Diabetes News and Research

Latest Diabetes News and Research

Positive Phase II/III clinical data from ChemoCentryx' PROTECT-1 Traficet-EN trial

ChemoCentryx, Inc., announced today that Phase II/III clinical data from the Company's PROTECT-1 (the Prospective Randomized Oral Therapy Evaluation in Crohn's disease Trial) of Traficet-EN(TM) (CCX282-B) in patients with moderate-to-severe Crohn's disease demonstrated clinical efficacy with a favorable safety and tolerability profile. The

25 Nov 2009

Health watch: When you eat just as vital to what you eat

When you eat may be just as vital to your health as what you eat, found researchers at the Salk Institute for Biological Studies. Their experiments in mice revealed that the daily waxing and waning of thousands of genes in the liver—the body's metabolic clearinghouse—is mostly controlled by food intake and not by the body's circadian clock as conventional wisdom had it.

25 Nov 2009

Incyte enters into collaboration and license agreement with Novartis

Incyte Corporation (NASDAQ: INCY) announced today that it has entered into a collaboration and license agreement with Novartis for two of its investigational hematology-oncology therapies: INCB18424, an oral JAK1/JAK2 inhibitor that is in Phase III development for myelofibrosis, a serious life-threatening neoplastic condition characterized by varying degrees of bone marrow failure, splenic enlargement and debilitating constitutional symptoms, and INCB28060, an oral cMET inhibitor that is about to enter Phase I development as a potential treatment for multiple cancers.

25 Nov 2009

CXCL5 molecule causes insulin resistance and type 2 diabetes in obese people

Many people who are overweight or obese develop insulin resistance and type 2 diabetes at some stage in their lives. A European research team has now discovered that obese people have large amounts of the molecule CXCL5, produced by certain cells in fatty tissue.

25 Nov 2009

Comparison study finds no significant differences in post-transplant survival rates of NASH and ETOH groups

Researchers at the University of Miami School of Medicine compared the outcomes of cirrhotic patients who underwent liver transplants for nonalcoholic steatohepatitis (NASH) versus alcoholic liver disease (ETOH) and found no statistically significant differences in post-transplant survival rates between the NASH and ETOH groups

25 Nov 2009

Seniors with chronic pain more at risk of falls

Chronic pain is experienced by as many as two out of three older adults. Now, a new study finds that pain may be more hazardous than previously thought, contributing to an increased risk of falls in adults over age 70. The findings appear in the November 25 issue of The Journal of the American Medical Association (JAMA).

24 Nov 2009

Shanghai Biolaxy receives IND approval for insulin formulation to treat diabetes

Shanghai Biolaxy announced the Chinese State Food & Drug Administration (SFDA) has approved the investigational new drug application (IND) for its oral insulin project (Nodlin), an innovative insulin formulation to treat diabetes. This IND approval allows Biolaxy to initiate its first phase I clinical study.

24 Nov 2009

Therapeutic agents in soy can treat colon cancer, says study

A study conducted by Children's Hospital & Research Center Oakland scientists identifies a new class of therapeutic agents found naturally in soy that can prevent and possibly treat colon cancer, the third most deadly form of cancer. Sphingadienes (SDs) are natural lipid molecules found in soy that research shows may be the key to fighting colon cancer.

24 Nov 2009

Medical advances abound while surgeons report concerns about medical errors

The Wall Street Journal reports on "20 health-care advances to give thanks for this Thanksgiving." Among the most key: "Life expectancy in the U.S. reached an all-time high of 77.9 years in 2007, the latest year for which statistics are available, continuing a long upward trend. (That's 75.3 years for men and 80.4 years for women.) ... Death rates dropped significantly for eight of the 15 leading causes of death in the U.S., including cancer, heart disease, stroke, hypertension, accidents, diabetes, homicides and pneumonia, from 2006 to 2007."

24 Nov 2009

RESTAURANT SURVIVAL GUIDE in the EAT THIS, NOT THAT! book series released

The authors of the bestselling EAT THIS, NOT THAT! book series, with more than five million copies in print, today released the ultimate reference book for making the most effective food choices while dining at your favorite restaurants — EAT THIS, NOT THAT! RESTAURANT SURVIVAL GUIDE by David Zinczenko, with Matt Goulding.

24 Nov 2009

Roche, Spanish Department of Health to collaborate in Medical Genome Project

Roche and the Department of Health of Junta de Andalucía, Spain have signed an agreement for a cooperation in the Medical Genome Project (MGP), a research project created to analyse the genomes of people with rare diseases and identify the defective gene or genes causing the disease and its behaviour.

From Roche Sequencing and Life Science 24 Nov 2009

Studies demonstrate clinical utility of Given Imaging's PillCam SB capsule endoscopy

Given Imaging Ltd., the global leader in patient-friendly GI diagnostic and monitoring solutions, today announced three new studies that demonstrate the clinical utility of PillCam SB capsule endoscopy in providing physicians with critical information on how they manage and/or diagnose intestinal disorders. These novel studies were carried out in pediatric patients with gastrointestinal symptoms, including children with known or suspected Crohn's disease.

24 Nov 2009

Second-quarter fiscal 2010 results announced by Medtronic

Medtronic, Inc. today announced financial results for its second quarter of fiscal year 2010, which ended Oct. 30, 2009.

24 Nov 2009

Presence of increased body fat hinders the loss of body weight

The presence of increased body fat, and therefore higher levels of inflammatory substances in the blood, hinders the loss and maintenance of body weight; as shown by a research project of the University of Navarra conducted by Estíbaliz Goyenechea Soto, a scientist at the School of Pharmacy.

24 Nov 2009

C.A.R.E. Clinic in New Orleans attended by over 1000 patients

Organizers of a free health clinic for uninsured residents of Louisiana are pleased with its success today. Not only did the clinic see 1,000 patients, it may have saved the lives of some sick individuals. Many of the patients had not seen a physician since Hurricane Katrina struck the Gulf Coast in 2005.

24 Nov 2009

Pharmacy-based intervention improves antipsychotic adherence among patients with mental illnesses

Health systems should consider pharmacy-based interventions when involving patients who have poor follow-through taking medication.

24 Nov 2009

New MEMS sensor may help clinicians distinguish stable and unstable plaque during cardiac emergencies

University of Sourthern California biomedical engineer and cardiologist Tzung "John" Hsiai hopes to develop a new tool to help clinicians distinguish cardiac emergencies requiring immediate surgery from chronic problems manageable with drugs and lifestyle change.

24 Nov 2009

DSS sets evidence-based guidelines and definitions to treat type 2 diabetes

A first-of-its-kind consensus statement on diabetes surgery is published online today in the Annals of Surgery. The report illustrates the findings of the first international consensus conference -- Diabetes Surgery Summit (DSS) -- where an international group of more than 50 scientific and medical experts agreed on a set of evidence-based guidelines and definitions that are meant to guide the use and study of gastrointestinal surgery to treat type 2 diabetes. The document is considered to be the foundation of diabetes surgery as a medical discipline of its own.

24 Nov 2009

2009-10 AACP Student Community Engaged Service Award announced

Four student-led community engagement projects will be awarded the 2009-10 AACP Student Community Engaged Service Award for their outstanding programs delivering consumer education about medication use, expanding access to affordable healthcare and improving the public’s health.

24 Nov 2009

Team-based care and medical homes may improve chronic disease management

Patients whose hypertension is managed by a physician-pharmacist team have lower blood pressure levels and are more likely to reach goals for blood pressure control than those treated without this collaborative approach, according to a report in the November 23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

24 Nov 2009