Colorectal Cancer News and Research

Latest Colorectal Cancer News and Research

Navigating the dual role of B cells in tumor immunity

B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME).

3 Jun 2025

Exercise after chemo key for colon cancer survival, study finds

Post-chemotherapy exercise significantly boosts disease-free survival in colon cancer patients, underscoring the importance of structured physical activity.

3 Jun 2025

Experts chart path to bring microbiome science into routine clinical care

Despite rapid advances in sequencing and bioinformatics, translating microbiome science into clinical practice presents significant challenges, including the lack of standardized protocols, limited clinical evidence, and logistical barriers. This Cell perspective outlines key actions, standardization, robust trial design, and clinician education to move microbiome diagnostics and therapeutics from bench to bedside.

2 Jun 2025

Anti-inflammatory diet linked to longer survival in colon cancer patients

Patients with colon cancer who consumed an anti-inflammatory diet during a phase 3 clinical trial showed longer overall survival post-treatment compared to those on a proinflammatory diet, according to a Dana-Farber Cancer Institute analysis.

1 Jun 2025

Cancer survivor population in the US expected to surpass 22 million by 2035

The number of people living with a history of cancer in the United States is estimated at 18.6 million as of January 1, 2025 and projected to exceed 22 million by 2035, according to a new report, Cancer Treatment and Survivorship Statistics, 2025, led by the American Cancer Society (ACS).

31 May 2025

Triplet therapy significantly improves survival in BRAF V600E-mutated metastatic colorectal cancer

First-line treatment with the triplet combination of encorafenib, cetuximab and mFOLFOX6 significantly improved survival compared to the standard of care in patients with BRAF V600E-mutated metastatic colorectal cancer, according to new data from the Phase III BREAKWATER trial led by researchers from The University of Texas MD Anderson Cancer Center.

30 May 2025

TRR 417 initiative aims to unlock new treatments for colorectal cancer

In the realm of colorectal cancer treatments beyond surgery and radiation, one key question gained prominence in recent years: Is the tumor's DNA repair system defective, making it "microsatellite unstable"? Around 15 to 20 percent of all tumors have this trait, making them likely candidates for successful immunotherapy.

30 May 2025

Study reveals rising toll of alcohol-linked cancer mortality across the United States

A new study led by experts at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, is the first to look at trends over time in alcohol-linked cancer mortality across the United States.

29 May 2025

New biomarkers could help improve detection and treatment of gastrointestinal diseases

Scientists have discovered a range of 'biomarkers' that could help to improve detection and treatment of gastrointestinal diseases (GIDs) such as gastric cancer (GC), colorectal cancer (CRC), and inflammatory bowel disease (IBD).

28 May 2025

New insights reveal EGFR as a target in KRAS-mutated colon cancer

KRAS mutations are among the most common genetic alterations in cancer and are considered particularly difficult to treat.

26 May 2025

Machine learning tool identifies metabolic clues in colorectal cancer

Scientists aiming to advance cancer diagnostics have developed a machine learning tool that is able to identify metabolism-related molecular profile differences between patients with colorectal cancer and healthy people.

22 May 2025

Meta analysis highlights prognostic role of circPVT1 in solid tumors

circPVT1 has emerged as a key regulator in disease progression and clinical outcomes. However, its prognostic relevance and association with clinicopathological parameters in solid malignancies remain to be fully elucidated.

22 May 2025

Gut bacteria help ease chemotherapy side effects and aid recovery

Intestinal microbes that survive chemo can rid the gut of excess chemo drugs and produce a vitamin that helps to stem nausea.

21 May 2025

Long noncoding RNA ESSENCE identified as key driver of colorectal cancer progression

Colorectal cancer (CRC) remains one of the most prevalent and deadly cancers worldwide, with rising incidence linked to dietary and lifestyle changes.

18 May 2025

RANBP2 identified as key regulator in the progression of multiple solid tumors

The nuclear pore complex protein RANBP2 has emerged as a critical factor in the development and progression of various solid malignancies.

12 May 2025

GLP-1RAs show added protection against cancer beyond weight reduction

New research being presented at this year's European Congress on Obesity (ECO) in Malaga, Spain (11-14 May) and published in the journal eClinicalMedicine finds that first generation weight-loss medications like liraglutide and exenatide appear to show anti-cancer benefits beyond weight loss.

11 May 2025

Cancer rates are climbing in younger adults and researchers want to know why

A new NIH-led study finds rising rates of 14 cancer types in Americans under 50, especially breast, colorectal, kidney, uterine, and pancreatic cancers. The research urges deeper investigation into shared risk factors and earlier screening strategies.

8 May 2025