Cystic Fibrosis

Cystic fibrosis is a life threatening, inherited disease of the exocrine glands. The condition primarily affects the digestive and respiratory systems which become clogged with a thick, sticky mucus. Cystic fibrosis is caused by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene which results in an excess of salt and water passing into cells, causing a thick, sticky mucus to build up in bodily passageways.
Cystic Fibrosis (CF)

Cystic fibrosis is a genetic condition that affects the production and flow of mucus within the lungs and digestive system, parts of the body that then become clogged with a thick, sticky mucus.

Read More

Overview

Feature Articles

Latest Cystic Fibrosis News and Research

A path to treat currently untreatable cases of cystic fibrosis is clearly achievable, study suggests

A path to treat currently untreatable cases of cystic fibrosis is clearly achievable, study suggests

Researchers discover new set of signals that control production of goblet cells in the lung

Researchers discover new set of signals that control production of goblet cells in the lung

High levels of neutrophil extracellular traps found in airways of severely ill Covid-19 patients

High levels of neutrophil extracellular traps found in airways of severely ill Covid-19 patients

Wayne State awarded NSF grant to investigate how viruses navigate through the mucus barrier

Wayne State awarded NSF grant to investigate how viruses navigate through the mucus barrier

Citizens’ jury set to reflect deeply on the pros and cons of human genome editing

Citizens’ jury set to reflect deeply on the pros and cons of human genome editing

Researchers demonstrate a potentially powerful strategy for treating cystic fibrosis

Researchers demonstrate a potentially powerful strategy for treating cystic fibrosis

Enterprise Therapeutics doses first subjects in Phase I trial for novel cystic fibrosis therapy ETD001

Enterprise Therapeutics doses first subjects in Phase I trial for novel cystic fibrosis therapy ETD001

Novel nanotechnology could change the lives of people living with cystic fibrosis

Novel nanotechnology could change the lives of people living with cystic fibrosis

Novel 'CopyCatcher' detects when precise copying of genetic information takes place in cells

Novel 'CopyCatcher' detects when precise copying of genetic information takes place in cells

CFTR modulator can be safe, well-tolerated for younger children with common form of cystic fibrosis

CFTR modulator can be safe, well-tolerated for younger children with common form of cystic fibrosis

Study may lead to personalized treatments for cystic fibrosis

Study may lead to personalized treatments for cystic fibrosis

Study uncovers protein 'signature' of severe COVID-19

Study uncovers protein 'signature' of severe COVID-19

Study shows potential of human mesenchymal stem cells to treat chronic lung infections

Study shows potential of human mesenchymal stem cells to treat chronic lung infections

"COVID-19 diarrhea" depends on inflammatory response that is part of the disease

"COVID-19 diarrhea" depends on inflammatory response that is part of the disease

Two repurposed drugs and a blue dye show potential as SARS-CoV-2 entry inhibitors

Two repurposed drugs and a blue dye show potential as SARS-CoV-2 entry inhibitors

Study could lead to new ways of targeting harmful bacteria

Study could lead to new ways of targeting harmful bacteria

Novel approach to gene editing bypasses disease-causing mutations in a gene

Novel approach to gene editing bypasses disease-causing mutations in a gene

Five-year study aims to improve health of patients with cystic fibrosis across their growing lifespan

Five-year study aims to improve health of patients with cystic fibrosis across their growing lifespan

Biology of single-celled organisms reveals potential treatment target for COPD

Biology of single-celled organisms reveals potential treatment target for COPD

Rice bioengineer wins NIH support for a new strategy to fight cystic fibrosis

Rice bioengineer wins NIH support for a new strategy to fight cystic fibrosis