Cystic Fibrosis News and Research

Latest Cystic Fibrosis News and Research

Modifier gene offers a likely explanation for less infection in some patients with cystic fibrosis

Cystic fibrosis is caused by an inherited mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

10 Dec 2019

New tool can rapidly reveal unintended changes made by CRISPR-directed gene editing

Amidst rising hopes for using CRISPR gene editing tools to repair deadly mutations linked to conditions like cystic fibrosis and sickle cell disease, a new study in the Nature journal Communications Biology describes a new innovation that could accelerate this work by rapidly revealing unintended and potentially harmful changes introduced by a gene editing process.

6 Dec 2019

New technology developed for treatment of children suffering from respiratory diseases

A new technology to unblock and remove secretions from the respiratory tract of children has been developed as part of a collaboration between researchers at Ben-Gurion University of the Negev and its affiliated Soroka University Medical Center, Cincinnati Children's Hospital Medical Center, and the University of Cincinnati.

4 Dec 2019

New treatment approach could improve outcomes for people with cystic fibrosis

A new approach to treating people with cystic fibrosis (CF) has been shown to reduce inflammation, which has the potential to reduce the need for lung transplants and lower the risk of death.

3 Dec 2019

For artist inspired by illness, ‘gratitude outweighs pain’

People often ask Dylan Mortimer how it feels to breathe through transplanted lungs. He gets that a lot because while most people go through life with one pair of lungs, Mortimer is on his third.

2 Dec 2019

State-of-the-art expert reviews provide insights into vitamin D research

Vitamin D is essential for human health. Although much is known about its important role in bone metabolism and in certain areas of non-skeletal health, there are many open questions and topics of debate.

27 Nov 2019

Dangerous bacteria send out warning signals when attacked by antibiotics

A bacterial infection is not just an unpleasant experience - it can also be a major health problem. Some bacteria develop resistance to otherwise effective treatment with antibiotics.

22 Nov 2019

Breakthrough therapy could improve health and survival in people with cystic fibrosis

Researchers at the Children's Hospital Colorado Breathing Institute, one of the largest cystic fibrosis clinical care centers in the U.S., are part of a Therapeutics Development Network that oversaw clinical trials leading to FDA approval of TRIKAFTA, a new, highly-effective CF treatment for people with CF 12 years of age and older.

20 Nov 2019

Pioneering CRISPR therapy leaves two patients free of blood disease symptoms

The first two clinical trials for CRISPR-based treatments for inherited blood disorders have been successful.

20 Nov 2019

Study could open new avenues for antibacterial treatments

Scientists have revealed how common respiratory bugs that cause serious infections in people with cystic fibrosis interact together, according to a new study in eLife.

12 Nov 2019

Clinical benefit of anticoagulants for atrial fibrillation decreases with age, shows study

The net clinical benefit of anticoagulants for atrial fibrillation (AF) -- one of the most important causes of irregular heartbeats and a leading cause of stroke -- decreases with age, as the risk of death from other factors diminishes their benefit in older patients, according to a study led by researchers at UC San Francisco.

11 Nov 2019

Eisai transfers rights to Royalty Pharma relating to net sales of EZH2 inhibitor outside of Japan

Eisai Co., Ltd. announced today that it has entered into an agreement to transfer the rights to receive royalties on the sales outside of Japan for an investigational anti-cancer agent tazemetostat (generic name) to Royalty Pharma.

5 Nov 2019

Researchers produce synthetic phages that attack broader range of bacterial strains

Bacteriophages ("phages" for short) are viruses that infect bacteria. Phages are highly host-specific and will typically only infect and kill an individual species or even subspecies of bacteria. Compared to conventional antibiotics, phages do not indiscriminately kill bacteria.

4 Nov 2019

UI scientists are developing new delivery tools for gene editing

News of advances in gene-editing technology raises the prospect of actually using this approach to treat disease in patients. But one of the hurdles that remains is how to deliver these tools to the right cells in the patients safely and efficiently.

31 Oct 2019

Three-drug combination improves lung function, reduces symptoms in CF patients

A phase three clinical trial that UT Southwestern participated in determined that a three-drug combination improved lung function and reduced symptoms in cystic fibrosis patients who have a single copy of the most common genetic mutation for the disease.

31 Oct 2019

Anti-inflammatory agents can safely, effectively reduce symptoms of major depression

Anti-inflammatory agents, such as aspirin/paracetamol, statins, and antibiotics, can safely and effectively curb the symptoms of major depression, finds a pooled analysis of the available evidence, published online in the Journal of Neurology Neurosurgery & Psychiatry.

29 Oct 2019

New cystic fibrosis drug now available through NHS England

On October 24, 2019, cystic fibrosis (CF) patients rejoiced at the news that three years of talks between the UK’s National Institute for Health and Care Excellence (NICE) and Vertex Pharmaceuticals had succeeded in a compromise which could see about 5,000 patients gaining access to a potentially life-saving drug called Orkambi within the next month. Orkambi is perceived to be a ‘wonder drug’ because it helps these patients to breathe easier and better, and can be started as young as two years.

28 Oct 2019

Glycans in mucus are responsible for microbe-taming, study reveals

More than 200 square meters of our bodies -- including the digestive tract, lungs, and urinary tract -- are lined with mucus. In recent years, scientists have found some evidence that mucus is not just a physical barrier that traps bacteria and viruses, but it can also disarm pathogens and prevent them from causing infections.

14 Oct 2019

Combination drug appears to improve lung health in patients with cystic fibrosis, but with caveats

In adolescent and adult patients with cystic fibrosis taking lumacaftor-ivacaftor (ORKAMBI), the combination drug appears to improve lung function and body weight and reduce the need for intravenous antibiotic treatment, according to a French study published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

11 Oct 2019

Peripherally inserted central catheters associated with serious allergic reactions in patients

Peripherally inserted central catheters (PICCs) that use a magnetized tip to guide insertion were associated with serious allergic reactions in patients, according to a study published today in Infection Control & Hospital Epidemiology, the journal for the Society for Healthcare Epidemiology of America. Severe adverse reactions occurred in patients within minutes of PICC insertion.

8 Oct 2019

Cystic Fibrosis News and Research

Latest Cystic Fibrosis News and Research

Modifier gene offers a likely explanation for less infection in some patients with cystic fibrosis

New tool can rapidly reveal unintended changes made by CRISPR-directed gene editing

New technology developed for treatment of children suffering from respiratory diseases

New treatment approach could improve outcomes for people with cystic fibrosis

For artist inspired by illness, ‘gratitude outweighs pain’

State-of-the-art expert reviews provide insights into vitamin D research

Dangerous bacteria send out warning signals when attacked by antibiotics

Breakthrough therapy could improve health and survival in people with cystic fibrosis

Pioneering CRISPR therapy leaves two patients free of blood disease symptoms

Study could open new avenues for antibacterial treatments

Clinical benefit of anticoagulants for atrial fibrillation decreases with age, shows study

Eisai transfers rights to Royalty Pharma relating to net sales of EZH2 inhibitor outside of Japan

Researchers produce synthetic phages that attack broader range of bacterial strains

UI scientists are developing new delivery tools for gene editing

Three-drug combination improves lung function, reduces symptoms in CF patients

Anti-inflammatory agents can safely, effectively reduce symptoms of major depression

New cystic fibrosis drug now available through NHS England

Glycans in mucus are responsible for microbe-taming, study reveals

Combination drug appears to improve lung health in patients with cystic fibrosis, but with caveats

Peripherally inserted central catheters associated with serious allergic reactions in patients

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

Cystic Fibrosis News and Research

Latest Cystic Fibrosis News and Research

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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