Dopamine News and Research

Latest Dopamine News and Research

High sugar, high fat diets during pregnancy may cause infants to become junk food junkies

A new research report published online in The FASEB Journal suggests that pregnant mothers who eat high sugar and high fat diets have babies who are likely to become junk food junkies themselves. According to the report, which used rats, this happens because the high fat and high sugar diet leads to changes in the fetal brain's reward pathway, altering food preferences.

24 Mar 2011

Researchers discover a type of 'cellular bilingualism' in brain

A team of researchers from the University of Montreal and McGill University have discovered a type of "cellular bilingualism" - a phenomenon that allows a single neuron to use two different methods of communication to exchange information.

18 Mar 2011

Gene therapy holds promise for Parkinson's treatment

A first-of-its-kind study of gene therapy in the treatment of Parkinson's disease determined that half of all patients who received the treatment had "clinically meaningful improvements" of their symptoms within six months of surgery.

17 Mar 2011

The Lancet Neurology publishes Neurologix NLX-P101 Phase 2 trial results against PD

Neurologix, Inc., announced today that the results of the Company's Phase 2 clinical trial for its novel, investigational gene therapy NLX-P101 for the treatment of Parkinson's disease were published in an online-first edition of The Lancet Neurology.

17 Mar 2011

Results from first successful phase 2 trial of gene therapy for Parkinson's or any neurologic disorder

A gene therapy called NLX-P101 dramatically reduces movement impairment in Parkinson's patients, according to results of a Phase 2 study published today in the journal Lancet Neurology. The approach introduces a gene into the brain to normalize chemical signaling.

16 Mar 2011

Euthymics Bioscience initiates EB-1010 phase 2b/3a TRIADE clinical trial for major depressive disorder

Euthymics Bioscience, Inc. today announced the initiation of an advanced clinical study of its lead product candidate EB-1010 for the treatment of major depressive disorder (MDD). The TRIADE (Triple Reuptake Inhibitor Anti-Depressant Effects) trial is a phase 2b/3a clinical trial designed to assess the safety and efficacy of EB-1010, a novel serotonin-preferring triple reuptake inhibitor.

14 Mar 2011

NeuroDerm commences ND0611 Phase I/II trial to treat Parkinson's disease

NeuroDerm, Ltd. announced today the enrollment of the first group of patients in its Phase I/II clinical trial of ND0611, a new patch for the treatment of Parkinson's disease.

9 Mar 2011

Parkinson's disease medication turns on critical gene, protects brain cells

In a major breakthrough in the battle against Parkinson's disease, researchers at the University of Colorado School of Medicine have discovered a drug that stops the progression of the degenerative illness in mice and is now being tested in humans.

9 Mar 2011

Unique gene therapy to combat Parkinson's disease

Physicians at Rush University Medical Center are testing a unique gene therapy product called CERE-120 to evaluate if its use can improve the symptoms of Parkinson's disease. Rush is one of 11 sites in the U.S. and the only site in Illinois enrolling patients into the new, double-blinded trial.

9 Mar 2011

Scientists find link between ADHD and bipolar disorders with regard to rapid mood swings

Thanks in part to a Norwegian research biobank, researchers have generated important new insight into ADHD and how the condition manifests itself. Among other things, they have found that there is some overlap between ADHD and bipolar disorders with regard to rapid mood swings.

2 Mar 2011

Brain's reward/motivation circuits linked to compulsive overeating

A brain imaging study at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory reveals a subtle difference between ordinary obese subjects and those who compulsively overeat, or binge: In binge eaters but not ordinary obese subjects, the mere sight or smell of favorite foods triggers a spike in dopamine - a brain chemical linked to reward and motivation.

1 Mar 2011

Protein pathway may hold a clue for understanding Parkinson's disease

A protein pathway that may hold the secret to understanding Parkinson's disease has been discovered and explained by Iowa State University researchers.

1 Mar 2011

Scientists suggest that lateral habenula can be a prime locus of human depression

A team of neuroscientists at Cold Spring Harbor Laboratory, Brookhaven National Laboratory and UC San Diego has collected evidence suggesting that a previously overlooked portion of the brain could be a prime locus of human depression.

24 Feb 2011

Brain reward center responds to good and bad experiences

The so-called reward center of the brain may need a new name, say scientists who have shown it responds to good and bad experiences. The finding, published in PLoS One, may help explain the "thrill" of thrill-seeking behavior or maybe just the thrill of surviving it, according to scientists at Georgia Health Sciences University and East China Normal University.

