Dopamine News and Research

Latest Dopamine News and Research

Dopamine agonists reduce motor complications in Parkinson's disease, but increase other side-effects

Dopamine agonists are increasingly used to treat people with Parkinson's disease, but there is a debate about how well they work.

17 Apr 2008

Exposure to organic solvents linked to disturbances in brain circuitry

Chronic occupational exposure to organic solvents, found in materials such as paints, printing and dry cleaning agents, is widespread all over the world, and is thought to damage the central nervous system.

16 Apr 2008

Elevated levels of antioxidant urate may slow Parkinson's progression

Naturally elevated levels of the antioxidant urate may slow the progression of Parkinson's disease in men. Researchers from the MassGeneral Institute for Neurodegenerative Disease (MGH-MIND) and Harvard School of Public Health (HSPH) examined data from an earlier study and found that, among recently diagnosed Parkinson's patients, those with the highest urate levels had a significantly slower rate of disease progression during the two-year study period.

15 Apr 2008

Blood urate levels associated with the progression of Parkinson's disease

Higher blood levels of the compound urate, a salt derived from uric acid that is associated with gout, may be associated with a slower progression of Parkinson's disease, according to an article posted online today that will appear in the June 2008 print issue of Archives of Neurology.

15 Apr 2008

Repeated methamphetamine use causes long-term adaptations in brains of mice

Repeatedly stimulating the mouse brain with methamphetamine depresses important areas of the brain, and those changes can only be undone by re-introducing the drug, according to research at the University of Washington and other institutions.

10 Apr 2008

Methamphetamine addiction mechanism discovered

Researchers have identified, for the first time, long-term changes in the brain circuitry of methamphetamine-addicted mice that can explain why the craving of addiction is so stubborn and long-lived.

10 Apr 2008

Negligent, attentive mouse mothers show biological differences

In mice, child neglect is a product of both nature and nurture, according to a new study.

9 Apr 2008

Parkinson transplants survive at least 16 years

Transplanted cells can survive in the brain for over one and half decade. However, some of the transplanted cells developed Parkinson-like features which is very surprising.

9 Apr 2008

Expert warns of anti-psychotic drugs use in children

Research from Britain is suggesting that an increasing number of children are being prescribed anti-psychotic drugs to treat a range of conditions which are not licensed for use in children.

9 Apr 2008

Anticipation of laughter reduces levels of stress hormones

In 2006 researchers investigating the interaction between the brain, behavior, and the immune system found that simply anticipating a mirthful laughter experience boosted health-protecting hormones.

8 Apr 2008

Identification of dopamine 'mother cells' could lead to future Parkinson's treatments

'Mother cells' which produce the neurons affected by Parkinson's disease have been identified by scientists, according to new research published in the journal Glia.

8 Apr 2008

Transplanted dopamine neurons are affected by the Parkinson's disease process

A new groundbreaking study published in Nature Medicine has implications for the future of transplantation and stem cell therapies as a treatment for Parkinson's disease.

7 Apr 2008

Occupational therapists use Wii for Parkinson's study

It's Ingrid Bell's turn at bat. She steps up to the plate, awaiting the pitch. A 70-mph fastball soars toward her. She swings and connects with the ball.

7 Apr 2008

Fetal cells transplanted into the brain to treat Parkinson's may not function long term

Neurons grafted into the brain of a patient with Parkinson's disease fourteen years ago have developed Lewy body pathology, the defining pathology for the disease, according to research by Jeffrey H. Kordower, PhD, and associates and published in the April 6 issue of Nature Medicine.

7 Apr 2008

Aripiprazole has potential for treating alcohol dependence

Aripiprazole is currently approved to treat bipolar disorder as well as schizophrenia. A new study has found that it significantly and dose-dependently increases the sedative effects of alcohol and, to a lesser degree, decreases the euphoric effects of alcohol. Future research will need to examine the beneficial versus the side effects of aripiprazole for treatment of alcohol dependence.

4 Apr 2008

Mouse calls help search for emotion-controlling genes

Scientists have long known that emotions and other personality traits and disorders run together in families.

3 Apr 2008

Stimulant treatment for ADHD does not contribute to substance abuse later in life

Treating children as early as age six or seven with stimulants for Attention Deficit Hyperactivity Disorder (ADHD) is not likely to increase risk of substance abuse as adults, according to two studies funded by the National Institutes of Health (NIH).

2 Apr 2008

The brain can sense the calories in food, independent of taste

Their finding that the brain's reward system is switched on by this “sixth sense” machinery could have implications for understanding the causes of obesity. For example, the findings suggest why high-fructose corn syrup, widely used as a sweetener in foods, might contribute to obesity.

28 Mar 2008

Therapeutic cloning treats Parkinson's disease in mice

Research led by investigators at Memorial Sloan-Kettering Cancer Center (MSKCC) has shown that therapeutic cloning, also known as somatic-cell nuclear transfer (SCNT), can be used to treat Parkinson's disease in mice.

25 Mar 2008