Cirrhosis News and Research

Latest Cirrhosis News and Research

Study identifies factors tied to greater risk of advanced liver disease in cystic fibrosis patients

Children's Hospital Colorado pediatric gastroenterologist, Michael Narkewicz, MD, recently shared results of the Prospective Study of Ultrasound to Predict Hepatic Cirrhosis in Cystic Fibrosis, which sought to determine if liver ultrasounds could identify children and adolescents with cystic fibrosis who are at greater risk of developing advanced liver disease.

13 Nov 2018

Study offers hope of early detection, treatment of liver cancer

Liver cancer is the second leading cause of cancer-related mortality worldwide, claiming 700,000 lives each year. Most cases are discovered too late for a cure -- but now a study offers hope of early detection, and targets for new treatments.

31 Oct 2018

Novartis enters into clinical development agreement with Pfizer to improve treatment of NASH

Novartis announced today that it has entered into a clinical development agreement with Pfizer which will include a study combining tropifexor and one or more Pfizer compounds for the treatment of NASH, including an Acetyl CoA-Carboxylase (ACC) Inhibitor (PF-05221304, a Diacylglycerol O-Acyltransferase 2 (DGAT2) Inhibitor (PF-06865571, and a Ketohexokinase (KHK) Inhibitor (PF-06835919).

29 Oct 2018

Researchers identify new potential target to inhibit progression of liver disease

Naglaa Shoukry, Ph. D., and her team have made a significant breakthrough in their research aiming to limit the progression of liver disease.

26 Oct 2018

One-time universal screening recommended to tackle increase in hepatitis C

Physicians are encountering a growing number of younger patients who are testing positive for hepatitis C virus fueled largely by the opioid crisis impacting communities around the country.

17 Oct 2018

King's College researchers awarded £2.3 million for new trial to treat liver disease

Dr Mark McPhail from the Department of Inflammation Biology, School of Immunology & Microbial Sciences and Dr Vishal Patel from the Institute of Liver Studies at King's College Hospital have been awarded £2.3 million by the National Institute of Health Research Health Technology Assessment to lead a new UK wide multi-centre trial to treat liver disease.

9 Oct 2018

Alnylam submits CTA application to MHRA to initiate Phase 1/2 study of ALN-AAT02

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today that it has submitted a Clinical Trial Authorization application to the Medicines and Healthcare products Regulatory Agency to initiate a Phase 1/2 study of ALN-AAT02, an investigational RNAi therapeutic targeting alpha-1 antitrypsin for the treatment of AAT deficiency-associated liver disease.

3 Oct 2018

New studies examine links between fatty liver disease and mitochondrial dysfunction

Researchers at Northeast Ohio Medical University studied the lifespan of mitochondrial proteins in a mouse model of fatty liver disease. Comparing the amount of protein between healthy mice and a mouse model of nonalcoholic fatty liver disease gave them an estimate of each protein's half-life.

17 Sep 2018

Shionogi launches Mulpleta in the U.S for safe, effective treatment of thrombocytopenia

Shionogi & Co., Ltd. announced today that Mulpleta (lusutrombopag), a once-daily, orally administered, small molecule thrombopoietin (TPO) receptor agonist for the treatment of thrombocytopenia in adult patients with chronic liver disease (CLD) who are scheduled to undergo a procedure, is now available throughout the United States.

30 Aug 2018

Routine oral care to treat gum disease may improve cognitive function in cirrhosis patients

Routine oral care to treat gum disease may play a role in reducing inflammation and toxins in the blood and improving cognitive function in people with liver cirrhosis.

29 Aug 2018

New lung tissue-on-a-chip system offers rapid testing of potential anti-fibrotic treatments

Pulmonary fibrosis is one of the most common and serious types of lung disease. Now NIBIB-funded researchers have developed an in vitro lung tissue-on-a-chip system that mimics lung fibrosis, offering rapid testing of potential new anti-fibrotic treatments.

28 Aug 2018

Newly discovered target may prevent progression of liver injury to cancer

Problems like obesity and alcoholism appear to chronically trigger in the liver a receptor known to amplify inflammation in response to invaders like bacteria, scientists report.

