Colorectal Cancer

Colorectal Cancer is cancer that develops in the colon (the longest part of the large intestine) and/or the rectum (the last several inches of the large intestine before the anus). In the United States, it is the fourth most common cancer in men and women. Caught early, it is often curable.

What Causes Colorectal Cancer?

Cancer occurs when a normal cell divides and multiples uncontrollably. Normally cells are regulated in their growth, maturity, division and death by the DNA present in their nucleus. With damage to the DNA the cells may become rogue and multiply uncontrollably to give rise to tumors.

What is Colorectal Cancer?

Colorectal Cancer Diagnosis

Colorectal Cancer Prevention

Colorectal Cancer Management

Colorectal Cancer Prognosis

Colorectal Cancer Symptoms

Colorectal Cancer Pathogenesis

Microbial Dysbiosis and Colorectal Cancer

Colorectal Cancer and Organ Preservation

Latest Colorectal Cancer News and Research

Study defines how the circadian clock influences cell growth, metabolism and tumor progression

In a new University of California, Irvine-led study, researchers define how the circadian clock influences cell growth, metabolism and tumor progression.

11 Aug 2022

Optical coherence tomography combined with machine learning to develop colorectal cancer imaging tool

A research team from the lab of Quing Zhu, the Edwin H. Murty Professor of Engineering in the Department of Biomedical Engineering at the McKelvey School of Engineering at Washington University in St. Louis, has combined optical coherence tomography (OCT) and machine learning to develop a colorectal cancer imaging tool that may one day improve the traditional endoscopy currently used by doctors.

4 Aug 2022

Personal health records may be useful for patient self-management and communication in colorectal cancer networks

JMIR Publications recently published "Uses of Personal Health Records for Communication Among Colorectal Cancer Survivors, Caregivers, and Providers: Interview and Observational Study in a Human-Computer Interaction Laboratory" in JMIR Human Factors which reported that personal health records (PHRs) may be useful for patient self-management and participation in communication with their caregivers and health care providers.

2 Aug 2022

New guidelines for breast cancer screening and diagnosis helps people understand their personal risk

The National Comprehensive Cancer Network has published new NCCN Guidelines for Patients: Breast Cancer Screening and Diagnosis to help people understand their personal risk for breast cancer,

27 Jul 2022

Study clarifies the role of intestinal white blood cells in colorectal cancer

Colorectal tumors are swarming with white blood cells, but whether these cells help or hinder the cancer is hotly debated.

22 Jul 2022

Researchers report genomic profiling from more than 110,000 tumors

Researchers analyzed data from the latest public release of the GENIE project of the American Association for Cancer Research.

19 Jul 2022

Grant funds research that investigates relationships between certain fungi and specific cancers

Dr. Iliyan D. Iliev, an associate professor of immunology and microbiology in the Division of Gastroenterology and Hepatology and a member of the Jill Roberts Institute for Research in Inflammatory Bowel Disease at Weill Cornell Medicine, has been awarded a five-year, $1.25 million CRI Lloyd J. Old STAR (Scientists Taking Risks) Program grant from Cancer Research Institute (CRI).

19 Jul 2022

Bacterial species known for causing diarrheal infections may also drive colorectal cancer

Data collected by researchers at the Johns Hopkins Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy suggest that Clostridioides difficile, or C. diff, a bacterial species well known for causing serious diarrheal infections, may also drive colorectal cancer.

14 Jul 2022

Study identifies a protein that plays key role in protecting the gastrointestinal tract from inflammation

A protein called Zbtb46, expressed by specialized immune cells, has a major role in protecting the gastrointestinal tract from excessive inflammation, according to a study from researchers at Weill Cornell Medicine.

13 Jul 2022

Researchers develop an AI system to classify IBD neoplasia lesions accurately

The incidence of inflammatory bowel disease (IBD)-;an intractable disease characterized by chronic inflammation of the gastrointestinal (GI) tract-;has increased significantly in Japan.

13 Jul 2022

The interplay of family history and genome-wide polygenic risk scores across 24 common diseases

A new study has investigated the interplay of FH and genome-wide PRS

11 Jul 2022

GI cancer survival rates improving among Northern Territorians except for Aboriginal and Torres Strait Islander people

Survival rates for gastrointestinal (GI) cancer among Northern Territorians have improved in the past 30 years but Aboriginal and Torres Strait Islander peoples living in the Territory still have worse survival outcomes, a new analysis has found.

8 Jul 2022

Newly identified gut bacterial strains could pave the way for IBD and colon cancer prevention

Researchers have isolated five strains of gut bacteria that could pave the way for new inflammatory bowel disease treatments and potentially help prevent some forms of bowel cancer.

