Colorectal Cancer

Colorectal Cancer is cancer that develops in the colon (the longest part of the large intestine) and/or the rectum (the last several inches of the large intestine before the anus). In the United States, it is the fourth most common cancer in men and women. Caught early, it is often curable.

What Causes Colorectal Cancer?

Cancer occurs when a normal cell divides and multiples uncontrollably. Normally cells are regulated in their growth, maturity, division and death by the DNA present in their nucleus. With damage to the DNA the cells may become rogue and multiply uncontrollably to give rise to tumors.

Colorectal Cancer Management

What is Colorectal Cancer?

Colorectal Cancer and Organ Preservation

Colorectal Cancer Symptoms

Colorectal Cancer Prognosis

Colorectal Cancer Pathogenesis

Colorectal Cancer Diagnosis

Microbial Dysbiosis and Colorectal Cancer

Colorectal Cancer Prevention

Latest Colorectal Cancer News and Research

Reducing alcohol consumption could ease Australia’s cancer burden

National data indicates that lowering alcohol consumption could prevent thousands of cancer deaths, emphasizing the importance of public health interventions.

27 Jan 2026

Lifetime alcohol consumption associated with higher risk of colorectal cancer

Studies have demonstrated a link between alcohol consumption and an elevated risk of colorectal cancer. New research now reveals that higher lifetime alcohol consumption is also associated with a higher risk,

26 Jan 2026

Colorblindness linked to delayed bladder cancer detection and higher mortality

Recognizing the sight of blood in urine, the most common first sign of bladder cancer, is often the impetus that leads people to a diagnosis.

24 Jan 2026

Discovery explains why people with IBD have higher risk of colorectal cancer

A chain of immune reactions in the gut—driven by a key signaling protein and a surge of white blood cells from the bone marrow—may help explain why people with inflammatory bowel disease (IBD) have a higher risk of colorectal cancer, according to a preclinical study by Weill Cornell Medicine investigators.

22 Jan 2026

Chemotherapy-induced gut changes trigger anti-metastatic immune response

Chemotherapy commonly damages the intestinal lining, a well-known side effect. But this injury does not remain confined to the gut.

22 Jan 2026

Reducing alcohol consumption could significantly lower cancer deaths

Reducing annual alcohol consumption in Australia by one litre a person could significantly lower deaths from several major cancers, particularly among older Australians, a new study led by La Trobe University has found.

21 Jan 2026

Nutrition experts call for dietary fiber recognition as an essential nutrient

Ōtākou Whakaihu Waka nutrition experts are calling for dietary fiber to be officially recognized internationally as an essential nutrient - the first 'new' essential nutrient in more than 50 years.

21 Jan 2026

Lung cancer deaths leveling off for EU women, except in Spain

After increasing for more than 25 years, lung cancer death rates are finally levelling off among women in European Union (EU) countries apart from Spain, according to predictions of mortality rates from the disease for 2026.

19 Jan 2026

Cancer mortality drops 34% as treatments and early detection improve

The 2026 cancer statistics reveal improved survival rates but highlight persistent inequities in cancer incidence and mortality across different populations.

16 Jan 2026

Novel liquid biopsy technology could advance cancer diagnostics and monitoring

A novel liquid biopsy technology is set to advance cancer diagnostics and monitoring by overcoming the long-standing challenge of simultaneously achieving high sensitivity, broad coverage, and simple workflow.

14 Jan 2026

Bacterial toxin shrinks tumors, enhances immune response in colorectal cancer study

A toxin secreted by cholera bacteria can inhibit the growth of colorectal cancer without causing any measurable damage to the body. This is shown by a new study by researchers at Umeå University, Sweden.

14 Jan 2026

Common food preservatives may raise cancer risk

Higher intake of certain food preservatives is associated with increased cancer rates, particularly breast and prostate cancers, highlighting safety concerns.

13 Jan 2026

DNA analysis of colorectal polyps improves diagnosis and treatment

In about 5–10% of colorectal cancer patients, hereditary factors play a role, with higher percentages among younger patients.

12 Jan 2026

New research decodes the bacterial “zip code” of colorectal cancer for prediction and survival

Bacterial communities in colorectal cancer reveal patterns linked to tumor genetics and patient outcomes, paving the way for personalized treatment strategies.

From BGI Genomics 9 Jan 2026

New federal guidelines shift cervical cancer screening to HPV testing

New cervical cancer screening guidelines emphasize self-collection and hrHPV testing, aiming to increase screening rates and improve women's health outcomes.

8 Jan 2026

Enveda’s third asset to the clinic with US FDA IND clearance: What it means for Inflammatory Bowel Disease

Enveda, a multi-asset clinical-stage biotech company pioneering the discovery and development of a new generation of small-molecule drugs derived from life’s chemistry, has announced that the US Food and Drug Administration (FDA) has cleared the Company’s Investigational New Drug (IND) application for ENV-6946.

From Hanson Wade Group - 4th Precision Medicine in Inflammatory Bowel Disease Summit 6 Jan 2026

AI language models actually help in digestive disease care

Large language models could transform digestive disorder management, but further RCTs are essential to validate their effectiveness and safety in healthcare.

6 Jan 2026

CT-based quantification of tumor fibrosis guides chemotherapy in pancreatic cancer

On October 3, 2025, a multicenter team from Shenzhen University, Xiangya Hospital of Central South University, Zhujiang Hospital of Southern Medical University, Wuxi People's Hospital Affiliated to Nanjing Medical University, among others jointly reported a novel noninvasive method for quantifying tumor fibrosis based on preoperative enhanced CT.

23 Dec 2025

Community awareness campaign helps improve early diagnosis of colorectal cancer in low-resource regions

In low-resource regions such as Nigeria, most people with colorectal cancer are diagnosed too late for curative treatment options.

22 Dec 2025

Opposing protein forces fine tune mRNA stability in human cells

A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and disorders - including cancers, neurodegenerative diseases and immune disorders - originate, as well as how to potentially treat them, according to researchers at Penn State.

16 Dec 2025