Cystic Fibrosis

Cystic fibrosis is a life threatening, inherited disease of the exocrine glands. The condition primarily affects the digestive and respiratory systems which become clogged with a thick, sticky mucus. Cystic fibrosis is caused by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene which results in an excess of salt and water passing into cells, causing a thick, sticky mucus to build up in bodily passageways.

Cystic Fibrosis (CF)

Cystic fibrosis is a genetic condition that affects the production and flow of mucus within the lungs and digestive system, parts of the body that then become clogged with a thick, sticky mucus.

Cystic Fibrosis Causes

Cystic Fibrosis Symptoms

Cystic Fibrosis Diagnosis

Cystic Fibrosis Treatment

Genetics of Cystic Fibrosis

Cystic Fibrosis Screening

Cystic Fibrosis Questions

Coping With Cystic Fibrosis

Cystic Fibrosis Facts

Cystic Fibrosis Epidemiology

Cystic Fibrosis Prognosis

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Cystic Fibrosis Research

Could CRISPR Repair CFTR in Cystic Fibrosis Patients?

Sweat Test for Cystic Fibrosis

Cystic Fibrosis and Salty Skin

Cystic Fibrosis Evolution

Lung Transplantation for Cystic Fibrosis

Gene Therapy as a Potential Cure for Cystic Fibrosis

Cystic Fibrosis and Infertility

Cystic Fibrosis History

Tests for Cystic Fibrosis During Pregnancy

Latest Cystic Fibrosis News and Research

Learning health system approach offers a powerful route to improving NHS efficiency, report suggests

Researchers are calling on policy makers to support the use of data-driven learning health systems to deliver a step change in the NHS's ability to improve patient care.

30 Sep 2022

Vitamin supplements can benefit cystic fibrosis patients, study suggests

Cystic fibrosis patients who supplement their diet with vitamin C can also derive greater benefit from another antioxidant, vitamin E, resulting in a reduction in damaging inflammation, a study led by Oregon State University suggests.

28 Sep 2022

Investing in the next generation of researchers, Beckman Coulter Life Sciences announces call for grant applications

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, announces its continuing commitment to the next generation of researchers and scientists with a call for registrations for its SPRI Grants for Genomic Research.

From Beckman Coulter Life Sciences 27 Sep 2022

Newborns get routine heel blood tests, but should states keep those samples

Close to 4 million babies are born in the United States every year, and within their first 48 hours nearly all are pricked in the heel so their blood can be tested for dozens of life-threatening genetic and metabolic problems.

14 Sep 2022

Manuka honey could cure serious lung infections caused by drug-resistant bacterium

In a recent study published in the journal Microbiology, researchers demonstrated that incorporating Manuka honey into nebulized antibiotic treatment could effectively combat respiratory infections due to Mycobacterium abscessusus, offering a novel new therapeutic strategy for M. abscessus management.

13 Sep 2022

First-of-its-kind messenger RNA therapy developed for ovarian cancer, cachexia

Researchers at Oregon State University and Oregon Health & Science University have developed a promising, first-of-its-kind messenger RNA therapy for ovarian cancer as well as cachexia, a muscle-wasting condition associated with cancer and other chronic illnesses.

13 Sep 2022

Experts join forces to create a gold standard document to help people with cystic fibrosis

World leading experts have joined forces to create a gold standard document to help people living with Cystic Fibrosis.

7 Sep 2022

Combination therapy regimen for cystic fibrosis is also beneficial to primary school-aged children

Cystic fibrosis remains an incurable genetic disorder which impairs lung function and significantly reduces life expectancy.

8 Aug 2022

Study finds disparities in first evaluation of infants with cystic fibrosis from minoritized groups

Infants from minoritized racial and ethnic backgrounds who have positive newborn screening tests for cystic fibrosis received their diagnostic follow-up for the disease later than recommended and later than white, non-Hispanic infants, according to a study published in the Journal of Cystic Fibrosis.

27 Jul 2022

Parents become drug developers to save their children’s lives

Maggie Carmichael wasn't developing like other kids. As a toddler, she wasn't walking and had a limited vocabulary for her age.

21 Jul 2022

As Big Pharma loses interest in new antibiotics, infections are only growing stronger

Forget covid-19, monkeypox, and other viruses for the moment and consider another threat troubling infectious disease specialists: common urinary tract infections, or UTIs, that lead to emergency room visits and even hospitalizations because of the failure of oral antibiotics.

15 Jul 2022

BU researcher wins Cystic Fibrosis Foundation's Harry Shwachman Clinical Investigator Award

Andrew Berical, MD, Assistant Professor of Medicine at Boston University School of Medicine (BUSM), is the recipient of the Harry Shwachman Clinical Investigator Award from the Cystic Fibrosis Foundation (CFF).

12 Jul 2022

Emory researchers identify key immune cell type that drives the transition from early to late COVID-19

Determining how SARS-CoV-2, the virus causing COVID-19, moves from an early stage of infection, when patients are largely asymptomatic, into a later stage when people may experience life-threatening inflammation in the lungs, is a critical step in understanding how to target and treat the disease more efficiently.

14 Jun 2022

Using a harmless amoeba to protect children from dangerous infections

Innovative efforts at the University of Virginia School of Medicine to use a harmless amoeba to protect children from dangerous infections has won critical financial support from The Hartwell Foundation.

10 Jun 2022

Cryo-EM helps scientists to decipher the structure of a key part of RNA degradation machinery

In biology, getting rid of stuff can be just as important as making it. A buildup of cells, proteins, or other molecules that are no longer needed can cause problems, so living things have evolved several ways to clean house.

9 Jun 2022

Largest-ever series of case studies shows phage therapy’s success in more than half of the patients

The number of reported cases using viruses to treat deadly Mycobacterium infections just went up by a factor of five. In a new study, a team led by researchers from the University of Pittsburgh and the University of California San Diego report 20 new case studies on the use of the experimental treatment, showing the therapy's success in more than half of the patients.

9 Jun 2022

Inhibiting immune response-related enzyme holds promise in preventing or treating severe COVID-19

Blocking an immune response-related enzyme holds promise in preventing or treating severe COVID-19 symptoms by reducing inflammation, tissue injury and blood clots in the lungs, new research in mice suggests.

1 Jun 2022

Aston University’s new antibiotic combination forms part of a lifesaving treatment for cystic fibrosis

A new antibiotic combination developed by researchers at Aston University has formed part of a lifesaving treatment used in the USA.

26 May 2022

Hydration restores airway integrity in people with cystic fibrosis

Cystic fibrosis is a rare genetic disease which can cause very serious symptoms. In particular, patients suffer from chronic bacterial infections that can lead to respiratory failure.

24 May 2022

UH experts in cloning and stem cell science take the first step toward unraveling cystic fibrosis

Two nationally recognized experts in cloning and stem cell science from the University of Houston are taking the first step toward limiting the consequences of chronic inflammation in cystic fibrosis (CF) by identifying the source of this persistent and enigmatic inflammation in CF lungs.

24 May 2022