Down Syndrome News and Research

Latest Down Syndrome News and Research

Men have a biological clock too and produce poor quality sperm as they age

Researchers in the U.S. say that even though men are able to father children well into old age, the quality of the sperm declines as men age.

6 Jun 2006

Comprehensive care for complex, high-risk pregnancies

As many as 3 percent of all pregnancies result in the birth of a baby with chromosomal anomalies like Down syndrome or structural anomalies such as congenital heart disease.

23 May 2006

Amyloid protein content in the brain linked to Alzheimer's disease risk

Researchers from the Flanders Interuniversity Institute for Biotechnology (VIB) connected to the University of Antwerp are the first to show that the quantity of amyloid protein in brain cells is a major risk factor for Alzheimer's disease. Amyloid protein has already been known to be the primary component of the senile plaques in the brains of patients. The new discovery demonstrates that the greater the quantity of the protein that is produced, the younger the dementia patient is.

28 Apr 2006

Rapamycin (sirolimus) may be effective in treating kidney disease

A widely available drug may be effective in treating kidney disease, report scientists at the University of California, Santa Barbara. They describe the discovery in the online edition of the Proceedings of the National Academies of Science.

21 Mar 2006

Hand-held device brings speech to impaired

A middle-aged woman makes plans over the telephone to get together with a friend, even though she cannot talk after suffering a stroke.

24 Feb 2006

Cellular discovery suggests possibilities for drug therapy for kidney disease

Scientists at the University of California, Santa Barbara have reported a discovery at the cellular level that suggests possibilities for drug therapy for kidney disease.

13 Feb 2006

Chinese medicine shows promise as treatment for sperm genetic abnormalities

Bioscientists from the University of Kent have called for clinical trials to further investigate how traditional Chinese medicine (TCM) may have a positive effect on sperm genetic abnormalities, and thereby influence the success rate of male infertility treatment.

2 Feb 2006

Treatment of down syndrome in mice restores nerve growth in cerebellum

Researchers at Johns Hopkins restored the normal growth of specific nerve cells in the cerebellum of mouse models of Down syndrome (DS) that were stunted by this genetic condition. The cerebellum is the rear, lower part of the brain that controls signals from the muscles to coordinate balance and motor learning.

25 Jan 2006

National estimates for 18 specific major birth defects between 1999 and 2001

Cleft lip is a treatable birth defect, but for the families of the estimated 6,800 U.S. infants born with one, it's a heartbreaking experience – not only because of the associated health problems, but because friends and family may ignore the condition or because of social stigma associated with facial defects.

5 Jan 2006

Hippocampal myo-inositol and cognitive ability in adults with Down Syndrome

Researchers from the Institute of Psychiatry at King's College London have identified a molecule that could be targeted to treat the cognitive impairment in people with Down syndrome.

7 Dec 2005

New screening test can predict Down syndrome in first trimester

According to new research, an early blood test has proven to be an accurate predictor for Down syndrome.

13 Nov 2005

Screening test would give hope to childless couples

According to new research thousands of childless British couples could greatly improve their chances of having a baby if a test that weeds out faulty embryos were carried out.

20 Oct 2005

Nitric oxide could one day help women in their 30s and 40s remain fertile longer

Researchers have found that an important chemical compound, nitric oxide, appears to slow or reverse the aging of eggs in mouse ovaries. The finding suggests nitric oxide could one day help women in their 30s and 40s remain fertile longer and increase their chances of having healthy babies, the scientists say.

7 Sep 2005

Changes to prenatal genetic testing could mean more babies born with abnornalities

A study in the UK suggests that a proposed change to the type of prenatal genetic testing offered to couples in the UK, could possibly result in certain chromosome abnormalities being missed.

4 Jul 2005

Birth abnormality rates could increase if proposed changes to prenatal testing go ahead

A proposed change to the type of prenatal genetic testing offered to couples in the UK could result in certain chromosome abnormalities being missed, suggests a study published online today (Thursday June 30, 2005) by The Lancet.

1 Jul 2005

New initiative to provide $600k to fund new research into Down Syndrome

Today the University of Colorado and The Anna and John J. Sie Foundation of Denver announced The Sie Family Down Syndrome Break-Through Research Initiative. The initiative will provide $600,000 in grant funds to stimulate new scientific research on Down syndrome with the aim of enhancing cognitive ability. These are the first such grants provided to CU for a specific chromosomal condition and the first nationwide specifically for Down syndrome.

1 Jul 2005

Study is the first to identify involvement of chromosome 21 in developmental regression autism

A new Cincinnati Children's Hospital Medical Center study links regions of two chromosomes to susceptibility for a type of autism characterized by regression in development. Developmental regression can include the loss of previously acquired language, social skills or both.

8 Jun 2005

Baby boy is first successful birth in Canada from frozen eggs

McGill University Health Center (MUHC) in Montreal yesterday announced the first successful birth in Canada resulting from frozen eggs. A healthy baby boy, weighing 3740 grams was born on April 29 to a 26-year-old mother who had suffered from infertility for two years.

31 May 2005

Study tackles aging issues of adults with developmental disabilities

Some 4.5 million Americans have a developmental disability. As people live longer, adults with developmental disabilities are no exception, yet their conditions also bring aging-related challenges. A new study by UCLA and Casa Colina Centers for Rehabilitation reports that a geriatric evaluation and follow-up visits by a nurse practitioner can detect and reduce health problems in this population that often go unaddressed by the healthcare system.

23 May 2005

Protein Mnd2 protects chromosome bonds

The protein Mnd2 inhibits premature separation of chromosomes during the formation of gametes. The now published discovery of this regulatory function may help to understand the origin of some common congenital chromosome defects.

30 Mar 2005