Colorectal Cancer

Colorectal Cancer is cancer that develops in the colon (the longest part of the large intestine) and/or the rectum (the last several inches of the large intestine before the anus). In the United States, it is the fourth most common cancer in men and women. Caught early, it is often curable.

What Causes Colorectal Cancer?

Cancer occurs when a normal cell divides and multiples uncontrollably. Normally cells are regulated in their growth, maturity, division and death by the DNA present in their nucleus. With damage to the DNA the cells may become rogue and multiply uncontrollably to give rise to tumors.

Colorectal Cancer Prognosis

Microbial Dysbiosis and Colorectal Cancer

Colorectal Cancer Management

Colorectal Cancer Pathogenesis

Colorectal Cancer and Organ Preservation

Colorectal Cancer Diagnosis

Colorectal Cancer Prevention

Colorectal Cancer Symptoms

What is Colorectal Cancer?

Latest Colorectal Cancer News and Research

The 15th AACR cancer progress report highlights scientific advances

The American Association for Cancer Research (AACR) released the 15th edition of its annual Cancer Progress Report. A cornerstone of the AACR's educational and advocacy efforts, this comprehensive report provides the latest statistics on cancer incidence, mortality, and survivorship and highlights how federal investments in basic, translational, and clinical cancer research and cancer-related population sciences have led to impressive scientific advances that are improving health and saving lives.

17 Sep 2025

Can high-protein supplements improve cancer recovery?

A systematic review shows high-protein oral nutritional supplements can lower complications and hospital stays in cancer patients, improving recovery outcomes.

16 Sep 2025

Personalized risk information does not increase colorectal cancer screening rates

A new Indiana University School of Medicine clinical trial - the largest of its kind to date - found that providing personalized colorectal cancer risk information to patients and their health care providers did not improve screening rates for the deadly ailment.

16 Sep 2025

Planetary health diet links to longer life and lower emissions

Greater adherence to the Planetary Health Diet was linked to lower all-cause, cancer, and respiratory mortality across large US and UK cohorts, supported by a meta-analysis of 37 studies. Diets higher in PHD foods also had smaller greenhouse gas footprints, reinforcing health and environmental benefits.

9 Sep 2025

High consumption of ultra-processed foods increases a sensitive marker of inflammation

Ultra-processed foods (UPFs) are industrially altered products – like soda, snacks and processed meats – packed with additives and stripped of nutrients.

9 Sep 2025

BioDlink fast-tracks global growth with bevacizumab launch in Colombia and Pakistan

BioDlink announced that its self-developed bevacizumab injection biosimilar has received marketing approval from Colombia’s National Institute for Surveillance of Medicines and Foods (INVIMA) and Pakistan’s Drug Regulatory Authority of Pakistan (DRAP).

From BioDlink 8 Sep 2025

WHO expands essential medicines lists with new cancer and diabetes treatments

Today, the World Health Organization (WHO) has released updated editions of its Model Lists of Essential Medicines (EML) and Essential Medicines for Children (EMLc), adding new treatments for various types of cancer and for diabetes with associated comorbidities such as obesity.

5 Sep 2025

Colorectal cancer identified by its unique microbial fingerprint

Colorectal cancer is unique in having its own microbial 'fingerprint' – according to new research from the University of East Anglia.

3 Sep 2025

Illinois researchers highlight most effective nutritional approaches for GI distress in cancer care

Many modern cancer treatments are highly effective at reducing or eliminating tumors, but they can also cause severe gastrointestinal symptoms that impact patients' quality of life or lead to discontinuation of treatment.

28 Aug 2025

New imaging method detects colorectal cancer using tissue autofluorescence

Colorectal cancer (CRC) is one of the most common and deadly forms of cancer worldwide. A key reason for its high death toll is that it often goes undetected until it reaches an advanced stage.

28 Aug 2025

Gut bacteria provide key to identifying colorectal cancer from stool samples

Colorectal cancer is the second leading cause of cancer death worldwide. If detected early, it can be efficiently treated, but the cost and discomfort of colonoscopies - the main diagnostic method currently in use - often result in delayed diagnosis.

25 Aug 2025

Carriers of colibactin-producing E. coli face threefold increase in colorectal cancer risk

Researchers from Kyoto Prefectural University of Medicine and collaborating Japanese institutions found that patients carrying colibactin-producing Escherichia coli (pks+ E. coli) in their colon polyps were more than three times as likely to have a history of colorectal cancer compared to those without the bacterium.

22 Aug 2025

AI model detects genetic changes in colorectal cancer from tissue images

An international, interdisciplinary research team led by Prof. Jakob N. Kather from the Else Kröner Fresenius Center (EKFZ) for Digital Health at TUD Dresden University of Technology analyzed seven independent patient cohorts from Europe and the USA using their newly developed AI model.

20 Aug 2025

Study finds link between epigenetic aging and colorectal cancer risk in postmenopausal women

A new research paper was published in Volume 17, Issue 7 of Aging (Aging-US) on July 7, 2025, titled "Epigenetic age and accelerated aging phenotypes: a tumor biomarker for predicting colorectal cancer."

19 Aug 2025

Using AI to enhance the design of nanoparticles for RNA therapies

Using artificial intelligence, MIT researchers have come up with a new way to design nanoparticles that can more efficiently deliver RNA vaccines and other types of RNA therapies.

18 Aug 2025

Study finds vegetarians less likely to develop several common and rare cancers

A large North American cohort study found that vegetarian diets were linked to lower risks of several cancers, including colorectal, stomach, breast, prostate, and lymphoproliferative cancers. No evidence suggested that vegetarian eating increased cancer risk for any site.

14 Aug 2025

Microbial DNA signature in the blood differentiates primary liver cancer from metastatic colorectal cancer

Determining whether a cancerous tumor originated in a given location or spread there from another tissue or organ in the body is important when assessing the likely course of a patient's disease.

14 Aug 2025

Colorectal cancer rates nearly triple among younger people in Sweden

According to a study by Karolinska Institutet, nearly three times as many people under the age of 50 in Sweden are diagnosed with colorectal cancer today compared with the early 1990s.

14 Aug 2025

Nudibranchs (sea slugs) emerge as a promising source of cancer drugs

Researchers reviewed the antitumor potential of bioactive compounds from nudibranchs, marine mollusks that acquire or synthesize potent chemical defenses. These compounds, often sourced from their diet, show promising cancer-fighting activity through mechanisms like DNA damage, oxidative stress, and apoptosis.

12 Aug 2025

Novel vaccine shows promise against KRAS-driven pancreatic and colorectal cancers

A novel cancer vaccine that stimulates the immune system to target one of the most common cancer-driving mutations has shown encouraging early results in patients with pancreatic and colorectal cancer, two of the most difficult-to-treat malignancies, according to a study led in part by investigators at the UCLA Health Jonsson Comprehensive Cancer Center.

12 Aug 2025