Colorectal Cancer

Colorectal Cancer is cancer that develops in the colon (the longest part of the large intestine) and/or the rectum (the last several inches of the large intestine before the anus). In the United States, it is the fourth most common cancer in men and women. Caught early, it is often curable.

Cured Meats, Nitrates, and Cancer Risk: Why Food Source and Processing Matter

From bacon and hot dogs to deli meats, cured meat products contain chemical compounds that increase the risk of cancer.

Microbial Dysbiosis and Colorectal Cancer

Colorectal Cancer Prognosis

Colorectal Cancer and Organ Preservation

Colorectal Cancer Prevention

What Causes Colorectal Cancer?

Colorectal Cancer Diagnosis

Colorectal Cancer Symptoms

What is Colorectal Cancer?

Colorectal Cancer Management

Colorectal Cancer Pathogenesis

Latest Colorectal Cancer News and Research

Combination therapy improves progression-free survival in dMMR/MSI-H metastatic colorectal cancer

Patients with deficient DNA mismatch repair (dMMR) or microsatellite instability-high (MSI-H) metastatic colorectal cancer experienced a 58% reduction in the risk of disease progression or death when treated with atezolizumab plus modified FOLFOX6 and bevacizumab compared with atezolizumab alone, according to results from the NRG-GI004/SWOG S1610 COMMIT trial published recently in the Journal of Clinical Oncology.

29 Jul 2026

AI model predicts cancer diagnoses up to a year in advance using routine clinical data

Researchers developed Oncoformer, a multimodal transformer that analyzes longitudinal health records and chest X-rays to classify cancer, predict diagnoses up to one year in advance, infer tumor stage, and forecast treatment response and recurrence risk. Validation across large independent cohorts showed strong performance, although prospective trials in diverse, average-risk populations are needed before clinical use.

28 Jul 2026

New AI tool predicts bowel cancer relapse risk from routine slides

A new artificial intelligence (AI) tool developed by La Trobe University researchers could help predict which stage-two bowel cancer patients are at risk of relapse, in an advance that could ultimately lead to thousands getting life-saving treatment earlier.

28 Jul 2026

New strategy combines cancer immunotherapy and gene therapy in a single nanoparticle

Cancer cells survive by hiding from the immune system's surveillance. A KAIST research team has developed a new anticancer platform that makes cancer cells send out their own danger signal—prompting immune cells to attack—while simultaneously delivering gene therapy.

28 Jul 2026

AI reveals effective combination therapy for advanced rectal cancer

Artificial intelligence developed by researchers at UCL has revealed a promising combination of cancer treatments that could help patients with locally advanced rectal cancer live longer.

27 Jul 2026

Mass-producible immune cells fight solid human tumors in mice

Off-the-shelf and mass-producible immune cells fight solid human tumors engrafted into mice. The Kobe University development is a significant contribution towards faster and cheaper cancer immunotherapy.

23 Jul 2026

Study reveals how p53 mutations cause tumors to resist cancer immunotherapy

Immune checkpoint blockade (ICB) therapy has transformed cancer treatment, but many tumors remain resistant.

22 Jul 2026

New blood test improves colorectal cancer recurrence risk prediction

A single preoperative blood sample may help improve the prediction of recurrence or metastasis in patients with colorectal cancer.

21 Jul 2026

New tumor organoids strengthen precision oncology research

Significant advances have been made in the development of patient-derived tumor "organoids" for preclinical research, in two new studies led by Weill Cornell Medicine investigators.

20 Jul 2026

New biological feedback loop helps the immune system attack colorectal cancers

A subset of cancers, known as microsatellite instability (MSI) and deficient DNA mismatch repair (dMMR) cancers, are more visible to the immune system than others.

16 Jul 2026

Six-gene signature predicts colorectal cancer recurrence after liver metastases

Researchers at The University of Texas MD Anderson Cancer Center identified a six-gene signature in microscopic colorectal cancer (CRC) liver metastases that may help predict recurrence after treatment.

9 Jul 2026

Nine gut bacteria linked to future type 2 diabetes risk

Research identifies specific gut microbes associated with future type 2 diabetes risk, emphasizing the impact of dietary fiber on microbiome health.

9 Jul 2026

Sexual and gender minority populations are less likely to receive cancer screening

A study reveals significant disparities in cancer screening rates among sexual and gender minorities, highlighting the need for equitable healthcare access.

8 Jul 2026

Yogurt, prebiotics, and probiotics link to lower colorectal cancer odds in U.S. adults

A national NHANES analysis of 9,405 U.S. adults aged 50 and older found that any yogurt, prebiotic, or probiotic consumption was associated with about 50% lower odds of self-reported colorectal cancer. Because the study was cross-sectional, it cannot prove causation but supports further research into microbiota-targeted dietary strategies.

8 Jul 2026

Microbiome science merges with oncology for better cancer treatments

Cancer remains notoriously difficult to treat, partly because tumors co‑opt their surrounding environment, including the resident microbiota, to evade immune surveillance and resist conventional therapies.

7 Jul 2026

Persistent disparities found in preventive cancer care for sexual and gender minority populations

New research has uncovered persistent disparities in preventive cancer care across different sexual orientation and gender identity (SOGI) populations.

6 Jul 2026

New study highlights noninvasive biomarkers for colorectal cancer detection

Emerging discoveries in liquid biomarker research promise to transform early detection, diagnosis, and treatment monitoring of colorectal cancer (CRC), according to a new study, offering less invasive alternatives to traditional methods that often require surgical interventions or tissue biopsies.

6 Jul 2026

Allergies show a small but significant link to later cancer risk

A systematic review and meta-analysis of 28 cohort-based studies found a weak but statistically significant association between allergic diseases and later cancer incidence. The signal was strongest in the Western Pacific region and among people with asthma, but high heterogeneity and limited subgroup evidence mean the findings require caution.

5 Jul 2026

Blood test may predict which colorectal cancer patients benefit from chemotherapy

A blood test may help identify which patients with colorectal cancer that has spread to the liver are most likely to benefit from chemotherapy after surgery, according to research presented today at the ESMO Gastrointestinal Cancers Congress 2026.

3 Jul 2026

Feeder-free TIL expansion system makes advanced cancer immunotherapy safer

Conventional TIL therapy, clinically validatedrecently with the U.S. Food and Drug Administration approval of lifileucel for advanced melanoma,stillfaces substantial hurdles.

3 Jul 2026