Down Syndrome

Down syndrome is a chromosomal abnormality characterized by the presence of an extra copy of genetic material on the 21st chromosome, either in whole (Trisomy 21) or in part (such as due to translocations). The effects of the extra copy vary greatly among people, depending on the extent of the extra copy, genetic history and pure chance. In 2007, the American College of Obstetricians and Gynecologists (ACOG) endorsed guidelines that offer risk assessment to all pregnancies for fetal chromosomal abnormalities, including Down syndrome. It is estimated that approximately 70%, or 2.8 million, women undergo Down syndrome screening in the United States each year.
What is Down Syndrome?

Down syndrome or Down's syndrome, is a congenital condition that usually causes some degree of learning disability and is typically characterized by certain physical features.

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Latest Down Syndrome News and Research

Study shows potential benefits of green tea extracts in Down syndrome

Study shows potential benefits of green tea extracts in Down syndrome

Adults with Down syndrome more likely to die from COVID-19 than general population

Adults with Down syndrome more likely to die from COVID-19 than general population

New partnership launches Down syndrome research biobank

New partnership launches Down syndrome research biobank

Woman’s right to disclosure of stillbirth could be achieved through a tort claim

Woman’s right to disclosure of stillbirth could be achieved through a tort claim

Pandemic sends a couple into indefinite long distance though just miles apart

Pandemic sends a couple into indefinite long distance though just miles apart

Vanderbilt researcher proposes an explanatory paradigm for the cause of autism

Vanderbilt researcher proposes an explanatory paradigm for the cause of autism

Study: Prenatal screening in Europe has reduced the number of babies born with Down syndrome

Study: Prenatal screening in Europe has reduced the number of babies born with Down syndrome

High error rates found in human egg cells

High error rates found in human egg cells

New study finds link between gestational age and ADHD in children with Down syndrome

New study finds link between gestational age and ADHD in children with Down syndrome

Experimental drug can reverse age-related memory decline in mice

Experimental drug can reverse age-related memory decline in mice

Study outlines a new role for pregnancy-associated plasma protein A in gestational diabetes

Study outlines a new role for pregnancy-associated plasma protein A in gestational diabetes

Research can bring new possibilities for earlier diagnosis, preventive treatment of dementia

Research can bring new possibilities for earlier diagnosis, preventive treatment of dementia

AI can help recognize individuals with congenital adrenal hyperplasia based on facial images

AI can help recognize individuals with congenital adrenal hyperplasia based on facial images

NIH awards grant totaling $19.5M for Down syndrome research project

NIH awards grant totaling $19.5M for Down syndrome research project

Happiness neurotransmitter serotonin plays role in evolutionary expansion of the neocortex

Happiness neurotransmitter serotonin plays role in evolutionary expansion of the neocortex

$109 million NIH grant awarded to expand Alzheimer's disease and Down syndrome research

$109 million NIH grant awarded to expand Alzheimer's disease and Down syndrome research

Excess genetic exchanges impede the segregation of chromosomes into eggs

Excess genetic exchanges impede the segregation of chromosomes into eggs

Study underscores value of Mass General’s online health tool about Down syndrome

Study underscores value of Mass General’s online health tool about Down syndrome

Fly brain structure governed by lineage-dependent repulsion mechanism between neurons

Fly brain structure governed by lineage-dependent repulsion mechanism between neurons

Specific gene impairment may also protect people with Down syndrome

Specific gene impairment may also protect people with Down syndrome