Cirrhosis

Cirrhosis is a condition in which the liver slowly deteriorates and malfunctions due to chronic injury. Scar tissue replaces healthy liver tissue, partially blocking the flow of blood through the liver.

What is Cirrhosis?

Cirrhosis is a severe form of liver disease wherein normal liver tissue is replaced by scar tissue (fibrous tissue).

What Causes Cirrhosis?

Managing and Treating Cirrhosis

Liver Disease Symptoms

Liver cancer cells cause stromal cells to secrete protein that enhances tumor growth

Hepatocellular carcinoma (HCC), frequently seen in patients with liver cirrhosis caused by alcohol abuse or chronic viral hepatitis, is the most common form of liver cancer worldwide.

6 Jan 2021

Study: Frailty is a risk factor among women waiting for liver transplants

Women awaiting liver transplants in the United States are known to be about one-third more likely than men to become too ill to undergo surgery or die before receiving a liver.

4 Jan 2021

Beta-blockers show anti-inflammatory effects in cirrhosis

Approximately 170,000 people die every year in Europe from the direct consequences of advanced chronic liver disease (cirrhosis).

10 Dec 2020

New article highlights health disparities, social determinants of health

The December issue of The American Journal of Gastroenterology is now available and features new clinical research across a wide range of gastroenterology and hepatology topics, including health disparities, colorectal cancer, cirrhosis, pediatric gastroenterology, the environmental impact of endoscopy, and more.

7 Dec 2020

Non-invasive MRI technology helps improve surgical decision-making in liver cancer care

A newly published study on patients with primary and secondary liver cancer shows how Perspectum’s non-invasive MRI technology can help predict those at increased risk of poor surgical outcomes, potentially reducing healthcare costs by shortening length of hospital stay.

4 Dec 2020

NMR-based diagnostic tool could be used to detect fatty liver disease or liver fibrosis

About 25 percent of the U.S. population suffers from fatty liver disease, a condition that can lead to fibrosis of the liver and, eventually, liver failure.

2 Dec 2020

Systemic inflammation increases over various stages of liver cirrhosis, shows study

Patients with liver cirrhosis display a wide range of clinical symptoms. A prospective study conducted by MedUni Vienna has now shown that blood levels of biomarkers for systemic inflammation increase over the various stages of the disease and can predict the development of complications, even in previously asymptomatic patients.

30 Nov 2020

Antimicrobial found in soaps worsens fatty liver disease in mice

University of California San Diego School of Medicine researchers found evidence that triclosan -- an antimicrobial found in many soaps and other household items -- worsens fatty liver disease in mice fed a high-fat diet.

23 Nov 2020

Scientists find significant differences in liver-related mortality rates in the U.S

When they set out to study local levels of death from liver diseases in the U.S., University of Miami Miller School of Medicine and Emory researchers found significant differences in death rates even within the same state, according to a recently published study in Gastroenterology.

19 Nov 2020

LOX plays a number of key roles in promoting skin and organ fibrosis in scleroderma

A team of researchers at the Medical University of South Carolina (MUSC) has found that the molecule lysyl oxidase (LOX) plays a number of important roles in promoting skin and organ fibrosis in scleroderma, a connective tissue disorder.

17 Nov 2020

Study could pave the way for potential urine test to diagnose liver fibrosis

Fifty fragments of proteins, termed peptides, have been identified in the urine of liver fibrosis patients in a new study that could pave the way for a potential diagnostic urine test for the condition if further validated.

16 Nov 2020

Study reveals new source of abnormal lymphatic flow that may account for plastic bronchitis

Interventional radiologists with Nemours Children's Health System have identified a new source of abnormal lymphatic flow between the liver and the lungs that may be responsible for some cases of plastic bronchitis.

11 Nov 2020

A substantial minority of middle-aged adults have liver fibrosis

A substantial minority of participants from the Framingham Heart Study, (nearly nine percent), had potentially clinically significant liver fibrosis (scarring). This the first study of this size and scale done in the United States.

