Colorectal Cancer

Colorectal Cancer is cancer that develops in the colon (the longest part of the large intestine) and/or the rectum (the last several inches of the large intestine before the anus). In the United States, it is the fourth most common cancer in men and women. Caught early, it is often curable.

What Causes Colorectal Cancer?

Cancer occurs when a normal cell divides and multiples uncontrollably. Normally cells are regulated in their growth, maturity, division and death by the DNA present in their nucleus. With damage to the DNA the cells may become rogue and multiply uncontrollably to give rise to tumors.

What is Colorectal Cancer?

Colorectal Cancer Diagnosis

Colorectal Cancer Prevention

Colorectal Cancer Management

Colorectal Cancer Prognosis

Colorectal Cancer Symptoms

Colorectal Cancer Pathogenesis

Microbial Dysbiosis and Colorectal Cancer

Colorectal Cancer and Organ Preservation

Latest Colorectal Cancer News and Research

Pilot study will provide data for further testing of gut microbiome analysis

The intestinal microbiota, composed by the microorganisms that live in our intestines, can give us information about our health, since its composition may depend on factors such as the diet, the lifestyle or our pathologies.

31 Mar 2020

AI could enhance prediction of treatment response among patients with non-small cell lung cancer

Artificial intelligence deep learning algorithms may predict response to systemic treatment for non-small cell lung cancer.

23 Mar 2020

AI may help predict tumor sensitivity to systemic cancer therapies

Using standard-of-care computed tomography scans in patients with advanced non-small cell lung cancer, researchers utilized artificial intelligence to train algorithms to predict tumor sensitivity to three systemic cancer therapies.

20 Mar 2020

Trial of cancer drug OxaliTex promises lower toxicity and more robust action

Preclinical trials indicate that a drug candidate called OxaliTex can stop the growth of cancer cells completely. OxaliTex appears to be more potent than many other common chemotherapy drugs, with less toxicity and less rapidly counteracted by mechanisms of drug resistance. The study was reported in the journal Proceedings of the National Academy of Sciences in March 2020.

16 Mar 2020

Bowel cancer on the up in England’s young adults

A new study published in March 2020, in the British Journal of Surgery (BJS), shows that the number of young adults with bowel cancer is rising at an alarming rate in England.

11 Mar 2020

Exploiting careless cancer cells to develop new drugs

Could the ability of cancer cells to quickly alter their genome be used as a weapon against malignant tumors? Researchers at Uppsala University have succeeded in developing a substance that has demonstrated promising results in experiments on both animal models and human cancer cells.

11 Mar 2020

NCCN publishes recommendations for assessing quality improvements in cancer care

The National Comprehensive Cancer Network has published a curated list of high-impact measures for assessing quality improvements in cancer care.

10 Mar 2020

Study finds dramatic increase in the incidence of bowel cancer among adults under 50

There has been a dramatic increase in the incidence of bowel cancer in adults under the age of 50, according to new research from the University of Bristol, UWE Bristol and University Hospitals Bristol NHS Foundation Trust.

10 Mar 2020

Colorectal cancer rates are increasing rapidly among young adults, study reveals

A population-based analysis from England indicates that the incidence of colorectal cancer is increasing rapidly in young adults.

10 Mar 2020

Automated CT-based biomarkers can better predict cardiovascular events than standard methods

Researchers at the National Institutes of Health and the University of Wisconsin have demonstrated that using artificial intelligence to analyze CT scans can produce more accurate risk assessment for major cardiovascular events than current, standard methods such as the Framingham risk score and body-mass index.

5 Mar 2020

Burden of colorectal cancer is rapidly shifting to younger individuals

The burden of colorectal cancer is swiftly shifting to younger individuals as incidence increases in young adults and declines in older age groups, according to the latest edition of Colorectal Cancer Statistics 2020, a publication of the American Cancer Society.

5 Mar 2020

Inhibiting specific protein could make radiation therapy for colon cancer more effective

Researchers at Washington University School of Medicine in St. Louis appear to have discovered a way to make radiation therapy for colorectal cancer more effective by inhibiting a protein found in cancer cells in the gut.

3 Mar 2020

Study: Five-year survival rate for adolescents and young adults with cancer has improved

The five-year survival rate for adolescents and young adults with cancer has significantly improved from 1975 to 2005 in the United States overall, but this was not the case for all cancers, according to a report in the Journal of the National Cancer Institute.

3 Mar 2020

Canada's cancer burden will increase in 2020 as population ages

Nearly 1 in 2 Canadians are expected to receive a diagnosis of cancer in their lifetime, and cancer is the leading cause of death in the country.

2 Mar 2020

Aggressive cancers set up a structural framework to keep the immune system at bay

Aggressive colorectal cancers set up an interactive network of checkpoints to keep the immune system at bay, scientists report.

26 Feb 2020

Breast cancer cells hibernate in the lung before forming secondary tumors

Healthy lung cells support the survival of breast cancer cells, allowing them to hibernate in the lung before forming secondary tumors, according to new research from the Crick.

24 Feb 2020

Researchers study why colon cancer is more lethal in pediatric and young adult patients

Colon cancer is more likely to be lethal in children and young adults than middle-aged adults. In a single-institution study, researchers at The University of Texas MD Anderson Cancer Center, Houston, Tex., found that differences in mortality rates persist regardless of whether pediatric, adolescent, and young adult patients (aged 24 and younger) were born with a predisposition for colon abnormalities or disease and for the first time conclude that young people are more likely to have metastases outside the colon, into the abdominal cavity, when they are diagnosed.

23 Feb 2020