5 Jul 2022

Scientists use single cell techniques to uncover a central dichotomy for colorectal cancer cells

A team of clinician-scientists and scientists, led by the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore together with collaborators in Europe and South Korea, used single-cell techniques to uncover a central dichotomy for colorectal cancer cells, leading to a proposed update of the classification system for the disease.

1 Jul 2022

Study finds above-average rates of mortality from gastric cancer in South Florida

South Florida counties have above-average rates of mortality from gastric cancer, according to a new study published in the journal Gastroenterology by investigators at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine.

29 Jun 2022

Study discovers microbial link between Western-style diet and colorectal cancer risk

New research builds the case that a Western-style diet -; rich in red and processed meat, sugar and refined grains/carbohydrates -; is tied to higher risk of colorectal cancer through the intestinal microbiota. Investigators from Brigham and Women's Hospital with collaborators looked at data from more than 134,000 participants from two U.S.-wide prospective cohort studies.

27 Jun 2022

Listeria-based booster vaccine strategy offers improved protection against recurrent colorectal cancer

Colorectal, pancreatic, esophageal and stomach cancers-;some of the deadliest kinds of cancer-; have high recurrence rates where the cancer comes back even after successful surgery or radiation treatment.

23 Jun 2022

Researchers identify biomarkers that could be targets for novel drugs to treat glioblastoma

Biomarkers that could be targets for novel drugs to treat glioblastoma brain tumors have been identified by investigators at Georgetown Lombardi Comprehensive Cancer Center, providing hope for a cancer that is highly lethal.

22 Jun 2022

Study: NOSES could achieve good short-term and oncological outcomes for colorectal cancer patients

This study is led by Prof. Xishan Wang (Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College), Prof. Chuangang Fu (Shanghai East Hospital, Tongji University School of Medicine), Dr. Xu Guan (Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College), Dr. Xiyue Hu (Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College) and Prof. Zheng Jiang (Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College), on behalf of China NOSES Alliance.

15 Jun 2022

Understanding how diet and the microbiome impact colorectal cancer rates

While recommended screenings beginning at age 45 have helped decrease colorectal cancer cases in older adults, cancer rates are continuing to increase in younger populations.

14 Jun 2022

Colorectal Cancer

Overview

What is Colorectal Cancer?

Colorectal Cancer Diagnosis

Colorectal Cancer Prevention

Feature Articles

Colorectal Cancer Management

Colorectal Cancer Prognosis

Colorectal Cancer Symptoms

Colorectal Cancer Pathogenesis

Microbial Dysbiosis and Colorectal Cancer

Colorectal Cancer and Organ Preservation

Latest Colorectal Cancer News and Research

Study defines how the circadian clock influences cell growth, metabolism and tumor progression

Optical coherence tomography combined with machine learning to develop colorectal cancer imaging tool

Personal health records may be useful for patient self-management and communication in colorectal cancer networks

New guidelines for breast cancer screening and diagnosis helps people understand their personal risk

Study clarifies the role of intestinal white blood cells in colorectal cancer

Researchers report genomic profiling from more than 110,000 tumors

Grant funds research that investigates relationships between certain fungi and specific cancers

Bacterial species known for causing diarrheal infections may also drive colorectal cancer

Study identifies a protein that plays key role in protecting the gastrointestinal tract from inflammation

Researchers develop an AI system to classify IBD neoplasia lesions accurately

The interplay of family history and genome-wide polygenic risk scores across 24 common diseases

GI cancer survival rates improving among Northern Territorians except for Aboriginal and Torres Strait Islander people

Newly identified gut bacterial strains could pave the way for IBD and colon cancer prevention

Scientists use single cell techniques to uncover a central dichotomy for colorectal cancer cells

Study finds above-average rates of mortality from gastric cancer in South Florida

Study discovers microbial link between Western-style diet and colorectal cancer risk

Listeria-based booster vaccine strategy offers improved protection against recurrent colorectal cancer

Researchers identify biomarkers that could be targets for novel drugs to treat glioblastoma

Study: NOSES could achieve good short-term and oncological outcomes for colorectal cancer patients

Understanding how diet and the microbiome impact colorectal cancer rates

Costly Chemicals; The Health and Economic Impact of 'Forever Chemicals'

Crying out for new disease diagnoses

Understanding the emotions behind memories

Colorectal Cancer

Overview

Feature Articles

Colorectal Cancer Management

Colorectal Cancer Prognosis

Colorectal Cancer Symptoms

Colorectal Cancer Pathogenesis

Microbial Dysbiosis and Colorectal Cancer

Colorectal Cancer and Organ Preservation

Latest Colorectal Cancer News and Research

Costly Chemicals; The Health and Economic Impact of 'Forever Chemicals'

Crying out for new disease diagnoses

Understanding the emotions behind memories

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