Cirrhosis News and Research

Latest Cirrhosis News and Research

Researchers uncover new genetic link to non-alcoholic steatohepatitis

Non-alcoholic fatty liver disease (NAFLD) is the accumulation of fat in the liver unrelated to alcohol abuse or other liver diseases. It is often associated with obesity and diabetes and is considered a manifestation of metabolic syndrome.

10 Nov 2021

SBIR grant awarded to develop treatment for alcoholic liver disease-associated hepatorenal syndrome

The Institute of Human Virology (IHV) at the University of Maryland School of Medicine and MitoPower LLC were awarded an SBIR (Small Business Innovation Research) grant of up to $6.5 million over five years from the National Institutes of Health's National Institute on Alcohol Abuse and Alcoholism.

9 Nov 2021

Pathway preferential estrogens may be a safer alternative to hormone replacement therapy, study shows

Postmenopausal women have increased risk of non-alcoholic fatty liver disease due to loss of estrogen from metabolic changes. A high-fat diet further exacerbates the disease, which can progress to cirrhosis and liver failure.

29 Oct 2021

Study focuses on the high hepatitis C rates in pregnant people

Hepatitis C virus (HCV) infection can lead to long-term health problems including liver damage, liver failure, cirrhosis, liver cancer and even death. These outcomes are especially dangerous for pregnant people and their babies.

29 Oct 2021

HCV treatment decreases protein activity levels involved in liver cirrhosis, research shows

Researchers at the Medical University of South Carolina report in the Journal of Viral Hepatitis that the activity levels of the proteins involved in liver scarring, or cirrhosis, begin to decrease immediately after treatment for the hepatitis C virus (HCV), suggesting the possibility of early healing.

26 Oct 2021

Researchers develop genetic risk score to predict development of alcohol-induced cirrhosis

An international research group led by the Centenary Institute has developed a world first genetic risk score (GRS) test able to identify patients at high-risk of developing alcohol-related cirrhosis.

26 Oct 2021

UQ start-up secures $1.3 million seed investment to develop new treatment for liver disease

A University of Queensland start-up company, developing a potential new treatment for obesity-related liver disease, has secured a seed investment of $1.3 million from IP Group, a UK-based intellectual property business.

19 Oct 2021

RUDN study reveals macrophage dynamics in the regenerating liver after resection

RUDN University discovered the features of liver macrophages activation during its regeneration. In future, it can be used to develop new treatment methods for liver cirrhosis. The results are published in the Biomedicine.

15 Oct 2021

Study identifies DNA mutations linking liver disease with obesity and diabetes

For the first time, DNA mutations in liver cells have been identified that impact metabolism and insulin sensitivity in patients with liver disease.

13 Oct 2021

Exosomal and non-exosomal miRNAs may serve as biomarkers for HCV-related cirrhosis, liver cancer

Oncotarget published "Exosomal and non-exosomal miRNA expression levels in patients with HCV-related cirrhosis and liver cancer" which reported that patients with HCV-related cirrhosis are at risk for liver cancer development.

11 Oct 2021

Primary sclerosing cholangitis: Therapy with synthetic bile acid acts directly on the immune system

Primary Sclerosing Cholangitis (PSC) is a rare, chronic inflammatory disease of the bile ducts and is difficult to treat. Studies conducted by the Division of Gastroenterology and Hepatology at MedUni Wien under the guidance of Michael Trauner (Department of Internal Medicine III) were able to show positive effects from the administration of synthetically produced bile acids and bile acid receptor agonists.

28 Sep 2021

Researchers provide structural insights into HCV receptor binding and entry

In a new paper published in Nature, scientists from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, describe the structure of a key protein on the surface of the hepatitis C virus (HCV) and how it interacts with its receptor found on some human cells.

21 Sep 2021

Differences in DNA methylation could accurately predict progression of liver disease

Findings of a national study led by the Translational Genomics Research Institute, an affiliate of City of Hope, identify potential biomarkers that might eventually be used to diagnose progressive stages of liver disease.

20 Sep 2021

New online tool to predict mortality risk for patients with acute-on-chronic liver failure

For patients with chronic liver disease, the onset of acute-on-chronic liver failure (ACLF) instantly alters the transplant question from 'if' to 'when'. 60 to 70% of patients with ACLF die within 3 months due to poor liver function and multiple organ failure.

13 Sep 2021

Research: Only 26% of areas in the UK have an effective pathway in place for early liver disease detection

New research published today in a peer review journal shows only 26% of areas in the UK have an effective pathway in place for the early detection of liver disease.

4 Aug 2021

Children of obese mothers at increased risk of fatty liver disease

Children and young people whose mothers had a BMI greater than 30 during early pregnancy are at an increased risk of fatty liver disease.

19 Jul 2021

Chemical modification in RNA molecules may offer protection against liver disease

A chemical modification that occurs in some RNA molecules as they carry genetic instructions from DNA to cells' protein-making machinery may offer protection against non-alcoholic fatty liver, a condition that results from a build-up of fat in the liver and can lead to advanced liver disease, according to a new study by UCLA researchers.

19 Jul 2021

COVID-19 vaccine offers lesser, delayed protection against infection in people with cirrhosis

A study shows for the first time that people with cirrhosis who receive mRNA COVID-19 vaccination gain important protection against more serious outcomes like hospitalization and death. At the same time, however, the vaccines offer less protection against SARS-CoV-2 infection and take longer to take effect in this population.

14 Jul 2021

New study finds an association between alcohol use and higher risk of several cancers

A new study from the World Health Organization's International Agency for Research on Cancer (IARC), published in the journal Lancet Oncology, has found an association between alcohol and a substantially higher risk of several forms of cancer, including breast, colon, and oral cancers.

14 Jul 2021

Study reveals how non-alcoholic fatty liver disease can develop into a life-threatening complication

Researchers revealed how non-alcoholic fatty liver disease can develop into a life-threatening complication.

13 Jul 2021

Cirrhosis News and Research

Latest Cirrhosis News and Research

Researchers uncover new genetic link to non-alcoholic steatohepatitis

SBIR grant awarded to develop treatment for alcoholic liver disease-associated hepatorenal syndrome

Pathway preferential estrogens may be a safer alternative to hormone replacement therapy, study shows

Study focuses on the high hepatitis C rates in pregnant people

HCV treatment decreases protein activity levels involved in liver cirrhosis, research shows

Researchers develop genetic risk score to predict development of alcohol-induced cirrhosis

UQ start-up secures $1.3 million seed investment to develop new treatment for liver disease

RUDN study reveals macrophage dynamics in the regenerating liver after resection

Study identifies DNA mutations linking liver disease with obesity and diabetes

Exosomal and non-exosomal miRNAs may serve as biomarkers for HCV-related cirrhosis, liver cancer

Primary sclerosing cholangitis: Therapy with synthetic bile acid acts directly on the immune system

Researchers provide structural insights into HCV receptor binding and entry

Differences in DNA methylation could accurately predict progression of liver disease

New online tool to predict mortality risk for patients with acute-on-chronic liver failure

Research: Only 26% of areas in the UK have an effective pathway in place for early liver disease detection

Children of obese mothers at increased risk of fatty liver disease

Chemical modification in RNA molecules may offer protection against liver disease

COVID-19 vaccine offers lesser, delayed protection against infection in people with cirrhosis

New study finds an association between alcohol use and higher risk of several cancers

Study reveals how non-alcoholic fatty liver disease can develop into a life-threatening complication

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Cirrhosis News and Research

Latest Cirrhosis News and Research

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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