Down Syndrome

Down syndrome is a chromosomal abnormality characterized by the presence of an extra copy of genetic material on the 21st chromosome, either in whole (Trisomy 21) or in part (such as due to translocations). The effects of the extra copy vary greatly among people, depending on the extent of the extra copy, genetic history and pure chance. In 2007, the American College of Obstetricians and Gynecologists (ACOG) endorsed guidelines that offer risk assessment to all pregnancies for fetal chromosomal abnormalities, including Down syndrome. It is estimated that approximately 70%, or 2.8 million, women undergo Down syndrome screening in the United States each year.
What is Down Syndrome?

Down syndrome or Down's syndrome, is a congenital condition that usually causes some degree of learning disability and is typically characterized by certain physical features.

Read More

Overview

Feature Articles

Latest Down Syndrome News and Research

Artificial intelligence could help better predict the onset and course of cardiovascular disease

Artificial intelligence could help better predict the onset and course of cardiovascular disease

AI could lead to better ways to predict the onset and course of cardiovascular disease

AI could lead to better ways to predict the onset and course of cardiovascular disease

Recommended choline intake during pregnancy improves child's sustained attention

Recommended choline intake during pregnancy improves child's sustained attention

Tracking ADHD symptoms, behavior in people with intellectual disability using a smartphone app

Tracking ADHD symptoms, behavior in people with intellectual disability using a smartphone app

Study reveals how the blood and immune systems develop in prenatal bone marrow

Study reveals how the blood and immune systems develop in prenatal bone marrow

Scientists examine kids’ unique immune systems as more fall victim to covid

Scientists examine kids’ unique immune systems as more fall victim to covid

Researchers develop a machine learning-based screening tool for genetic syndromes in children

Researchers develop a machine learning-based screening tool for genetic syndromes in children

Study illuminates genetic understanding of aggressive childhood leukemias

Study illuminates genetic understanding of aggressive childhood leukemias

Telehealth helped physical therapists to provide essential care for pediatric patients during pandemic

Telehealth helped physical therapists to provide essential care for pediatric patients during pandemic

Obstructive sleep apnea may affect heart health and increase blood pressure in children

Obstructive sleep apnea may affect heart health and increase blood pressure in children

COVIDome Explorer online portal launched to accelerate COVID-19 research on a global scale

COVIDome Explorer online portal launched to accelerate COVID-19 research on a global scale

How a hospital and a school district teamed up to help kids in emotional crisis

How a hospital and a school district teamed up to help kids in emotional crisis

Feinstein Institutes awarded $2.9 million NIH funding for polygenic embryo selection studies

Feinstein Institutes awarded $2.9 million NIH funding for polygenic embryo selection studies

Optical genome mapping could change the existing workflow within cytogenetic laboratories

Optical genome mapping could change the existing workflow within cytogenetic laboratories

IU School of Medicine wins $30 million NIA funding to study Alzheimer’s disease and related dementias

IU School of Medicine wins $30 million NIA funding to study Alzheimer’s disease and related dementias

Study reveals risk factors associated with COVID-19 outcomes for people with IDD

Study reveals risk factors associated with COVID-19 outcomes for people with IDD

A single blood-based biomarker can help indicate underlying neurodegeneration

A single blood-based biomarker can help indicate underlying neurodegeneration

In California, nursing home owners can operate after they’re denied a license

In California, nursing home owners can operate after they’re denied a license

High seroprevalence in Peruvian population recovering from SARS-CoV-2 infection

High seroprevalence in Peruvian population recovering from SARS-CoV-2 infection

How schools can help kids heal after the pandemic’s uncertainty

How schools can help kids heal after the pandemic’s uncertainty