23 Feb 2011

Forest Labs enters definitive merger agreement to acquire Clinical Data

Forest Laboratories, Inc. and Clinical Data, Inc. today announced that they have entered into a definitive merger agreement pursuant to which Forest will acquire Clinical Data, a specialty pharmaceutical company focused on the development of first-in-class and best-in-category therapeutics, for $30.00 per share in cash plus contingent consideration of up to $6.00 per share that may be paid upon achievement of certain commercial milestones related to Viibryd.

22 Feb 2011

Amphetamine linked to development of Parkinson’s disease

New research suggests that taking prescription amphetamines may raise the risk of developing Parkinson’s disease later. But, the researchers noted that the study did not prove a cause-and-effect relationship and further investigation is warranted. The research was released Feb. 19, and is scheduled to be presented in April at the American Academy of Neurology’s annual meeting in Honolulu.

21 Feb 2011

Amphetamines appear to increase risk of developing Parkinson's disease: New research

New research shows people who have used amphetamines such as benzedrine and dexedrine appear to be at an increased risk of developing Parkinson's disease, according to a study released today that will be presented at the American Academy of Neurology's 63rd Annual Meeting in Honolulu April 9 to April 16, 2011.

20 Feb 2011

First evidence of neurotrophic factors improving status of degenerating dopamine neurons in Parkinson's brains

Ceregene, Inc., a biopharmaceutical company, reported today that its scientists and collaborators have published new experimental findings in support of its Parkinson's disease program which appeared as the lead article in the current issue of Movement Disorders. The publication reports the first evidence that gene transfer can provide targeted expression of a neurotrophic factor, i.e., neurturin or NRTN, intended to restore and preserve dying neurons.

17 Feb 2011

WINCS detects and measures serotonin levels in brain through deep brain stimulation

Mayo Clinic researchers have concluded that, through deep brain stimulation, a Wireless Instantaneous Neurotransmitter Concentration System (WINCS) can detect and measure serotonin levels in the brain. The findings suggest that in the future such measurements of serotonin may help establish a therapeutic mechanism of deep brain stimulation for psychiatric disease.

16 Feb 2011

CX3CL1 signaling chemical can offer better understanding of Parkinson's disease

Targeting the neuroinflammatory causes of Parkinson's disease with a naturally present brain chemical signal could offer a better understanding of the clinical mechanisms of the disease and open a future therapeutic window, reports a team of researchers from the University of South Florida Department Neurosurgery and Brain Repair and the James A. Haley Veterans' Administration Hospital, Tampa.

14 Feb 2011

Dopamine News and Research

Latest Dopamine News and Research

High sugar, high fat diets during pregnancy may cause infants to become junk food junkies

Researchers discover a type of 'cellular bilingualism' in brain

Gene therapy holds promise for Parkinson's treatment

The Lancet Neurology publishes Neurologix NLX-P101 Phase 2 trial results against PD

Results from first successful phase 2 trial of gene therapy for Parkinson's or any neurologic disorder

Euthymics Bioscience initiates EB-1010 phase 2b/3a TRIADE clinical trial for major depressive disorder

NeuroDerm commences ND0611 Phase I/II trial to treat Parkinson's disease

Parkinson's disease medication turns on critical gene, protects brain cells

Unique gene therapy to combat Parkinson's disease

Scientists find link between ADHD and bipolar disorders with regard to rapid mood swings

Brain's reward/motivation circuits linked to compulsive overeating

Protein pathway may hold a clue for understanding Parkinson's disease

Scientists suggest that lateral habenula can be a prime locus of human depression

Brain reward center responds to good and bad experiences

Forest Labs enters definitive merger agreement to acquire Clinical Data

Amphetamine linked to development of Parkinson’s disease

Amphetamines appear to increase risk of developing Parkinson's disease: New research

First evidence of neurotrophic factors improving status of degenerating dopamine neurons in Parkinson's brains

WINCS detects and measures serotonin levels in brain through deep brain stimulation

CX3CL1 signaling chemical can offer better understanding of Parkinson's disease

Forensics and toxicology - Industry Focus eBook eBook

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

Dopamine News and Research

Latest Dopamine News and Research

Forensics and toxicology - Industry Focus eBook eBook

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

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