Down Syndrome

Down syndrome is a chromosomal abnormality characterized by the presence of an extra copy of genetic material on the 21st chromosome, either in whole (Trisomy 21) or in part (such as due to translocations). The effects of the extra copy vary greatly among people, depending on the extent of the extra copy, genetic history and pure chance. In 2007, the American College of Obstetricians and Gynecologists (ACOG) endorsed guidelines that offer risk assessment to all pregnancies for fetal chromosomal abnormalities, including Down syndrome. It is estimated that approximately 70%, or 2.8 million, women undergo Down syndrome screening in the United States each year.
What is Down Syndrome?

Down syndrome or Down's syndrome, is a congenital condition that usually causes some degree of learning disability and is typically characterized by certain physical features.

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Latest Down Syndrome News and Research

COVID found to be the leading cause of death for people with intellectual and developmental disabilities

COVID found to be the leading cause of death for people with intellectual and developmental disabilities

GnRH therapy could improve cognitive deficits in men with Down syndrome

GnRH therapy could improve cognitive deficits in men with Down syndrome

Study addresses food texture challenges in the life of children with Down syndrome

Study addresses food texture challenges in the life of children with Down syndrome

Simple blood test can accurately detect Alzheimer's disease in people with Down syndrome

Simple blood test can accurately detect Alzheimer's disease in people with Down syndrome

Study gains new insights into heart and lung conditions in babies born with Down Syndrome

Study gains new insights into heart and lung conditions in babies born with Down Syndrome

Vaccines and monoclonal antibodies being developed for respiratory syncytial virus

Vaccines and monoclonal antibodies being developed for respiratory syncytial virus

Gen Zs with Down syndrome have high aspirations and a great zest for life, study reveals

Gen Zs with Down syndrome have high aspirations and a great zest for life, study reveals

Music could be a powerful tool to help mothers promote infant development

Music could be a powerful tool to help mothers promote infant development

Shared decision-making training program for nurses to support Down syndrome screening decisions

Shared decision-making training program for nurses to support Down syndrome screening decisions

"Selfish chromosomes" explain why most human embryos die very early on, study suggests

"Selfish chromosomes" explain why most human embryos die very early on, study suggests

Antiretroviral drug used to treat HIV ameliorates cognitive deficits in mouse model of Down syndrome

Antiretroviral drug used to treat HIV ameliorates cognitive deficits in mouse model of Down syndrome

Genetic screening results just got harder to handle under new abortion rules

Genetic screening results just got harder to handle under new abortion rules

AAP recommends University of Kentucky HDI resources for families of infants with Down syndrome

AAP recommends University of Kentucky HDI resources for families of infants with Down syndrome

The effectiveness of sotrovimab vs. molnupiravir in preventing severe COVID-19 outcomes in non-hospitalized high-risk COVID-19 adult patients

The effectiveness of sotrovimab vs. molnupiravir in preventing severe COVID-19 outcomes in non-hospitalized high-risk COVID-19 adult patients

Heart complications uncommon for children and young adults after SARS-CoV-2 infection

Heart complications uncommon for children and young adults after SARS-CoV-2 infection

UW Medicine scientists contribute to the publication of first complete, gapless genome sequence

UW Medicine scientists contribute to the publication of first complete, gapless genome sequence

Exploring the drivers of Catatonia and Acute Regression in Down Syndrome

Exploring the drivers of Catatonia and Acute Regression in Down Syndrome

First genetic rat model of Down syndrome offers better understanding of the condition

First genetic rat model of Down syndrome offers better understanding of the condition

People with congenital heart defect hospitalized for COVID-19 are at highest risk of severe illness

People with congenital heart defect hospitalized for COVID-19 are at highest risk of severe illness

Inside the tactical tug of war over the controversial Alzheimer’s drug

Inside the tactical tug of war over the controversial Alzheimer’s drug