Circadian Rhythm News and Research

Latest Circadian Rhythm News and Research

Irregular sleep timing disrupts daily rhythms of our genes

A new study from the University of Surrey, published today in the journal PNAS (Proceedings of the National Academy of Sciences), found that the daily rhythms of our genes are disrupted when sleep times shift.

21 Jan 2014

Higher levels of melatonin may lower risk for developing advanced prostate cancer

Higher levels of melatonin, a hormone involved in the sleep-wake cycle, may suggest decreased risk for developing advanced prostate cancer, according to results presented here at the AACR-Prostate Cancer Foundation Conference on Advances in Prostate Cancer Research, held Jan. 18-21.

19 Jan 2014

Scientists develop strategies focused on diet to treat patients suffering from circadian dysfunctions

Living organisms have adapted to the day-night cycle and, in most cases, they have evolved a "circadian clock". Its effects are not completely known yet but its functioning has been shown to have important metabolic consequences for the body.

16 Jan 2014

Low testosterone levels linked to nocturia in men

Research from South Korea indicates that low testosterone levels are associated with nocturia in men, independent of both age and prostate volume.

24 Dec 2013

Stomach circadian clock limits food intake to specific times of day

University of Adelaide researchers have discovered the first evidence that the nerves in the stomach act as a circadian clock, limiting food intake to specific times of the day.

5 Dec 2013

Study investigates connections between sleep problems and neurodegenerative conditions

A new discovery may help explain the surprisingly strong connections between sleep problems and neurodegenerative conditions such as Alzheimer's disease.

26 Nov 2013

FDA Advisory Committee votes in favor of Vanda's tasimelteon NDA for Non-24-Hour Disorder

Vanda Pharmaceuticals Inc. announced today that the U.S. Food and Drug Administration's Peripheral and Central Nervous System Drugs Advisory Committee voted overwhelmingly to recommend the approval of Vanda's New Drug Application for tasimelteon, proposed tradename HETLIOZ™, for the treatment of Non-24-Hour Disorder (Non-24) in the totally blind.

15 Nov 2013

Internal body clock may contribute to morning peak in heart attacks and ischemic strokes

Cardiovascular disease is the number one cause of death in both men and women, and most adverse cardiovascular events tend to happen in the morning. In new findings published in the November issue of Blood, researchers from Brigham and Women's Hospital (BWH) and Oregon Health & Science University have discovered that the internal body clock may contribute to the morning peak in heart attacks and ischemic strokes.

13 Nov 2013

School-year bedtimes impact teens’ academic, social and emotional development

Teenagers who go to bed late during the school year are more prone to academic and emotional difficulties in the long run, compared to their earlier-to-bed counterparts, according to a new study from the University of California, Berkeley.

11 Nov 2013

One in six fatal traffic accidents results from drowsy driving, show reports

Many of us make light of that relatively short drive home. But getting behind the wheel when you're sleepy can cost lives and lead to imprisonment and a hefty fine.

29 Oct 2013

Multifactorial approach needed for early bipolar detection

At-risk states for bipolar disorder require a multifaceted approach to be identified and appropriately treated, according to preliminary results from the Dresden High-Risk Project.

24 Oct 2013

Understanding genetic, physiological basis for metabolic diseases related to circadian function

A new study by a team of University of Notre Dame researchers, which appears in the Sept. 2 edition of the journal PLoS ONE, is a significant step in understanding the molecular genetic and physiological basis for a spectrum of metabolic diseases related to circadian function.

24 Sep 2013

Researchers develop new variety of corked microbottle for drugs

Sustained-release formulations that release drugs over longer periods of time are not the final step in the evolution of “intelligent” drug delivery systems. Modern pharmaceuticals are being designed to be released only in a specific, diseased organ; on cues from our circadian rhythm; or under specific physiological conditions.

17 Sep 2013

Insomnia poses hypertension risk

Insomnia may be associated with an increased risk for hypertension, research from China suggests.

16 Sep 2013

Research offers focused explanation for cardiac arrest predilection for morning hours

Evidence from people with heart disease strongly supports the existence of the molecular link first discovered in laboratory mice between the body's natural circadian rhythms and cardiac arrest or sudden cardiac death (SCD) - the No. 1 cause of death in heart attacks, a scientist said here today.

10 Sep 2013

New compound offers way to treat migraine and other disorders of central nervous system

For many migraine sufferers, bright lights are a surefire way to exacerbate their headaches. And for some night-shift workers, just a stroll through a brightly lit parking lot during the morning commute home can be enough to throw off their body's daily rhythms and make daytime sleep nearly impossible. But a new molecule that selectively blocks specialized light-sensitive receptors in the eyes could help both these groups of people, without affecting normal vision.

28 Aug 2013

High-calorie breakfast protects against diabetes, hypertension and cardiovascular problems

Whether you hope to lose weight or just stay healthy, what you eat is a crucial factor. The right nutrients can not only trim your waistline, but also provide energy, improve your mood, and stave off disease. Now a Tel Aviv University researcher has found that it's not just what you eat - but when.

6 Aug 2013

Working shift patterns associated with increased risk of subfertility and menstrual disruption

Shift work, which encourages sleep deprivation and patterns of activity outside the circadian rhythm, has been associated with a greater risk of ill health and loss of well-being in some (but not all) studies.(1) However, little is known about the effects of shift work on reproductive health and fertility.

9 Jul 2013

Study reveals circadian disruption is a risk factor in alcoholic liver disease

Thirty percent of severe alcoholics develop liver disease, but scientists have not been able to explain why only a subset is at risk. A research team from Northwestern University and Rush University Medical Center now has a possible explanation: disrupted sleep and circadian rhythms can push those vulnerable over the edge to disease.

2 Jul 2013

Vanda presents additional data from tasimelteon Phase III studies at ENDO 2013

Vanda Pharmaceuticals Inc. presented additional data today at ENDO 2013, the Endocrine Society's 95th Annual Meeting, demonstrating that tasimelteon can entrain (synchronize) both melatonin and cortisol rhythms.

18 Jun 2013

Circadian Rhythm News and Research

Latest Circadian Rhythm News and Research

Irregular sleep timing disrupts daily rhythms of our genes

Higher levels of melatonin may lower risk for developing advanced prostate cancer

Scientists develop strategies focused on diet to treat patients suffering from circadian dysfunctions

Low testosterone levels linked to nocturia in men

Stomach circadian clock limits food intake to specific times of day

Study investigates connections between sleep problems and neurodegenerative conditions

FDA Advisory Committee votes in favor of Vanda's tasimelteon NDA for Non-24-Hour Disorder

Internal body clock may contribute to morning peak in heart attacks and ischemic strokes

School-year bedtimes impact teens’ academic, social and emotional development

One in six fatal traffic accidents results from drowsy driving, show reports

Multifactorial approach needed for early bipolar detection

Understanding genetic, physiological basis for metabolic diseases related to circadian function

Researchers develop new variety of corked microbottle for drugs

Insomnia poses hypertension risk

Research offers focused explanation for cardiac arrest predilection for morning hours

New compound offers way to treat migraine and other disorders of central nervous system

High-calorie breakfast protects against diabetes, hypertension and cardiovascular problems

Working shift patterns associated with increased risk of subfertility and menstrual disruption

Study reveals circadian disruption is a risk factor in alcoholic liver disease

Vanda presents additional data from tasimelteon Phase III studies at ENDO 2013

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Circadian Rhythm News and Research

Latest Circadian Rhythm News and Research

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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