Cystic Fibrosis News and Research

Latest Cystic Fibrosis News and Research

New clinical practice guideline on home oxygen therapy for children

The American Thoracic Society has developed a new clinical practice guideline for home oxygen therapy for children. The guideline appears in the Feb. 1 edition of the Society's American Journal of Respiratory and Critical Care Medicine.

4 Feb 2019

Discovery of proteins that control mucin secretion reveals clues to treating colon, airway diseases

Cells produce mucins at a constant rate, and when exposed to an allergen or pathogen, they produce more mucin in a rapid burst. Both the constant and rapid mucin secretion is controlled by calcium.

1 Feb 2019

Combination of cystic fibrosis drugs found to be safe and effective in children aged 2-5 years

An open label Phase 3 study conducted at Ann & Robert H. Lurie Children's Hospital of Chicago and other centers established that a combination of cystic fibrosis drugs lumacaftor and ivacaftor is safe and effective in children aged 2-5 years, whose disease is caused by two copies of F508del-CFTR gene mutation - the most common and severe form of cystic fibrosis.

25 Jan 2019

Scientists explore bacterial immunity to better understand infectious disease

Patients with cystic fibrosis are often infected by pseudomonas aeruginosa, a bacterium that infects the lungs and prevents breathing, often causing death.

8 Jan 2019

Inhalable mRNA offers hope for patients with lung disease

Scientists have reported the success of an inhalable mRNA therapy that can induce the production of a target protein in the lungs of mice.

4 Jan 2019

Scientists discover new biomarkers for early detection of cystic fibrosis

Scientists at McMaster University have discovered several new biomarkers from a single drop of blood that could allow earlier and more definitive detection of cystic fibrosis, a genetic disease which strikes both children and adults, causing chronic problems with the digestive system and the lungs.

20 Dec 2018

Researchers identify link between mucus in the small airways and pulmonary fibrosis

A team of investigators led by members of the University of Colorado School of Medicine faculty at CU Anschutz Medical Campus has identified a connection between mucus in the small airways and pulmonary fibrosis.

18 Dec 2018

Blood test helps identify distinct molecular signatures in children with cystic fibrosis

Researchers at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago, and colleagues, used a blood test and microarray technology to identify distinct molecular signatures in children with cystic fibrosis.

12 Dec 2018

Researchers use INTEGRA's VIAFLO 96/384 to streamline the experimental workflow

Researchers are using INTEGRA’s VIAFLO 96/384 multichannel electronic pipette to study Pseudomonas aeruginosa.

From INTEGRA Biosciences 12 Dec 2018

New massive sequencing platform implemented for double factor preimplantation genetic testing

A research team from the Universitat Autònoma de Barcelona, in collaboration with the Blood and Tissue Bank of Catalonia, has managed to implement a massive sequencing platform for Preimplantation Genetic Testing for the first time in history.

5 Dec 2018

Antibiotics can effectively target and eliminate senescent cells

ANTIBIOTICS have emerged as potentially lifespan-enhancing drugs, according to the results of new research carried out in the UK.

28 Nov 2018

Citrate-based biomaterial could help in better bone repair

A material based on a natural product of bones and citrus fruit, called citrate, provides the extra energy that stem cells need to form new bone tissue, according to a team of Penn State bioengineers.

27 Nov 2018

Scientists discover toxic bullet involved in bacterial competition

A bacterial toxin that allows an infectious strain of bacteria to defeat its competitors has been discovered by Imperial College London scientists.

20 Nov 2018

New technology based on moths and magnets could help treat genetic diseases

A new technology that relies on a moth-infecting virus and nanomagnets could be used to edit defective genes that give rise to diseases like sickle cell, muscular dystrophy and cystic fibrosis.

14 Nov 2018

Study identifies factors tied to greater risk of advanced liver disease in cystic fibrosis patients

Children's Hospital Colorado pediatric gastroenterologist, Michael Narkewicz, MD, recently shared results of the Prospective Study of Ultrasound to Predict Hepatic Cirrhosis in Cystic Fibrosis, which sought to determine if liver ultrasounds could identify children and adolescents with cystic fibrosis who are at greater risk of developing advanced liver disease.

13 Nov 2018

Hypertonic saline shown to aid breathing in cystic fibrosis babies

The first-ever randomized controlled trial on babies with CF has found that treatment with inhaled hypertonic saline can improve breathing and lung health.

9 Nov 2018

Determine goals of healthcare before making healthcare-related choices

What are the goals of healthcare? That very question must be asked more frequently before healthcare-related choices are made.

7 Nov 2018

Vertex gets European CHMP positive opinion for KALYDECO to treat patients with cystic fibrosis

Vertex Pharmaceuticals (Europe) Limited today announces that the European Medicines Agency's Committee for Medicinal Products for Human Use adopted a positive opinion for KALYDECO (ivacaftor) to include the treatment of people with cystic fibrosis (CF) aged 12 to <24 months who have at least one of the following nine mutations in their cystic fibrosis transmembrane conductance regulator gene: G551D, G1244E, G1349D, G178R, G551S, S1251N, S1255P, S549N or S549R.

22 Oct 2018

Synspira’s abstracts accepted for presentation at the 32nd Annual NACFC

Synspira, a privately held company developing a new class of inhaled glycopolymer-based therapeutics for the treatment of pulmonary disease, today announced that three abstracts have been accepted for presentation at the 32nd Annual North American Cystic Fibrosis Conference, occurring October 18-20 in Denver, CO.

12 Oct 2018

Hopkins gastroenterologists use endoscopic procedure to deliver therapeutic genes to the liver

Fixing or replacing faulty genes has emerged as a key to unlocking cures for numerous devastating diseases. But if the new, engineered genes can't find their way into the patient's genomic sequence, they won't help.

3 Oct 2018

Cystic Fibrosis News and Research

Latest Cystic Fibrosis News and Research

New clinical practice guideline on home oxygen therapy for children

Discovery of proteins that control mucin secretion reveals clues to treating colon, airway diseases

Combination of cystic fibrosis drugs found to be safe and effective in children aged 2-5 years

Scientists explore bacterial immunity to better understand infectious disease

Inhalable mRNA offers hope for patients with lung disease

Scientists discover new biomarkers for early detection of cystic fibrosis

Researchers identify link between mucus in the small airways and pulmonary fibrosis

Blood test helps identify distinct molecular signatures in children with cystic fibrosis

Researchers use INTEGRA's VIAFLO 96/384 to streamline the experimental workflow

New massive sequencing platform implemented for double factor preimplantation genetic testing

Antibiotics can effectively target and eliminate senescent cells

Citrate-based biomaterial could help in better bone repair

Scientists discover toxic bullet involved in bacterial competition

New technology based on moths and magnets could help treat genetic diseases

Study identifies factors tied to greater risk of advanced liver disease in cystic fibrosis patients

Hypertonic saline shown to aid breathing in cystic fibrosis babies

Determine goals of healthcare before making healthcare-related choices

Vertex gets European CHMP positive opinion for KALYDECO to treat patients with cystic fibrosis

Synspira’s abstracts accepted for presentation at the 32nd Annual NACFC

Hopkins gastroenterologists use endoscopic procedure to deliver therapeutic genes to the liver

Industry Focus: Cell & Gene Therapy eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

Cystic Fibrosis News and Research

Latest Cystic Fibrosis News and Research

Industry Focus: Cell & Gene Therapy eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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