Colorectal Cancer

Colorectal Cancer is cancer that develops in the colon (the longest part of the large intestine) and/or the rectum (the last several inches of the large intestine before the anus). In the United States, it is the fourth most common cancer in men and women. Caught early, it is often curable.

Cured Meats, Nitrates, and Cancer Risk: Why Food Source and Processing Matter

From bacon and hot dogs to deli meats, cured meat products contain chemical compounds that increase the risk of cancer.

Colorectal Cancer Management

Colorectal Cancer Prevention

What Causes Colorectal Cancer?

What is Colorectal Cancer?

Colorectal Cancer Prognosis

Colorectal Cancer Symptoms

Colorectal Cancer Diagnosis

Colorectal Cancer and Organ Preservation

Colorectal Cancer Pathogenesis

Microbial Dysbiosis and Colorectal Cancer

Latest Colorectal Cancer News and Research

Laser irradiation boosts antibody-antigen interactions to detect colorectal cancer

Researchers often use antibodies to detect specific molecules or biological markers, as they are remarkably precise at recognizing their targets.

25 Sep 2026

Why are more younger adults in the Eastern Mediterranean facing colorectal cancer?

A 22-country analysis of modeled GLOBOCAN 2022 data found 15,381 early-onset colorectal cancer cases and 6,965 related deaths across the WHO Eastern Mediterranean Region, with substantial differences between countries and comparatively high mortality. Projections suggest that annual case and death counts could rise markedly by 2050, largely due to demographic change, while the findings support screening and detection strategies tailored to local resources and disease burden.

24 Sep 2026

MIT biologists discover cellular pathway that triggers colon cancer spread

Most colon cancer deaths are caused by the spread of tumor cells beyond the colon, usually to the liver. In a new study, MIT biologists identified a cellular pathway necessary for colorectal cancer metastasis.

24 Sep 2026

Cancer incidence rises faster among people with type 2 diabetes

A nationwide study being presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) has found that people with type 2 diabetes (T2D) have a higher risk of developing cancer, with cancer incidence rising more among people with T2D than those without diabetes over the past 25 years, largely driven by obesity-related cancers.

22 Sep 2026

Garvan research reveals hidden inflammation behind high colon cancer risk

New research from the Garvan Institute of Medical Research has revealed for the first time that two closely related bowel diseases, currently treated in the same way, are fundamentally different.

22 Sep 2026

Sugary drinks stood out in this stomach cancer study, but diet drinks did not

In two large US prospective cohorts, consuming more than one sugar-sweetened beverage a day was associated with higher gastric cancer incidence compared with consuming less than one serving a month. Artificially sweetened beverages were not associated with gastric cancer incidence, and the authors called for further studies to confirm the findings and clarify possible biological mechanisms.

21 Sep 2026

Simple fecal test could help detect colorectal and pancreatic cancers

Gastrointestinal and pancreatobiliary cancers can be difficult to detect early, creating a need for practical, noninvasive approaches for early detection and risk assessment.

16 Sep 2026

New AACR report outlines future of cutting-edge cancer research

Today, the American Association for Cancer Research (AACR) released the 16th edition of its annual Cancer Progress Report.

16 Sep 2026

FDA clears trial of dual-targeted CAR T-cell therapy for cancer

The U.S. Food and Drug Administration this week granted permission for investigators at the University of Colorado Anschutz to conduct a clinical trial testing genetically engineered immune cells in adults with advanced colorectal cancer and pediatric patients with solid cancers who have exhausted standard treatment options.

11 Sep 2026

Coffee after colorectal cancer? Decaf and caffeine show different links with mortality

In a prospective analysis of 1,098 people with colorectal cancer, researchers found no significant association between total or caffeinated coffee intake and all-cause or colorectal cancer-specific mortality in the cohort overall. Decaffeinated coffee was associated with lower all-cause mortality, while the highest quartile of caffeine intake was associated with lower all-cause and colorectal cancer-specific mortality, although the observational study cannot establish causation.

10 Sep 2026

New AI tool automates colonoscopy quality assessment at scale

Colonoscopies are one of the most effective ways to prevent colorectal cancer, which is surging among young adults in the U.S. Yet, the quality of each procedure can vary substantially from one physician to another.

8 Sep 2026

Helicobacter pylori exposure linked to one in five cases of bowel cancer

Exposure to the stomach microbe Helicobacter pylori may be associated with more than 1 in 5 cases of bowel cancer worldwide, suggests an exploratory risk attribution study, published in the open access journal eGastroenterology.

8 Sep 2026

Microscopic peptide droplets reduce colorectal tumor growth in mice

Scientists from Nanyang Technological University, Singapore (NTU Singapore) have developed microscopic peptide droplets that deliver large amounts of gene-silencing molecules into cancer and immune cells, reducing the growth of hard-to-treat colorectal tumours by about 67 per cent in mice.

3 Sep 2026

IBD patients with family cancer history more likely to develop colorectal cancer

People with inflammatory bowel disease (IBD) who have several close relatives with colorectal cancer are significantly more likely to develop the disease themselves.

3 Sep 2026

Alcohol-linked cancer deaths doubled over three decades in America

Alcohol-attributable cancer deaths in the U.S. doubled between 1990 and 2023, a new study found. The study also revealed that alcohol-linked cancer deaths are not limited to older adults or liver cancer.

2 Sep 2026

Early-onset bowel cancer shows distinct biological and clinical features

One of Australia's largest real world studies of younger adults with advanced bowel cancer has identified important differences between cancers diagnosed before and after the age of 50, which could help doctors tailor treatments for younger adults more effectively.

1 Sep 2026

Biosimilars reduce financial burden for cancer patients and insurers

Biologic drugs play an important role in treating cancers such as breast cancer and lymphoma, but their high costs can add to the financial burden of cancer care.

27 Aug 2026

New study tracks global colorectal cancer risk across 185 nations

Colorectal cancer has long been recognized as a major global health threat, but its burden is far from evenly distributed. Incidence and mortality rates vary dramatically across countries, and these differences are closely tied to socioeconomic development, dietary transitions, and the adoption of screening programs.

26 Aug 2026

Scientists found a distinct gut microbiome pattern in people with symptomatic diverticular disease

A multicenter Japanese study found that symptomatic uncomplicated diverticular disease (SUDD) was associated with reduced gut microbial diversity, increased abundance of the Ruminococcus gnavus group, and depletion of Coprococcus and other butyrate-producing bacteria. Predictive microbiome analysis also identified enrichment of pathways linked to exopolysaccharide biosynthesis and the cell cycle, although the observational design means these associations cannot establish causality.

25 Aug 2026

New discovery helps identify colorectal cancer patients at risk for metastasis

Researchers from the University of Turku in Finland and Gustave Roussy Institute in France have discovered a molecular mechanism that regulates whether the cells of an aggressive colorectal cancer are conventional or inverted when they spread in the body.

25 Aug 2026