Cystic Fibrosis

Cystic fibrosis is a life threatening, inherited disease of the exocrine glands. The condition primarily affects the digestive and respiratory systems which become clogged with a thick, sticky mucus. Cystic fibrosis is caused by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene which results in an excess of salt and water passing into cells, causing a thick, sticky mucus to build up in bodily passageways.

Cystic Fibrosis (CF)

Cystic fibrosis is a genetic condition that affects the production and flow of mucus within the lungs and digestive system, parts of the body that then become clogged with a thick, sticky mucus.

Cystic Fibrosis Symptoms

Cystic Fibrosis Epidemiology

Cystic Fibrosis Causes

Tests for Cystic Fibrosis During Pregnancy

Cystic Fibrosis History

Genetics of Cystic Fibrosis

Cystic Fibrosis Treatment

Gene Therapy as a Potential Cure for Cystic Fibrosis

Cystic Fibrosis and Salty Skin

Sweat Test for Cystic Fibrosis

Cystic Fibrosis Prognosis

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Cystic Fibrosis Evolution

Coping With Cystic Fibrosis

Cystic Fibrosis Research

Cystic Fibrosis Diagnosis

Cystic Fibrosis Questions

Cystic Fibrosis and Infertility

Latest Cystic Fibrosis News and Research

New biofilm discovery may pave way to undermining antibiotic-resistant Pseudomonas

The bacterium known as Pseudomonas aeruginosa is an unwelcome visitor in the human body. Serious infections can result when a bunch of these bugs settle together on a surface to form a biofilm - a community of microbes like the slime on spoiled food, but in this case residing inside a person.

29 Oct 2025

New gene-editing method can correct many disease-causing mutations in mammalian cells

Some genetic disorders-such as cystic fibrosis, hemophilia and Tay Sachs disease-involve many mutations in a person's genome, often with enough variation that even two individuals who share the same disorder might have a different combination of mutations.

23 Oct 2025

Ozone exposure weakens lung function and reshapes the oral microbiome

Ozone exposure reshapes the oral microbiome and reduces lung function, particularly in men, revealing significant health risks associated with pollution.

1 Oct 2025

Engineers create designer biobots using human lung cells

A brand-new engineering approach to generate "designer" biological robots using human lung cells is underway in Carnegie Mellon University's Ren lab.

26 Sep 2025

Pediatric lung transplantation shows promising outcomes in China

Lung transplantation has transformed care for patients with end-stage respiratory failure, particularly among adults, where the number of procedures has grown dramatically over recent decades.

25 Sep 2025

New screening method boosts efficiency and accuracy of CAST genome editing

Natural systems such as CRISPR-associated transposons (CASTs) offer a targetable, one-step way to edit genomes.

23 Sep 2025

Innovative RNA editing offers hope beyond CRISPR

Genetic editing holds promise to treat incurable diseases, but the most popular method - CRISPR - sometimes does more harm than good.

18 Sep 2025

New technology could make MRI scanners cost-effective and more accessible

Revolutionary new technology could make MRI scanners cost effective, more widely available to local communities and help save lives, thanks to a pioneering collaboration between the University of Sheffield and GE HealthCare.

8 Sep 2025

WHO expands essential medicines lists with new cancer and diabetes treatments

Today, the World Health Organization (WHO) has released updated editions of its Model Lists of Essential Medicines (EML) and Essential Medicines for Children (EMLc), adding new treatments for various types of cancer and for diabetes with associated comorbidities such as obesity.

5 Sep 2025

Genetic variants influencing vitamin D synthesis, metabolism, and transport

A Canadian review synthesizes genetic factors that influence vitamin D synthesis, metabolism, and transport, highlighting how polymorphisms affect circulating levels. It also explores how gene-environment interactions shape individual responses to supplementation and sunlight.

20 Aug 2025

Researchers solve longstanding mystery of protein release in cells

It's known as biology's central dogma: All living organisms' genetic information is stored in DNA, which is transcribed into RNA, which is translated into proteins that perform nearly all essential tasks in a cell.

5 Aug 2025

Experimental drug found to be safe and effective in treating children with MIS-C

In a small trial, Mass General Brigham researchers found a drug designed to treat Celiac disease supported a more rapid return to normal activities for patients following COVID.

30 Jul 2025

Largest Indian genome study reveals 50,000 years of genetic history

With around 5,000 different ethno-linguistic and religious groups, India is one of the most culturally and genetically diverse countries in the world.

26 Jun 2025

Pandorabactins help pathogenic bacteria compete for iron in the lungs

An interdisciplinary research team led by the Leibniz-HKI in Jena has discovered a new group of bioactive natural compounds in pathogenic bacteria of the genus Pandoraea: pandorabactins.

19 Jun 2025

Breakthrough drug delivery system transports genetic therapies directly to the lungs

Scientists have made a key breakthrough for treating respiratory diseases by developing a new drug delivery system that transports genetic therapies directly to the lungs, opening promising possibilities for patients with conditions like lung cancer and cystic fibrosis.

5 Jun 2025

Yeast cells offer promising alternative for manufacturing DNase1

The protein DNase1 is one of the oldest biological agents in history: It has been on the market since 1958 and is now used, among other things, to treat cystic fibrosis.

28 May 2025

New cryogenic mass spectrometry approach reveals inner structure of lipid nanoparticles

Scientists have developed a method for analysing the structure of lipid nanoparticles that could be used to improve vaccine and drug delivery, targeting a wide range of health issues.

23 May 2025

Trump’s team cited safety in limiting covid shots. patients, health advocates see more risk.

Larry Saltzman has blood cancer. He's also a retired doctor, so he knows getting covid-19 could be dangerous for him — his underlying illness puts him at high risk of serious complications and death.

23 May 2025

Long COVID linked to rising anxiety and depression in children

A new study from Kennedy Krieger Institute is calling attention to an emerging mental health crisis among children with long COVID. Researchers found that nearly 40% of pediatric patients with long COVID reported feeling significant symptoms of anxiety or depression.

20 May 2025

Targeting brain neurons to successfully treat type 2 diabetes

Successfully treating type 2 diabetes may involve focusing on brain neurons, rather than simply concentrating on obesity or insulin resistance, according to a study published today in the Journal of Clinical Investigation.

15 May 2025