Cirrhosis

Cirrhosis is a condition in which the liver slowly deteriorates and malfunctions due to chronic injury. Scar tissue replaces healthy liver tissue, partially blocking the flow of blood through the liver.

What is Cirrhosis?

Cirrhosis is a severe form of liver disease wherein normal liver tissue is replaced by scar tissue (fibrous tissue).

Managing and Treating Cirrhosis

What Causes Cirrhosis?

Liver Disease Symptoms

Study links gut dysbiosis with severe steatosis in MASLD

A new study in eGastroenterology links gut dysbiosis with severe steatosis in metabolic dysfunction–associated steatotic liver disease (MASLD).

15 Oct 2025

Study reports the world's first genetically engineered pig-to-human liver xenotransplantation

An important new study in the Journal of Hepatology, published by Elsevier, reports the world's first auxiliary liver xenotransplant from a genetically engineered pig to a living human recipient.

9 Oct 2025

Khat use linked to autoimmune hepatitis in young men

Khat (Catha edulis), a plant chewed for its stimulant effects by millions in East Africa and the Arabian Peninsula, is increasingly recognized for its hepatotoxic potential.

30 Sep 2025

Categorizing the risk factors for portal vein thrombosis in liver cirrhosis

Portal vein thrombosis (PVT) is a critical complication in liver cirrhosis (LC), significantly worsening portal hypertension and accelerating the progression to decompensation.

30 Sep 2025

Simple blood analysis can predict the risk of developing severe liver disease

A new study from Karolinska Institutet, published in the scientific journal The BMJ, shows how a simple blood analysis can predict the risk of developing severe liver disease.

29 Sep 2025

In hepatitis B vaccine debate, CDC panel sidesteps key exposure risk

The Trump administration is continuing its push to revise federal guidelines to delay the hepatitis B vaccine newborn dose for most children.

29 Sep 2025

Targeting TGF-β signaling as a strategy to treat liver fibrosis

Liver fibrosis, a pathological scarring process resulting from chronic liver injury, represents a significant global health burden due to its potential progression to cirrhosis and hepatocellular carcinoma.

25 Sep 2025

Alcohol-related mortality in the US surged 89% since 1999

A national study reveals a sharp rise in alcohol-induced deaths during COVID-19, with women and Native communities facing the greatest impact.

23 Sep 2025

Coffee protects the liver by blocking inflammation and scarring, review finds

A new review in Biochemical Pharmacology synthesizes decades of research showing consistent links between regular coffee consumption and reduced risk of liver disease, including cirrhosis and liver cancer. Coffee’s bioactive compounds act on antioxidant, anti-inflammatory, antifibrotic, and metabolic pathways to slow liver damage progression.

21 Sep 2025

RFK Jr.’s vaccine panel expected to recommend delaying hepatitis B shot for children

A key federal vaccine advisory panel whose members were recently replaced by Health and Human Services Secretary Robert F. Kennedy Jr. is expected to vote to recommend delaying until age 4 the hepatitis B vaccine that's currently given to newborns, according to two former senior Centers for Disease Control and Prevention officials.

16 Sep 2025

Postpartum mothers more likely to be cured of hepatitis C with bedside treatment

Hepatitis C, a bloodborne virus that damages the liver, can cause cirrhosis, liver cancer, liver failure and death if left untreated.

11 Sep 2025

Shared gene signatures reveal metabolic dysfunction in liver cirrhosis and acute-on-chronic liver failure

Chronic liver cirrhosis (LC) and acute-on-chronic liver failure (ACLF) are interconnected hepatic disorders associated with substantial morbidity and mortality.

27 Aug 2025

CHI3L1 emerges as a powerful biomarker for liver disease diagnosis and management

The identification of Chitinase-3-like protein 1 (CHI3L1) as a crucial biomarker in liver disease is revolutionizing how clinicians approach the diagnosis, monitoring, and treatment of various liver conditions.

22 Aug 2025

Targeting the adrenomedullin pathway may be a potential therapy for liver failure

Liver failure syndromes are characterized by a dysregulated immune response leading to immune paralysis. Adrenomedullin (ADM) is a potent vasodilator and immunoregulator.

18 Aug 2025

Fucosylation emerges as a key player in digestive inflammatory diseases and cancers

Fucosylation, a crucial post-translational modification, has emerged as a significant factor influencing digestive inflammatory diseases and cancers.

18 Aug 2025

Natural gut molecule reverses liver damage and repairs gut lining

UC Davis Health researchers have discovered that a natural molecule made by gut bacteria can reverse liver damage and repair the gut lining after aflatoxin exposure.

12 Aug 2025

Updated multidisciplinary European guidelines redefine MASLD diagnosis and treatment

The 2024 European clinical practice guidelines introduce a pivotal terminology shift, replacing NAFLD (non-alcoholic fatty liver disease) with MASLD (metabolic dysfunction-associated steatotic liver disease) and NASH with MASH (metabolic dysfunction-associated steatohepatitis).

7 Aug 2025

Scarred liver tissue creates fertile ground for cancer development

Over 80% of hepatocellular carcinoma (HCC) – the third-leading cause of cancer deaths globally – emerges from advanced liver fibrosis or cirrhosis. A comprehensive review in Hepatology International synthesizes decades of research to reveal how scarred liver tissue becomes a breeding ground for cancer.

31 Jul 2025

WHO urges urgent action to eliminate hepatitis and reduce liver cancer deaths

As we mark World Hepatitis Day, WHO calls on governments and partners to urgently accelerate efforts to eliminate viral hepatitis as a public health threat and reduce liver cancer deaths.

29 Jul 2025

Study finds significant associations between sleep traits and 172 diseases

A groundbreaking international study, recently published in Health Data Science, analyzed objective sleep data from 88,461 adults in the UK Biobank and found significant associations between sleep traits and 172 diseases.

28 Jul 2025

Cirrhosis

Overview

Managing and Treating Cirrhosis

What Causes Cirrhosis?

Liver Disease Symptoms

Latest Cirrhosis News and Research

Study links gut dysbiosis with severe steatosis in MASLD

Study reports the world's first genetically engineered pig-to-human liver xenotransplantation

Khat use linked to autoimmune hepatitis in young men

Categorizing the risk factors for portal vein thrombosis in liver cirrhosis

Simple blood analysis can predict the risk of developing severe liver disease

In hepatitis B vaccine debate, CDC panel sidesteps key exposure risk

Targeting TGF-β signaling as a strategy to treat liver fibrosis

Alcohol-related mortality in the US surged 89% since 1999

Coffee protects the liver by blocking inflammation and scarring, review finds

RFK Jr.’s vaccine panel expected to recommend delaying hepatitis B shot for children

Postpartum mothers more likely to be cured of hepatitis C with bedside treatment

Shared gene signatures reveal metabolic dysfunction in liver cirrhosis and acute-on-chronic liver failure

CHI3L1 emerges as a powerful biomarker for liver disease diagnosis and management

Targeting the adrenomedullin pathway may be a potential therapy for liver failure

Fucosylation emerges as a key player in digestive inflammatory diseases and cancers

Natural gut molecule reverses liver damage and repairs gut lining

Updated multidisciplinary European guidelines redefine MASLD diagnosis and treatment

Scarred liver tissue creates fertile ground for cancer development

WHO urges urgent action to eliminate hepatitis and reduce liver cancer deaths

Study finds significant associations between sleep traits and 172 diseases

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

Empowering genomics research with cloud-based innovation

Cirrhosis

Overview

Latest Cirrhosis News and Research

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

Empowering genomics research with cloud-based innovation

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