27 Aug 2018

Surgeons test new device that keeps the liver warm and circulates blood during transport

Since the first liver transplant in 1963, donated livers have been immersed in an icy cold fluid in a cold storage system for transport, similar in principle to ice chests used for picnics and trips to the beach.

25 Aug 2018

Researchers win multi-million Euro award to conduct research into liver disease

A team of researchers from the School of Immunology and Microbial Sciences and the Dental Institute has secured a multi-million Euro award to conduct research into liver disease.

16 Aug 2018

FDA approves first vaginal ring contraceptive that can be used for one year

The U.S. Food and Drug Administration today approved Annovera (segesterone acetate and ethinyl estradiol vaginal system), which is a combined hormonal contraceptive for women of reproductive age used to prevent pregnancy and is the first vaginal ring contraceptive that can be used for an entire year.

10 Aug 2018

FIND and genedrive announce study agreement to evaluate HCV ID Kit

genedrive plc, a near patient molecular diagnostics company, and the Foundation for Innovation of New Diagnostics (FIND), announced today a study agreement for the performance evaluation of genedrive plc’s hepatitis C virus (HCV) Genedrive HCV ID Kit.

10 Aug 2018

Scientists identify two potential new drug targets for treatment of HIV

Johns Hopkins scientists report they have identified two potential new drug targets for the treatment of HIV. The finding is from results of a small, preliminary study of 19 people infected with both HIV - the virus that causes AIDS - and the hepatitis C virus.

7 Aug 2018

Genetic factors may play a role in progression of liver injury in Caucasians with hepatitis B infection

A new study has shown that genetic variation may increase the risk of severe liver damage in Caucasians with chronic hepatitis B infection.

27 Jul 2018

Researchers emphasize need for baby boomers to get tested for hepatitis C

According to the Centers for Disease Control and Prevention, 300 million people across the globe are unaware they're living with viral hepatitis. In fact, baby boomers - those born between 1945-1965 - are five times more likely to have hepatitis C, one of the many different strains of this viral infection.

27 Jul 2018

Bile acids from the gut may offer new treatment for cocaine abuse

Bile acids that aid fat digestion are also found to reduce the rewarding properties of cocaine use, according to a study publishing on July 26 in the open-access journal PLOS Biology by India Reddy, Nicholas Smith, and Robb Flynn of Vanderbilt University, Aurelio Galli of the University of Alabama at Birmingham, and colleagues.

27 Jul 2018

Cirrhosis News and Research

Latest Cirrhosis News and Research

Study identifies factors tied to greater risk of advanced liver disease in cystic fibrosis patients

Study offers hope of early detection, treatment of liver cancer

Novartis enters into clinical development agreement with Pfizer to improve treatment of NASH

Researchers identify new potential target to inhibit progression of liver disease

One-time universal screening recommended to tackle increase in hepatitis C

King's College researchers awarded £2.3 million for new trial to treat liver disease

Alnylam submits CTA application to MHRA to initiate Phase 1/2 study of ALN-AAT02

New studies examine links between fatty liver disease and mitochondrial dysfunction

Shionogi launches Mulpleta in the U.S for safe, effective treatment of thrombocytopenia

Routine oral care to treat gum disease may improve cognitive function in cirrhosis patients

New lung tissue-on-a-chip system offers rapid testing of potential anti-fibrotic treatments

Newly discovered target may prevent progression of liver injury to cancer

Surgeons test new device that keeps the liver warm and circulates blood during transport

Researchers win multi-million Euro award to conduct research into liver disease

FDA approves first vaginal ring contraceptive that can be used for one year

FIND and genedrive announce study agreement to evaluate HCV ID Kit

Scientists identify two potential new drug targets for treatment of HIV

Genetic factors may play a role in progression of liver injury in Caucasians with hepatitis B infection

Researchers emphasize need for baby boomers to get tested for hepatitis C

Bile acids from the gut may offer new treatment for cocaine abuse

Innovation in neuroscience drug discovery - eBook eBook

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

Cirrhosis News and Research

Latest Cirrhosis News and Research

Innovation in neuroscience drug discovery - eBook eBook

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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