrome and acute lymphoblastic leukemia

Study sheds light on how extra chromosome 21 upsets equilibrium of entire genome in Down syndrome

Research sheds new light on the development of HPV-associated cancer

Findings offer new paths towards improved fertility treatments and development of new contraceptives

Genetic evidence confirms role of group of virus-fighting genes in cancer development

Two candidate mTOR therapy biomarkers identified in RCC

Tumor-suppressing protein acts as dimmer switch to dial down gene expression

Comprehensive genomic analysis of low-grade brain tumors sorts into three categories

Stressful upbringings can leave imprints on genes of African American children

Research opens new possibilities for blocking runaway cell division in cancer

Scientists uncover surprising link between brain development and gene tied to breast cancer

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Chromosome News and Research

Latest Chromosome News and Research

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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