9 Nov 2020

SARS-CoV-2 viral antigens found in non-pulmonary tissues in recovering patients

A team of researchers in Singapore, led by Dr. Joe Yeong, and Prof. Tony Kiat Hon Lim, have reported the presence of residual SARS-CoV-2 ribonucleic acid (RNA) – the virus' genetic material – in stool samples and gastrointestinal tissues from patients recovering from the coronavirus disease 2019 (COVID-19).

8 Nov 2020

Dietary supplement helps prevent fatty liver disease in rats

A recent study by researchers at the University of Jyväskylä was successful in partially preventing fatty liver disease in rats.

4 Nov 2020

Dietary restriction effective in reducing the odds of developing liver cancer from fatty liver

Liver cancer from too much fat accumulation in the liver has been increasing in many countries including Japan.

29 Oct 2020

Researchers apply a novel technique to improve understanding of liver disease, immune activation

Human cells are encased by a membrane coated with diverse sugar molecules known as glycans. These glycans play many roles in health and disease, making them important to understand.

20 Oct 2020

Serum metabolite profile can help identify individuals at risk of alcohol-related disease

A new study from the University of Eastern Finland is the first in the world to show that the serum metabolite profile can be used to identify individuals likely at risk of developing an alcohol-related disease in the future.

19 Oct 2020

Start-up receives NIH grant to accelerate development of contrast agent to detect liver fibrosis

Inlighta Biosciences, LLC, a start-up company led by Jenny Yang, Regents' Professor of Chemistry at Georgia State University, has been awarded a National Institute of Health grant to accelerate development of a magnetic resonance imaging contrast agent to detect liver fibrosis, formation of scar tissue in the liver caused by alcoholic and non-alcoholic fatty liver disease.

15 Oct 2020

Even mild fatty liver disease associated with higher risk of all-cause mortality

Non-alcoholic fatty liver disease, NAFLD, affects nearly one in four adults in Europe and the U.S. Earlier research has demonstrated an increased risk of death in patients with NAFLD and advanced fibrosis or cirrhosis.

12 Oct 2020

Cirrhosis

Overview

What Causes Cirrhosis?

Managing and Treating Cirrhosis

Liver Disease Symptoms

Latest Cirrhosis News and Research

Liver cancer cells cause stromal cells to secrete protein that enhances tumor growth

Study: Frailty is a risk factor among women waiting for liver transplants

Beta-blockers show anti-inflammatory effects in cirrhosis

New article highlights health disparities, social determinants of health

Non-invasive MRI technology helps improve surgical decision-making in liver cancer care

NMR-based diagnostic tool could be used to detect fatty liver disease or liver fibrosis

Systemic inflammation increases over various stages of liver cirrhosis, shows study

Antimicrobial found in soaps worsens fatty liver disease in mice

Scientists find significant differences in liver-related mortality rates in the U.S

LOX plays a number of key roles in promoting skin and organ fibrosis in scleroderma

Study could pave the way for potential urine test to diagnose liver fibrosis

Study reveals new source of abnormal lymphatic flow that may account for plastic bronchitis

A substantial minority of middle-aged adults have liver fibrosis

SARS-CoV-2 viral antigens found in non-pulmonary tissues in recovering patients

Dietary supplement helps prevent fatty liver disease in rats

Dietary restriction effective in reducing the odds of developing liver cancer from fatty liver

Researchers apply a novel technique to improve understanding of liver disease, immune activation

Serum metabolite profile can help identify individuals at risk of alcohol-related disease

Start-up receives NIH grant to accelerate development of contrast agent to detect liver fibrosis

Even mild fatty liver disease associated with higher risk of all-cause mortality

Treating post-infectious smell loss in COVID-19 patients

A paper-based sensor for detecting COVID-19

Cadmium linked to more severe flu and pneumonia infections

Cirrhosis

Overview

Latest Cirrhosis News and Research

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