Down Syndrome

Down syndrome is a chromosomal abnormality characterized by the presence of an extra copy of genetic material on the 21st chromosome, either in whole (Trisomy 21) or in part (such as due to translocations). The effects of the extra copy vary greatly among people, depending on the extent of the extra copy, genetic history and pure chance. In 2007, the American College of Obstetricians and Gynecologists (ACOG) endorsed guidelines that offer risk assessment to all pregnancies for fetal chromosomal abnormalities, including Down syndrome. It is estimated that approximately 70%, or 2.8 million, women undergo Down syndrome screening in the United States each year.
What is Down Syndrome?

Down syndrome or Down's syndrome, is a congenital condition that usually causes some degree of learning disability and is typically characterized by certain physical features.

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Latest Down Syndrome News and Research

High-powered MRI detects subtle differences in the hippocampus of people with Down syndrome

High-powered MRI detects subtle differences in the hippocampus of people with Down syndrome

New tool helps measure communication development in youth with Down syndrome

New tool helps measure communication development in youth with Down syndrome

Study shows stronger link between Down syndrome and acute myeloid leukemia

Study shows stronger link between Down syndrome and acute myeloid leukemia

Families with sick kids on Medicaid seek easier access to out-of-state hospitals

Families with sick kids on Medicaid seek easier access to out-of-state hospitals

Metabolic dysfunction found in mouse models of neurodevelopmental disorders

Metabolic dysfunction found in mouse models of neurodevelopmental disorders

Study reveals reason behind high risk of leukemia in children with Down syndrome

Study reveals reason behind high risk of leukemia in children with Down syndrome

Sargramostim drug can also improve memory in people with mild-to-moderate Alzheimer's disease

Sargramostim drug can also improve memory in people with mild-to-moderate Alzheimer's disease

Study investigates the prevalence of eye disease in adults with Down syndrome

Study investigates the prevalence of eye disease in adults with Down syndrome

Human cerebral organoid model to screen drugs for treatment of Creutzfeldt-Jakob disease

Human cerebral organoid model to screen drugs for treatment of Creutzfeldt-Jakob disease

Push is on for states to ban organ transplant discrimination

Push is on for states to ban organ transplant discrimination

Study shows potential benefits of green tea extracts in Down syndrome

Study shows potential benefits of green tea extracts in Down syndrome

Adults with Down syndrome more likely to die from COVID-19 than general population

Adults with Down syndrome more likely to die from COVID-19 than general population

New partnership launches Down syndrome research biobank

New partnership launches Down syndrome research biobank

Woman’s right to disclosure of stillbirth could be achieved through a tort claim

Woman’s right to disclosure of stillbirth could be achieved through a tort claim

Pandemic sends a couple into indefinite long distance though just miles apart

Pandemic sends a couple into indefinite long distance though just miles apart

Vanderbilt researcher proposes an explanatory paradigm for the cause of autism

Vanderbilt researcher proposes an explanatory paradigm for the cause of autism

Study: Prenatal screening in Europe has reduced the number of babies born with Down syndrome

Study: Prenatal screening in Europe has reduced the number of babies born with Down syndrome

High error rates found in human egg cells

High error rates found in human egg cells

New study finds link between gestational age and ADHD in children with Down syndrome

New study finds link between gestational age and ADHD in children with Down syndrome

Experimental drug can reverse age-related memory decline in mice

Experimental drug can reverse age-related memory decline in mice